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Volumn 32, Issue 36, 2011, Pages 9908-9924

Accelerated gene transfer through a polysorbitol-based transporter mechanism

Author keywords

Accelerated transfection; COX 2 inhibitor; Gene transfer; Polysorbitol; Transporter

Indexed keywords

ACCELERATED TRANSFECTION; BUFFERING CAPACITIES; CELLULAR UPTAKE; COX-2 INHIBITORS; CYCLOOXYGENASES; DIAGNOSTIC AGENTS; HYDROXYL GROUPS; IN-VITRO; NANO-SIZED; POLYETHYLENIMINES; POLYSORBITOL; POLYVALENCY; POTENTIAL SYSTEMS; SMALL INTERFERING RNA; SPECIFIC INHIBITORS; TRANSFECTION ABILITY; TRANSFER CAPABILITY; TRANSPORTER;

EID: 80054081201     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.09.013     Document Type: Article
Times cited : (44)

References (51)
  • 1
    • 33744805790 scopus 로고    scopus 로고
    • Polymers for gene delivery across length scales
    • Putnam D. Polymers for gene delivery across length scales. Nat Mater 2006, 5:439-451.
    • (2006) Nat Mater , vol.5 , pp. 439-451
    • Putnam, D.1
  • 2
    • 0034328925 scopus 로고    scopus 로고
    • Gene therapy: trials and tribulations
    • Somia N., Verma I.M. Gene therapy: trials and tribulations. Nat Rev Genet 2000, 1:91-99.
    • (2000) Nat Rev Genet , vol.1 , pp. 91-99
    • Somia, N.1    Verma, I.M.2
  • 3
    • 0042311016 scopus 로고    scopus 로고
    • Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery
    • Anderson D.G., Lynn D.M., Langer R. Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery. Angew Chem Int Ed Engl 2003, 42:3153-3158.
    • (2003) Angew Chem Int Ed Engl , vol.42 , pp. 3153-3158
    • Anderson, D.G.1    Lynn, D.M.2    Langer, R.3
  • 4
    • 34247582332 scopus 로고    scopus 로고
    • SiRNA delivery into human T cells and primary cells with carbon-nanotube transporters
    • Liu Z., Winters M., Holodniy M., Dai H. siRNA delivery into human T cells and primary cells with carbon-nanotube transporters. Angew Chem Int Ed Engl 2007, 46:2023-2027.
    • (2007) Angew Chem Int Ed Engl , vol.46 , pp. 2023-2027
    • Liu, Z.1    Winters, M.2    Holodniy, M.3    Dai, H.4
  • 5
    • 34547728730 scopus 로고    scopus 로고
    • Guanidine-containing molecular transporters: sorbitol-based transporters show high intracellular selectivity toward mitochondria
    • Maiti K.K., Lee W.S., Takeuchi T., Watkins C., Fretz M., Kim D.C., et al. Guanidine-containing molecular transporters: sorbitol-based transporters show high intracellular selectivity toward mitochondria. Angew Chem Int Ed Engl 2007, 46:5880-5884.
    • (2007) Angew Chem Int Ed Engl , vol.46 , pp. 5880-5884
    • Maiti, K.K.1    Lee, W.S.2    Takeuchi, T.3    Watkins, C.4    Fretz, M.5    Kim, D.C.6
  • 6
    • 67349102019 scopus 로고    scopus 로고
    • Novel lipidated sorbitol-based molecular transporters for non-viral gene delivery
    • Higashi T., Khalil I.A., Maiti K.K., Lee W.S., Akita H., Harashima H., et al. Novel lipidated sorbitol-based molecular transporters for non-viral gene delivery. J Control Release 2009, 136:140-147.
    • (2009) J Control Release , vol.136 , pp. 140-147
    • Higashi, T.1    Khalil, I.A.2    Maiti, K.K.3    Lee, W.S.4    Akita, H.5    Harashima, H.6
  • 7
    • 2342595835 scopus 로고    scopus 로고
    • Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
    • Wadia J.S., Stan R.V., Dowdy S.F. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 2004, 10:310-315.
