Comparison of cytochrome P450 3A enzymes in cynomolgus monkeys and humans

Drug Metabolism and Pharmacokinetics

Volumn 25, Issue 4, 2010, Pages 388-391

  Iwasaki, Kazuhide ^a   Murayama, Norie ^b   Koizumi, Ryo ^b   Uno, Yasuhiro ^a   Yamazaki, Hiroshi ^b  

^a SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Cynomolgus monkey; CYP3A4; CYP3A5; Human

Indexed keywords

BUFURALOL; COUMARIN; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DEXTROMETHORPHAN; DICLOFENAC; ETHOXYRESORUFIN; FLURBIPROFEN; MEPHENYTOIN; PACLITAXEL; PENTOXYRESORUFIN;

ANIMAL CELL; BACTERIAL MEMBRANE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEALKYLATION; DEMETHYLATION; DRUG HYDROXYLATION; DRUG OXIDATION; DRUG SELECTIVITY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; HUMAN; HUMAN CELL; HUMAN VERSUS ANIMAL COMPARISON; LIVER MICROSOME; MACACA; NONHUMAN; NOTE; PROTEIN EXPRESSION;

EID: 77956956713     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.DMPK-10-NT-022     Document Type: Note

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