Dextromethorphan is protective against sensitized N-methyl-D-aspartate receptor-mediated excitotoxic brain damage in the developing mouse brain

European Journal of Neuroscience

Volumn 27, Issue 4, 2008, Pages 874-883

  Keller, Matthias ^a   Griesmaier, Elke ^a   Auer, Maria ^a   Schlager, Gerald ^a   Urbanek, Martina ^a   Simbruner, Georg ^a   Gressens, Pierre ^c   Sárközy, Gergely ^b  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

Brain injury; Dextromethorphan; Excitotoxicity; Neonate; Newborn; Sensitization

Indexed keywords

CASPASE 3; DEXTROMETHORPHAN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHOSPHATE BUFFERED SALINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DAMAGE; BRAIN DEVELOPMENT; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; ENZYME DEGRADATION; EXCITOTOXICITY; GRAY MATTER; MICROGLIA; MOUSE; NERVE DEGENERATION; NEUROPATHOLOGY; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; WHITE MATTER;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BRAIN; CASPASE 3; DEXTROMETHORPHAN; DISEASE MODELS, ANIMAL; ENCEPHALOMALACIA; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; IBOTENIC ACID; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFLAMMATION; MALE; MICE; MICROGLIA; NEUROPROTECTIVE AGENTS; POLYMERASE CHAIN REACTION; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 40549105461     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2008.06062.x     Document Type: Article

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