    • (2004) Nat Med , vol.10 , pp. 310-315
    • Wadia, J.S.1    Stan, R.V.2    Dowdy, S.F.3
  • 8
    • 0035902477 scopus 로고    scopus 로고
    • TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors
    • Torchilin V.P., Rammohan R., Weissig V., Levchenko T.S. TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors. Proc Natl Acad Sci USA 2001, 98:8786-8791.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8786-8791
    • Torchilin, V.P.1    Rammohan, R.2    Weissig, V.3    Levchenko, T.S.4
  • 9
    • 3242657221 scopus 로고    scopus 로고
    • Development of a non-viral multifunctional envelope-type nano device by a novel lipid film hydration method
    • Kogure K., Moriguchi R., Sasaki K., Ueno M., Futaki S., Harashima H. Development of a non-viral multifunctional envelope-type nano device by a novel lipid film hydration method. J Control Release 2004, 98:317-323.
    • (2004) J Control Release , vol.98 , pp. 317-323
    • Kogure, K.1    Moriguchi, R.2    Sasaki, K.3    Ueno, M.4    Futaki, S.5    Harashima, H.6
  • 10
    • 43049154835 scopus 로고    scopus 로고
    • Pentablock copolymers of poly(ethylene glycol), poly((2-dimethyl amino)ethyl methacrylate) and poly(2-hydroxyethyl methacrylate) from consecutive atom transfer radical polymerizations for non-viral gene delivery
    • Xu F.J., Li H., Li J., Zhang Z., Kang E.T., Neoh K.G. Pentablock copolymers of poly(ethylene glycol), poly((2-dimethyl amino)ethyl methacrylate) and poly(2-hydroxyethyl methacrylate) from consecutive atom transfer radical polymerizations for non-viral gene delivery. Biomaterials 2008, 29:3023-3033.
    • (2008) Biomaterials , vol.29 , pp. 3023-3033
    • Xu, F.J.1    Li, H.2    Li, J.3    Zhang, Z.4    Kang, E.T.5    Neoh, K.G.6
  • 11
    • 77955896428 scopus 로고    scopus 로고
    • Influence of hydroxyl groups on the biological properties of cationic polymethacrylates as gene vectors
    • Ma M., Li F., Yuan Z.F., Zhuo R.X. Influence of hydroxyl groups on the biological properties of cationic polymethacrylates as gene vectors. Acta Biomater 2010, 6:2658-2665.
    • (2010) Acta Biomater , vol.6 , pp. 2658-2665
    • Ma, M.1    Li, F.2    Yuan, Z.F.3    Zhuo, R.X.4
  • 12
    • 21744445582 scopus 로고    scopus 로고
    • Degradable polyethylenimine-alt-poly(ethylene glycol) copolymers as novel gene carriers
    • Park M.R., Han K.O., Han I.K., Cho M.H., Nah J.W., Choi Y.J., et al. Degradable polyethylenimine-alt-poly(ethylene glycol) copolymers as novel gene carriers. J Control Release 2005, 105:367-380.
    • (2005) J Control Release , vol.105 , pp. 367-380
    • Park, M.R.1    Han, K.O.2    Han, I.K.3    Cho, M.H.4    Nah, J.W.5    Choi, Y.J.6
  • 14
    • 0035408714 scopus 로고    scopus 로고
    • Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo
    • Wightman L., Kircheis R., Rössler V., Carotta S., Ruzicka R., Kursa M., et al. Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo. J Gene Med 2001, 3:362-372.
    • (2001) J Gene Med , vol.3 , pp. 362-372
    • Wightman, L.1    Kircheis, R.2    Rössler, V.3    Carotta, S.4    Ruzicka, R.5    Kursa, M.6
  • 15
    • 33646679654 scopus 로고    scopus 로고
    • Michael addition reactions in macromolecular design for emerging technologies
    • Mather B.D., Viswanathan K., Miller K.M., Long T.E. Michael addition reactions in macromolecular design for emerging technologies. Prog Polym Sci 2006, 31:487-531.
