-
1
-
-
0034883804
-
Uncoupling proteins: Functional characteristics and role in the pathogenesis of obesity and Type II diabetes
-
DOI 10.1007/s001250100596
-
Dalgaard LT, Pedersen O (2001) Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and type II diabetes. Diabetologia 44:946-965 (Pubitemid 32778126)
-
(2001)
Diabetologia
, vol.44
, Issue.8
, pp. 946-965
-
-
Dalgaard, L.T.1
Pedersen, O.2
-
2
-
-
0031019249
-
Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinemia
-
DOI 10.1038/ng0397-269
-
Fleury C, Neverova M, Collins S et al (1997) Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat Genet 15:269-272 (Pubitemid 27098720)
-
(1997)
Nature Genetics
, vol.15
, Issue.3
, pp. 269-272
-
-
Fleury, C.1
Neverova, M.2
Collins, S.3
Raimbault, S.4
Champigny, O.5
Levi-Meyrueis, C.6
Bouillaud, F.7
Seldin, M.F.8
Surwit, R.S.9
Ricquier, D.10
Warden, C.H.11
-
3
-
-
0030803678
-
The human uncoupling protein-3 gene. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts
-
DOI 10.1074/jbc.272.41.25433
-
Solanes G, Vidal-Puig A, Grujic D, Flier JS, Lowell BB (1997) The human uncoupling protein-3 gene. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts. J Biol Chem 272:25433-25436 (Pubitemid 27438845)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.41
, pp. 25433-25436
-
-
Solanes, G.1
Vidal-Puig, A.2
Grujic, D.3
Flier, J.S.4
Lowell, B.B.5
-
5
-
-
33751269135
-
Regulation of insulin secretion by uncoupling protein
-
DOI 10.1042/BST0340802
-
Chan CB, Kashemsant N (2006) Regulation of insulin secretion by uncoupling protein. Biochem Soc Trans 34:802-805 (Pubitemid 44796425)
-
(2006)
Biochemical Society Transactions
, vol.34
, Issue.5
, pp. 802-805
-
-
Chan, C.B.1
Kashemsant, N.2
-
6
-
-
33947618988
-
Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action
-
DOI 10.1096/fj.06-7148com
-
de Souza CT, Araujo EP, Stoppiglia LF et al (2007) Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action. FASEB J 21:1153-1163 (Pubitemid 46495705)
-
(2007)
FASEB Journal
, vol.21
, Issue.4
, pp. 1153-1163
-
-
De Souza, C.T.1
Araujo, E.P.2
Stoppiglia, L.F.3
Pauli, J.R.4
Ropelle, E.5
Rocco, S.A.6
Marin, R.M.7
Franchini, K.G.8
Carvalheira, J.B.9
Saad, M.J.10
Boschero, A.C.11
Carneiro, E.M.12
Velloso, L.A.13
-
7
-
-
0034990987
-
Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: Mechanism of action
-
Chan CB, DeLeo D, Joseph JWet al (2001) Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucosestimulated insulin secretion: mechanism of action. Diabetes 50:1302-1310 (Pubitemid 32500162)
-
(2001)
Diabetes
, vol.50
, Issue.6
, pp. 1302-1310
-
-
Chan, C.B.1
De Leo, D.2
Joseph, J.W.3
McQuaid, T.S.4
Ha, X.F.5
Xu, F.6
Tsushima, R.G.7
Pennefather, P.S.8
Salapatek, A.M.F.9
Wheeler, M.B.10
-
8
-
-
0035875087
-
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes
-
DOI 10.1016/S0092-8674(01)00378-6
-
Zhang CY, Baffy G, Perret P et al (2001) Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. Cell 105:745-755 (Pubitemid 32635104)
-
(2001)
Cell
, vol.105
, Issue.6
, pp. 745-755
-
-
Zhang, C.-Y.1
Baffy, G.2
Perret, P.3
Krauss, S.4
Peroni, O.5
Grujic, D.6
Hagen, T.7
Vidal-Puig, A.J.8
Boss, O.9
Kim, Y.-B.10
Zheng, X.X.11
Wheeler, M.B.12
Shulman, G.I.13
Chan, C.B.14
Lowell, B.B.15
-
9
-
-
0031682078
-
Uncoupling protein 3 is reduced in skeletal muscle of NIDDM patients
-
Krook A, Digby J, O'Rahilly S, Zierath JR, Wallberg-Henriksson H (1998) Uncoupling protein 3 is reduced in skeletal muscle of NIDDM patients. Diabetes 47:1528-1531 (Pubitemid 28396961)
-
(1998)
Diabetes
, vol.47
, Issue.9
, pp. 1528-1531
