-
1
-
-
31144453053
-
A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes
-
Ackerley S, James P A, Kalli A et al (2006) A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes. Hum Mol Genet 15:347-354
-
(2006)
Hum Mol Genet
, vol.15
, pp. 347-354
-
-
Ackerley, S.1
James, P.A.2
Kalli, A.3
-
2
-
-
37349032463
-
Effect of phosphorylation on alpha B-crystallin: Differences in stability, subunit exchange and chaperone activity of homo and mixed oligomers of alpha B-crystallin and its phosphorylation-mimicking mutant
-
Ahmad M F, Raman B, Ramakrishna T et al (2008) Effect of phosphorylation on alpha B-crystallin: differences in stability, subunit exchange and chaperone activity of homo and mixed oligomers of alpha B-crystallin and its phosphorylation-mimicking mutant. J Mol Biol 375:1040-1051
-
(2008)
J Mol Biol
, vol.375
, pp. 1040-1051
-
-
Ahmad, M.F.1
Raman, B.2
Ramakrishna, T.3
-
3
-
-
0037827756
-
The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death
-
Akbar M T, Lundberg A M, Liu K et al (2003) The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death. J Biol Chem 278:19956-19965
-
(2003)
J Biol Chem
, vol.278
, pp. 19956-19965
-
-
Akbar, M.T.1
Lundberg, A.M.2
Liu, K.3
-
4
-
-
35548948039
-
Heat shock factors at a crossroad between stress and development
-
Akerfelt M, Trouillet D, Mezger V et al (2007) Heat shock factors at a crossroad between stress and development. Ann N Y Acad Sci 1113:15-27
-
(2007)
Ann N Y Acad Sci
, vol.1113
, pp. 15-27
-
-
Akerfelt, M.1
Trouillet, D.2
Mezger, V.3
-
5
-
-
0037155819
-
The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis
-
Andley U P, Patel H C, Xi J H (2002) The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis. J Biol Chem 277:10178-86
-
(2002)
J Biol Chem
, vol.277
, pp. 10178-10186
-
-
Andley, U.P.1
Patel, H.C.2
Xi, J.H.3
-
6
-
-
0035806346
-
Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse
-
Armstrong C L, Krueger-Naug A M, Currie R W et al (2001) Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse. J Comp Neurol 434:262-274
-
(2001)
J Comp Neurol
, vol.434
, pp. 262-274
-
-
Armstrong, C.L.1
Krueger-Naug, A.M.2
Currie, R.W.3
-
7
-
-
18444366777
-
In search of the molecular mechanism by which small stress proteins counteract apoptosis during cellular differentiation
-
Arrigo A P (2005) In search of the molecular mechanism by which small stress proteins counteract apoptosis during cellular differentiation. J Cell Biochem 94:241-246
-
(2005)
J Cell Biochem
, vol.94
, pp. 241-246
-
-
Arrigo, A.P.1
-
8
-
-
34447631538
-
Hsp27 (HspB1) and alphaB-crystallin (HspB5) as therapeutic targets
-
Arrigo A P, Simon S, Gibert B et al (2007) Hsp27 (HspB1) and alphaB-crystallin (HspB5) as therapeutic targets. FEBS Lett 581:3665-3674
-
(2007)
FEBS Lett
, vol.581
, pp. 3665-3674
-
-
Arrigo, A.P.1
Simon, S.2
Gibert, B.3
-
9
-
-
34248176724
-
Heat shock genes - Integrating cell survival and death
-
Arya R, Mallik M, and Lakhotia S C (2007) Heat shock genes - integrating cell survival and death. J Biosci 32:595-610
-
(2007)
J Biosci
, vol.32
, pp. 595-610
-
-
Arya, R.1
Mallik, M.2
Lakhotia, S.C.3
-
10
-
-
0018382014
-
The induction of gene activity in drosophilia by heat shock
-
Ashburner M and Bonner J J (1979) The induction of gene activity in drosophilia by heat shock. Cell 17:241-254
-
(1979)
Cell
, vol.17
, pp. 241-254
-
-
Ashburner, M.1
Bonner, J.J.2
-
11
-
-
34548557727
-
Up-regulation of tau, a brain microtubule-associated protein, in lens cortical fractions of aged alphaA-, alphaB-, and alphaA/B-crystallin knockout mice
-
Bai F, Xi J H, Andley U P (2007) Up-regulation of tau, a brain microtubule-associated protein, in lens cortical fractions of aged alphaA-, alphaB-, and alphaA/B-crystallin knockout mice. Mol Vis 13:1589-600
-
(2007)
Mol Vis
, vol.13
, pp. 1589-1600
-
-
Bai, F.1
Xi, J.H.2
Andley, U.P.3
-
12
-
-
0037707633
-
High threshold for induction of the stress response in motor neurons is associated with failure to activate HSF1
-
Batulan Z, Shinder G A, Minotti S et al (2003) High threshold for induction of the stress response in motor neurons is associated with failure to activate HSF1. J Neurosci 23:5789-5798
-
(2003)
J Neurosci
, vol.23
, pp. 5789-5798
-
-
Batulan, Z.1
Shinder, G.A.2
Minotti, S.3
-
13
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence N F, Sampat R M, Kopito R R (2001) Impairment of the ubiquitin-proteasome system by protein aggregation. Science 292:1552-5
-
(2001)
Science
, vol.292
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
14
-
-
0028071812
-
Phosphorylation and supramolecular organization of murine small heat shock protein HSP25 abolish its actin polymerization-inhibiting activity
-
Benndorf R, Hayess K, Ryazantsev S et al (1994) Phosphorylation and supramolecular organization of murine small heat shock protein HSP25 abolish its actin polymerization-inhibiting activity. J Biol Chem 269:20780-20784
-
(1994)
J Biol Chem
, vol.269
, pp. 20780-20784
-
-
Benndorf, R.1
Hayess, K.2
Ryazantsev, S.3
-
15
-
-
0035920143
-
HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D) HSP27)
-
Benndorf R, Sun X, Gilmont R R et al (2001) HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D) HSP27). J Biol Chem 276:26753-61
-
(2001)
J Biol Chem
, vol.276
, pp. 26753-26761
-
-
Benndorf, R.1
Sun, X.2
Gilmont, R.R.3
-
16
-
-
0037108280
-
A positive charge preservation at position 116 of alpha A-crystallin is critical for its structural and functional integrity
-
Bera S, Thampi P, Cho W J et al (2002) A positive charge preservation at position 116 of alpha A-crystallin is critical for its structural and functional integrity. Biochemistry 41:12421-12426
-
(2002)
Biochemistry
, vol.41
, pp. 12421-12426
-
-
Bera, S.1
Thampi, P.2
Cho, W.J.3
-
17
-
-
0037039153
-
The alphaA-crystallin R116C mutant has a higher affinity for forming heteroaggregates with alphaB-crystallin
-
Bera S, Abraham E C (2002) The alphaA-crystallin R116C mutant has a higher affinity for forming heteroaggregates with alphaB-crystallin. Biochemistry 41:297-305
-
(2002)
Biochemistry
, vol.41
, pp. 297-305
-
-
Bera, S.1
Abraham, E.C.2
-
18
-
-
0034765821
-
Alpha-B crystallin gene (CRYAB) mutation causes dominant congenital posterior polar cataract in humans
-
Berry V, Francis P, Reddy M A et al (2001) Alpha-B crystallin gene (CRYAB) mutation causes dominant congenital posterior polar cataract in humans. Am J Hum Genet 69:1141-1145
-
(2001)
Am J Hum Genet
, vol.69
, pp. 1141-1145
-
-
Berry, V.1
Francis, P.2
Reddy, M.A.3
-
19
-
-
5644275139
-
Role of ATP on the interaction of alpha-crystallin with its substrates and its implications for the molecular chaperone function
-
Biswas A and Das K P (2004) Role of ATP on the interaction of alpha-crystallin with its substrates and its implications for the molecular chaperone function. J Biol Chem 279:42648-42657
-
(2004)
J Biol Chem
, vol.279
, pp. 42648-42657
-
-
Biswas, A.1
Das, K.P.2
-
20
-
-
1642569697
-
DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity
-
Boellmann F, Guettouche T, Guo Y et al (2004) DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity. Proc Natl Acad Sci U S A 101:4100-4105
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 4100-4105
-
-
Boellmann, F.1
Guettouche, T.2
Guo, Y.3
-
21
-
-
33646432730
-
Mutation in the epsilon subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct5) gene causes autosomal recessive mutilating sensory neuropathy with spastic paraplegia
-
Bouhouche A, Benomar A, Bouslam N et al (2006) Mutation in the epsilon subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct5) gene causes autosomal recessive mutilating sensory neuropathy with spastic paraplegia. J Med Genet 43:441-443
-
(2006)
J Med Genet
, vol.43
, pp. 441-443
-
-
Bouhouche, A.1
Benomar, A.2
Bouslam, N.3
-
22
-
-
46149118689
-
The Hsp60-(p. V98I) mutation associated with hereditary spastic paraplegia SPG13 compromises chaperonin function both in vitro and in vivo
-