    • (2006) Prog Polym Sci , vol.31 , pp. 487-531
    • Mather, B.D.1    Viswanathan, K.2    Miller, K.M.3    Long, T.E.4
  • 16
    • 0034623567 scopus 로고    scopus 로고
    • Degradable poly (β-amino esters):synthesis, characterization, and self-Assembly with plasmid DNA
    • Lynn D.M., Langer R. Degradable poly (β-amino esters):synthesis, characterization, and self-Assembly with plasmid DNA. J Am Chem Soc 2000, 122:10761-10768.
    • (2000) J Am Chem Soc , vol.122 , pp. 10761-10768
    • Lynn, D.M.1    Langer, R.2
  • 17
    • 58149200165 scopus 로고    scopus 로고
    • Biodegradable poly (ester amine) based on glycerol dimethacrylate and polyethylenimine as a gene carrier
    • Arote R.B., Hwang S.K., Yoo M.K., Jere D., Jiang H.L., Kim Y.K., et al. Biodegradable poly (ester amine) based on glycerol dimethacrylate and polyethylenimine as a gene carrier. J Gene Med 2008, 10:1223-1235.
    • (2008) J Gene Med , vol.10 , pp. 1223-1235
    • Arote, R.B.1    Hwang, S.K.2    Yoo, M.K.3    Jere, D.4    Jiang, H.L.5    Kim, Y.K.6
  • 18
    • 33750465842 scopus 로고    scopus 로고
    • A biodegradable poly(ester amine) based on polycaprolactone and polyethylenimine as a gene carrier
    • Arote R., Kim T.H., Kim Y.K., Hwang S.K., Jiang H.L., Song H.H., et al. A biodegradable poly(ester amine) based on polycaprolactone and polyethylenimine as a gene carrier. Biomaterials 2007, 28:735-744.
    • (2007) Biomaterials , vol.28 , pp. 735-744
    • Arote, R.1    Kim, T.H.2    Kim, Y.K.3    Hwang, S.K.4    Jiang, H.L.5    Song, H.H.6
  • 19
    • 0141569730 scopus 로고    scopus 로고
    • A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery
    • Forrest M.L., Koerber J.T., Pack D.W. A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery. Bioconjug Chem 2003, 14:934-940.
    • (2003) Bioconjug Chem , vol.14 , pp. 934-940
    • Forrest, M.L.1    Koerber, J.T.2    Pack, D.W.3
  • 20
    • 0038004448 scopus 로고    scopus 로고
    • A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity
    • Fischer D., Bieber T., Li Y., Elsässer H.P., Kissel T. A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity. Pharm Res 1999, 16:1273-1279.
    • (1999) Pharm Res , vol.16 , pp. 1273-1279
    • Fischer, D.1    Bieber, T.2    Li, Y.3    Elsässer, H.P.4    Kissel, T.5
  • 23
    • 14844323981 scopus 로고    scopus 로고
    • Hydroxyl stereochemistry amine number within poly(glycoamidoamine)s affect intracellular DNA delivery
    • Liu Y., Reineke T.M. Hydroxyl stereochemistry amine number within poly(glycoamidoamine)s affect intracellular DNA delivery. J Am Chem Soc 2005, 127:3004-3015.
    • (2005) J Am Chem Soc , vol.127 , pp. 3004-3015
    • Liu, Y.1    Reineke, T.M.2
  • 24
    • 0029981092 scopus 로고    scopus 로고
    • Evidence for the role of proteoglycans in cation-mediated gene transfer
    • Mislick K.A., Baldeschwieler J.D. Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc Natl Acad Sci USA 1996, 93:12349-12354.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12349-12354
    • Mislick, K.A.1    Baldeschwieler, J.D.2
  • 25
    • 0032473410 scopus 로고    scopus 로고
    • Polylysine-based transfection systems utilizing receptor-mediated delivery
    • Wagner E., Ogris M., Zauner W. Polylysine-based transfection systems utilizing receptor-mediated delivery. Adv Drug Deliv Rev 1998, 30:97-113.
    • (1998) Adv Drug Deliv Rev , vol.30 , pp. 97-113
    • Wagner, E.1    Ogris, M.2    Zauner, W.3
  • 26
    • 33644627889 scopus 로고    scopus 로고
    • The expanding role of aerosols in systemic drug delivery, gene therapy, and vaccination
    • Laube B.L. The expanding role of aerosols in systemic drug delivery, gene therapy, and vaccination. Respir Care 2005, 50:1161-1176.