-
-
Krook, A.1
Digby, J.2
O'Rahilly, S.3
Zierath, J.R.4
Wallberg-Henriksson, H.5
-
10
-
-
69449089547
-
The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes
-
Jia JJ, Zhang X, Ge CR, Jois M (2009) The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes. Obes Rev 10:519-552
-
(2009)
Obes Rev
, vol.10
, pp. 519-552
-
-
Jia, J.J.1
Zhang, X.2
Ge, C.R.3
Jois, M.4
-
11
-
-
0036830548
-
A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans
-
Krempler F, Esterbauer H, Weitgasser R et al (2002) A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans. Diabetes 51:3331-3335 (Pubitemid 35246982)
-
(2002)
Diabetes
, vol.51
, Issue.11
, pp. 3331-3335
-
-
Krempler, F.1
Esterbauer, H.2
Weitgasser, R.3
Ebenbichler, C.4
Patsch, J.R.5
Miller, K.6
Xie, M.7
Linnemayr, V.8
Oberkofler, H.9
Patsch, W.10
-
12
-
-
0034972150
-
A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans
-
DOI 10.1038/88911
-
Esterbauer H, Schneitler C, Oberkofier H et al (2001) A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans. Nat Genet 28:178-183 (Pubitemid 32538066)
-
(2001)
Nature Genetics
, vol.28
, Issue.2
, pp. 178-183
-
-
Esterbauer, H.1
Schneitler, C.2
Oberkofler, H.3
Ebenbichler, C.4
Paulweber, B.5
Sandhofer, F.6
Ladurner, G.7
Hell, E.8
Strosberg, A.D.9
Patsch, J.R.10
Krempler, F.11
Patsch, W.12
-
13
-
-
3042698328
-
The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes
-
DOI 10.2337/diabetes.53.7.1905
-
D'Adamo M, Perego L, Cardellini M et al (2004) The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes. Diabetes 53:1905-1910 (Pubitemid 38857052)
-
(2004)
Diabetes
, vol.53
, Issue.7
, pp. 1905-1910
-
-
D'Adamo, M.1
Perego, L.2
Cardellini, M.3
Marini, M.A.4
Frontoni, S.5
Andreozzi, F.6
Sciacqua, A.7
Lauro, D.8
Sbraccia, P.9
Federici, M.10
Paganelli, M.11
Pontiroli, A.E.12
Lauro, R.13
Perticone, F.14
Folli, F.15
Sesti, G.16
-
14
-
-
10744222893
-
Uncoupling Protein 2 Promoter Polymorphism - 866G/A Affects Its Expression in beta-Cells and Modulates Clinical Profiles of Japanese Type 2 Diabetic Patients
-
DOI 10.2337/diabetes.53.2.482
-
Sasahara M, Nishi M, Kawashima H et al (2004) Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients. Diabetes 53:482-485 (Pubitemid 38174566)
-
(2004)
Diabetes
, vol.53
, Issue.2
, pp. 482-485
-
-
Sasahara, M.1
Nishi, M.2
Kawashima, H.3
Ueda, K.4
Sakagashira, S.5
Furuta, H.6
Matsumoto, E.7
Hanabusa, T.8
Sasaki, H.9
Nanjo, K.10
-
15
-
-
12444292715
-
A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects
-
DOI 10.2337/diabetes.52.5.1280
-
Sesti G, Cardellini M, Marini MA et al (2003) A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects. Diabetes 52:1280-1283 (Pubitemid 36523369)
-
(2003)
Diabetes
, vol.52
, Issue.5
, pp. 1280-1283
-
-
Sesti, G.1
Cardellini, M.2
Marini, M.A.3
Frontoni, S.4
D'Adamo, M.5
Del Guerra, S.6
Lauro, D.7
De Nicolais, P.8
Sbraccia, P.9
Del Prato, S.10
Gambardella, S.11
Federici, M.12
Marchetti, P.13
Lauro, R.14
-
16
-
-
0032830889
-
Impact of the v/v 55 polymorphism of the uncoupling protein 2 gene on 24-h energy expenditure and substrate oxidation
-
Astrup A, Toubro S, Dalgaard LT, Urhammer SA, Sorensen TI, Pedersen O (1999) Impact of the v/v 55 polymorphism of the uncoupling protein 2 gene on 24-h energy expenditure and substrate oxidation. Int J Obes Relat Metab Disord 23:1030-1034 (Pubitemid 29476205)
-
(1999)
International Journal of Obesity
, vol.23
, Issue.10
, pp. 1030-1034
-
-
Astrup, A.1
Toubro, S.2
Dalgaard, L.T.3
Urhammer, S.A.4
Sorensen, T.I.A.5
Pedersen, O.6
-
17
-
-
23044461195
-
