Sinomenine protects against ischaemic brain injury: Involvement of co-inhibition of acid-sensing ion channel 1a and L-type calcium channels

British Journal of Pharmacology

Volumn 164, Issue 5, 2011, Pages 1445-1459

  Wu, Wen Ning ^a   Wu, Peng Fei ^a   Chen, Xiang Long ^a,d   Zhang, Zui ^a   Gu, Jun ^a   Yang, Yuan Jian ^a   Xiong, Qiu Ju ^a   Ni, Lan ^a   Wang, Fang ^a,b,c   Chen, Jian Guo ^a,b,c  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

acid sensing ion channels; middle cerebral artery occlusion; sinomenine; voltage gated calcium channels

Indexed keywords

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1A; CALCIUM; CALCIUM CHANNEL L TYPE; SINOMENINE; UNCLASSIFIED DRUG;

ACIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN INFARCTION; BRAIN ISCHEMIA; CALCIUM CELL LEVEL; CALCIUM CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CONVALESCENCE; DRUG CYTOTOXICITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG STRUCTURE; DRUG TARGETING; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOLECULAR IMAGING; NEUROPROTECTION; NONHUMAN; OXYGEN GLUCOSE DEPRIVATION REPERFUSION; PATCH CLAMP; PRIORITY JOURNAL; RAT; REPERFUSION;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; BRAIN ISCHEMIA; CALCIUM CHANNELS, L-TYPE; CELL CULTURE TECHNIQUES; CHO CELLS; CRICETINAE; CRICETULUS; CYTOPROTECTION; DISEASE MODELS, ANIMAL; GLUCOSE; MALE; MORPHINANS; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; OXYGEN; PATCH-CLAMP TECHNIQUES; PC12 CELLS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS;

EID: 80053254906     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01487.x     Document Type: Article

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