    • (2005) Respir Care , vol.50 , pp. 1161-1176
    • Laube, B.L.1
  • 27
    • 15944418284 scopus 로고    scopus 로고
    • The use of amino acids to enhance the aerosolisation of spray-dried powders for pulmonary gene therapy
    • Li H.Y., Seville P.C., Williamson I.J., Birchall J.C. The use of amino acids to enhance the aerosolisation of spray-dried powders for pulmonary gene therapy. J Gene Med 2005, 7:343-353.
    • (2005) J Gene Med , vol.7 , pp. 343-353
    • Li, H.Y.1    Seville, P.C.2    Williamson, I.J.3    Birchall, J.C.4
  • 28
    • 0036632415 scopus 로고    scopus 로고
    • Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying
    • Seville P.C., Kellaway I.W., Birchall J.C. Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying. J Gene Med 2002, 4:428-437.
    • (2002) J Gene Med , vol.4 , pp. 428-437
    • Seville, P.C.1    Kellaway, I.W.2    Birchall, J.C.3
  • 29
    • 33646892850 scopus 로고    scopus 로고
    • Chitosan-modified dry powder formulations for pulmonary gene delivery
    • Li H.Y., Birchall J. Chitosan-modified dry powder formulations for pulmonary gene delivery. Pharm Res 2006, 23:941-950.
    • (2006) Pharm Res , vol.23 , pp. 941-950
    • Li, H.Y.1    Birchall, J.2
  • 30
    • 0034821014 scopus 로고    scopus 로고
    • Accelerated discovery of synthetic transfection vectors: parallel synthesis and screening of a degradable polymer library
    • Lynn D.M., Anderson D.G., Putnam D., Langer R. Accelerated discovery of synthetic transfection vectors: parallel synthesis and screening of a degradable polymer library. Am Chem Soc 2001, 123:8155-8156.
    • (2001) Am Chem Soc , vol.123 , pp. 8155-8156
    • Lynn, D.M.1    Anderson, D.G.2    Putnam, D.3    Langer, R.4
  • 31
    • 0038293017 scopus 로고    scopus 로고
    • Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery
    • Akinc A., Lynn D.M., Anderson D.G., Langer R. Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery. J Am Chem Soc 2003, 125:5316-5323.
    • (2003) J Am Chem Soc , vol.125 , pp. 5316-5323
    • Akinc, A.1    Lynn, D.M.2    Anderson, D.G.3    Langer, R.4
  • 32
    • 0014217907 scopus 로고
    • A membrane effect of basic polymers dependent on molecular size
    • Ryser H.J. A membrane effect of basic polymers dependent on molecular size. Nature 1967, 215:934-936.
    • (1967) Nature , vol.215 , pp. 934-936
    • Ryser, H.J.1
  • 33
    • 0031005194 scopus 로고    scopus 로고
    • In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer
    • Goldman C.K., Soroceanu L., Smith N., Gillespie G.Y., Shaw W., Burgess S., et al. In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer. Nat Biotechnol 1997, 15:462-466.
    • (1997) Nat Biotechnol , vol.15 , pp. 462-466
    • Goldman, C.K.1    Soroceanu, L.2    Smith, N.3    Gillespie, G.Y.4    Shaw, W.5    Burgess, S.6
  • 34
    • 0035424424 scopus 로고    scopus 로고
    • In vitro gene delivery mediated by chitosan: effect of pH, serum, and molecular mass of chitosan on the transfection efficiency
    • Sato T., Ishii T., Okahata Y. In vitro gene delivery mediated by chitosan: effect of pH, serum, and molecular mass of chitosan on the transfection efficiency. Biomaterials 2001, 22:2075-2080.
