Kaempferol acts through mitogen-activated protein kinases and protein kinase B/AKT to elicit protection in a model of neuroinflammation in BV2 microglial cells

British Journal of Pharmacology

Volumn 164, Issue 3, 2011, Pages 1008-1025

  Park, S E ^a   Sapkota, K ^a,b   Kim, S ^c   Kim, H ^d   Kim, S J ^a  

^a Chosun University   (South Korea)

^b TRIBHUVAN UNIVERSITY   (Nepal)

^c Kwangju University   (South Korea)

^d Chonnam National University Medical School   (South Korea)

Author keywords

AKT; kaempferol; lipopolysaccharide; microglia; mitogen activated protein kinases; neuroinflammation; NF B

Indexed keywords

CYCLOOXYGENASE 2; DICHLORODIHYDROFLUORESCEIN DIACETATE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; KAEMPFEROL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROSTAGLANDIN E2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; STROMELYSIN; TETRAZOLIUM; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; DRUG INHIBITION; DRUG STRUCTURE; ENCEPHALITIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; MICROGLIA; MOUSE; NEUROPROTECTION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL SURVIVAL; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; INTERLEUKIN-1BETA; KAEMPFEROLS; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASE 3; MICE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHAGOCYTOSIS; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80052560168     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01389.x     Document Type: Article

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