Bross P, Naundrup S, Hansen J et al (2008) The Hsp60-(p. V98I) mutation associated with hereditary spastic paraplegia SPG13 compromises chaperonin function both in vitro and in vivo. J Biol Chem 283:15694-15700
-
(2008)
J Biol Chem
, vol.283
, pp. 15694-15700
-
-
Bross, P.1
Naundrup, S.2
Hansen, J.3
-
23
-
-
37249005420
-
Small heat shock protein Hsp27 is required for proper heart tube formation
-
Brown D D, Christine K S, Showell C et al (2007) Small heat shock protein Hsp27 is required for proper heart tube formation. Genesis 45:667-78
-
(2007)
Genesis
, vol.45
, pp. 667-678
-
-
Brown, D.D.1
Christine, K.S.2
Showell, C.3
-
24
-
-
0036849511
-
Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport
-
Brownlees J, Ackerley S, Grierson A J et al (2002) Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport. Hum Mol Genet 11:2837-44
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2837-2844
-
-
Brownlees, J.1
Ackerley, S.2
Grierson, A.J.3
-
25
-
-
0344507132
-
Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis
-
Bruening W, Roy J, Giasson B et al (1999) Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis. J Neurochem 72:693-699
-
(1999)
J Neurochem
, vol.72
, pp. 693-699
-
-
Bruening, W.1
Roy, J.2
Giasson, B.3
-
26
-
-
0034282104
-
Hsp27 negatively regulates cell death by interacting with cytochrome c
-
Bruey J M, Ducasse C, Bonniaud P et al (2000a) Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat Cell Biol 2:645-652
-
(2000)
Nat Cell Biol
, vol.2
, pp. 645-652
-
-
Bruey, J.M.1
Ducasse, C.2
Bonniaud, P.3
-
27
-
-
0034609765
-
Differential regulation of HSP27 oligomerization in tumor cells grown in vitro and in vivo
-
Bruey J M, Paul C, Fromentin A et al (2000b) Differential regulation of HSP27 oligomerization in tumor cells grown in vitro and in vivo. Oncogene 19:4855-4863
-
(2000)
Oncogene
, vol.19
, pp. 4855-4863
-
-
Bruey, J.M.1
Paul, C.2
Fromentin, A.3
-
28
-
-
33845655395
-
Recruitment of phosphorylated small heat shock protein Hsp27 to nuclear speckles without stress
-
Bryantsev A L, Chechenova M B and Shelden E A (2007) Recruitment of phosphorylated small heat shock protein Hsp27 to nuclear speckles without stress. Exp Cell Res 313:195-209
-
(2007)
Exp Cell Res
, vol.313
, pp. 195-209
-
-
Bryantsev, A.L.1
Chechenova, M.B.2
Shelden, E.A.3
-
29
-
-
0032586878
-
Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperonelike function
-
Bova M P, Yaron O, Huang Q et al (1999) Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperonelike function. Proc Natl Acad Sci U S A 96:6137-42
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 6137-6142
-
-
Bova, M.P.1
Yaron, O.2
Huang, Q.3
-
30
-
-
38349105324
-
HspB8 chaperone activity toward poly (Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy
-
Carra S, Seguin S J, Lambert H et al (2008a) HspB8 chaperone activity toward poly (Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy. J Biol Chem 283:1437-1444
-
(2008)
J Biol Chem
, vol.283
, pp. 1437-1444
-
-
Carra, S.1
Seguin, S.J.2
Lambert, H.3
-
31
-
-
38949184241
-
HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy
-
Carra S, Seguin S J and Landry J (2008b) HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy. Autophagy 4:237-239
-
(2008)
Autophagy
, vol.4
, pp. 237-239
-
-
Carra, S.1
Seguin, S.J.2
Landry, J.3
-
32
-
-
21244489544
-
HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells
-
Carra S, Sivilotti M, Chavez Zobel A T et al (2005) HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells. Hum Mol Genet 14:1659-1669
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1659-1669
-
-
Carra, S.1
Sivilotti, M.2
Chavez Zobel, A.T.3
-
33
-
-
0034512869
-
The interaction of HSP27 with Daxx identifies a potential regulatory role of HSP27 in Fas-induced apoptosis
-
Charette S J and Landry J (2000) The interaction of HSP27 with Daxx identifies a potential regulatory role of HSP27 in Fas-induced apoptosis. Ann N Y Acad Sci 926:126-131
-
(2000)
Ann N Y Acad Sci
, vol.926
, pp. 126-131
-
-
Charette, S.J.1
Landry, J.2
-
34
-
-
6344237101
-
Effects of hypoxia on stress proteins in the piglet brain at birth
-
Chiral M, Grongnet J F, Plumier J C, David JC (2004) Effects of hypoxia on stress proteins in the piglet brain at birth. Pediatr Res 56:775-782
-
(2004)
Pediatr Res
, vol.56
, pp. 775-782
-
-
Chiral, M.1
Grongnet, J.F.2
Plumier, J.C.3
David, J.C.4
-
35
-
-
46449127758
-
Distal hereditary motor neuropathy in Korean patients with a small heat shock protein 27 mutation
-
Chung K W, Kim S B, Cho S Y et al (2008) Distal hereditary motor neuropathy in Korean patients with a small heat shock protein 27 mutation. Exp Mol Med 40:304-312
-
(2008)
Exp Mol Med
, vol.40
, pp. 304-312
-
-
Chung, K.W.1
Kim, S.B.2
Cho, S.Y.3
-
37
-
-
33749184049
-
Up-regulation of heat shock protein HSP 20 in the hippocampus as an early response to hypoxia of the newborn
-
David J C, Boelens W C, Grongnet J F (2006) Up-regulation of heat shock protein HSP 20 in the hippocampus as an early response to hypoxia of the newborn. J Neurochem 99:570-581
-
(2006)
J Neurochem
, vol.99
, pp. 570-581
-
-
David, J.C.1
Boelens, W.C.2
Grongnet, J.F.3
-
38
-
-
0027472047
-
Evolution of the alpha-crystallin/small heat-shock protein family
-
de Jong W W, Leunissen J A and Voorter C E (1993) Evolution of the alpha-crystallin/small heat-shock protein family. Mol Biol Evol 10:103-126
-
(1993)
Mol Biol Evol
, vol.10
, pp. 103-126
-
-
De Jong, W.W.1
Leunissen, J.A.2
Voorter, C.E.3
-
39
-
-
8644246567
-
Mimicking phosphorylation of the small heat-shock protein alphaB-crystallin recruits the F-box protein FBX4 to nuclear SC35 speckles
-
den Engelsman J, Bennink E J, Doerwald L et al (2004) Mimicking phosphorylation of the small heat-shock protein alphaB-crystallin recruits the F-box protein FBX4 to nuclear SC35 speckles. Eur J Biochem 271:4195-203
-
(2004)
Eur J Biochem
, vol.271
, pp. 4195-4203
-
-
Den Engelsman, J.1
Bennink, E.J.2
Doerwald, L.3
-
40
-
-
27744461695
-
Nuclear import of {alpha}B-crystallin is phosphorylation-dependent and hampered by hyperphosphorylation of the myopathy-related mutant R120G
-
den Engelsman J, Gerrits D, de Jong W W et al (2005) Nuclear import of {alpha}B-crystallin is phosphorylation-dependent and hampered by hyperphosphorylation of the myopathy-related mutant R120G. J Biol Chem 280:37139-37148
-
(2005)
J Biol Chem
, vol.280
, pp. 37139-37148
-
-
Den Engelsman, J.1
Gerrits, D.2
De Jong, W.W.3
-
41
-
-
34548239171
-
Genetic variant in the HSPB1 promotor region impairs the HSP27 stress response
-
Dierick I, Irobi J, Janssens S et al (2007) Genetic variant in the HSPB1 promotor region impairs the HSP27 stress response. Hum Mutat 28:830
-
(2007)
Hum Mutat
, vol.28
, pp. 830
-
-
Dierick, I.1
Irobi, J.2
Janssens, S.3
-
42
-
-
44949255090
-
Relative contribution of mutations in genes for autosomal dominant distal hereditary motor neuropathies: A genotype-phenotype correlation study
-
Dierick I, Baets J, Irobi J et al (2008) Relative contribution of mutations in genes for autosomal dominant distal hereditary motor neuropathies: a genotype-phenotype correlation study. Brain 131:1217-27
-
(2008)
Brain
, vol.131
, pp. 1217-1227
-
-
Dierick, I.1
Baets, J.2
Irobi, J.3
-
43
-
-
0030724879
-
AlphaB-crystallin interacts with intermediate filaments in response to stress
-
Djabali K, de Nechaud B, Landon F et al (1997) AlphaB-crystallin interacts with intermediate filaments in response to stress. J Cell Sci 110(Pt 21):2759-2769
-
(1997)
J Cell Sci
, vol.110
, pp. 2759-2769
-
-
Djabali, K.1
De Nechaud, B.2
Landon, F.3
-
44
-
-
33746485560
-
The Alexander disease-causing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alpha B-crystallin and HSP27
-
Der Perng M, Su M, Wen S F et al (2006) The Alexander disease-causing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alpha B-crystallin and HSP27. Am J Hum Genet 79:197-213
-
(2006)
Am J Hum Genet
, vol.79
, pp. 197-213
-
-
Der Perng, M.1
Su, M.2
Wen, S.F.3
-
45
-
-
0033858377
-
Demyelination and axonal dystrophy in alpha A-crystallin transgenic mice
-
De Rijk E P, Van Rijk A F, Van Esch E et al (2000) Demyelination and axonal dystrophy in alpha A-crystallin transgenic mice. Int J Exp Pathol 81:271-82
