Sinomenine influences capacity for invasion and migration in activated human monocytic THP-1 cells by inhibiting the expression of MMP-2, MMP-9, and CD147

Acta Pharmacologica Sinica

Volumn 30, Issue 4, 2009, Pages 435-441

  Ou, Yang Qiong ^a   Chen, Li Hua ^a   Li, Xue Jun ^a   Lin, Zhi Bin ^a   Li, Wei Dong ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

CD147; Invasion; Migration; MMP 2; MMP 9; Rheumatoid arthritis; Sinomenine

Indexed keywords

ALKALOID; CD147 ANTIGEN; GELATINASE A; GELATINASE B; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; SINOMENINE; BSG PROTEIN, HUMAN; IMMUNOSUPPRESSIVE AGENT; MORPHINAN DERIVATIVE;

ARTICLE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DRUG INHIBITION; FLOW CYTOMETRY; FLOW MEASUREMENT; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROPHAGE; MEDICINAL PLANT; REAL TIME POLYMERASE CHAIN REACTION; SINOMENIUM ACUTUM; ZYMOGRAPHY; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CELL SURVIVAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; MONOCYTE; PHYSIOLOGY; RHEUMATOID ARTHRITIS;

ANTIGENS, CD147; ARTHRITIS, RHEUMATOID; CELL DIFFERENTIATION; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MONOCYTES; MORPHINANS;

EID: 65249123058     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.21     Document Type: Article

References (26)

1. Zhou H, Wong YF, Wang J, Cai X, Liu L. Sinomenine ameliorates arthritis via MMPs, TIMPs, and cytokines in rats. Biochem Biophys Res Commun 2008; 376: 352-7.
2. Hua H, Chen X. Mechanistic study of sinomenine on analgesic and anti-inflammatory actions. J Xi-an Med Univ 1989; 4: 346-9. Chinese.
3. Liu L, Buchner E, Beitze D, Schmidt-Weber CB, Kaever V, Emmrich F, et al. Amelioration of rat experimental arthritides by treatment with the alkaloid sinomenine. Int J Immunopharmacol 1996; 18: 529-43.
4. Li L, Zhang CL, Song BW. Research of the pharmacological efect of sinomenine and clinical application. Tradit Chin Drug Res Clin Pharmacol 2006; 7: 17-4. Chinese.
5. Li XJ, Yue PY, Ha WY, Wong DY, Tin MM, Wang PX, et al. Efect of sinomenine on gene expression of the IL-1β-activated human synovial sarcoma. Life Sci 2006; 79: 665-73.
6. Yamasaki H. Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum. Acta Med Okayama 1976; 30: 1-20.
7. Wang Y, Fang YF, Huang WH, Zhou X, Wang MH, Zhong B, et al. Efect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats. J Ethnopharmacol 2005; 98: 37-43.
8. Li F, Li XF, Hu XF, Wang XX, Xu K, Chen Z. Te serum matrix metalloproteinase-9 level and its signifcance in rheumatoid arthritis. Chin J Rheumatol 2005; 9: 554-6. Chinese.
9. Gabison EE, Hoang-Xuan T, Menashi S. EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair. Biochimie 2005; 87: 361-8.
10. Liu JH, Li WD, Teng HL, Lin ZB. Immunopharmacological action of sinomenine, an alkaloid isolated from Sinomenium acutum, and its mechanism of action in treating rheumatoid arthritis. Acta Pharm Sin 2005; 40: 127-31.
11. Liu L, Buchner E, Beitze D, Schmidt-Weber CB, Kaever V, Emmrich F, et al. Amelioration of rat experimental arthritides by treatment with the alkaloid sinomenine. Int J Immunopharmacol 1996; 18: 529-43.
12. Kok TW, Yue PY, Mak NK, Fan TP, Liu L, Wong RN. Te anti-angiogenic efect of sinomenine. Angiogenesis 2005; 8: 3-12.
13. Bremner TA, Chaterjee D, Han ZY, Tsan MF, Wyche JH. THP-1 monocytic leukemia cells express Fas ligand constitutively and kill Fas-positive Jurkat cells. Leuk Res 1999; 23: 865-70.
14. Cao QZ, Lin ZB. Ganoderma lucidum polysaccharides peptide inhibits the growth of vascular endothelial cell and the induction of VEGF in human lung cancer cell. Life Sci 2006; 78: 1457-63.
15. Lee SK, Chun HK, Yang JY, Han DC, Son KH, Kwon BM. Inhibitory efect of obovatal on the migration and invasion of HT1080 cells via the inhibition of MMP-2. Bioorg Med Chem 2007; 15: 4085-90.
16. Haa KT, Kim KW, Suh SJ, Kwak CG, Kima JK, Kimb CH. Inhibitory effect of Uncaria sinensis on human aortic smooth muscle cell migration is based on matrix metalloproteinase-9 inhibitory. Environ Toxicol Pharmacol 2007; 24: 218-22.
17. Zhang B, Wu KF, Cao ZY, Rao Q, Ma XT, Zheng GG, et al. IL-18 increases invasiveness of HL-60 myeloid leukemia cells: up-regulation of matrix metalloproteinases-9 (MMP-9) expression. Expe Eye Res 2007; 84: 960-72.
18. Cheng H, Xia B, Guo QS, Zhang L, Wang F, Jiang L, et al. Sinomenine attenuates 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice. Int Immunopharmacol 2007; 7: 604-11.
19. Zylberberg C, Seamon V, Ponomareva O, Vellala K, Deighan M, Azzarolo AM. Estrogen up-regulation of metalloproteinase-2 and -9 expression in rabbit lacrimal glands. Exp Eye Res 2007; 84: 960-72.
20. Ellis SM, Nabeshima K, Biswas C. Monoclonal antibody preparation and purifcation of a tumor cell collagenase-stimulatory factor. Cancer Res 1989; 49: 3385-91.
21. Kataoka H, DeCastro R, Zucker S, Biswas C. Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase. Cancer Res 1993; 53: 3154-8.
22. Guo H, Zucker S, Gordon MK, Toole BP, Biswas C. Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells. J Biol Chem 1997; 272: 24-7.
23. Taylor PM, Woodfield RJ, Hodgkin MN, Pettitt TR, Martin A, Kerr DJ, et al. Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A(2) and 5-lipoxygenase catalyzed pathway. Oncogene 2002; 21: 5765-72.
24. Polete M, Gilles C, Marchand V, Lorenzato M, Toole B, Tournier JM. Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers. J Histochem Cytochem 1997; 45: 703-9.
25. Tsuchiya S, Yamabe M, Yamaguchi Y, Kobayashi Y, Konno T, Tada K. Establishment and characterization of a human acute monocytic leukemia cell line. Int J Cancer 1980; 26: 171-6.
26. Traore K, Trush MA, George M Jr, Spannhake EW, Anderson W, Assefa A. Signal transduction of phorbol 12-myristate 13-acetate (PMA)-induced growth inhibition of human monocytic leukemia THP-1 cells is reactive oxygen dependent. Leuk Res 2005; 29: 863-79.