The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: The CARDIA study
-
DOI 10.1373/clinchem.2004.044859
-
Yu X, Jacobs DR, Schreiner PJ, Gross MD, Steffes MW, Fornage M (2005) The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA Study. Clin Chem 51:1451-1456 (Pubitemid 41060877)
-
(2005)
Clinical Chemistry
, vol.51
, Issue.8
, pp. 1451-1456
-
-
Yu, X.1
Jacobs Jr., D.R.2
Schreiner, P.J.3
Gross, M.D.4
Steffes, M.W.5
Fornage, M.6
-
18
-
-
7344220905
-
Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima Indians
-
DOI 10.1093/hmg/7.9.1431
-
Walder K, Norman RA, Hanson RL et al (1998) Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima Indians. Hum Mol Genet 7:1431-1435 (Pubitemid 28429924)
-
(1998)
Human Molecular Genetics
, vol.7
, Issue.9
, pp. 1431-1435
-
-
Walder, K.1
Norman, R.A.2
Hanson, R.L.3
Schrauwen, P.4
Neverova, M.5
Jenkinson, C.P.6
Easlick, J.7
Warden, C.H.8
Pecqueur, C.9
Raimbault, S.10
Ricquier, D.11
Harper, M.12
Silver, K.13
Shuldiner, A.R.14
Solanes, G.15
Lowell, B.B.16
Chung, W.K.17
Leibel, R.L.18
Pratley, R.19
Ravussin, E.20
more..
-
19
-
-
0033735893
-
An uncoupling protein 3 gene polymorphism associated with a lower risk of developing type II diabetes and with atherogenic lipid profile in a French cohort
-
Meirhaeghe A, Amouyel P, Helbecque N et al (2000) An uncoupling protein 3 gene polymorphism associated with a lower risk of developing type II diabetes and with atherogenic lipid profile in a French cohort. Diabetologia 43:1424-1428
-
(2000)
Diabetologia
, vol.43
, pp. 1424-1428
-
-
Meirhaeghe, A.1
Amouyel, P.2
Helbecque, N.3
-
20
-
-
0032583387
-
Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
-
DOI 10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0. CO;2-8
-
Parmar MKB, Torri V, Stewart L (1998) Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med 17:2815-2834 (Pubitemid 28562978)
-
(1998)
Statistics in Medicine
, vol.17
, Issue.24
, pp. 2815-2834
-
-
Parmar, M.K.B.1
Torri, V.2
Stewart, L.3
-
21
-
-
0037098199
-
Quantifying heterogeneity in a meta-analysis
-
DOI 10.1002/sim.1186
-
Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539-1558 (Pubitemid 34746062)
-
(2002)
Statistics in Medicine
, vol.21
, Issue.11
, pp. 1539-1558
-
-
Higgins, J.P.T.1
Thompson, S.G.2
-
23
-
-
0025215247
-
Power and sample size calculations. A review and computer program
-
DOI 10.1016/0197-2456(90)90005-M
-
Dupont WD, Plummer WD Jr (1990) Power and sample size calculations. A review and computer program. Control Clin Trials 11:116-128 (Pubitemid 20136185)
-
(1990)
Controlled Clinical Trials
, vol.11
, Issue.2
, pp. 116-128
-
-
Dupont, W.D.1
Plummer Jr., W.D.2
-
24
-
-
1642295096
-
Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
-
Wacholder S, Chanock S, Garcia-Closas M, ElGhormli L, Rothman N (2004) Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 96:434-442 (Pubitemid 38443646)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.6
, pp. 434-442
-
-
Wacholder, S.1
Chanock, S.2
Garcia-Closas, M.3
El Ghormli, L.4
Rothman, N.5
-
25
-
-
33748090675
-
A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints
-
DOI 10.1002/sim.2380
-
Harbord RM, Egger M, Sterne JA (2006) A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints. Stat Med 25:3443-3457 (Pubitemid 44575162)
-
(2006)
Statistics in Medicine
, vol.25
, Issue.20
, pp. 3443-3457
-
-
Harbord, R.M.1
Egger, M.2
Sterne, J.A.C.3
-
26
-
-
0346787545
-
Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion
-
Wang H, Chu WS, Lu T, Hasstedt SJ, Kern PA, Elbein SC (2004) Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion. Am J Physiol Endocrinol Metab 286:E1-E7 (Pubitemid 38036602)