-
(2000)
Int J Exp Pathol
, vol.81
, pp. 271-282
-
-
De Rijk, E.P.1
Van Rijk, A.F.2
Van Esch, E.3
-
46
-
-
2642563501
-
Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy
-
Evgrafov O V, Mersiyanova I, Irobi J et al (2004) Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Nat Genet 36:602-606
-
(2004)
Nat Genet
, vol.36
, pp. 602-606
-
-
Evgrafov, O.V.1
Mersiyanova, I.2
Irobi, J.3
-
47
-
-
26844557815
-
Interactions of HSP22 (HSPB8) with HSP20, alphaB-crystallin, and HSPB3
-
Fontaine J M, Sun X, Benndorf R et al (2005) Interactions of HSP22 (HSPB8) with HSP20, alphaB-crystallin, and HSPB3. Biochem Biophys Res Commun 337:1006-11
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 1006-1011
-
-
Fontaine, J.M.1
Sun, X.2
Benndorf, R.3
-
48
-
-
33845600705
-
Abnormal small heat shock protein interactions involving neuropathy-associated HSP22 (HSPB8) mutants
-
Fontaine J M, Sun X, Hoppe A D et al (2006) Abnormal small heat shock protein interactions involving neuropathy-associated HSP22 (HSPB8) mutants. FASEB J 20:2168-2170
-
(2006)
FASEB J
, vol.20
, pp. 2168-2170
-
-
Fontaine, J.M.1
Sun, X.2
Hoppe, A.D.3
-
49
-
-
0037047163
-
Interaction of intracellular beta amyloid peptide with chaperone proteins
-
Fonte V, Kapulkin V, Taft A et al (2002) Interaction of intracellular beta amyloid peptide with chaperone proteins. Proc Natl Acad Sci U S A 99:9439-9444
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 9439-9444
-
-
Fonte, V.1
Kapulkin, V.2
Taft, A.3
-
50
-
-
0037336078
-
Alteration of protein-protein interactions of congenital cataract crystallin mutants
-
Fu L and Liang J J (2003a) Alteration of protein-protein interactions of congenital cataract crystallin mutants. Invest Ophthalmol Vis Sci 44:1155-1159
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 1155-1159
-
-
Fu, L.1
Liang, J.J.2
-
51
-
-
0037459183
-
Enhanced stability of alpha B-crystallin in the presence of small heat shock protein Hsp27
-
Fu L and Liang J J (2003b) Enhanced stability of alpha B-crystallin in the presence of small heat shock protein Hsp27. Biochem Biophys Res Commun 302:710-714
-
(2003)
Biochem Biophys Res Commun
, vol.302
, pp. 710-714
-
-
Fu, L.1
Liang, J.J.2
-
52
-
-
0032559341
-
A structural scaffolding of intermediate filaments in health and disease
-
Fuchs E, Cleveland D W (1998) A structural scaffolding of intermediate filaments in health and disease. Science 279:514-9
-
(1998)
Science
, vol.279
, pp. 514-519
-
-
Fuchs, E.1
Cleveland, D.W.2
-
54
-
-
0030272135
-
Familial desmin-related myopathies and cardiomyopathies-from myopathology to molecular and clinical genetics. 36th European Neuromuscular Center (ENMC)-Sponsored International Workshop 20-22 October, 1995, Naarden, The Netherlands
-
Goebel H H, Fardeau M. Familial desmin-related myopathies and cardiomyopathies-from myopathology to molecular and clinical genetics. 36th European Neuromuscular Center (ENMC)-Sponsored International Workshop 20-22 October, 1995, Naarden, The Netherlands. Neuromuscul Disord 6:383-8
-
Neuromuscul Disord
, vol.6
, pp. 383-388
-
-
Goebel, H.H.1
Fardeau, M.2
-
55
-
-
0036558366
-
Structure and properties of small heat shock proteins (sHsp) and their interaction with cytoskeleton proteins
-
Gusev N B, Bogatcheva N V and Marston S B (2002) Structure and properties of small heat shock proteins (sHsp) and their interaction with cytoskeleton proteins. Biochemistry (Mosc) 67:511-519
-
(2002)
Biochemistry (Mosc)
, vol.67
, pp. 511-519
-
-
Gusev, N.B.1
Bogatcheva, N.V.2
Marston, S.B.3
-
56
-
-
0036241765
-
Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60
-
Hansen J J, Durr A, Cournu-Rebeix I et al (2002) Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60. Am J Hum Genet 70:1328-1332
-
(2002)
Am J Hum Genet
, vol.70
, pp. 1328-1332
-
-
Hansen, J.J.1
Durr, A.2
Cournu-Rebeix, I.3
-
58
-
-
27144448839
-
Some like it hot: The structure and function of small heat-shock proteins
-
Haslbeck M, Franzmann T, Weinfurtner D et al (2005) Some like it hot: the structure and function of small heat-shock proteins. Nat Struct Mol Biol 12:842-846
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 842-846
-
-
Haslbeck, M.1
Franzmann, T.2
Weinfurtner, D.3
-
59
-
-
0026483279
-
Alpha-crystallin can function as a molecular chaperone
-
Horwitz J (1992) Alpha-crystallin can function as a molecular chaperone. Proc Natl Acad Sci U S A 89:10449-10453
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10449-10453
-
-
Horwitz, J.1
-
60
-
-
0001140122
-
Inherited neuronal atrophy and degeneration predominantly of lower motor neurons
-
3rd Edition Dyck PJ, Thomas PK, Griffin JW, Low PA, Poduslo JF, eds
-
Harding A E (1993) Inherited neuronal atrophy and degeneration predominantly of lower motor neurons. In: Peripheral Neuropathy, 3rd Edition (Dyck PJ, Thomas PK, Griffin JW, Low PA, Poduslo JF, eds), pp 1051-1064
-
(1993)
Peripheral Neuropathy
, pp. 1051-1064
-
-
Harding, A.E.1
-
61
-
-
45549088083
-
Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism
-
Havasi A, Li Z, Wang Z et al (2008) Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism. J Biol Chem 283:12305-13
-
(2008)
J Biol Chem
, vol.283
, pp. 12305-12313
-
-
Havasi, A.1
Li, Z.2
Wang, Z.3
-
62
-
-
58149243285
-
Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2
-
Houlden H, Laura M, Wavrant-De Vrièze F et al (2008) Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2. Neurology 71:1660-8
-
(2008)
Neurology
, vol.71
, pp. 1660-1668
-
-
Houlden, H.1
Laura, M.2
Wavrant-De Vrièze, F.3
-
63
-
-
33744732089
-
A transgenic mouse model for human autosomal dominant cataract
-
Hsu C D, Kymes S, Petrash J M (2006) A transgenic mouse model for human autosomal dominant cataract. Invest Ophthalmol Vis Sci 47:2036-44
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 2036-2044
-
-
Hsu, C.D.1
Kymes, S.2
Petrash, J.M.3
-
64
-
-
35348844114
-
Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption
-
Huang L, Min J N, Masters S et al (2007) Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption. Genesis 45:487-501
-
(2007)
Genesis
, vol.45
, pp. 487-501
-
-
Huang, L.1
Min, J.N.2
Masters, S.3
-
66
-
-
0020063988
-
Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin
-
Ingolia T D and Craig E A (1982) Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin. Proc Natl Acad Sci U S A 79:2360-2364
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, pp. 2360-2364
-
-
Ingolia, T.D.1
Craig, E.A.2
-
67
-
-
33745235798
-
Unraveling the genetics of distal hereditary motor neuronopathies
-
Irobi J, Dierick I, Jordanova A et al (2006) Unraveling the genetics of distal hereditary motor neuronopathies. Neuromolecular Med 8:131-146
-
(2006)
Neuromolecular Med
, vol.8
, pp. 131-146
-
-
Irobi, J.1
Dierick, I.2
Jordanova, A.3
-
68
-
-
2642539919
-
Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy
-
Irobi J, Van Impe K, Seeman P et al (2004) Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. Nat Genet 36:597-601
-
(2004)
Nat Genet
, vol.36
, pp. 597-601
-
-
Irobi, J.1
Van Impe, K.2
Seeman, P.3
-
69
-
-
0034960562
-
Regulation of the levels of small heat-shock proteins during differentiation of C2C12 cells
-
Ito H, Kamei K, Iwamoto I et al (2001) Regulation of the levels of small heat-shock proteins during differentiation of C2C12 cells. Exp Cell Res 266:213-221
-
(2001)
Exp Cell Res
, vol.266
, pp. 213-221
-
-
Ito, H.1
Kamei, K.2
Iwamoto, I.3
-
70
-
-
0038723738
-
Hsp27 suppresses the formation of inclusion bodies induced by expression of R120G alpha B-crystallin, a cause of desmin-related myopathy
-
Ito H, Kamei K, Iwamoto I et al (2003) Hsp27 suppresses the formation of inclusion bodies induced by expression of R120G alpha B-crystallin, a cause of desmin-related myopathy. Cell Mol Life Sci 60:1217-1223
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1217-1223
-
-
Ito, H.1
Kamei, K.2
Iwamoto, I.3
-
71
-
-
58149299834
-
A clinical phenotype of distal hereditary motor neuronopathy type II with a novel HSPB1 mutation
