Expression of R120G-αB-crystallin causes aberrant desmin and αB-crystallin aggregation and cardiomyopathy in mice

Circulation Research

Volumn 89, Issue 1, 2001, Pages 84-91

  Wang, Xuejun ^a   Osinska, Hanna ^a   Klevitsky, Raisa ^a   Gerdes, A Martin ^a   Nieman, Michelle ^a   Lorenz, John ^a   Hewett, Timothy ^a   Robbins, Jeffrey ^a  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

Author keywords

Cardiac; Genetics; Heart disease; Mouse; Transgenic

Indexed keywords

ALPHA CRYSTALLIN; DESMIN; CRYSTALLIN; MESSENGER RNA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CARDIOMYOPATHY; CONTROLLED STUDY; GENE MUTATION; GENE OVEREXPRESSION; HEART MUSCLE CELL; MISSENSE MUTATION; MOUSE; MUSCLE FIBRIL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; TRANSGENIC MOUSE; ANIMAL; BIOSYNTHESIS; CARDIOMEGALY; GENETICS; HEART CONTRACTION; HEART MUSCLE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SURVIVAL RATE; ULTRASTRUCTURE;

ANIMALS; CARDIOMEGALY; CRYSTALLINS; DESMIN; MICE; MICE, TRANSGENIC; MUTATION, MISSENSE; MYOCARDIAL CONTRACTION; MYOCARDIUM; RNA, MESSENGER; SURVIVAL RATE;

EID: 0035816115     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh1301.092688     Document Type: Article

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