Syncytial fusion of human trophoblast depends on caspase 8

Cell Death and Differentiation

Volumn 11, Issue 1, 2004, Pages 90-98

  Black, S ^a   Kadyrov, M ^a   Kaufmann, P ^a   Ugele, B ^b   Emans, N ^c   Huppertz, B ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Apoptosis; Caspase 8; Differentiation; Human placenta; Syncytial fusion; Villous trophoblast

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CASPASE 8; ORGANIC ANION TRANSPORTER; PROTEIN INHIBITOR;

CELL DIFFERENTIATION; CELL FUSION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTROPHOBLAST; ENZYME ACTIVITY; ENZYME REPRESSION; EXPLANT; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INCUBATION TIME; PLACENTA VILLUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SYNCYTIOTROPHOBLAST; SYNCYTIUM; TROPHOBLAST; WESTERN BLOTTING;

APOPTOSIS; CASPASE 8; CASPASES; CELL DIFFERENTIATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KERATINS; OLIGONUCLEOTIDES, ANTISENSE; PEPTIDES; PREGNANCY; TROPHOBLASTS;

MAMMALIA;

EID: 1642433091     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401307     Document Type: Review

References (58)

1. Benirschke K and Kaufmann P (2000) Pathology of the human placenta 4th edn (New York: Springer)
2. Pennica D, Nedwin GE, Hayflick JS, Seeburg PH, Derynck R, Palladino MA, Kohr WJ, Aggarwal BB and Goeddel DV (1984) Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature 312: 724-729
3. Yonehara S, Ishii A and Yonehara M (1989) A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J. Exp. Med. 169: 1747-1756
4. Trauth BC, Klas C, Peters AM, Matzku S, Moller P, Falk W, Debatin KM and Krammer PH (1989) Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245: 301-305
5. Kischkel FC, Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer PH and Peter ME (1995) Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14: 5579-5588
6. Lavrik I, Krueger A, Schmitz I, Baumann S, Weyd H, Krammer PH and Kirchhoff S (2003) The active caspase-8 heterotetramer is formed at the CD95 DISC. Cell Death Differ. 10: 144-145
7. Yui J, Garcia-Lloret M, Wegmann TG and Guilbert LJ (1994) Cytotoxicity of tumour necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts. Placenta 15: 819-835
8. Phillips TA, Ni J and Hunt JS (2001) Death-inducing tumour necrosis factor (TNF) superfamily ligands and receptors are transcribed in human placentae, cytotrophoblasts, placental macrophages and placental cell lines. Placenta 22: 663-672
9. LeBrun DP, Warnke RA and Cleary ML (1993) Expression of bcl-2 in fetal tissues suggests a role in morphogenesis. Am. J. Pathol. 142: 743-753
10. Huppertz B, Frank HG, Kingdom JCP, Reister F and Kaufmann P (1998) Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta. Histochem. Cell Biol. 110: 495-508
11. Suzuki A, Umezawa A, Sano M, Nozawa S and Hata J (2000) Involvement of EAT/mcl-1, a bcl-2 related gene, in the apoptotic mechanisms underlying human placental development and maintenance. Placenta 21: 177-183
12. Huppertz B, Frank HG, Reister F, Kingdom J, Korr H and Kaufmann P (1999) Apoptosis cascade progresses during turnover of human trophoblast: analysis of villous cytotrophoblast and syncytial fragments in vitro. Lab. Invest. 79: 1687-1702
13. Yusuf K, Smith SD, Sadovsky Y and Nelson DM (2002) Trophoblast differentiation modulates the activity of caspases in primary cultures of term human trophoblasts. Pediatr. Res. 52: 411-415
14. Ishizaki Y, Jacobson MD and Raff MC (1998) A role for caspases in lens fiber differentiation. J. Cell Biol. 140: 153-158
15. Morioka K, Tone S, Mukaida M and Takano-Ohmuro H (1998) The apoptotic and nonapoptotic nature of the terminal differentiation of erythroid cells. Exp. Cell Res. 240: 206-217
16. Weil M, Raff MC and Braga VM (1999) Caspase activation in the terminal differentiation of human epidermal keratinocytes. Curr. Biol. 9: 361-364