-
Ikeda Y, Abe A, Ishida C et al (2008) A clinical phenotype of distal hereditary motor neuronopathy type II with a novel HSPB1 mutation. J Neurol Sci 277:9-12
-
(2008)
J Neurol Sci
, vol.277
, pp. 9-12
-
-
Ikeda, Y.1
Abe, A.2
Ishida, C.3
-
72
-
-
0032768772
-
Heat shock proteins as cellular lifeguards
-
Jäättelä M (1999a) Heat shock proteins as cellular lifeguards. Ann Med 31:261-271
-
(1999)
Ann Med
, vol.31
, pp. 261-271
-
-
Jäättelä, M.1
-
73
-
-
0038668000
-
Escaping cell death: Survival proteins in cancer
-
Jäättelä M (1999b) Escaping cell death: survival proteins in cancer. Exp Cell Res 248:30-43
-
(1999)
Exp Cell Res
, vol.248
, pp. 30-43
-
-
Jäättelä, M.1
-
74
-
-
0027391629
-
Small heat shock proteins are molecular chaperones
-
Jakob U, Gaestel M, Engel K et al (1993) Small heat shock proteins are molecular chaperones. J Biol Chem 268:1517-1520
-
(1993)
J Biol Chem
, vol.268
, pp. 1517-1520
-
-
Jakob, U.1
Gaestel, M.2
Engel, K.3
-
75
-
-
41149089652
-
Asymmetrical late onset motor neuropathy associated with a novel mutation in the small heat shock protein HSPB1 (HSP27)
-
James P A, Rankin J and Talbot K (2008) Asymmetrical late onset motor neuropathy associated with a novel mutation in the small heat shock protein HSPB1 (HSP27). J Neurol Neurosurg Psychiatry 79:461-463
-
(2008)
J Neurol Neurosurg Psychiatry
, vol.79
, pp. 461-463
-
-
James, P.A.1
Rankin, J.2
Talbot, K.3
-
76
-
-
0346665904
-
Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss
-
Kalwy S A, Akbar M T, Coffin R S et al (2003) Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss. Brain Res Mol Brain Res 111:91-103
-
(2003)
Brain Res Mol Brain Res
, vol.111
, pp. 91-103
-
-
Kalwy, S.A.1
Akbar, M.T.2
Coffin, R.S.3
-
77
-
-
35448989800
-
Effect of mutations in the beta5-beta7 loop on the structure and properties of human small heat shock protein HSP22 (HspB8, H11)
-
Kasakov A S, Bukach O V, Seit-Nebi A S et al (2007) Effect of mutations in the beta5-beta7 loop on the structure and properties of human small heat shock protein HSP22 (HspB8, H11). FEBS J 274:5628-5642
-
(2007)
FEBS J
, vol.274
, pp. 5628-5642
-
-
Kasakov, A.S.1
Bukach, O.V.2
Seit-Nebi, A.S.3
-
78
-
-
0033822064
-
Mutations in MKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome
-
Katsanis N, Beales P L, Woods M O et al (2000) Mutations in MKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome. Nat Genet 26:67-70
-
(2000)
Nat Genet
, vol.26
, pp. 67-70
-
-
Katsanis, N.1
Beales, P.L.2
Woods, M.O.3
-
79
-
-
0035844174
-
The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation
-
Kamradt M C, Chen F, Cryns V L (2001) The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation. J Biol Chem 276:16059-63
-
(2001)
J Biol Chem
, vol.276
, pp. 16059-16063
-
-
Kamradt, M.C.1
Chen, F.2
Cryns, V.L.3
-
80
-
-
0037064065
-
The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation
-
Kamradt M C, Chen F, Sam S et al (2002) The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. J Biol Chem 277:38731-6
-
(2002)
J Biol Chem
, vol.277
, pp. 38731-38736
-
-
Kamradt, M.C.1
Chen, F.2
Sam, S.3
-
81
-
-
20144374696
-
The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3
-
Kamradt M C, Lu M, Werner M E et al (2005) The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3. J Biol Chem 280:11059-66
-
(2005)
J Biol Chem
, vol.280
, pp. 11059-11066
-
-
Kamradt, M.C.1
Lu, M.2
Werner, M.E.3
-
82
-
-
26944431622
-
Small heat shock protein 27 mutation in a Japanese patient with distal hereditary motor neuropathy
-
Kijima K, Numakura C, Goto T et al (2005) Small heat shock protein 27 mutation in a Japanese patient with distal hereditary motor neuropathy. J Hum Genet 50:473-476
-
(2005)
J Hum Genet
, vol.50
, pp. 473-476
-
-
Kijima, K.1
Numakura, C.2
Goto, T.3
-
83
-
-
1342292267
-
Crystal structure of a small heat-shock protein
-
Kim K K, Kim R and Kim S H (1998) Crystal structure of a small heat-shock protein. Nature 394:595-599
-
(1998)
Nature
, vol.394
, pp. 595-599
-
-
Kim, K.K.1
Kim, R.2
Kim, S.H.3
-
84
-
-
33748892808
-
Structure and properties of K141E mutant of small heat shock protein HSP22 (HspB8, H11) that is expressed in human neuromuscular disorders
-
Kim M V, Kasakov A S, Seit-Nebi A S et al (2006) Structure and properties of K141E mutant of small heat shock protein HSP22 (HspB8, H11) that is expressed in human neuromuscular disorders. Arch Biochem Biophys 454:32-41
-
(2006)
Arch Biochem Biophys
, vol.454
, pp. 32-41
-
-
Kim, M.V.1
Kasakov, A.S.2
Seit-Nebi, A.S.3
-
85
-
-
0028059718
-
Increased expression of the M (r) 27, 000 heat shock protein (hsp27) in in vitro differentiated normal human keratinocytes
-
Kindås-Mügge I and Trautinger F (1994) Increased expression of the M (r) 27, 000 heat shock protein (hsp27) in in vitro differentiated normal human keratinocytes. Cell Growth Differ 5:777-781
-
(1994)
Cell Growth Differ
, vol.5
, pp. 777-781
-
-
Kindås-Mügge, I.1
Trautinger, F.2
-
86
-
-
33751059033
-
Myofibrillar myopathy with congenital cataract and skeletal anomalies without mutations in the desmin, alphaB-crystallin, myotilin, LMNA or SEPN1 genes
-
Kostera-Pruszczyk A, Goudeau B, Ferreiro A et al (2006) Myofibrillar myopathy with congenital cataract and skeletal anomalies without mutations in the desmin, alphaB-crystallin, myotilin, LMNA or SEPN1 genes. Neuromuscul Disord 16:759-62
-
(2006)
Neuromuscul Disord
, vol.16
, pp. 759-762
-
-
Kostera-Pruszczyk, A.1
Goudeau, B.2
Ferreiro, A.3
-
87
-
-
34248199267
-
Molecular chaperones: The modular evolution of cellular networks
-
Korcsmáros T, Kovács I A, Szalay M S et al (2007) Molecular chaperones: the modular evolution of cellular networks. J Biosci 32:441-6
-
(2007)
J Biosci
, vol.32
, pp. 441-446
-
-
Korcsmáros, T.1
Kovács, I.A.2
Szalay, M.S.3
-
88
-
-
33746312670
-
Role of heat shock response and Hsp27 in mutant SOD1-dependent cell death
-
Krishnan J, Lemmens R and Robberecht W (2006) Role of heat shock response and Hsp27 in mutant SOD1-dependent cell death. Exp Neurol 200:301-310
-
(2006)
Exp Neurol
, vol.200
, pp. 301-310
-
-
Krishnan, J.1
Lemmens, R.2
Robberecht, W.3
-
89
-
-
49549120206
-
Overexpression of Hsp27 does not influence disease in the mutant SOD1 (G93A) mouse model of amyotrophic lateral sclerosis
-
Krishnan J, Vannuvel K, Andries M et al (2008) Overexpression of Hsp27 does not influence disease in the mutant SOD1 (G93A) mouse model of amyotrophic lateral sclerosis. J Neurochem 106:2170-2183
-
(2008)
J Neurochem
, vol.106
, pp. 2170-2183
-
-
Krishnan, J.1
Vannuvel, K.2
Andries, M.3
-
90
-
-
0036359488
-
Hsp27 in the nervous system: Expression in pathophysiology and in the aging brain
-
Krueger-Naug A M, Plumier J C, Hopkins D A et al (2002) Hsp27 in the nervous system: expression in pathophysiology and in the aging brain. Prog Mol Subcell Biol 28:235-251
-
(2002)
Prog Mol Subcell Biol
, vol.28
, pp. 235-251
-
-
Krueger-Naug, A.M.1
Plumier, J.C.2
Hopkins, D.A.3
-
91
-
-
44149104599
-
Heat shock proteins: Essential proteins for apoptosis regulation
-
Lanneau D, Brunet M, Frisan E et al (2008) Heat shock proteins: essential proteins for apoptosis regulation. J Cell Mol Med 12:743-61
-
(2008)
J Cell Mol Med
, vol.12
, pp. 743-761
-
-
Lanneau, D.1
Brunet, M.2
Frisan, E.3
-
92
-
-
0033515597
-
HSP27 multimerization mediated by phosphorylation-sensitive intermolecular interactions at the amino terminus
-
Lambert H, Charette S J, Bernier A F et al (1999) HSP27 multimerization mediated by phosphorylation-sensitive intermolecular interactions at the amino terminus. J Biol Chem 274:9378-9385
-
(1999)
J Biol Chem
, vol.274
, pp. 9378-9385
-
-
Lambert, H.1
Charette, S.J.2
Bernier, A.F.3
-
93
-
-
0027482463
-
Modulation of actin microfilament dynamics and fluid phase pinocytosis by phosphorylation of heat shock protein 27
-
Lavoie J N, Hickey E, Weber L A et al (1993) Modulation of actin microfilament dynamics and fluid phase pinocytosis by phosphorylation of heat shock protein 27. J Biol Chem 268:24210-4
-
(1993)
J Biol Chem
, vol.268
, pp. 24210-24214
-
-
Lavoie, J.N.1