-
(2004)
American Journal of Physiology - Endocrinology and Metabolism
, vol.286
, Issue.1
-
-
Wang, H.1
Chu, W.S.2
Lu, T.3
Hasstedt, S.J.4
Kern, P.A.5
Elbein, S.C.6
-
27
-
-
10744229041
-
A common polymorphism of uncoupling protein 2 gene is associated with hypertension
-
DOI 10.1097/00004872-200401000-00018
-
Ji Q, Ikegami H, Fujisawa T et al (2004) A common polymorphism of uncoupling protein 2 gene is associated with hypertension. J Hypertens 22:97-102 (Pubitemid 38293536)
-
(2004)
Journal of Hypertension
, vol.22
, Issue.1
, pp. 97-102
-
-
Ji, Q.1
Ikegami, H.2
Fujisawa, T.3
Kawabata, Y.4
Ono, M.5
Nishino, M.6
Ohishi, M.7
Katsuya, T.8
Rakugi, H.9
Ogihara, T.10
-
28
-
-
14044254272
-
The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy
-
DOI 10.1210/jc.2004-1072
-
Bulotta A, Ludovico O, Coco A et al (2005) The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy. J Clin Endocrinol Metab 90:1176-1180 (Pubitemid 40279251)
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, Issue.2
, pp. 1176-1180
-
-
Bulotta, A.1
Ludovico, O.2
Coco, A.3
Di Paola, R.4
Quattrone, A.5
Carella, M.6
Pellegrini, F.7
Prudente, S.8
Trischitta, V.9
-
29
-
-
33845800258
-
Beta2-adrenergic receptor and UCP3 variants modulate the relationship between age and type 2 diabetes mellitus
-
Pinelli M, Giacchetti M, Acquaviva F et al (2006) Beta2-adrenergic receptor and UCP3 variants modulate the relationship between age and type 2 diabetes mellitus. BMC Med Genet 7:85
-
(2006)
BMC Med Genet
, vol.7
, pp. 85
-
-
Pinelli, M.1
Giacchetti, M.2
Acquaviva, F.3
-
30
-
-
42449114459
-
Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the women's health initiative observational study
-
Hsu YH, Niu T, Song Y, Tinker L, Kuller LH, Liu S (2008) Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the women's health initiative observational study. Diabetes 57:1101-1107
-
(2008)
Diabetes
, vol.57
, pp. 1101-1107
-
-
Hsu, Y.H.1
Niu, T.2
Song, Y.3
Tinker, L.4
Kuller, L.H.5
Liu, S.6
-
31
-
-
54249088345
-
Associations between polymorphisms in the mitochondrial uncoupling proteins (UCPs) with T2DM
-
Lee HJ, Ryu HJ, Shin HD et al (2008) Associations between polymorphisms in the mitochondrial uncoupling proteins (UCPs) with T2DM. Clin Chim Acta 398:27-33
-
(2008)
Clin Chim Acta
, vol.398
, pp. 27-33
-
-
Lee, H.J.1
Ryu, H.J.2
Shin, H.D.3
-
32
-
-
77950654523
-
Interaction between the UCP2 -866G>A polymorphism, diabetes, and betablocker use among patients with acute coronary syndromes
-
Beitelshees AL, Finck BN, Leone TC et al (2010) Interaction between the UCP2 -866G>A polymorphism, diabetes, and betablocker use among patients with acute coronary syndromes. Pharmacogenet Genomics 20:231-238
-
(2010)
Pharmacogenet Genomics
, vol.20
, pp. 231-238
-
-
Beitelshees, A.L.1
Finck, B.N.2
Leone, T.C.3
-
33
-
-
78149259769
-
Association study of the -866G/A UCP2 gene promoter polymorphism with type 2 diabetes and obesity in a Tehran population: A case control study
-
Heidari J, Akrami SM, Heshmat R, Amiri P, Fakhrzadeh H, Pajouhi M (2010) Association study of the -866G/A UCP2 gene promoter polymorphism with type 2 diabetes and obesity in a Tehran population: a case control study. Arch Iran Med 13:384-390
-
(2010)
Arch Iran Med
, vol.13
, pp. 384-390
-
-
Heidari, J.1
Akrami, S.M.2
Heshmat, R.3
Amiri, P.4
Fakhrzadeh, H.5
Pajouhi, M.6
-
34
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
Voight BF, Scott LJ, Steinthorsdottir Vet al (2010) Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 42:579-589
