Unmasking different mechanical and energetic roles for the small heat shock proteins CryAB and HSPB2 using genetically modified mouse hearts

FASEB Journal

Volumn 22, Issue 1, 2008, Pages 84-92

  Pinz, Ilka ^a,d   Robbins, Jeffrey ^b   Rajasekaran, Namakkal S ^c   Benjamin, Ivor J ^c   Ingwall, Joanne S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^d Maine Medical Center Research Institute   (United States)

Author keywords

Cardiac function; Transgenesis

Indexed keywords

SMALL HEAT SHOCK PROTEIN; SMALL HEAT SHOCK PROTEIN B2; SMALL HEAT SHOCK PROTEIN CRYAB; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; ALPHA CRYSTALLIN; CRYAB PROTEIN, MOUSE; DOBUTAMINE; HEAT SHOCK PROTEIN; HSPB2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ENERGY CONSUMPTION; HEART MUSCLE ISCHEMIA; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; REPERFUSION INJURY; TRANSGENIC MOUSE; ANIMAL; ENERGY METABOLISM; GENETIC ENGINEERING; HEART CONTRACTION; HEART MUSCLE; HYDROLYSIS; METABOLISM; NUCLEAR MAGNETIC RESONANCE; PHYSIOLOGY; WESTERN BLOTTING;

MUS;

ADENOSINE TRIPHOSPHATE; ALPHA-CRYSTALLIN B CHAIN; ANIMALS; BLOTTING, WESTERN; DOBUTAMINE; ENERGY METABOLISM; GENETIC ENGINEERING; HEAT-SHOCK PROTEINS; HYDROLYSIS; MICE; MYOCARDIAL CONTRACTION; MYOCARDIUM; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; REPERFUSION INJURY;

EID: 38049170987     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-8130com     Document Type: Article

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