Water extract of propolis and its main constituents, caffeoylquinic acid derivatives, exert neuroprotective effects via antioxidant actions

Life Sciences

Volumn 80, Issue 4, 2007, Pages 370-377

  Nakajima, Yoshimi ^a   Shimazawa, Masamitsu ^a   Mishima, Satoshi ^b   Hara, Hideaki ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b Api Company Ltd   (Japan)

Author keywords

Caffeoylquinic acid; Glutamate; Oxidative stress; Propolis; Retinal ganglion cell

Indexed keywords

3,4 DI O CAFFEOYLQUINIC ACID; 3,5 DI O CAFFEOYLQUINIC ACID; ARTEPILLIN C; BACCHARIN; BUTHIONINE SULFOXIMINE; CHLOROGENIC ACID; CINNAMIC ACID DERIVATIVE; CYSTINE; DRUPANIN; GLUTAMIC ACID; GLUTATHIONE; PARA COUMARIC ACID; PROPOLIS; QUINIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN HOMOGENATE; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; FOREBRAIN; LIPID PEROXIDATION; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT; RETINA GANGLION CELL; RETINA INJURY; STRUCTURE ANALYSIS;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTIOXIDANTS; CELL LINE; CELL SURVIVAL; CINNAMATES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; GLUTAMIC ACID; LIPID PEROXIDATION; MALE; MICE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PROPOLIS; PROSENCEPHALON; QUINIC ACID; RATS; RETINAL GANGLION CELLS; WATER;

RATTUS;

EID: 33845670452     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.09.017     Document Type: Article

References (37)

