Quantitative structure-activity relationships of phenyltropanes as inhibitors of three monoamine transporters: Classical and CoMFA studies

Quantitative Structure-Activity Relationships

Volumn 18, Issue 4, 1999, Pages 342-353

  Muszynski, Inge C ^a   Scapozza, Leonardo ^b   Kovar, Karl Artur ^a   Folkers, Gerd ^b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b ETH ZURICH   (Switzerland)

Author keywords

2D QSAR; CoMFA; Free Wilson analysis; Monoamine transporter; Phenyltropanes; PLS

Indexed keywords

COMPUTATIONAL CHEMISTRY; ION EXCHANGE; QUANTUM THEORY; SODIUM; STATISTICAL METHODS;

2D QSAR; COMFA; CROSS VALIDATION; FREE-WILSON ANALYSE; INHIBITORY ACTIVITY; LEAVE ONE OUT; MONOAMINE TRANSPORTER; PHENYLTROPANE; PLS; QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP;

BINDING ENERGY;

CARRIER PROTEIN; DOPAMINE TRANSPORTER; HYDROGEN; METHYL GROUP; MONOAMINE; NORADRENALIN; PHENYLTROPANE; SEROTONIN TRANSPORTER; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTUM MECHANICS; STRUCTURE ACTIVITY RELATION;

EID: 0032701926     PISSN: 09318771     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3838(199910)18:4<342::AID-QSAR342>3.0.CO;2-E     Document Type: Article

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