In Vitro and In Vivo Gene Delivery Mediated By A Synthetic Polycationic Amino Polymer

Nature Biotechnology

Volumn 15, Issue 5, 1997, Pages 462-466

  Goldman, Corey K ^b   Soroceanu, Lilians ^a   Smith, Natalie ^b   Gillespie, G Yancey ^a   Shaw, Walter ^b   Burgess, Steve ^b   Bilbao, Guadalupe ^b   Curiel, David T ^b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b Avanti Polar Lipids Inc   (United States)

Author keywords

Gene therapy; Gene transfer; Liposome; Transfection

Indexed keywords

LIPOSOME; POLYCATION; VIRUS VECTOR;

ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REPORTER GENE;

ANIMALS; BETA-GALACTOSIDASE; BIOCOMPATIBLE MATERIALS; BRAIN NEOPLASMS; CATION EXCHANGE RESINS; CELL SURVIVAL; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GLIOMA; GREEN FLUORESCENT PROTEINS; HUMANS; LIPIDS; LIPOSOMES; LUCIFERASES; LUMINESCENT PROTEINS; MICE; MICE, SCID; PLASMIDS; POLYAMINES; SARCOMA; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0031005194     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt0597-462     Document Type: Article

References (30)

1. Lemarchand, P., Jones, M., Yamada, I., and Crystal, R.G. 1993. In vivo gene transfer in normal uninjured blood vessels using replication-deficient recombinant adenoviral vectors. Circulation Res. 72:1132-1138.
2. Gao, X. and Huang, L. 1995. Cationic liposome-mediated gene delivery. Gene Therapy 2:710-722.
3. Feigner, P.L., Tsai, Y.J., Sukhu, L., Wheeler, C.J., Manthorpe, M., Marshall, J., et al. 1995. Improved cationic lipid formulations for in vivo gene therapy. [Review] Ann. N.Y. Acad. Sci. 772:126-139.
4. Mizuguchi, H., Nakagawa, T., Nakanishi, M., Imazu, S., Nakagawa, S., Mayumi, T. 1996. Efficient gene transfer into mammalian cells using fuso-genic liposome. Bio. Biophys. Res. Comm. 218:402-407.
5. Sawa, Y., Suzuki, K., Bai, H.Z., Shirakura, R., Morishita, R., Kaneda, Y., et al. 1995. Efficiency of in vivo gene transfection into transplanted rat heart by coronary infusion of HVJ liposome. Circulation 92(9 Suppl):M479-M482.
6. Solodin, I., Brown, C.S., Bruno, M.S., Chow, C.Y., Jang, E.H., Debs, R.J., et al. 1995. A novel series of amphiphilic imidazolinium compounds for in vitro and in vivo gene delivery. Biochemistry 34:13537-13544.
7. Ooboshi, H., Welsh, M.J., Rios, CD., Davidson, B.L., and Heistad, D.D. 1995. Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue. Circulation Res. 77:7-13.
8. Boussif, O., Lezoualc’h, F, Zanta, M.A., Mergny, M.D., Scherman, D., Demeneix, B., et al. 1995. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl. Acad. Sci. USA 92:7297-7301.
9. Cook, D.R., Maxwell, I.H., Glode, L.M., Maxwell, F., Stevens, J.O., Purner, M.B., et al. 1994. Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate. Cancer Biotherapy 9:131-141.
10. Nabel, E.G., Gordon, D., Yang, Z.Y., Xu, L, San, H., Plautz, G.E., et al. 1992. Gene transfer in vivo with DNA-liposome complexes: lack of autoimmunity and gonadal localization. Hum. Gene Ther. 3:649-656.
11. Hoeben, R.C., Fallaux, F.J., Van Tilburg, N.H., Cramer, S.J., Van Ormondt, H., Briet, E., et al. 1993. Toward gene therapy for hemophilia A: long-term persistence of factor VIII-secreting fibroblasts after transplantation into immunodeficient mice. Hum. Gene Ther. 4:179-186.
12. Hanania, E.G., Kavanagh, J., Hortobagyi, G., Giles, R.E., Champlim, R., Deisseroth, A.B. 1995. Recent advances in the application of gene therapy to human disease. [Review] Amer. J. Med. 99:537-552.
