A-type lamins and Hutchinson-Gilford progeria syndrome: Pathogenesis and therapy

Frontiers in Bioscience - Scholar

Volumn 3 S, Issue 3, 2011, Pages 1133-1146

  Gonzalez, Jose M ^a,c   Pla, Davinia ^a   Perez Sala, Dolores ^b   Andres, Vicente ^c  

^a INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^c Laboratory of Molecular and Genetic Cardiovascular Pathophysiology   (Spain)

Author keywords

A type lamins; Farnesyl Transferase Inhibitors; Hutchinson Gilford progeria syndrome; Laminopathies; Nuclear envelope; Restrictive Dermopathy; Review

Indexed keywords

4 [2 (4 CYANOPHENYL) 2 HYDROXY 2 (3 METHYLIMIDAZOL 4 YL)ETHOXY] 3 [4 (TRIFLUOROMETHOXY)PHENYL]BENZONITRILE; ANTISENSE OLIGONUCLEOTIDE; LAMIN A; LAMIN B; LAMIN C; LONAFARNIB; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; PEPTIDOMIMETIC AGENT; PRAVASTATIN; SALICYLATE SODIUM; SHORT HAIRPIN RNA; TIPIFARNIB; ZOLEDRONIC ACID; FARNESYL TRANS TRANSFERASE; NUCLEAR PROTEIN; PRELAMIN A; PROTEIN PRECURSOR;

ALTERNATIVE MEDICINE; ANTISENSE THERAPY; ARTICLE; CELL AGING; CELL NUCLEUS MEMBRANE; CLINICAL TRIAL (TOPIC); COMPETITIVE INHIBITION; DNA DAMAGE; ENZYME INHIBITION; GENE EXPRESSION; GENE MUTATION; HETEROCHROMATIN; HUMAN; LAMINOPATHY; NONHUMAN; NUCLEAR LAMINA; PHENOTYPE; PROGERIA; PROTEIN EXPRESSION; PROTEIN PRENYLATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; WILD TYPE; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CONGENITAL SKIN DISEASE; CONTRACTURE; DRUG ANTAGONISM; GENE THERAPY; GENETICS; METABOLISM; METHODOLOGY; MOUSE; REVIEW;

ANIMALIA; MAMMALIA; MURINAE;

ANIMALS; CONTRACTURE; FARNESYLTRANSTRANSFERASE; GENE THERAPY; HUMANS; LAMIN TYPE A; MICE; MODELS, BIOLOGICAL; NUCLEAR LAMINA; NUCLEAR PROTEINS; PROGERIA; PROTEIN PRECURSORS; SKIN ABNORMALITIES;

EID: 80053165077     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: None     Document Type: Article

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