Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production

Immunity

Volumn 35, Issue 3, 2011, Pages 426-440

  Li, Shitao ^a   Wang, Lingyan ^a   Berman, Michael ^a   Kong, Young Yun ^b   Dorf, Martin E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; LIPOPOLYSACCHARIDE; RNA;

ANIMAL CELL; ARTICLE; HUMAN; HUMAN CELL; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; VIRUS REPLICATION;

ANIMALS; CELL LINE; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON TYPE I; MICE; PROTEIN INTERACTION MAPPING; PROTEIN-SERINE-THREONINE KINASES; PROTEOMICS; UBIQUITINATION; VIRUS DISEASES; VIRUSES;

EID: 80053131464     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2011.06.014     Document Type: Article

References (55)

1. Abdullah J.M., Li X., Nachtman R.G., Jurecic R. FLRF, a novel evolutionarily conserved RING finger gene, is differentially expressed in mouse fetal and adult hematopoietic stem cells and progenitors. Blood Cells Mol. Dis. 2001, 27:320-333.
2. Ablasser A., Bauernfeind F., Hartmann G., Latz E., Fitzgerald K.A., Hornung V. RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate. Nat. Immunol. 2009, 10:1065-1072.
3. Akhouayri O., Quélo I., St-Arnaud R. Sequence-specific DNA binding by the alphaNAC coactivator is required for potentiation of c-Jun-dependent transcription of the osteocalcin gene. Mol. Cell. Biol. 2005, 25:3452-3460.
4. Bhoj V.G., Chen Z.J. Ubiquitylation in innate and adaptive immunity. Nature 2009, 458:430-437.
5. Carty M., Goodbody R., Schröder M., Stack J., Moynagh P.N., Bowie A.G. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat. Immunol. 2006, 7:1074-1081.
6. Chau T.L., Gioia R., Gatot J.S., Patrascu F., Carpentier I., Chapelle J.P., O'Neill L., Beyaert R., Piette J., Chariot A. Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?. Trends Biochem. Sci. 2008, 33:171-180.
7. Chiu Y.H., Macmillan J.B., Chen Z.J. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 2009, 138:576-591.
8. Colié S., Codogno P., Levade T., Andrieu-Abadie N. Regulation of cell death by sphingosine 1-phosphate lyase. Autophagy 2010, 6:426-427.
9. Ferran M.C., Lucas-Lenard J.M. The vesicular stomatitis virus matrix protein inhibits transcription from the human beta interferon promoter. J. Virol. 1997, 71:371-377.
10. Fitzgerald K.A., McWhirter S.M., Faia K.L., Rowe D.C., Latz E., Golenbock D.T., Coyle A.J., Liao S.M., Maniatis T. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat. Immunol. 2003, 4:491-496.
11. Friedman C.S., O'Donnell M.A., Legarda-Addison D., Ng A., Cárdenas W.B., Yount J.S., Moran T.M., Basler C.F., Komuro A., Horvath C.M., et al. The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. EMBO Rep. 2008, 9:930-936.
12. Gack M.U., Shin Y.C., Joo C.H., Urano T., Liang C., Sun L., Takeuchi O., Akira S., Chen Z., Inoue S., Jung J.U. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 2007, 446:916-920.
13. Gitlin L., Barchet W., Gilfillan S., Cella M., Beutler B., Flavell R.A., Diamond M.S., Colonna M. Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc. Natl. Acad. Sci. USA 2006, 103:8459-8464.
14. Huang S.M., Hancock M.K., Pitman J.L., Orth A.P., Gekakis N. Negative regulators of insulin signaling revealed in a genome-wide functional screen. PLoS ONE 2009, 4:e6871.
15. Ishii K.J., Kawagoe T., Koyama S., Matsui K., Kumar H., Kawai T., Uematsu S., Takeuchi O., Takeshita F., Coban C., Akira S. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature 2008, 451:725-729.
16. Ishikawa H., Barber G.N. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 2008, 455:674-678.
