Short communication genetic variants of CYP3A4 and CYP3A5 in cynomolgus and rhesus macaques

Drug Metabolism and Disposition

Volumn 38, Issue 2, 2010, Pages 209-214

  Uno, Yasuhiro ^a   Matsushita, Akinori ^a   Osada, Naoki ^b   Uehara, Shotaro ^a   Kohara, Sakae ^a   Nagata, Ryoichi ^a   Fukuzaki, Koichiro ^a   Utoh, Masahiro ^a   Murayama, Norie ^c   Yamazaki, Hiroshi ^c  

^a SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^c SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ASPARAGINE; CYSTEINE; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; GLYCINE; HEME; LEUCINE; METHIONINE; MIDAZOLAM; MUTANT PROTEIN; NIFEDIPINE; PROTEIN; SERINE; THREONINE; VALINE; CYTOCHROME P450 3A; DNA; ISOENZYME; RECOMBINANT PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CHINESE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE DELETION; GENE EXPRESSION; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC SCREENING; GENETIC VARIABILITY; GENOME; INDONESIA; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PURIFICATION; RHESUS MONKEY; ANIMAL; CHINA; COMPARATIVE STUDY; DNA SEQUENCE; GENETICS; HUMAN; INTRON; ISOLATION AND PURIFICATION; MACACA; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHEAST ASIA;

ANIMALIA; ESCHERICHIA COLI; MACACA; MACACA MULATTA;

ANIMALS; ASIA, SOUTHEASTERN; CHINA; CYTOCHROME P-450 CYP3A; DNA; GENETIC VARIATION; HUMANS; INTRONS; ISOENZYMES; MACACA FASCICULARIS; MACACA MULATTA; MIDAZOLAM; NIFEDIPINE; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

EID: 76149140867     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.029710     Document Type: Article

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