13. Thierry, A.R., Lunardi-lskandar, Y, Bryant, J.L., Rabinovich, P., Gallo, R.C., and Mahan, L.C. 1995. Systemic gene delivery: biodistribution and long-term expression of a transgene in mice. Proc. Natl. Acad. Sci. USA 92:9742-9746.
14. Schofield, J.P. and Caskey, C.T. 1995. Non-viral approaches to gene therapy. [Review] Br. Med. Bull. 51:56-71.
15. Blasese, M., Blankenstein, T, Brenner, M., Cohen-Haguenauer, O., Gasnsbacher, B., Russel, S., et al. Vectors in cancer therapy: how will they deliver? Cancer Gene Ther. 2;4:291-297.
16. Cao, L, Zheng, Z.C., Zhao, Y.C., Jiang, Z.H., Liu, Z.G., Chen, S.D., et al. 1995. Gene therapy of Parkinson disease model rat by direct injection of plasmid DNA-lipofectin complex. Hum. Gene Ther. 6:1497-1501.
17. Yagi, K., Hayashi, Y., Ishida, N., Ohbayashi, M., Ohishi, N., Mizuno, M., et al. 1994. Interferon-beta endogenously produced by intratumoral injection of cationic liposome-encapsulated gene: cytocidal effect on glioma transplanted into nude mouse brain. Biochem. Mol. Biol. Int. 32:167-171.
18. Roessler, B.J. and Davidson, B.L. 1994. Direct plasmid mediated transfection of adult murine brain cells in vivo using cationic liposomes. Neurosci. Let. 167:5-10.
19. Uutz, J., Augustin, A.J., Jager, L.J., Bachmann, D., and Brandl, M. 1995. Acute toxicity and depression of phagocytosis in vivo by liposomes: influence of lysophosphatidylcholine. Life Sci. 56:99-106.
20. Sambrook, J., Fritsch, E.F., and Maniatis, T. 1989. Molecular cloning. 2nd ed. Chapter 6, 6.2-6.13. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
21. Cubitt, A.B., Heim, R., Adams, S.R., Boyd, A.E., Gross, L.A., and Tsien, R.Y. 1995. Understanding, improving and using green fluorescent proteins. [Review] Trends Biochem. Sci. 20:448-455.
22. Teramoto, S., Johnson, L.G., Huang, W., Leigh, M.W., and Boucher, R.C. 1995. Effect of adenoviral vector infection on cell proliferation in cultured primary human airway epithelial cells. Hum. Gene Ther. 6:1045-1053.
23. Vincent, M.C., Trapnell, B.C., Baughman, R.P., Wert, S.E., Whitsett, J.A., and Iwamoto, H.S. 1995. Adenovirus-mediated gene transfer to the respiratory tract of fetal sheep in utero. Hum. Gene Ther. 6:1019-1028.
24. Bass, C, Cabrera, G., Elgavish, A., Robert, B., Siegal, G.P., Anderson, S.C., et al. 1995. Recombinant adenovirus-mediated gene transfer to genitourinary epithelium in vitro and in vivo. Cancer Gene Ther. 2:97-104.
25. Lozier, J.N., Thompson, A.R., Hu, PC, Read, M., Brinkhous, K.M., et al. 1994. Efficient transfection of primary cells in a canine hemophilia B model using adenovirus-polylysine-DNA complexes. Hum. Gene Ther. 5:313-322.
26. Muldoon, E.G., Nilaver, G., Kroll, R.A., Pagel, M.A., Breakenfield, X.O., Chiocca, E.A., et al. 1995. Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain. Amer. J. Pathol. 147:1840-1851.
27. Enomaa, N., Danos, O., Peltonen, L., and Jalanko, A. 1995. Correction of deficient enzyme activity in a lysosomal storage disease, aspartylglu-cosaminuria, by enzyme replacement and retroviral gene transfer. Hum. Gene Ther. 6:723-731.
28. Szilvassy, S.J. and Cory, S. 1994. Efficient retroviral gene transfer to purified long-term repopulating hematopoietic stem cells. Blood 84:74-83.
29. Byrnes, A.R, Rusby, J.E., Wood, M.J., and Charlton, H.M. 1995. Adenovirus gene transfer causes inflammation in the brain. Neuroscience 66:1015-1024.
30. Graham, F. and Prevec, L. 1991. Manipulation of adenovirus vectors, pp. 109-129 in Methods in molecular biology Vol 7, Gene Transfer and expression techniques. Murray, E.J. and Walker, J.M. (eds.). Humana Press, Clifton, NJ.