Hickey, E.2
Weber, L.A.3
-
94
-
-
0028924759
-
Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27
-
Lavoie J N, Lambert H, Hickey E et al (1995) Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27. Mol Cell Biol 15:505-16
-
(1995)
Mol Cell Biol
, vol.15
, pp. 505-516
-
-
Lavoie, J.N.1
Lambert, H.2
Hickey, E.3
-
95
-
-
0027982174
-
Alpha-B crystallin in the normal human myocardium and cardiac conducting system
-
Leach I H, Tsang M L, Church R J et al (1994) Alpha-B crystallin in the normal human myocardium and cardiac conducting system. J Pathol 173:255-260
-
(1994)
J Pathol
, vol.173
, pp. 255-260
-
-
Leach, I.H.1
Tsang, M.L.2
Church, R.J.3
-
96
-
-
10744228985
-
Hereditary sensory neuropathy is caused by a mutation in the delta subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct4) gene
-
Lee M J, Stephenson D A, Groves M J et al (2003) Hereditary sensory neuropathy is caused by a mutation in the delta subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct4) gene. Hum Mol Genet 12:1917-1925
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1917-1925
-
-
Lee, M.J.1
Stephenson, D.A.2
Groves, M.J.3
-
97
-
-
0022571569
-
Small heat shock proteins of Drosophila associate with the cytoskeleton
-
Leicht B G, Biessmann H, Palter K B et al (1986) Small heat shock proteins of Drosophila associate with the cytoskeleton. Proc Natl Acad Sci U S A 83:90-94
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 90-94
-
-
Leicht, B.G.1
Biessmann, H.2
Palter, K.B.3
-
98
-
-
34848908677
-
The role of the conserved COOH-terminal triad in alphaA-crystallin aggregation and functionality
-
Li Y, Schmitz K R, Salerno J C et al (2007) The role of the conserved COOH-terminal triad in alphaA-crystallin aggregation and functionality. Mol Vis 13:1758-68
-
(2007)
Mol Vis
, vol.13
, pp. 1758-1768
-
-
Li, Y.1
Schmitz, K.R.2
Salerno, J.C.3
-
100
-
-
0031934121
-
Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA
-
Litt M, Kramer P, LaMorticella D M et al (1998) Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA. Hum Mol Genet 7:471-474
-
(1998)
Hum Mol Genet
, vol.7
, pp. 471-474
-
-
Litt, M.1
Kramer, P.2
LaMorticella, D.M.3
-
101
-
-
18844444198
-
Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis
-
Liu J, Shinobu L A, Ward C M et al (2005) Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis. J Neurochem 93:875-882
-
(2005)
J Neurochem
, vol.93
, pp. 875-882
-
-
Liu, J.1
Shinobu, L.A.2
Ward, C.M.3
-
102
-
-
33748109601
-
Identification of a CRYAB mutation associated with autosomal dominant posterior polar cataract in a Chinese family
-
Liu M, Ke T, Wang Z et al (2006a) Identification of a CRYAB mutation associated with autosomal dominant posterior polar cataract in a Chinese family. Invest Ophthalmol Vis Sci 47:3461-3466
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 3461-3466
-
-
Liu, M.1
Ke, T.2
Wang, Z.3
-
103
-
-
33846297971
-
Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis
-
Liu S, Li J, Tao Y et al (2007) Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis. Biochem Biophys Res Commun 354:109-114
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 109-114
-
-
Liu, S.1
Li, J.2
Tao, Y.3
-
104
-
-
33645401324
-
A novel alphaB-crystallin mutation associated with autosomal dominant congenital lamellar cataract
-
Liu Y, Zhang X, Luo L et al (2006b) A novel alphaB-crystallin mutation associated with autosomal dominant congenital lamellar cataract. Invest Ophthalmol Vis Sci 47:1069-1075
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 1069-1075
-
-
Liu, Y.1
Zhang, X.2
Luo, L.3
-
105
-
-
35549006420
-
Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease
-
Lobsiger C S and Cleveland D W (2007) Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease. Nat Neurosci 10:1355-1360
-
(2007)
Nat Neurosci
, vol.10
, pp. 1355-1360
-
-
Lobsiger, C.S.1
Cleveland, D.W.2
-
106
-
-
0033664329
-
The distribution of heat shock proteins in the nervous system of the unstressed mouse embryo suggests a role in neuronal and non-neuronal differentiation
-
Loones M T, Chang Y and Morange M (2000) The distribution of heat shock proteins in the nervous system of the unstressed mouse embryo suggests a role in neuronal and non-neuronal differentiation. Cell Stress Chaperones 5:291-305
-
(2000)
Cell Stress Chaperones
, vol.5
, pp. 291-305
-
-
Loones, M.T.1
Chang, Y.2
Morange, M.3
-
107
-
-
15944397596
-
Effects of hypoxia on stress proteins in the piglet heart at birth
-
Louapre P, Grongnet J F, Tanguay R M et al (2005) Effects of hypoxia on stress proteins in the piglet heart at birth. Cell Stress Chaperones 10:17-23
-
(2005)
Cell Stress Chaperones
, vol.10
, pp. 17-23
-
-
Louapre, P.1
Grongnet, J.F.2
Tanguay, R.M.3
-
108
-
-
3142692478
-
Decrease of Hsp25 protein expression precedes degeneration of motoneurons in ALS-SOD1 mice
-
Maatkamp A, Vlug A, Haasdijk E et al (2004) Decrease of Hsp25 protein expression precedes degeneration of motoneurons in ALS-SOD1 mice. Eur J Neurosci 20:14-28
-
(2004)
Eur J Neurosci
, vol.20
, pp. 14-28
-
-
Maatkamp, A.1
Vlug, A.2
Haasdijk, E.3
-
109
-
-
34447548232
-
Molecular chaperones: Multiple functions, pathologies, and potential applications
-
Macario A J and Conway de Macario E (2007) Molecular chaperones: multiple functions, pathologies, and potential applications. Front Biosci 12:2588-2600
-
(2007)
Front Biosci
, vol.12
, pp. 2588-2600
-
-
Macario, A.J.1
Conway De Macario, E.2
-
110
-
-
0242287938
-
Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q
-
Mackay D S, Andley U P and Shiels A (2003) Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q. Eur J Hum Genet 11:784-793
-
(2003)
Eur J Hum Genet
, vol.11
, pp. 784-793
-
-
Mackay, D.S.1
Andley, U.P.2
Shiels, A.3
-
111
-
-
46149097136
-
Mitochondrial hsp60 chaperonopathy causes an autosomal-recessive neurodegenerative disorder linked to brain hypomyelination and leukodystrophy
-
Magen D, Georgopoulos C, Bross P et al (2008) Mitochondrial hsp60 chaperonopathy causes an autosomal-recessive neurodegenerative disorder linked to brain hypomyelination and leukodystrophy. Am J Hum Genet 83:30-42
-
(2008)
Am J Hum Genet
, vol.83
, pp. 30-42
-
-
Magen, D.1
Georgopoulos, C.2
Bross, P.3
-
112
-
-
33644874959
-
Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy
-
Maloyan A, Sanbe A, Osinska H et al (2005) Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy. Circulation 112:3451-3461
-
(2005)
Circulation
, vol.112
, pp. 3451-3461
-
-
Maloyan, A.1
Sanbe, A.2
Osinska, H.3
-
113
-
-
0031454881
-
Hsp27 as a switch between differentiation and apoptosis in murine embryonic stem cells
-
Mehlen P, Mehlen A, Godet J et al (1997) Hsp27 as a switch between differentiation and apoptosis in murine embryonic stem cells. J Biol Chem 272:31657-31665
-
(1997)
J Biol Chem
, vol.272
, pp. 31657-31665
-
-
Mehlen, P.1
Mehlen, A.2
Godet, J.3
-
114
-
-
0033911099
-
A new variant of Charcot-Marie-Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene
-
Mersiyanova I V, Perepelov A V, Polyakov A V et al (2000) A new variant of Charcot-Marie-Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene. Am J Hum Genet 67:37-46
-
(2000)
Am J Hum Genet
, vol.67
, pp. 37-46
-
-
Mersiyanova, I.V.1
Perepelov, A.V.2
Polyakov, A.V.3
-
115
-
-
0031469912
-
Hsp70 and Hsp40 chaperone activities in the cytoplasm and the nucleus of mammalian cells
-
Michels A A, Kanon B, Konings A W et al (1997) Hsp70 and Hsp40 chaperone activities in the cytoplasm and the nucleus of mammalian cells. J Biol Chem 272:33283-9
-
(1997)
J Biol Chem
, vol.272
, pp. 33283-33289
-
-
Michels, A.A.1
Kanon, B.2
Konings, A.W.3
-
116
-
-
0031297298
-
The heat-shock response: Regulation and function of heat-shock proteins and molecular chaperones
-
Morimoto R I, Kline M P, Bimston D N et al (1997) The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones. Essays Biochem 32:17-29
-
(1997)
Essays Biochem
, vol.32
, pp. 17-29
-
-
Morimoto, R.I.1
Kline, M.P.2
Bimston, D.N.3
-
117
-
-
0036556697
-
Actin cytoskeleton and small heat shock proteins: How do they interact?