17. Eckhart L, Declercq W, Ban J, Rendl M, Lengauer B, Mayor C, Lippens S, Vandenabeele P and Tschachler E (2000) Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation. J. Invest. Dermatol. 115: 1148-1151
18. Lippens S, Kockx M, Knaapen M, Mortier L, Polakowska R, Verheyen A, Garmyn M, Zwijsen A, Formstecher P, Huylebroeck D, Vandenabeele P and Declercq W (2000) Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing. Cell Death Differ. 7: 1218-1224
19. Chien AJ, Presland RB and Kuechle MK (2002) Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation. Biochem. Biophys. Res. Commun. 296: 911-917
20. Martin SJ, O'Brien GA, Nishioka WK, McGahon AJ, Mahboubi A, Saido TC and Green DR (1995) Proteolysis of fodrin (non-erythroid spectrin) during apoptosis. J. Biol. Chem. 270: 6425-6428
21. Greidinger EL, Miller DK, Yamin TT, Casciola-Rosen L and Rosen A (1996) Sequential activation of three distinct ICE-like activities in Fas-ligated Jurkat cells. FEBS Left. 390: 299-303
22. Adler RR, Ng AK and Rote NS (1995) Monoclonal antiphosphatidylserine antibody inhibits intercellular fusion of the choriocarcinoma line, JAR. Biol. Reprod. 53: 905-910
23. Vogt E, Ng AK and Rote NS (1997) Antiphosphatidylserine antibody removes annexin-V and facilitates the binding of prothrombin at the surface of a choriocarcinoma model of trophoblast differentiation. Am. J. Obstet. Gynecol. 177: 964-972
24. Rohn TT, Rissman RA, Davis MC, Kim YE, Cotman CW and Head E (2002) Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain. Neurobiol. Dis. 11: 341-354
25. Issa Y, Wafts DC, Duxbury AJ, Brunton PA, Watson MB and Waters CM (2003) Mercuric chloride: toxicity and apoptosis in a human oligodendroglial cell line MO3.13. Biomaterials 24: 981-987
26. Vanden Hoek TL, Qin Y, Wojcik K, Li CQ, Shao ZH, Anderson T, Becker LB and Hamann KJ (2003) Reperfusion, not simulated ischemia, initiates intrinsic apoptosis injury in chick cardiomyocytes. Am. J. Physiol. Heart Circ. Physiol. 284: H141-H150
27. McArthur C, Wang Y, Veno P, Zhang J and Fiorella R (2002) Intracellular trafficking and surface expression of SS-A (Ro), SS-B (La), poly(ADP-ribose) polymerase and alpha-fodrin autoantigens during apoptosis in human salivary gland cells induced by tumour necrosis factor-alpha. Arch. Oral Biol. 47: 443-448
28. Berg CP, Engels IH, Rothbart A, Lauber K, Renz A, Schlosser SF, Schulze-Osthoff K and Wesselborg S (2001) Human mature red blood cells express caspase-3 and caspase-8, but are devoid of mitochondrial regulators of apoptosis. Cell Death Differ. 8: 1197-1206
29. Ugele R, St.Pierre MV, Pihusch M, Bahn A and Hantschmann P (2003) Characterization and identification of steroid sulphate transporters of human placenta. Am. J. Physiol. Endocrinol. Metab. 284: E390-E398
30. Caulin C, Salvesen GS and Oshima RG (1997) Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelia] cell apoptosis. J. Cell Biol. 138: 1379-1394
31. MacFarlane M, Merrison W, Dinsdale D and Cohen GM (2000) Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis. J. Cell Biol. 148: 1239-1254
32. Castellucci M, Kaufmann P and Bischof P (1990) Extracellular matrix influences hormone and protein production by human chorionic villi. Cell Tissue Res. 262: 135-142
33. Begum-Hasan J, Senterman M, Gillett P, LaPlante Branchaud C and Murphy BE (1993) Effect of maternal serum on Viability and function of early human placental explants. In Vitro Cell Dev. Biol. Anim. 29A: 505-511
34. Lappas M, Munns MJ, King RG and Rice GE (2001) Antisense oligonucleotide inhibition of type II phospholipase A2 expression, release and activity in vitro. Placenta 22: 418-424
35. Guilbert LJ, Winkler-Lowen B, Sherburne R, Rote NS, Li H and Morrish DW (2002) Preparation and functional characterization of villous cytotrophoblasts free of syncytial fragments. Placenta 23: 175-183
36. Shoeman RL, Hartig R, Huang Y, Grub S and Traub P (1997) Fluorescence microscopic comparison of the binding of phosphodiester and phosphorothioate (antisense) oligodeoxyribonucleotides to subcellular structures, including intermediate filaments, the endoplasmic reticulum, and the nuclear interior. Antisense Nucleic Acid Drug Dev. 7: 291-308