    • (2001) Biomaterials , vol.22 , pp. 2075-2080
    • Sato, T.1    Ishii, T.2    Okahata, Y.3
  • 35
    • 0042856420 scopus 로고    scopus 로고
    • Biodistribution and pharmacokinetics of aerosol and intravenously administered DNA-polyethyleneimine complexes: optimization of pulmonary delivery and retention
    • Koshkina N.V., Agoulnik I.Y., Melton S.L., Densmore C.L., Knight V. Biodistribution and pharmacokinetics of aerosol and intravenously administered DNA-polyethyleneimine complexes: optimization of pulmonary delivery and retention. Mol Ther 2003, 8:249-254.
    • (2003) Mol Ther , vol.8 , pp. 249-254
    • Koshkina, N.V.1    Agoulnik, I.Y.2    Melton, S.L.3    Densmore, C.L.4    Knight, V.5
  • 36
    • 23844528337 scopus 로고    scopus 로고
    • Aerosolized nanogram quantities of plasmid DNA mediate highly efficient gene delivery to mouse airway epithelium
    • Rudolph C., Schillinger U., Ortiz A., Plank C., Golas M.M., Sander B., et al. Aerosolized nanogram quantities of plasmid DNA mediate highly efficient gene delivery to mouse airway epithelium. Mol Ther 2005, 12:493-501.
    • (2005) Mol Ther , vol.12 , pp. 493-501
    • Rudolph, C.1    Schillinger, U.2    Ortiz, A.3    Plank, C.4    Golas, M.M.5    Sander, B.6
  • 37
    • 0037805638 scopus 로고    scopus 로고
    • COX2 activity promotes organic osmolyte accumulation and adaptation of renal medullary interstitial cells to hypertonic stress
    • Moeckel G.W., Zhang L., Fogo A.B., Hao C.M., Pozzi A., Breyer M.D. COX2 activity promotes organic osmolyte accumulation and adaptation of renal medullary interstitial cells to hypertonic stress. J Biol Chem 2003, 278:19352-19357.
    • (2003) J Biol Chem , vol.278 , pp. 19352-19357
    • Moeckel, G.W.1    Zhang, L.2    Fogo, A.B.3    Hao, C.M.4    Pozzi, A.5    Breyer, M.D.6
  • 38
    • 0034725709 scopus 로고    scopus 로고
    • MAPK mediation of hypertonicity-stimulated cyclooxygenase-2 expression in renal medullary collecting duct cells
    • Yang T., Huang Y., Heasley L.E., Berl T., Schnermann J.B., Briggs J.P. MAPK mediation of hypertonicity-stimulated cyclooxygenase-2 expression in renal medullary collecting duct cells. J Biol Chem 2000, 275:23281-23286.
    • (2000) J Biol Chem , vol.275 , pp. 23281-23286
    • Yang, T.1    Huang, Y.2    Heasley, L.E.3    Berl, T.4    Schnermann, J.B.5    Briggs, J.P.6
  • 39
    • 72449156516 scopus 로고    scopus 로고
    • Efficient gene delivery with osmotically active and hyperbranched poly(ester amine)s
    • Arote R.B., Lee E.S., Jiang H.L., Kim Y.K., Choi Y.J., Cho M.H., et al. Efficient gene delivery with osmotically active and hyperbranched poly(ester amine)s. Bioconjug Chem 2009, 20:2231-2241.
    • (2009) Bioconjug Chem , vol.20 , pp. 2231-2241
    • Arote, R.B.1    Lee, E.S.2    Jiang, H.L.3    Kim, Y.K.4    Choi, Y.J.5    Cho, M.H.6
  • 40
    • 0033758920 scopus 로고    scopus 로고
    • Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs
    • Bragonzi A., Dina G., Villa A., Calori G., Biffi A., Bordignon C., et al. Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs. Gene Ther 2000, 7:1753-1760.
    • (2000) Gene Ther , vol.7 , pp. 1753-1760
    • Bragonzi, A.1    Dina, G.2    Villa, A.3    Calori, G.4    Biffi, A.5    Bordignon, C.6
  • 41
  • 42
    • 37149041435 scopus 로고    scopus 로고
    • Ectodomain shedding of pro-TGF-alpha is required for COX-2 induction and cell survival in renal medullary cells exposed to osmotic stress
    • Küper C., Bartels H., Fraek M.L., Beck F.X., Neuhofer W. Ectodomain shedding of pro-TGF-alpha is required for COX-2 induction and cell survival in renal medullary cells exposed to osmotic stress. Am J Physiol Cell Physiol 2007, 293:C1971-C1982.
