Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells

Molecular Brain Research

Volumn 134, Issue 2, 2005, Pages 256-274

  Patel, Yogesh J K ^a   Payne Smith, Martin D ^a   De Belleroche, Jacqueline ^b   Latchman, David S ^a,c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b CHARING CROSS HOSPITAL   (United Kingdom)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Amyotrophic lateral sclerosis; Cell survival apoptosis; Copper zinc superoxide dismutase (SOD1); Heat shock protein (Hsp); HSV viral gene delivery; Neuroprotection; SOD1 mutations G93A and G93R

Indexed keywords

CASPASE INHIBITOR; COPPER ZINC SUPEROXIDE DISMUTASE; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; ATROPHY; BRAIN CORTEX; BRAIN NERVE CELL; BRAIN STEM; CONTROLLED STUDY; DEATH; DEGENERATIVE DISEASE; DIAPHRAGM PARALYSIS; ENZYME ACTIVITY; FAMILIAL DISEASE; MAMMAL CELL; MOTOR NEURON DISEASE; MOUSE; MUSCLE WEAKNESS; NERVE CELL NECROSIS; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD;

MAMMALIA;

EID: 17044403380     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2004.10.028     Document Type: Article

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