Nimodipine improves the disruption of spatial cognition induced by cerebral ischemia

Physiology and Behavior

Volumn 70, Issue 1-2, 2000, Pages 19-25

  Taya, Koji ^a   Watanabe, Yasuo ^b   Kobayashi, Hirotoshi ^c   Fujiwara, Michihiro ^c  

^a BAYER YAKUHIN LTD   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

^c FUKUOKA UNIVERSITY   (Japan)

Author keywords

Neuroprotection; Nimodipine; Primary brain cell culture; Repeated cerebral ischemia; Spatial cognition

Indexed keywords

AMLODIPINE; CALCIUM ANTAGONIST; CALCIUM ION; NIMODIPINE;

ACIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DAMAGE; CEREBELLUM; CONTROLLED STUDY; GRANULE CELL; HYPOGLYCEMIA; MALE; MAZE TEST; MEMORY; MITOCHONDRION; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL DISCRIMINATION; SPATIAL MEMORY; TASK PERFORMANCE;

EID: 0034661026     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(00)00221-3     Document Type: Article

References (37)

1. Belayev L., Busto R., Ikeda M., Rubin L.L., Kajiwara A., Morgan L., Ginsberg M.D. Protection against blood-brain barrier disruption in focal cerebral ischemia by the type IV phosphodiesterase inhibitor BBB022. a quantitative study Brain Res. 787:1998;277-285.
2. Benyó Z., De Jong G.I., Luiten P.G.M. Nimodipine prevents early loss of hippocampal CA1 parvalbumin imunoreactivity after focal cerebral ischemia in the rat. Brain Res Bull. 36:1995;569-572.
3. Calle P.A., Paridaens K., De Ridder L.I., Buylaert W.A. Failure of nimodipine to prevent brain damage in a global brain ischemia model in the rat. Resuscitation. 25:1993;59-71.
4. Chung E., Iwasaki K., Fujiwara M. Repeated cerebral ischemia induced hippocampal cell death and disruption of spatial cognition in the rat. Brain Res. in press:2000.
5. Grotta J. Why do all drugs work in animals but none in stroke patients? 2. Neuroprotective therapy. J Intern Med (Engl). 237:1995;89-94.
6. 2+ channel responses and their coupling to exocytosis in cultured cerebellar granule cells. Neuroscience. 77:1997;683-694.
7. Hayashi H., Watanabe Y., Shibuya T. Relation between long-lasting amounts of excitatory amino acid and its neuronal uptake system in cultured cerebellar granule cells under hypoglycemia. Prog Neuropsychopharmacol Biol Psychiatry. 17:1993;463-474.
8. Heininger K. Neuroprotective potential of nimodipine, a cerebral calcium antagonist. Inoue K., Watanabe Y. Calcium Ion Modulators; the New Wave of Psychotropic Drugs. 1998;41-56 Harwood Academic Publishers, Amsterdam, the Netherlands.
9. 2-melanocyte-stimulating hormone and nimodipine on cortical blood flow and infarction volume in two rat models of middle cerebral artery occlusion. Eur J Pharmacol. 306:1996;113-121.
10. Ishibashi H., Arima J., Rhee J.S., Akaike N. Modulation of high-voltage-activated calcium channels in rat CNS neurons. Inoue K., Watanabe Y. Calcium Ion Modulators; the New Wave of Psychotropic Drugs. 1998;1-12 Harwood Academic Publishers, Amsterdam, the Netherlands.
11. Iwasaki K., Kitamura Y., Ohgami Y., Mishima K., Fujiwara M. The disruption of spatial cognition and changes in brain amino acid, monoamine and acetylcholine in rats with transient cerebral ischemia. Brain Res. 709:1996;163-172.
12. Manev H., Kharlamov E., Uz T., Mason R.P., Cagnoli C.M. Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells. Exp Neurol. 146:1997;171-178.
13. Matyja E. Intracellular calcium overload in a model of quinolinic acid neurotoxicity in organotypic culture of rat hippocampus; inhibited by nimodipine. Folia Neuropathol. 35:1997;8-17.
14. Ohnishi M., Watanabe Y., Shibuya T. Potentiation of excito-toxicity by glutamate uptake inhibitor rather than glutamine synthetase inhibitor. Jpn J Pharmacol. 68:1995;315-321.
15. 3H]nimodipine in focal cerebral ischemia. modulation by hyperglycemia J Cereb Blood Flow Metab. 17:1997;1057-1065.
16. Patel V.B., Siddiq T., Sherwood R., Richardson P.J., Preedy V.R. Effect of the dihydropyridine calcium channel blocker amlodipine on ventricular and atrial protein synthesis in an aortic constriction model of hypertension and, following chronic treatment, in the left ventricle SHR rats. Int J Cardiol. 58:1997;241-255.