1. Bankova V., Marcucci M.C., Simova S., Nikolova N., Kujumgiev A., and Popov S. Antibacterial diterpenic acids from Brazilian propolis. Zeitschrift fur Naturforschung. C, A Journal of Biosciences 51 5-6 (1996) 277-280
2. Bankova V.S., de Castro S.L., and Marcucci M.C. Propolis: recent advances in chemistry and plant origin. Apidologie 31 (2000) 3-15
3. Basnet P., Matsushige K., Hase K., Kadota S., and Namba T. Four di-O-caffeoyl quinic acid derivatives from propolis. Potent hepatoprotective activity in experimental liver injury models. Biological & Pharmaceutical Bulletin 19 11 (1996) 1479-1484
4. Bonfoco E., Krainc D., Ankarcrona M., Nicotera P., and Lipton S.A. Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-d-aspartate or nitric oxide/superoxide in cortical cell cultures. Proceedings of the National Academy of Sciences of the United States of America 92 16 (1995) 7162-7166
5. Bonne C., Muller A., and Villain M. Free radicals in retinal ischemia. General Pharmacology 30 3 (1998) 275-280
6. Chen C.N., Weng M.S., Wu C.L., and Lin J.K. Comparison of radical scavenging activity, cytotoxic effects and apoptosis induction in human melanoma cells by Taiwanese propolis from different sources. Evidence-based Complementary and Alternative Medicine 1 2 (2004) 175-185
7. Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1 8 (1988) 623-634
8. Coyle J.T., and Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 262 5134 (1993) 689-695
9. Drago L., Mombelli B., de Vecchi E., Fassina M.C., Tocalli L., and Gismondo M.R. In vitro antimicrobial activity of propolis dry extract. Journal of Chemotherapy 12 5 (2000) 390-395
10. Dreyer E.B. A proposed role for excitotoxicity in glaucoma. Journal of Glaucoma 7 1 (1998) 62-67
11. Haefliger I.O., Lietz A., Griesser S.M., Ulrich A., Schotzau A., Hendrickson P., and Flammer J. Modulation of Heidelberg retinal flowmeter parameter flow at the papilla of healthy subjects: effect of carbogen, oxygen, high intraocular pressure, and beta-blockers. Survey of Ophthalmology 43 Suppl 1 (1999) S59-S65
12. Han D., Sen C.K., Roy S., Kobayashi M.S., Tritschler H.J., and Packer L. Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants. American Journal of Physiology 273 5 Pt 2 (1997) R1771-R1778
13. Hara H., and Kogure K. Prevention of hippocampus neuronal damage in ischemic gerbils by a novel lipid peroxidation inhibitor (quinazoline derivative). Journal of Pharmacology and Experimental Therapeutics 255 2 (1990) 906-913
14. Ichikawa H., Satoh K., Tobe T., Yasuda I., Ushio F., Matsumoto K., Endo K., and Ookubo C. Free radical scavenging activity of propolis. Redox Report: Communications in Free Radical Research 7 5 (2002) 347-350
15. Inokuchi Y., Shimazawa M., Nakajima Y., Suemori S., Mishima S., and Hara H. Brazilian green propolis protects against retinal damage in vitro and in vivo. Evidence-based Complementary and Alternative Medicine 3 1 (2006) 71-77
16. Kim S.S., Park R.Y., Jeon H.J., Kwon Y.S., and Chun W. Neuroprotective effects of 3,5-dicaffeoylquinic acid on hydrogen peroxide-induced cell death in SH-SY5Y cells. Phytotherapy Research 19 3 (2005) 243-245
17. Krol W., Czuba Z., Scheller S., Gabrys J., Grabiec S., and Shani J. Anti-oxidant property of ethanolic extract of propolis (EEP) as evaluated by inhibiting the chemiluminescence oxidation of luminol. Biochemistry International 21 4 (1990) 593-597
18. Kumazawa S., Yoneda M., and Nakayama T. Constituents in Brazilian propolis and its plant of origin. Foods and Food Ingredients Journal of Japan 209 2 (2004) 132-139
19. Matsui T., Ebuchi S., Fujise T., Abesundara K.J., Doi S., Yamada H., and Matsumoto K. Strong antihyperglycemic effects of water-soluble fraction of Brazilian propolis and its bioactive constituent, 3, 4, 5-tri-O-caffeoylquinic acid. Biological & Pharmaceutical Bulletin 27 11 (2004) 1797-1803
20. Matsno T. Isolation and characterization of the tumoricidal substance from Brazilian propolis. Honeybee Science 13 (1992) 49-54
21. Matsushige K., Basnet P., Kadota S., and Namna T. Potent free radical scavenging activity of dicaffeoylquinic acid derivatives from propolis. Journal of Traditional Medicines 13 (1996) 217-228
22. Marcucci M.C. Propolis: chemical composition, biological properties and therapeutic activity. Apidologie 26 (1995) 83-99
23. McKinnon S.J. Glaucoma, apoptosis, and neuroprotection. Current Opinion in Ophthalmology 8 2 (1997) 28-37
24. Meldrum B., and Garthwaite J. Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends in Pharmacological Science 11 9 (1990) 379-387
25. Mishima S., Narita Y., Chikamatsu S., Inoh Y., Ohta S., Yoshida C., Araki Y., Akao Y., Suzuki K.M., and Nozawa Y. Effects of propolis on cell growth and gene expression in HL-60 cells. Journal of Ethnopharmacology 99 1 (2005) 5-11
26. Miyataka H., Nishiki M., Matsumoto H., Fujimoto T., Matsuka M., and Satoh T. Evaluation of propolis. I. Evaluation of Brazilian and Chinese propolis by enzymatic and physico-chemical methods. Biological & Pharmaceutical Bulletin 20 5 (1997) 496-501
27. Mirzoeva O.K., and Calder P.C. The effect of propolis and its components on eicosanoid production during the inflammatory response, prostaglandins. Leukotrienes and Essential Fatty Acids 55 6 (1996) 441-449
28. Monaghan D.T., Bridges R.J., and Cotman C.W. The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system. Annual Review of Pharmacology and Toxicology 29 (1989) 365-402
29. Murphy T.H., Miyamoto M., Sastre A., Schnaar R.L., and Coyle J.T. Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2 6 (1989) 1547-1558
30. Naito M., Umegaki H., and Iguchi A. Protective effects of probucol against glutamate-induced cytotoxicity in neuronal cell line PC12. Neuroscience Letters 186 2-3 (1995) 211-213
31. Neufeld A.H. Nitric oxide: a potential mediator of retinal ganglion cell damage in glaucoma. Survey of Ophthalmology 43 Suppl 1 (1999) S129-S135
32. Pamela M., and Anne H. Flavonoids protect retinal ganglion cells from oxidative stress-induced death. Investigative Ophthalmology and Visual Science 46 12 (2005) 4796-4803
33. Pereira C.M., and Oliveira C.R. Glutamate toxicity in a PC12 cell line involves glutathione (GSH) depletion and oxidative stress. Free Radical Biology and Medicine 23 4 (1997) 637-647
34. Scheller S., Wilczok T., Imielski S., Krol W., Gabrys J., and Shani J. Free radical scavenging by ethanol extract of propolis. International Journal of Radiation Biology 57 3 (1990) 461-465
35. Shimazawa M., Chikamatsu S., Morimoto N., Mishima S., Nagai H., and Hara H. Neuroprotection by Brazilian green propolis against in vitro and in vivo ischemic neuronal damage. Evidence-based Complementary and Alternative Medicine 2 2 (2005) 201-207
36. Shimazawa M., Yamashima T., Afarwal N., and Hara H. Neuroprotective effects of minocycline against in vitro and in vivo retinal cell damage. Brain Research 1053 1-2 (2005) 185-194
37. White M.J., DiCaprio M.J., and Greenberg D.A. Assessment of neuronal viability with Alamar blue in cortical and granule cell cultures. Journal of Neuroscience Methods 70 2 (1996) 195-200