-
(2010)
Nat Genet
, vol.42
, pp. 579-589
-
-
Voight, B.F.1
Scott, L.J.2
Steinthorsdottir, V.3
-
35
-
-
78650604639
-
Uncoupling protein 2 and 3 gene polymorphisms and their association with type 2 diabetes in Asian Indians
-
Vimaleswaran KS, Radha V, Ghosh S,Majumder PP, Sathyanarayana Rao MR, Mohan V (2011) Uncoupling protein 2 and 3 gene polymorphisms and their association with type 2 diabetes in Asian Indians. Diabetes Technol Ther 13:19-25
-
(2011)
Diabetes Technol Ther
, vol.13
, pp. 19-25
-
-
Vimaleswaran, K.S.1
Radha, V.2
Ghosh Smajumder, P.P.3
Sathyanarayana Rao, M.R.4
Mohan, V.5
-
36
-
-
15444342187
-
Molecular screening of uncoupling protein 2 gene in patients with noninsulin-dependent diabetes mellitus or obesity
-
DOI 10.1210/jc.83.8.2800
-
Kubota T, Mori H, Tamori Yet al (1998) Molecular screening of uncoupling protein 2 gene in patients with noninsulin-dependent diabetes mellitus or obesity. J Clin Endocrinol Metab 83:2800-2804 (Pubitemid 28493779)
-
(1998)
Journal of Clinical Endocrinology and Metabolism
, vol.83
, Issue.8
, pp. 2800-2804
-
-
Kubota, T.1
Mori, H.2
Tamori, Y.3
Okazawa, H.4
Fukuda, T.5
Miki, M.6
Ito, C.7
Fleury, C.8
Bouillaud, F.9
Kasuga, M.10
-
37
-
-
1842866369
-
Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus
-
DOI 10.1007/s00125-003-1321-3
-
Cho YM, Ritchie MD, Moore JH et al (2004) Multifactordimensionality reduction shows a two-locus interaction associated with type 2 diabetes mellitus. Diabetologia 47:549-554 (Pubitemid 38491253)
-
(2004)
Diabetologia
, vol.47
, Issue.3
, pp. 549-554
-
-
Cho, Y.M.1
Ritchie, M.D.2
Moore, J.H.3
Park, J.Y.4
Lee, K.-U.5
Shin, H.D.6
Lee, H.K.7
Park, K.S.8
-
38
-
-
0034884629
-
The uncoupling protein 3-55 Cgt;T variant is not associated with type II diabetes mellitus in Danish subjects [3]
-
DOI 10.1007/s001250100579
-
Dalgaard LT, Hansen T, Urhammer SA, Drivsholm T, Borch-Johnsen K, Pedersen O (2001) The uncoupling protein 3-55 C>T variant is not associated with Type II diabetes mellitus in Danish subjects. Diabetologia 44:1065-1067 (Pubitemid 32778143)
-
(2001)
Diabetologia
, vol.44
, Issue.8
, pp. 1065-1067
-
-
Dalgaard, L.T.1
Hansen, T.2
Urhammer, S.A.3
Drivsholm, T.4
Borch-Johnsen, K.5
Pedersen, O.6
-
39
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
DOI 10.1126/science.1142358
-
Saxena R, Voight BF, Lyssenko V et al (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316:1331-1336 (Pubitemid 46871653)
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
De Bakker, P.I.W.5
Chen, H.6
Roix, J.J.7
Kathiresan, S.8
Hirschhorn, J.N.9
Daly, M.J.10
Hughes, T.E.11
Groop, L.12
Altshuler, D.13
-
40
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in finns detects multiple susceptibility variants
-
DOI 10.1126/science.1142382
-
Scott LJ, Mohlke KL, Bonnycastle LL et al (2007) A genomewide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316:1341-1345 (Pubitemid 46871655)
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
Duren, W.L.6
Erdos, M.R.7
Stringham, H.M.8
Chines, P.S.9
Jackson, A.U.10
Prokunina-Olsson, L.11
Ding, C.-J.12
Swift, A.J.13
Narisu14
Hu, T.15
Pruim, R.16
Xiao, R.17
Li, X.-Y.18
Conneely, K.N.19
Riebow, N.L.20
Sprau, A.G.21
Tong, M.22
White, P.P.23
Hetrick, K.N.24
Barnhart, M.W.25
Bark, C.W.26
Goldstein, J.L.27
Watkins, L.28
Xiang, F.29
Saramies, J.30
Buchanan, T.A.31
Watanabe, R.M.32
Valle, T.T.33
Kinnunen, L.34
Abecasis, G.R.35
Pugh, E.W.36
Doheny, K.F.37
Bergman, R.N.38
Tuomilehto, J.39
Collins, F.S.40
Boehnke, M.41
more..