17. Pluta R., Misicka A., Januszewski S., Barcikowska M., Lipkowski A.W. Transport of human β-amyloid peptide through the rat blood-brain barrier after global cerebral ischemia. Acta Neurochir (Wien). 70(suppl.):1997;247-249.
18. Pulsinelli W.A., Brierley J.B. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke. 10:1979;267-272.
19. Rami A., Krieglstein J. Neuronal protective effects of calcium antagonists in cerebral ischemia. Life Sci. 55:1994;2105-2113.
20. Roda J.M., Carceller F., Díez-Tejedor E., Avendaño C. Reduction of infarct size by intra-arterial nimodipine administerd at reperfusion in a rat model of partially reversible brain focal ischemia. Stroke. 26:1995;1888-1892.
21. Santos M.S., Moreno A.J., Carvalho A.P. Relationships between ATP depletion, membrane potential, and the release of neurotransmitters in rat nerve terminals. An in vitro study under conditions that mimic anoxia, hypoglycemia, and ischemia. Stroke. 27:1996;941-950.
22. Shukitt-Hale B., Stillman M.J., Levy A., Devine J.A., Lieberman H. Nimodipine prevents the in vivo decrease in hippocampal extracellular acetylcholine produced by hypobaric hypoxia. Brain Res. 621:1993;291-295.
23. Smith M.L., Kogåtröm E., Rosén I., Siesjö B.K. Effect of the calcium antagonists nimodipine on the delayed hyperfusion following incomplete ischemia in the rat. J Cereb Blood Flow Metabol. 3:1983;543-546.
24. Strosznajder J., Chalimoniuk M., Strosznajder R.P., Walski M., Lupo G., Anfuso C.D., Albanese V., Alberghina M. Arachidonate transport through the blood-retina and blood-brain barrier of the rat after reperfusion of varying duration following complete cerebral ischemia. Int J Dev Neurosci. 16:1998;103-113.
25. ++ antagonists. Hum Psychopharmacol Clin Exp. 13:1998;389-405.
26. Taya K., Zhang J., Hara I., Watanabe Y. Appearance of high sensitive cells to L-type Ca antagonists in cultured cerebellar granule cells. Jpn J Psychopharmacol. 19:1999;33-38.
27. + and N-type channel blockades Inoue K., Watanabe Y. Calcium Ion Modulators; the New Wave of Psychotropic Drugs. 1998;13-23 Harwood Academic Publishers, Amsterdam, the Netherlands.
28. Van Reempts J., Haseldonckx M., Van Deuren B., Wouters L., Borgers M. Structural damage of the ischemic brain. involvement of calcium and effects of postischemic treatment with calcium entry blockers Drug Dev Res. 8:1986;387-395.
29. Watanabe Y., Endo T., Zhang X.-Q.T., Matsuda M., Hasegawa K., Shibuya T. A newly developed method for quantal measurement of glia cells in cultured neuronal cells using a flow cytometer. Neuroscience. 17:1991;261-269.
30. Watanabe Y., Hara I., Li J., Matsumia T. Interaction between neurons and astrocytes involved in brain regulatory function as assessed by in vitro brain ischemia models. Folia Pharmacol Jpn. 109:1997;119-128.
31. Womack S., Geduldig P.S., Foley E.A., Forman J.B., Simsic M., Davis A.V., Feliciano J., Srisumrid T., Finger S. Medial frontal cortex lesions. deficits and treatment with nimodipine Exp Neurol. 124:1993;387-389.
32. ++ antagonists in relation to their pharmacokinetics in senescent brain. Inoue K., Watanabe Y. Calcium Ion Modulators; the New Wave of Psychotropic Drugs. 1998;25-39 Harwood Academic Publishers, Amsterdam, the Netherlands.
33. Yamada S., Uchida S., Ohkura T., Sugimoto N., Deguchi Y., Kimura R. Pharmacokinetics of a third-generation dihydropyridine calcium antagonist, amlodipine and its occupation of cardiovascular receptors. Jpn Pharmacol Ther. 23:1995;75-86.
34. Yamanaka K., Suzuki M., Munehasu S., Ishiko J. Antihypertensive effects of amlodipine, a new calcium antagonist. Folia Pharmacol Jpn. 97:1991;115-126.
35. Ying W., Han S.K., Miller J.W., Swanson R.A. Acidosis potentiated oxidative neuronal death by multiple mechanisms. J Neurochem. 73:1999;1549-1556.
36. Young W.L., Josovitz K., Morales O., Chien S. The effect of nimodipine on post-ischemic cerebral glucose utilization and blood flow in the rat. Anesthesiology. 67:1987;54-59.
37. 2+ levels increased by high-potassium or glutamate in cultured rat cerebellar granule cell. Jpn J Pharmacol. 62:1993;411-414.