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Küper, C.1    Bartels, H.2    Fraek, M.L.3    Beck, F.X.4    Neuhofer, W.5
  • 43
    • 66049119614 scopus 로고    scopus 로고
    • EGF receptor signaling is involved in expression of osmoprotective TonEBP target gene aldose reductase under hypertonic conditions
    • Küper C., Steinert D., Fraek M.L., Beck F.X., Neuhofer W. EGF receptor signaling is involved in expression of osmoprotective TonEBP target gene aldose reductase under hypertonic conditions. Am J Physiol Renal Physiol 2009, 296:F1100-F1108.
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Küper, C.1    Steinert, D.2    Fraek, M.L.3    Beck, F.X.4    Neuhofer, W.5
  • 44
    • 0038824812 scopus 로고    scopus 로고
    • Hypertonic induction of COX-2 expression in renal medullary epithelial cells requires transactivation of the EGFR
    • Zhao H., Tian W., Tai C., Cohen D.M. Hypertonic induction of COX-2 expression in renal medullary epithelial cells requires transactivation of the EGFR. Am J Physiol Renal Physiol 2003, 285:F281-F288.
    • (2003) Am J Physiol Renal Physiol , vol.285
    • Zhao, H.1    Tian, W.2    Tai, C.3    Cohen, D.M.4
  • 46
  • 47
    • 31144456365 scopus 로고    scopus 로고
    • Celecoxib leads to G2/M arrest by induction of p21 and down-regulation of cyclin B1 expression in a p53-independent manner
    • Dvory-Sobol H., Cohen-Noyman E., Kazanov D., Figer A., Birkenfeld S., Madar-Shapiro L., et al. Celecoxib leads to G2/M arrest by induction of p21 and down-regulation of cyclin B1 expression in a p53-independent manner. Eur J Cancer 2006, 42:422-426.
    • (2006) Eur J Cancer , vol.42 , pp. 422-426
    • Dvory-Sobol, H.1    Cohen-Noyman, E.2    Kazanov, D.3    Figer, A.4    Birkenfeld, S.5    Madar-Shapiro, L.6
  • 48
    • 61449211035 scopus 로고    scopus 로고
    • Lipopolysaccharide initiates a positive feedback of epidermal growth factor receptor signaling by prostaglandin E2 in human biliary carcinoma cells
    • Finzi L., Shao M.X., Paye F., Housset C., Nadel J.A. Lipopolysaccharide initiates a positive feedback of epidermal growth factor receptor signaling by prostaglandin E2 in human biliary carcinoma cells. J Immunol 2009, 182:2269-2276.
    • (2009) J Immunol , vol.182 , pp. 2269-2276
    • Finzi, L.1    Shao, M.X.2    Paye, F.3    Housset, C.4    Nadel, J.A.5
  • 50
    • 33749634668 scopus 로고    scopus 로고
    • Multiple glycerol shocks increase the calcium phosphate transfection of non-synchronized CHO cells
    • Grosjean F., Bertschinger M., Hacker D.L., Wurm F.M. Multiple glycerol shocks increase the calcium phosphate transfection of non-synchronized CHO cells. Biotechnol Lett 2006, 28:1827-1833.
    • (2006) Biotechnol Lett , vol.28 , pp. 1827-1833
    • Grosjean, F.1    Bertschinger, M.2    Hacker, D.L.3    Wurm, F.M.4
  • 51
    • 33745989813 scopus 로고    scopus 로고
    • Organic osmolyte channels in the renal medulla: their properties and regulation
    • Rolf K.H.K., Helmut K., Birgit R., Frank W., Stefan H.B., Evamaria K.S. Organic osmolyte channels in the renal medulla: their properties and regulation. Amer Zool 2001, 41:728-733.
    • (2001) Amer Zool , vol.41 , pp. 728-733
    • Rolf, K.H.K.1    Helmut, K.2    Birgit, R.3    Frank, W.4    Stefan, H.B.5    Evamaria, K.S.6


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