Modulation of mutant huntingtin N-terminal cleavage and its effect on aggregation and cell death

Neurotoxicity Research

Volumn 20, Issue 2, 2011, Pages 120-133

  Juenemann, Katrin ^a   Weisse, Christina ^a   Reichmann, Denise ^a   Kaether, Christoph ^a   Calkhoven, Cornelis F ^a   Schilling, Gabriele ^a  

^a FRITZ LIPMANN INSTITUTE   (Germany)

Author keywords

Huntingtin; Huntington's disease; N terminal fragment; Polyglutamine; Proteolytic processing

Indexed keywords

CASPASE 3; CASPASE 7; HUNTINGTIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL AGGREGATION; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOUSE; NONHUMAN; PEPTIDE MAPPING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; SITE DIRECTED MUTAGENESIS;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 7; CELL AGGREGATION; CELL COUNT; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; EPITOPE MAPPING; HUMANS; MICE; MUTANT PROTEINS; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; TRANSFECTION; TRINUCLEOTIDE REPEAT EXPANSION;

ANIMALIA;

EID: 80052644148     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-010-9227-6     Document Type: Article

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