17. Itoh M., Kim C.H., Palardy G., Oda T., Jiang Y.J., Maust D., Yeo S.Y., Lorick K., Wright G.J., Ariza-McNaughton L., et al. Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev. Cell 2003, 4:67-82.
18. Jin Y., Blue E.K., Dixon S., Shao Z., Gallagher P.J. A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK. J. Biol. Chem. 2002, 277:46980-46986.
19. Kato H., Sato S., Yoneyama M., Yamamoto M., Uematsu S., Matsui K., Tsujimura T., Takeda K., Fujita T., Takeuchi O., Akira S. Cell type-specific involvement of RIG-I in antiviral response. Immunity 2005, 23:19-28.
20. Kato H., Takeuchi O., Sato S., Yoneyama M., Yamamoto M., Matsui K., Uematsu S., Jung A., Kawai T., Ishii K.J., et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006, 441:101-105.
21. Kawai T., Takahashi K., Sato S., Coban C., Kumar H., Kato H., Ishii K.J., Takeuchi O., Akira S. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 2005, 6:981-988.
22. Kim T., Pazhoor S., Bao M., Zhang Z., Hanabuchi S., Facchinetti V., Bover L., Plumas J., Chaperot L., Qin J., Liu Y.J. Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells. Proc. Natl. Acad. Sci. USA 2010, 107:15181-15186.
23. Koo B.K., Lim H.S., Song R., Yoon M.J., Yoon K.J., Moon J.S., Kim Y.W., Kwon M.C., Yoo K.W., Kong M.P., et al. Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Development 2005, 132:3459-3470.
24. Koo B.K., Yoon K.J., Yoo K.W., Lim H.S., Song R., So J.H., Kim C.H., Kong Y.Y. Mind bomb-2 is an E3 ligase for Notch ligand. J. Biol. Chem. 2005, 280:22335-22342.
25. Koo B.K., Yoon M.J., Yoon K.J., Im S.K., Kim Y.Y., Kim C.H., Suh P.G., Jan Y.N., Kong Y.Y. An obligatory role of mind bomb-1 in notch signaling of mammalian development. PLoS ONE 2007, 2:e1221.
26. Li S., Wang L., Berman M.A., Zhang Y., Dorf M.E. RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling. Mol. Cell 2006, 24:497-509.
27. Meylan E., Curran J., Hofmann K., Moradpour D., Binder M., Bartenschlager R., Tschopp J. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 2005, 437:1167-1172.
28. Nogami S., Satoh S., Tanaka-Nakadate S., Yoshida K., Nakano M., Terano A., Shirataki H. Identification and characterization of taxilin isoforms. Biochem. Biophys. Res. Commun. 2004, 319:936-943.
29. Oka T., Sayano T., Tamai S., Yokota S., Kato H., Fujii G., Mihara K. Identification of a novel protein MICS1 that is involved in maintenance of mitochondrial morphology and apoptotic release of cytochrome c. Mol. Biol. Cell 2008, 19:2597-2608.
30. Otsuka M., Jing Q., Georgel P., New L., Chen J., Mols J., Kang Y.J., Jiang Z., Du X., Cook R., et al. Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression. Immunity 2007, 27:123-134.
31. Panne D., Maniatis T., Harrison S.C. An atomic model of the interferon-beta enhanceosome. Cell 2007, 129:1111-1123.
32. Paz S., Vilasco M., Arguello M., Sun Q., Lacoste J., Nguyen T.L., Zhao T., Shestakova E.A., Zaari S., Bibeau-Poirier A., et al. Ubiquitin-regulated recruitment of IkappaB kinase epsilon to the MAVS interferon signaling adapter. Mol. Cell. Biol. 2009, 29:3401-3412.
33. Perry A.K., Chow E.K., Goodnough J.B., Yeh W.C., Cheng G. Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection. J. Exp. Med. 2004, 199:1651-1658.
34. Ryzhakov G., Randow F. SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK. EMBO J. 2007, 26:3180-3190.
35. Saitoh T., Fujita N., Hayashi T., Takahara K., Satoh T., Lee H., Matsunaga K., Kageyama S., Omori H., Noda T., et al. Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Proc. Natl. Acad. Sci. USA 2009, 106:20842-20846.