-
41
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447:661-678
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
42
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
DOI 10.1126/science.1142364
-
Zeggini E, Weedon MN, Lindgren CM et al (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316:1336-1341 (Pubitemid 46871654)
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
Lango, H.6
Timpson, N.J.7
Perry, J.R.B.8
Rayner, N.W.9
Freathy, R.M.10
Barrett, J.C.11
Shields, B.12
Morris, A.P.13
Ellard, S.14
Groves, C.J.15
Harries, L.W.16
Marchini, J.L.17
Owen, K.R.18
Knight, B.19
Cardon, L.R.20
Walker, M.21
Hitman, G.A.22
Morris, A.D.23
Doney, A.S.F.24
McCarthy, M.I.25
Hattersley, A.T.26
Bruce, I.N.27
Donovan, H.28
Eyre, S.29
Gilbert, P.D.30
Hider, S.L.31
Hinks, A.M.32
John, S.L.33
Potter, C.34
Silman, A.J.35
Symmons, D.P.M.36
Thomson, W.37
Worthington, J.38
more..
-
43
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R, Rocheleau G, Rung J et al (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445:881-885
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
-
44
-
-
78649842241
-
Genomics, type 2 diabetes, and obesity
-
McCarthy MI (2010) Genomics, type 2 diabetes, and obesity. N Engl J Med 363:2339-2350
-
(2010)
N Engl J Med
, vol.363
, pp. 2339-2350
-
-
McCarthy, M.I.1
-
45
-
-
4143145303
-
Meta-analysis of genetic association studies
-
DOI 10.1016/j.tig.2004.06.014, PII S0168952504001799
-
Munafo MR, Flint J (2008) Meta-analysis of genetic association studies. Trends Genet 20:439-444 (Pubitemid 39094573)
-
(2004)
Trends in Genetics
, vol.20
, Issue.9
, pp. 439-444
-
-
Munafo, M.R.1
Flint, J.2
-
46
-
-
53349173117
-
Sensitivity of between-study heterogeneity in meta-analysis: Proposed metrics and empirical evaluation
-
Patsopoulos NA, Evangelou E, Ioannidis JP (2008) Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation. Int J Epidemiol 37:1148-1157
-
(2008)
Int J Epidemiol
, vol.37
, pp. 1148-1157
-
-
Patsopoulos, N.A.1
Evangelou, E.2
Ioannidis, J.P.3
-
47
-
-
77950223717
-
Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus
-
Crispim D, Fagundes NJ, dos Santos KG et al (2010) Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus. Clin Endocrinol (Oxf) 72:612-619
-
(2010)
Clin Endocrinol (Oxf)
, vol.72
, pp. 612-619
-
-
Crispim, D.1
Fagundes, N.J.2
Dos Santos, K.G.3
-
48
-
-
42449098483
-
The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men
-
Cheurfa N, Dubois-Laforgue D, Ferrarezi DA et al (2008) The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men. Diabetes 57:1063-1068
-
(2008)
Diabetes
, vol.57
, pp. 1063-1068
-
-
Cheurfa, N.1
Dubois-Laforgue, D.2
Ferrarezi, D.A.3
|