Inhibitory effects of berberine on ion channels of rat hepatocytes

World Journal of Gastroenterology

Volumn 10, Issue 19, 2004, Pages 2842-2845

  Wang, Fang ^a   Zhou, Hong Yi ^a   Zhao, Gang ^a   Fu, Li Ying ^a   Cheng, Lan ^a   Chen, Jian Guo ^a   Yao, Wei Xing ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BERBERINE; CALCIUM CHANNEL; CALCIUM ION; INWARDLY RECTIFYING POTASSIUM CHANNEL; ISOQUINOLINE ALKALOID; POTASSIUM CHANNEL; POTASSIUM ION; TETRYLAMMONIUM;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; CELL ISOLATION; CELL MEMBRANE POTENTIAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEART DISEASE; LIVER CELL; LIVER DISEASE; LIVER PROTECTION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; RAT;

EID: 4644233564     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v10.i19.2842     Document Type: Article

References (34)

1. Virtanen P, Lassila V, Njimi T, Mengata DE. Natural protoberberine alkaloids from Enantia chlorantha, palmatine, columbamine and jatrorrhizine for thioacetamide-traumatized rat liver. Acta anat 1988; 131: 166-170
2. Virtanen D, Lassila V, Njimi T, Ekotto Mengata D. Regeneration of D-galactosamine-traumatized rat liver with natural protoberberine alkaloids from Enantia chlorantha. Acta Anat 1988; 132: 159-163
3. Virtanen D, Lassila V, Njimi T, Mengata DE. Effect of splenectomy on hepasor treatment in allyl-alcohol-traumatized rat liver. Acta Anat 1989; 134: 301-304
4. Anis KV, Rajeshkumar NV, Kuttan R. Inhibition of chemical carcinogenesis by berberine in rats and mice. J Pharm Pharmacol 2001; 53: 763-768
5. Lau CW, Yao XQ, Chen ZY, Ko WH, Huang Y. Cardiovascular actions of berberine. Cardiovasc Drug Rev 2001; 19: 234-244
6. Bova S, Padrini R, Goldman WF, Berman DM, Cargnelli G. On the mechanism of vasodilating action of berberine: possible role of inositol lipid signaling system. J Pharmacol Exp Ther 1992; 261: 318-323
7. Amin AH, Subbaiah TV, Abbasi KM. Berberine sulfate: antimicrobial activity, bioassay, and mode of action. Can J Microbiol 1969; 15: 1067-1076
8. Tsai CS, Ochillo RF. Pharmacological effects of berberine on the longitudinal muscle of the guinea-pig isolated ileum. Arch Int Pharmacodyn Ther 1991; 310: 116-131
9. Wang YX, Zheng YM. Ionic mechanism responsible for prolongation of cardiac action-potential duration by berberine. J Cardiovasc Pharmacol 1997; 30: 214-222
10. Hwang JM, Wang CJ, Chou FP, Tseng TH, Hsieh YS, Lin WL, Chu CY. Inhibitory effect of berberine on tert-butyl hydroperoxide-induced oxidative damage in rat liver. Arch Toxicol 2002; 76: 664-670
11. K, and HERG channels of cardiac myocytes. Acta Pharmacol Sin 2001; 22: 125-131
12. Li Y, Fu LY, Yao WX, Xia GJ, Jiang MX. Effects of benzyltetrahy-dropalmatine on potassium currents in guinea pig and rat ventricular myocytes. Acta Pharmacol Sin 2002; 23: 612-616
13. Seglen PO. Preparation of isolated rat liver cells. Methods Cell Biol 1976; 13: 29-83
14. 2+ efflux in rat liver mitochondria. Role of membrane potential. Eur J Biochem 1983; 134: 377-383
15. Einarsson C, Ellis E, Abrahamsson A, Ericzon BG, Björkhem I, Axelson M. Bile acid formation in primary human hepatocytes. World J Gastroenterol 2000; 6: 522-525
16. Roman R, Feranchak AP, Troetsch M, Dunkelberg JC, Kilic G, Schlenker T, Schaack J, Fitz JG. Molecular characterization of volume-sensitive SK (Ca) channels in human liver cell lines. Am J Physiol Gastrointest Liver Physiol 2002; 282: G116-G122
17. vom Dahl S, Hallbrucker C, Lang F, Haussinger D. Regulation of cell volume in the perfused rat liver by hormones. Biochem J 1991; 280(Pt 1): 105-109
18. Devin A, Espie P, Guerin B, Rigoulet M. Energetics of swelling in isolated hepatocytes: a comprehensive study. Mol Cell Biochem 1998; 184: 107-121
19. + in voltage-gated potassium channels. Evidence for cation binding sites of different affinity. J Gen Physiol 1998; 111: 195-206
20. 2+ and TEA occur through different pathways in the rat liver. Am J Physiol 1999; 276(1 Pt 1): G43-G48
21. Hill CE, Briggs MM, Liu J, Magtanong L. Cloning, expression, and localization of a rat hepatocyte inwardly rectifying potassium channel. Am J Physiol Gastrointest Liver Physiol 2002; 282: G233-G240
22. Nietsch HH, Roe MW, Fiekers JF, Moore AL, Lidofsky SD. Activation of potassium and chloride channels by tumor necrosis factor α. Role in liver cell death. J Biol Chem 2000; 275: 20556-20561
23. Churchill TA, Fuller BJ. Effects of sodium and potassium channel antagonists on the energy metabolism of rat liver during cold storage. Transplantation 1995; 59: 904-907
24. Breit S, Kolb HA, Haussinger D, Lang F. Effects of tetrabutylhydroperoxide on hepatocyte ion channels. Cell Physiol Biochem 1999; 9: 133-138
25. 4 intoxication. Am J Pathol 1970; 58: 499-508
26. 4 and bile salt treatment of rats. Life Sci 1979; 25: 2043-2050
27. Burczynski FJ, Wang GQ, Minuk GY, Rosser B. Altered transmembrane ionic flux in hepatocytes isolated from cirrhotic rats. J Hepatol 1999; 30: 492-497
28. Janbaz KH, Gilani AH. Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents. Fitoterapia 2000; 71: 25-33
29. Isozaki H, Fujii K, Nomura E, Hara H. Calcium concentration in hepatocytes during liver ischaemia-reperfusion injury and the effects of diltiazem and citrate on perfused rat liver. Eur J Gastroenterol Hepatol 2000; 12: 291-297
30. Farghali H, Kmonickova E, LotKova H, Martinek J. Evaluation of calcium channel blockers as potential hepatoprotective agents in oxidative stress injury of perfused hepatocytes. Physiol Res 2000; 49: 261-268
31. + channel is present in guinea-pig but lacking in rat hepatocytes. Jpn J Physiol 1992; 42: 415-430
32. 2+ identified by patch-clamp recording in rat liver cells. Hepatology 2001; 33: 938-947
33. Xu SZ, Zhang Y, Ren JY, Zhou ZN. Effects of berberine on L- and T-type calcium channels in guinea pig ventricular myocytes. Zhongguo Yaoli Xuebao 1997; 18: 515-518
34. Brunton CC. In pharmacological basis of therapeutics edited by Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG. New York: McGraw Hill 1996: 917-936