The human uncoupling protein-3 gene. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts

Journal of Biological Chemistry

Volumn 272, Issue 41, 1997, Pages 25433-25436

  Solanes, Gemma ^a   Vidal Puig, Antonio ^a   Grujic, Danica ^a   Flier, Jeffrey S ^a   Lowell, Bradford B ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

UNCOUPLING PROTEIN;

ARTICLE; CHROMOSOME 11Q; CHROMOSOME 7; GENE DUPLICATION; GENE MAPPING; GENE STRUCTURE; GENETIC LINKAGE; HUMAN; HUMAN CELL; OBESITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUANTITATIVE TRAIT; SKELETAL MUSCLE; THERMOGENESIS;

ANIMALS; BODY TEMPERATURE REGULATION; CARRIER PROTEINS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 11; CLONING, MOLECULAR; EXONS; HUMANS; INTRONS; ION CHANNELS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; RIBONUCLEASES; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0030803678     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.41.25433     Document Type: Article

References (34)

1. Ravussin, E., and Swinburn, B. A. (1996) Diabetes Rev. 4, 403-422
2. Himms-Hagen, J. (1989) Prog. Lipid Res. 28, 67-115
3. Jacobsson, A., Stadler, U., Glotzer, M. A., and Kozak, L. P. (1985) J. Biol. Chem. 260, 16250-16254
4. Bouillaud, F., Weissenbach, J., and Ricquier, D. (1986) J. Biol. Chem. 261, 1487-1490
5. Nicholls, D. G., and Locke, R. M. (1984) Physiol. Rev. 64, 1-64
6. Klingenberg, M. (1990) Trends Biochem. Sci. 15, 108-112
7. Enerback, S., Jacobsson, A., Simpson, E. M., Guerra, C., Yamashita, H., Harper, M. E., and Kozak, L. P. (1997) Nature 387, 90-94
8. Astrup, A., Bulow, J., Madsen, J., and Christensen, N. J. (1985) Am. J. Physiol. 248, E507-E515
9. Astrup, A., Simonsen, L., Bulow, J., Madsen, J., and Christensen, N. J. (1989) Am. J. Physiol. 257, E340-E345
10. Zurlo, F., Larson, K., Bogardus, C., and Ravussin, E. (1990) J. Clin. Invest. 86, 1423-1427
11. Simonsen, L., Bulow, J., Madsen, J., and Christensen, N. J. (1992) Am. J. Physiol. 263, E850-E855
12. Spraul, M., Ravussin, E., Fontvieille, A. M., Rising, R., Larson, D. E., and Anderson, E. A. (1993) J. Clin. Invest. 92, 1730-1735
13. Fleury, C., Neverova, M., Collins, S., Raimbault, S., Champigny, O., Levi-Meyrueis, C., Bouillaud, F., Seldin, M. F., Surwit, R. S., Ricquier, D., and Warden, C. H. (1997) Nat. Genet. 15, 269-272
14. Gimeno, R. E., Dembski, M., Weng, X., Shyjan, A. W., Gimeno, C. J., Iris, F., Ellis, S. J., Deng, N., Woolf, E. A., and Tartaglia, L. A. (1997) Diabetes 46, 900-906
15. Boss, O., Samec, S., Paoloni-Giacobino, A., Rossier, C., Dulloo, A., Seydoux, J., Muzzin, P., and Giacobino, J.-P. (1997) FEBS Lett. 408, 39-42
16. Vidal-Puig, A., Solanes, G., Grujic, D., Flier, J. S., and Lowell, B. B. (1997) Biochem. Biophys. Res. Commun. 235, 79-82
17. Murdza-Inglis, D. L., Modriansky, M., Patel, H. V., Woldegiorgis, G., Freeman, K. B., and Garlid, K. D. (1994) J. Biol. Chem. 269, 7435-7438
18. Bouillaud, F., Arechaga, I., Petit, P. X., Raimbault, S., Levi-Meyrueis, C., Casteilla, L., Laurent, M., Rial, E., and Ricquier, D. (1994) EMBO J. 13, 1990-1997
19. Vidal-Puig, A., Jimenez-Linan, M., Lowell, B. B., Hamann, A., Hu, E., Spiegelman, B., Flier, J. S., and Moller, D. E. (1996) J. Clin. Invest. 97, 2553-2561
20. Cox, D. R., Burmeister, M., Price, E. R., Kim, S., and Myers, R. M. (1990) Science 250, 245-250
21. Walter, M. A., Spillett, D. J., Thomas, P., Weissenbach, J., and Goodfellow, P. N. (1994) Nat. Genet. 7, 22-28
22. Hudson, T. J., Stein, L. D., Gerety, S. S., Ma, J., Castle, A. B., Silva, J., Slonim, D. K., Baptista, R., Kruglyak, L., Xu, S. H., et al. (1995) Science 270, 1945-1954
23. Dib, C., Faure, S., Fizames, C., Samson, D., Drouot, N., Vignal, A., Millasseau, P., Marc, S., Hazan, J., Seboun, E., Lathrop, M., Gyapay, G., Morissette, J., and Weissenbach, J. (1996) Nature 380, 152-154
24. Cassard, A. M., Bouillaud, F., Mattei, M. G., Hentz, E., Raimbault, S., Thomas, M., and Ricquier, D. (1990) J. Cell. Biochem. 43, 255-264
25. Michelson, A. M., and Orkin, S. H. (1983) J. Biol. Chem. 258, 15245-15254
26. White, P. C., and New, M. I. (1992) J. Clin. Endocrinol. Metab. 74, 6-11
27. Lifton, R. P., Dluhy, R. G., Powers, M., Rich, G. M., Cook, S., Ulick, S., and Lalouel, J. M. (1992) Nature 355, 262-265
28. Warden, C. H., Fisler, J. S., Pace, M. J., Svenson, K. L., and Lusis, A. J. (1993) J. Clin. Invest. 92, 773-779
29. Seldin, M. F., Mott, D., Bhat, D., Petro, A., Kuhn, C. M., Kingsmore, S. F., Bogardus, C., Opara, E., Feinglos, M. N., and Surwit, R. S. (1994) J. Clin. Invest. 94, 269-276
30. Taylor, B. A., and Phillips, S. J. (1996) Genomics 34, 389-398
31. Warden, C. H., Fisler, J. S., Shoemaker, S. M., Wen, P. Z., Svenson, K. L., Pace, M. J., and Lusis, A. J. (1995) J. Clin. Invest. 95, 1545-1552
32. Leppert, M., Baird, L., Anderson, K. L., Otterud, B., Lupski, J. R., and Lewis, R. A. (1994) Nat. Genet. 7, 108-112
33. Beales, P. L., Warner, A. M., Hitman, G. A., Thakker, R., and Flinter, F. A. (1997) J. Med. Genet. 34, 92-98
34. Bruford, E. A., Riise, R., Teague, P. W., Porter, K., Thomson, K. L., Moore, A. T., Jay, M., Warburg, M., Schinzel, A., Tommerup, N., Tornqvist, K., Rosenberg, T., Patton, M., Mansfield, D. C., and Wright, A. F. (1997) Genomics 41, 93-99