Discovery of novel selective serotonin reuptake inhibitors through development of a protein-based pharmacophore

Journal of Chemical Information and Modeling

Volumn 51, Issue 9, 2011, Pages 2417-2426

  Manepalli, Sankar ^a   Geffert, Laura M ^a   Surratt, Christopher K ^a   Madura, Jeffry D ^a  

^a DUQUESNE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATION THEORY; COMPUTATIONAL METHODS; DIGITAL LIBRARIES; LEAD COMPOUNDS; NEUROPHYSIOLOGY; PHARMACODYNAMICS;

COMPUTATIONAL MODEL; HIGH RESOLUTION CRYSTAL STRUCTURE; RAY COORDINATES; SELECTIVE SEROTONIN RE-UPTAKE INHIBITORS; SEROTONIN TRANSPORTERS; SMALL MOLECULES; STRUCTURE-BASED; VIRTUAL SCREENING;

CRYSTAL STRUCTURE;

PROTEIN; SEROTONIN UPTAKE INHIBITOR;

ARTICLE; CHEMISTRY; DRUG DEVELOPMENT; HOMEOSTASIS; MOLECULAR LIBRARY;

DRUG DISCOVERY; HOMEOSTASIS; PROTEINS; SEROTONIN UPTAKE INHIBITORS; SMALL MOLECULE LIBRARIES;

EID: 80053295985     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci200280m     Document Type: Article

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