-
Mounier N and Arrigo A P (2002) Actin cytoskeleton and small heat shock proteins: how do they interact? Cell Stress Chaperones 7:167-176
-
(2002)
Cell Stress Chaperones
, vol.7
, pp. 167-176
-
-
Mounier, N.1
Arrigo, A.P.2
-
118
-
-
0032477726
-
ATP-enhanced molecular chaperone functions of the small heat shock protein human alphaB crystallin
-
Muchowski P J and Clark J I (1998) ATP-enhanced molecular chaperone functions of the small heat shock protein human alphaB crystallin. Proc Natl Acad Sci U S A 95:1004-1009
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1004-1009
-
-
Muchowski, P.J.1
Clark, J.I.2
-
119
-
-
0033522885
-
Site-directed mutations within the core "alphacrystallin" domain of the small heat-shock protein, human alphaB-crystallin, decrease molecular chaperone functions
-
Muchowski P J, Wu G J, Liang J J, et al (1999) Site-directed mutations within the core "alphacrystallin" domain of the small heat-shock protein, human alphaB-crystallin, decrease molecular chaperone functions. J Mol Biol 289:397-411
-
(1999)
J Mol Biol
, vol.289
, pp. 397-411
-
-
Muchowski, P.J.1
Wu, G.J.2
Liang, J.J.3
-
120
-
-
0028176579
-
Chaperone activity of alpha-crystallins modulates intermediate filament assembly
-
Nicholl I D, Quinlan R A (1994) Chaperone activity of alpha-crystallins modulates intermediate filament assembly. EMBO J 13:945-53
-
(1994)
EMBO J
, vol.13
, pp. 945-953
-
-
Nicholl, I.D.1
Quinlan, R.A.2
-
121
-
-
0035834122
-
Dynamic changes in the localization of thermally unfolded nuclear proteins associated with chaperone-dependent protection
-
Nollen E A, Salomons F A, Brunsting J F et al (2001) Dynamic changes in the localization of thermally unfolded nuclear proteins associated with chaperone-dependent protection. Proc Natl Acad Sci U S A 98:12038-43
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 12038-12043
-
-
Nollen, E.A.1
Salomons, F.A.2
Brunsting, J.F.3
-
122
-
-
33751216491
-
Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation
-
Outeiro T F, Klucken J, Strathearn K E et al (2006) Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation. Biochem Biophys Res Commun 351:631-638
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 631-638
-
-
Outeiro, T.F.1
Klucken, J.2
Strathearn, K.E.3
-
123
-
-
0043133793
-
HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation
-
Parcellier A, Schmitt E, Gurbuxani S et al (2003) HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation. Mol Cell Biol 23:5790-5802
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5790-5802
-
-
Parcellier, A.1
Schmitt, E.2
Gurbuxani, S.3
-
124
-
-
33747605320
-
Molecular biology of amyotrophic lateral sclerosis: Insights from genetics
-
Pasinelli P and Brown R H (2006) Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat Rev Neurosci 7:710-723
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 710-723
-
-
Pasinelli, P.1
Brown, R.H.2
-
125
-
-
16544382615
-
The IXI/V motif in the C-terminal extension of alpha-crystallins: Alternative interactions and oligomeric assemblies
-
Pasta S Y, Raman B, Ramakrishna T et al (2004) The IXI/V motif in the C-terminal extension of alpha-crystallins: alternative interactions and oligomeric assemblies. Mol Vis 10:655-662
-
(2004)
Mol Vis
, vol.10
, pp. 655-662
-
-
Pasta, S.Y.1
Raman, B.2
Ramakrishna, T.3
-
126
-
-
17044403380
-
Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells
-
Patel Y J, Payne Smith M D, de Belleroche J et al (2005) Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells. Brain Res Mol Brain Res 134:256-274
-
(2005)
Brain Res Mol Brain Res
, vol.134
, pp. 256-274
-
-
Patel, Y.J.1
Payne Smith, M.D.2
De Belleroche, J.3
-
127
-
-
0032818827
-
Intermediate filament interactions can be altered by HSP27 and alphaB-crystallin
-
Perng M D, Cairns L, van den I P et al (1999) Intermediate filament interactions can be altered by HSP27 and alphaB-crystallin. J Cell Sci 112(Pt 13):2099-2112
-
(1999)
J Cell Sci
, vol.112
, pp. 2099-2112
-
-
Perng, M.D.1
Cairns, L.2
Van Den, I.P.3
-
128
-
-
2342455798
-
Desmin aggregate formation by R120G alphaB-crystallin is caused by altered filament interactions and is dependent upon network status in cells
-
Perng M D, Wen S F, van den I P et al (2004) Desmin aggregate formation by R120G alphaB-crystallin is caused by altered filament interactions and is dependent upon network status in cells. Mol Biol Cell 15:2335-2346
-
(2004)
Mol Biol Cell
, vol.15
, pp. 2335-2346
-
-
Perng, M.D.1
Wen, S.F.2
Van Den, I.P.3
-
129
-
-
34247245632
-
Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease
-
Perrin V, Régulier E, Abbas-Terki T et al (2007) Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease. Mol Ther 15:903-911
-
(2007)
Mol Ther
, vol.15
, pp. 903-911
-
-
Perrin, V.1
Régulier, E.2
Abbas-Terki, T.3
-
131
-
-
5444267945
-
Phenotypic analysis of neurofilament light gene mutations linked to Charcot-Marie-Tooth disease in cell culture models
-
Perez-Olle R, Jones S T, Liem R K (2004) Phenotypic analysis of neurofilament light gene mutations linked to Charcot-Marie-Tooth disease in cell culture models. Hum Mol Genet 13:2207-20
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2207-2220
-
-
Perez-Olle, R.1
Jones, S.T.2
Liem, R.K.3
-
132
-
-
18844446126
-
Mutations in the neurofilament light gene linked to Charcot-Marie-Tooth disease cause defects in transport
-
Pérez-Ollé R, López-Toledano M A, Goryunov D et al (2005) Mutations in the neurofilament light gene linked to Charcot-Marie-Tooth disease cause defects in transport. J Neurochem 93:861-74
-
(2005)
J Neurochem
, vol.93
, pp. 861-874
-
-
Pérez-Ollé, R.1
López-Toledano, M.A.2
Goryunov, D.3
-
133
-
-
35748965834
-
Small heat shock protein Hsp27 prevents heat-induced aggregation of F-actin by forming soluble complexes with denatured actin
-
Pivovarova A V, Chebotareva N A, Chernik I S et al (2007) Small heat shock protein Hsp27 prevents heat-induced aggregation of F-actin by forming soluble complexes with denatured actin. FEBS J 274:5937-5948
-
(2007)
FEBS J
, vol.274
, pp. 5937-5948
-
-
Pivovarova, A.V.1
Chebotareva, N.A.2
Chernik, I.S.3
-
134
-
-
38049170987
-
Unmasking different mechanical and energetic roles for the small heat shock proteins CryAB and HSPB2 using genetically modified mouse hearts
-
Pinz I, Robbins J, Rajasekaran N S et al (2008) Unmasking different mechanical and energetic roles for the small heat shock proteins CryAB and HSPB2 using genetically modified mouse hearts. FASEB J 22:84-92
-
(2008)
FASEB J
, vol.22
, pp. 84-92
-
-
Pinz, I.1
Robbins, J.2
Rajasekaran, N.S.3
-
135
-
-
0034842209
-
Familial myopathy with desmin storage seen as a granulo-filamentar, electron-dense material without mutation of the alphabeta-crystallin gene
-
Pou Serradell A, Lloreta Trull J, Corominas Torres J et al (2001) Familial myopathy with desmin storage seen as a granulo-filamentar, electron-dense material without mutation of the alphabeta-crystallin gene. Neurologia 16:195-203
-
(2001)
Neurologia
, vol.16
, pp. 195-203
-
-
Pou Serradell, A.1
Lloreta Trull, J.2
Corominas Torres, J.3
-
136
-
-
0031715855
-
Phosphorylation is not essential for protection of L929 cells by Hsp25 against H2O2-mediated disruption actin cytoskeleton, a protection which appears related to the redox change mediated by Hsp25