36. Satoh T., Kato H., Kumagai Y., Yoneyama M., Sato S., Matsushita K., Tsujimura T., Fujita T., Akira S., Takeuchi O. LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses. Proc. Natl. Acad. Sci. USA 2010, 107:1512-1517.
37. Seth R.B., Sun L., Ea C.K., Chen Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005, 122:669-682.
38. Sharma S., tenOever B.R., Grandvaux N., Zhou G.P., Lin R., Hiscott J. Triggering the interferon antiviral response through an IKK-related pathway. Science 2003, 300:1148-1151.
39. Song R., Kim Y.W., Koo B.K., Jeong H.W., Yoon M.J., Yoon K.J., Jun D.J., Im S.K., Shin J., Kong M.P., et al. Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell development. J. Exp. Med. 2008, 205:2525-2536.
40. Stetson D.B., Medzhitov R. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 2006, 24:93-103.
41. Takaoka A., Wang Z., Choi M.K., Yanai H., Negishi H., Ban T., Lu Y., Miyagishi M., Kodama T., Honda K., et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 2007, 448:501-505.
42. Takeuchi O., Akira S. Pattern recognition receptors and inflammation. Cell 2010, 140:805-820.
43. Tattoli I., Carneiro L.A., Jéhanno M., Magalhaes J.G., Shu Y., Philpott D.J., Arnoult D., Girardin S.E. NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production. EMBO Rep. 2008, 9:293-300.
44. Tsuchida T., Zou J., Saitoh T., Kumar H., Abe T., Matsuura Y., Kawai T., Akira S. The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA. Immunity 2010, 33:765-776.
45. Tsukahara T., Kimura S., Ichimiya S., Torigoe T., Kawaguchi S., Wada T., Yamashita T., Sato N. Scythe/BAT3 regulates apoptotic cell death induced by papillomavirus binding factor in human osteosarcoma. Cancer Sci. 2009, 100:47-53.
46. Unterholzner L., Keating S.E., Baran M., Horan K.A., Jensen S.B., Sharma S., Sirois C.M., Jin T., Latz E., Xiao T.S., et al. IFI16 is an innate immune sensor for intracellular DNA. Nat. Immunol. 2010, 11:997-1004.
47. Wang C., Chen T., Zhang J., Yang M., Li N., Xu X., Cao X. The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon. Nat. Immunol. 2009, 10:744-752.
48. Wilkins C., Gale M. Recognition of viruses by cytoplasmic sensors. Curr. Opin. Immunol. 2010, 22:41-47.
49. Wu J.I., Rajendra R., Barsi J.C., Durfee L., Benito E., Gao G., Kuruvilla M., Hrdlicková R., Liss A.S., Artzt K. Targeted disruption of Mib2 causes exencephaly with a variable penetrance. Genesis 2007, 45:722-727.
50. Xu L.G., Wang Y.Y., Han K.J., Li L.Y., Zhai Z., Shu H.B. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol. Cell 2005, 19:727-740.
51. Yanagisawa H., Miyashita T., Nakano Y., Yamamoto D. HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death. Cell Death Differ. 2003, 10:798-807.
52. Yoneyama M., Kikuchi M., Natsukawa T., Shinobu N., Imaizumi T., Miyagishi M., Taira K., Akira S., Fujita T. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 2004, 5:730-737.
53. Yoshida K., Nogami S., Satoh S., Tanaka-Nakadate S., Hiraishi H., Terano A., Shirataki H. Interaction of the taxilin family with the nascent polypeptide-associated complex that is involved in the transcriptional and translational processes. Genes Cells 2005, 10:465-476.
54. Zeng W., Xu M., Liu S., Sun L., Chen Z.J. Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3. Mol. Cell 2009, 36:315-325.
55. Zhao T., Yang L., Sun Q., Arguello M., Ballard D.W., Hiscott J., Lin R. The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways. Nat. Immunol. 2007, 8:592-600.