Dicaffeoylquinic acids in Yerba mate (Ilex paraguariensis St. Hilaire) inhibit NF-κB nucleus translocation in macrophages and induce apoptosis by activating caspases-8 and -3 in human colon cancer cells

Molecular Nutrition and Food Research

Volumn 55, Issue 10, 2011, Pages 1509-1522

  Puangpraphant, Sirima ^a   Berhow, Mark A ^b   Vermillion, Karl ^b   Potts, Greg ^a   Gonzalez de Mejia, Elvira ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Apoptosis; Colon cancer; Dicaffeoylquinic acids; Inflammation; Yerba mate

Indexed keywords

3,4 DI O CAFFEOYLQUINIC ACID; 3,4-DI-O-CAFFEOYLQUINIC ACID; 3,5-DICAFFEOYLQUINIC ACID; ANTINEOPLASTIC AGENT; BAX PROTEIN, HUMAN; CASPASE 3; CASPASE 8; CHLOROGENIC ACID; CYCLOOXYGENASE 2; DRUG DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOCHLOROGENIC ACID; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PLANT EXTRACT; PROSTAGLANDIN E2; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CELL STRAIN HT29; CHEMISTRY; COLON TUMOR; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVATION; HUMAN; ILEX PARAGUARIENSIS; ISOLATION AND PURIFICATION; MACROPHAGE; METABOLISM; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; PLANT LEAF; PROTEIN TRANSPORT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 8; CELL NUCLEUS; CELL PROLIFERATION; CHLOROGENIC ACID; COLONIC NEOPLASMS; CYCLOOXYGENASE 2; DINOPROSTONE; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; HT29 CELLS; HUMANS; ILEX PARAGUARIENSIS; LIPOPOLYSACCHARIDES; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PLANT LEAVES; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2;

CROTON OVALIFOLIUS; ILEX PARAGUARIENSIS;

EID: 80053919500     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201100128     Document Type: Article

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