-
Preville X, Gaestel M and Arrigo A P (1998a) Phosphorylation is not essential for protection of L929 cells by Hsp25 against H2O2-mediated disruption actin cytoskeleton, a protection which appears related to the redox change mediated by Hsp25. Cell Stress Chaperones 3:177-187
-
(1998)
Cell Stress Chaperones
, vol.3
, pp. 177-187
-
-
Preville, X.1
Gaestel, M.2
Arrigo, A.P.3
-
137
-
-
0039171658
-
Analysis of the role of Hsp25 phosphorylation reveals the importance of the oligomerization state of this small heat shock protein in its protective function against TNFalpha- and hydrogen peroxide-induced cell death
-
Preville X, Schultz H, Knauf U et al (1998b) Analysis of the role of Hsp25 phosphorylation reveals the importance of the oligomerization state of this small heat shock protein in its protective function against TNFalpha- and hydrogen peroxide-induced cell death. J Cell Biochem 69:436-452
-
(1998)
J Cell Biochem
, vol.69
, pp. 436-452
-
-
Preville, X.1
Schultz, H.2
Knauf, U.3
-
138
-
-
42749092501
-
Expression of the small heat shock protein family in the mouse CNS: Differential anatomical and biochemical compartmentalization
-
Quraishe S, Asuni A, Boelens W C et al (2008) Expression of the small heat shock protein family in the mouse CNS: Differential anatomical and biochemical compartmentalization. Neuroscience 153:483-491
-
(2008)
Neuroscience
, vol.153
, pp. 483-491
-
-
Quraishe, S.1
Asuni, A.2
Boelens, W.C.3
-
139
-
-
34547681313
-
Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice
-
Rajasekaran N S, Connell P, Christians E S et al (2007) Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. Cell 130:427-39
-
(2007)
Cell
, vol.130
, pp. 427-439
-
-
Rajasekaran, N.S.1
Connell, P.2
Christians, E.S.3
-
140
-
-
29644445485
-
AlphaB-crystallin, a small heat-shock protein, prevents the amyloid fibril growth of an amyloid beta-peptide and beta2-microglobulin
-
Raman B, Ban T, Sakai M et al (2005) AlphaB-crystallin, a small heat-shock protein, prevents the amyloid fibril growth of an amyloid beta-peptide and beta2-microglobulin. Biochem J 392:573-581
-
(2005)
Biochem J
, vol.392
, pp. 573-581
-
-
Raman, B.1
Ban, T.2
Sakai, M.3
-
141
-
-
41849150778
-
Clinical variability of autosomal dominant cataract, microcornea and corneal opacity and novel mutation in the alpha A crystallin gene (CRYAA)
-
Richter L, Flodman P, Barria von-Bischhoffshausen F et al (2008) Clinical variability of autosomal dominant cataract, microcornea and corneal opacity and novel mutation in the alpha A crystallin gene (CRYAA). Am J Med Genet A 146:833-842
-
(2008)
Am J Med Genet A
, vol.146
, pp. 833-842
-
-
Richter, L.1
Flodman, P.2
Barria Von-Bischhoffshausen, F.3
-
142
-
-
34250561475
-
A new puffing pattern induced by a temperature shock and DNP in Drosophila
-
Ritossa F M (1962) A new puffing pattern induced by a temperature shock and DNP in Drosophila. Experientia 18:571-573
-
(1962)
Experientia
, vol.18
, pp. 571-573
-
-
Ritossa, F.M.1
-
143
-
-
27644596641
-
Opinion: What is the role of protein aggregation in neurodegeneration?
-
Ross C A and Poirier M A (2005) Opinion: What is the role of protein aggregation in neurodegeneration? Nat Rev Mol Cell Biol 6:891-898
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 891-898
-
-
Ross, C.A.1
Poirier, M.A.2
-
144
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
Rubinsztein D C (2006) The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 443:780-786
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
145
-
-
41149087881
-
Role of the IXI/V motif in oligomer assembly and function of StHsp14.0, a small heat shock protein from the acidothermophilic archaeon, Sulfolobus tokodaii strain 7
-
Saji H, Iizuka R, Yoshida T (2008) Role of the IXI/V motif in oligomer assembly and function of StHsp14.0, a small heat shock protein from the acidothermophilic archaeon, Sulfolobus tokodaii strain 7. Proteins 71:771-82
-
(2008)
Proteins
, vol.71
, pp. 771-782
-
-
Saji, H.1
Iizuka, R.2
Yoshida, T.3
-
146
-
-
3042711961
-
Desmin-related cardiomyopathy in transgenic mice: A cardiac amyloidosis
-
Sanbe A, Osinska H, Saffitz J E et al (2004) Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis. Proc Natl Acad Sci U S A 101:10132-6
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10132-10136
-
-
Sanbe, A.1
Osinska, H.2
Saffitz, J.E.3
-
147
-
-
26444486021
-
Reversal of amyloid-induced heart disease in desminrelated cardiomyopathy
-
Sanbe A, Osinska H, Villa C et al (2005) Reversal of amyloid-induced heart disease in desminrelated cardiomyopathy. Proc Natl Acad Sci U S A 102:13592-13597
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13592-13597
-
-
Sanbe, A.1
Osinska, H.2
Villa, C.3
-
148
-
-
19444376495
-
HSP27 protects AML cells against VP-16-induced apoptosis through modulation of p38 and c-Jun
-
Schepers H, Geugien M, van der Toorn M et al (2005) HSP27 protects AML cells against VP-16-induced apoptosis through modulation of p38 and c-Jun. Exp Hematol 33:660-670
-
(2005)
Exp Hematol
, vol.33
, pp. 660-670
-
-
Schepers, H.1
Geugien, M.2
Van Der Toorn, M.3
-
149
-
-
0344664368
-
Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations
-
Selcen D and Engel A G (2003) Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations. Ann Neurol 54:804-810
-
(2003)
Ann Neurol
, vol.54
, pp. 804-810
-
-
Selcen, D.1
Engel, A.G.2
-
150
-
-
40849140683
-
Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression
-
Sharp P S, Akbar M T, Bouri S et al (2008) Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression. Neurobiol Dis 30:42-55
-
(2008)
Neurobiol Dis
, vol.30
, pp. 42-55
-
-
Sharp, P.S.1
Akbar, M.T.2
Bouri, S.3
-
151
-
-
36348957457
-
Myopathy-associated alphaB-crystallin mutants: Abnormal phosphorylation, intracellular location, and interactions with other small heat shock proteins
-
Simon S, Fontaine J M, Martin J L et al (2007) Myopathy-associated alphaB-crystallin mutants: abnormal phosphorylation, intracellular location, and interactions with other small heat shock proteins. J Biol Chem 282:34276-34287
-
(2007)
J Biol Chem
, vol.282
, pp. 34276-34287
-
-
Simon, S.1
Fontaine, J.M.2
Martin, J.L.3
-
152
-
-
33846618592
-
Association of alphaB-crystallin, a small heat shock protein, with actin: Role in modulating actin filament dynamics in vivo
-
Singh B N, Rao K S, Ramakrishna T et al (2007) Association of alphaB-crystallin, a small heat shock protein, with actin: role in modulating actin filament dynamics in vivo. J Mol Biol 366:756-767
-
(2007)
J Mol Biol
, vol.366
, pp. 756-767
-
-
Singh, B.N.1
Rao, K.S.2
Ramakrishna, T.3
-
154
-
-
0033584258
-
The molecular chaperone alphaB-crystallin enhances amyloid beta neurotoxicity
-
Stege G J, Renkawek K, Overkamp P S et al (1999) The molecular chaperone alphaB-crystallin enhances amyloid beta neurotoxicity. Biochem Biophys Res Commun 262:152-156
-
(1999)
Biochem Biophys Res Commun
, vol.262
, pp. 152-156
-
-
Stege, G.J.1
Renkawek, K.2
Overkamp, P.S.3
-
155
-
-
0034019637
-
Mutation of a gene encoding a putative chaperonin causes McKusick-Kaufman syndrome
-