37. Pistritto G, Jost M, Srinivasula SM, Baffa R, Poyet JL, Karl C, Lazebnik Y, Rodeck U and Alnemri ES (2002) Expression and transcriptional regulation of caspase-14 in simple and complex epithelia. Cell Death Differ. 9: 995-1006
38. Nicholson DW and Thornberry NA (1997) Caspases: killer proteases. Trends Biochem. Sci. 22: 299-306
39. Salvesen GS and Dixit VM (1997) Caspases: intracellular signaling by proteolysis. Cell 91: 443-446
40. Sanders EJ and Parker E (2002) The role of mitochondria, cytochrome c and caspase-9 in embryonic lens fibre cell denucleation. J. Anat. 201: 121-135
41. Zou H, Li Y, Liu X and Wang X (1999) An APAF-1-cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274: 11549-11556
42. Fernandes-Alnemri T, Armstrong RC, Krebs J, Srinivasula SM, Wang L, Bullrich F, Fritz LC, Trapani JA, Tomaselli KJ, Litwack G and Alnemri ES (1996) In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc. Natl. Acad. Sci. USA 93: 7464-7469
43. Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME and Dixit VM (1996) FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85: 817-827
44. Eckhart L, Henry M, Santos-Beneit AM, Schmitz I, Krueger A, Fischer H, Bach J, Ban J, Kirchhoff S, Krammer PH, Mollinedo F and Tschachler E (2001) Alternative splicing of caspase-8 mRNA during differentiation of human leukocytes. Biochem. Biophys. Res. Commun. 289: 777-781
45. Secchiero P, Gonelli A, Mirandola P, Melloni E, Zamai L, Celeghini C, Milani D and Zauli G (2002) Tumor necrosis factor-related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway. Blood 100: 2421-2429
46. Huppertz B, Frank HG and Kaufmann P (1999) The apoptosis cascade - morphological and immunohistochemical methods for its visualization. Anat. Embryol. 200: 1-18
47. Jaenicke RU, Ng P, Sprengart ML and Porter AG (1998) Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis. J. Biol. Chem. 273: 15540-15545
48. Chen X, Wan Y, Bai Q, Zhang W and Zhu H (2002) Sodium salicylate-triggered apoptosis in HL-60 cells depends on caspase-8 activation. Int. J. Hematol.75: 407-411
49. Ferraro-Peyret C, Quemeneur L, Flacher M, Revillard JP and Genestier L (2002) Caspase-independent phosphatidylserine exposure during apoptosis of primary T lymphocytes. J. Immunol. 169: 4805-4810
50. Wolfsberg TG and White JM (1996) ADAMs in fertilization and development. Dev. Biol. 180: 389-401
51. LaBranche CC, Galasso G, Moore JP, Bolognesi DP, Hirsch MS and Hammer SM (2001) HIV fusion and its inhibition. Antiviral Res. 50: 95-115
52. Huppertz B, Tews DS and Kaufmann P (2001) Apoptosis and syncytial fusion in human placental trophoblast and skeletal muscle. Int. Rev. Cytol. 205: 215-253
53. Dedieu S, Dourdin N, Dargelos E, Poussard S, Veschambre P, Coffin P and Brustis JJ (2002) Calpain and myogenesis: development of a convenient cell culture model. Biol. Cell 94: 65-76
54. Wang KK (2000) Calpain and caspase: can you tell the difference? Trends Neurosci. 23: 20-26
55. Berg CP, Engels IH, Rothbart A, Lauber K, Renz A, Schlosser SF, Schulze-Osthoff K and Wesselborg S (2001) Human mature red blood cells express caspase-3 and caspase-8, but are devoid of mitochondrial regulators of apoptosis. Cell Death Differ. 8: 1197-1206
56. Formigli L, Papucci L, Tani A, Schiavone N, Tempestini A, Orlandini GE, Capaccioli S and Odandini SZ (2000) Aponecrosis: morphological and biochemical exploration of a syncretic process of cell death sharing apoptosis and necrosis. J. Cell Physiol. 182: 41-49
57. Fernandes-Alnemri T, Litwack G and Alnemri ES (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein CED-3 and mammalian interleukin-1-beta-converting enzyme. J. Biol. Chem. 269: 30761-30764
58. Kadyrov M, Kaufmann P and Huppertz B (2001) Expression of a cytokeratin 18 neo-epitope is a specific marker for trophoblast apoptosis in human placenta. Placenta 22: 44-48