Stone D L, Slavotinek A, Bouffard G G et al (2000) Mutation of a gene encoding a putative chaperonin causes McKusick-Kaufman syndrome. Nat Genet 25:79-82
-
(2000)
Nat Genet
, vol.25
, pp. 79-82
-
-
Stone, D.L.1
Slavotinek, A.2
Bouffard, G.G.3
-
156
-
-
0036375506
-
A critical motif for oligomerization and chaperone activity of bacterial alpha-heat shock proteins
-
Studer S, Obrist M, Lentze N et al (2002) A critical motif for oligomerization and chaperone activity of bacterial alpha-heat shock proteins. Eur J Biochem 269:3578-3586
-
(2002)
Eur J Biochem
, vol.269
, pp. 3578-3586
-
-
Studer, S.1
Obrist, M.2
Lentze, N.3
-
157
-
-
1342334759
-
Interaction of human HSP22 (HSPB8) with other small heat shock proteins
-
Sun X, Fontaine J M, Rest J S et al (2004) Interaction of human HSP22 (HSPB8) with other small heat shock proteins. J Biol Chem 279:2394-402
-
(2004)
J Biol Chem
, vol.279
, pp. 2394-2402
-
-
Sun, X.1
Fontaine, J.M.2
Rest, J.S.3
-
158
-
-
19944433659
-
Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L
-
Tang B S, Zhao G H, Luo W et al (2005) Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L. Hum Genet 116:222-4
-
(2005)
Hum Genet
, vol.116
, pp. 222-224
-
-
Tang, B.S.1
Zhao, G.H.2
Luo, W.3
-
159
-
-
47749125013
-
Autophagy is an adaptive response in desminrelated cardiomyopathy
-
Tannous P, Zhu H, Johnstone J L et al (2008a) Autophagy is an adaptive response in desminrelated cardiomyopathy. Proc Natl Acad Sci U S A 105:9745-9750
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9745-9750
-
-
Tannous, P.1
Zhu, H.2
Johnstone, J.L.3
-
160
-
-
47749105267
-
Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy
-
Tannous P, Zhu H, Nemchenko A et al (2008b) Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy. Circulation 117:3070-3078
-
(2008)
Circulation
, vol.117
, pp. 3070-3078
-
-
Tannous, P.1
Zhu, H.2
Nemchenko, A.3
-
161
-
-
0016373748
-
Protein synthesis in salivary glands of Drosophila melanogaster. Relation to chromosomal puffs
-
Tissières A, Mitchell H K and Tracy U M (1974) Protein synthesis in salivary glands of Drosophila melanogaster. Relation to chromosomal puffs. J Mol Biol 84:389-398
-
(1974)
J Mol Biol
, vol.84
, pp. 389-398
-
-
Tissières, A.1
Mitchell, H.K.2
Tracy, U.M.3
-
162
-
-
42349107955
-
Site-directed mutations in the C-terminal extension of human alphaB-crystallin affect chaperone function and block amyloid fibril formation
-
Treweek T M, Ecroyd H, Williams D M et al (2007) Site-directed mutations in the C-terminal extension of human alphaB-crystallin affect chaperone function and block amyloid fibril formation. PLoS ONE 2:e1046
-
(2007)
PLoS ONE
, vol.2
, pp. e1046
-
-
Treweek, T.M.1
Ecroyd, H.2
Williams, D.M.3
-
163
-
-
13444260973
-
R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable
-
Treweek T M, Rekas A, Lindner R A et al (2005) R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable. FEBS J 272:711-724
-
(2005)
FEBS J
, vol.272
, pp. 711-724
-
-
Treweek, T.M.1
Rekas, A.2
Lindner, R.A.3
-
164
-
-
0037899026
-
Pathogenesis of axonal dystrophy and demyelination in alphaA-crystallin-expressing transgenic mice
-
Van Rijk A F, Sweers M A, Merkx G F et al (2003) Pathogenesis of axonal dystrophy and demyelination in alphaA-crystallin-expressing transgenic mice. Int J Exp Pathol 84:91-9
-
(2003)
Int J Exp Pathol
, vol.84
, pp. 91-99
-
-
Van Rijk, A.F.1
Sweers, M.A.2
Merkx, G.F.3
-
166
-
-
17344361902
-
A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy
-
Vicart P, Caron A, Guicheney P et al (1998) A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy. Nat Genet 20:92-95
-
(1998)
Nat Genet
, vol.20
, pp. 92-95
-
-
Vicart, P.1
Caron, A.2
Guicheney, P.3
-
168
-
-
0029658123
-
Alpha-crystallin stabilizes actin filaments and prevents cytochalasin-induced depolymerization in a phosphorylation-dependent manner
-
Wang K, Spector A (1996) alpha-crystallin stabilizes actin filaments and prevents cytochalasin-induced depolymerization in a phosphorylation-dependent manner. Eur J Biochem 242:56-66
-
(1996)
Eur J Biochem
, vol.242
, pp. 56-66
-
-
Wang, K.1
Spector, A.2
-
169
-
-
0242637569
-
AlphaB-crystallin modulates protein aggregation of abnormal desmin
-
Wang X, Klevitsky R, Huang W et al (2003) AlphaB-crystallin modulates protein aggregation of abnormal desmin. Circ Res 93:998-1005
-
(2003)
Circ Res
, vol.93
, pp. 998-1005
-
-
Wang, X.1
Klevitsky, R.2
Huang, W.3
-
170
-
-
0035816115
-
Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice
-
Wang X, Osinska H, Klevitsky R et al (2001) Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice. Circ Res 89:84-91
-
(2001)
Circ Res
, vol.89
, pp. 84-91
-
-
Wang, X.1
Osinska, H.2
Klevitsky, R.3
-
171
-
-
33646857038
-
Small heat shock proteins inhibit amyloid-beta protein aggregation and cerebrovascular amyloid-beta protein toxicity
-
Wilhelmus M M, Boelens W C, Otte-Höller I et al (2006a) Small heat shock proteins inhibit amyloid-beta protein aggregation and cerebrovascular amyloid-beta protein toxicity. Brain Res 1089:67-78
-
(2006)
Brain Res
, vol.1089
, pp. 67-78
-
-
Wilhelmus, M.M.1
Boelens, W.C.2
Otte-Höller, I.3
-
172
-
-
33644960735
-
Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains
-
Wilhelmus M M, Otte-Höller I, Wesseling P et al (2006b) Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains. Neuropathol Appl Neurobiol 32:119-130
-
(2006)
Neuropathol Appl Neurobiol
, vol.32
, pp. 119-130
-
-
Wilhelmus, M.M.1
Otte-Höller, I.2
Wesseling, P.3
-
174
-
-
0036566675
-
Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin
-
Wyttenbach A, Sauvageot O, Carmichael J et al (2002) Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin. Hum Mol Genet 11:1137-1151
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1137-1151
-
-
Wyttenbach, A.1
Sauvageot, O.2
Carmichael, J.3
-
175
-
-
41949133095
-
Mechanism of small heat shock protein function in vivo: A knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death
-
Xi J H, Bai F, Gross J et al (2008) Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death. J Biol Chem 283:5801-14
-
(2008)
J Biol Chem
, vol.283
, pp. 5801-5814
-
-
Xi, J.H.1
Bai, F.2
Gross, J.3
-
176
-
-
36248947271
-
Disruption of neurofilament network with aggregation of light neurofilament protein: A common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1
-
Zhai J, Lin H, Julien J P et al (2007) Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1. Hum Mol Genet 16:3103-16
-
(2007)
Hum Mol Genet
, vol.16
, pp. 3103-3116
-
-
Zhai, J.1
Lin, H.2
Julien, J.P.3
-
177
-
-
34447331291
-
Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: Chronic neurodegeneration does not induce Hsp27 activation
-
Zourlidou A, Gidalevitz T, Kristiansen M et al (2007) Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation. Hum Mol Genet 16:1078-1090
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1078-1090
-
-
Zourlidou, A.1
Gidalevitz, T.2
Kristiansen, M.3
-
178
-
-
33645276591
-
Mechanisms of disease: A molecular genetic update on hereditary axonal neuropathies
-
Zuchner S and Vance J M (2006) Mechanisms of disease: a molecular genetic update on hereditary axonal neuropathies. Nat Clin Pract Neurol 2:45-53
-
(2006)
Nat Clin Pract Neurol
, vol.2
, pp. 45-53
-
-
Zuchner, S.1
Vance, J.M.2
|