메뉴 건너뛰기




Volumn 132, Issue 1, 2012, Pages 2-6

Pharmacology and potential physiological significance of schistosome multidrug resistance transporters

Author keywords

ABC transporters; Drug resistance; Multidrug resistance; P glycoprotein; Schistosoma

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; ABC TRANSPORTER G1; BREAST CANCER RESISTANCE PROTEIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PRAZIQUANTEL; RNA;

EID: 80052459275     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2011.03.004     Document Type: Review
Times cited : (33)

References (57)
  • 2
    • 0022332711 scopus 로고
    • Praziquantel: mechanisms of anti-schistosomal activity
    • Andrews P. Praziquantel: mechanisms of anti-schistosomal activity. Pharmac. Ther. 1985, 29:129-156.
    • (1985) Pharmac. Ther. , vol.29 , pp. 129-156
    • Andrews, P.1
  • 4
    • 22844449116 scopus 로고    scopus 로고
    • Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein
    • Ardelli B.F., Guerriero S.B., Prichard R.K. Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein. Mol. Biochem. Parasitol. 2005, 143:58-66.
    • (2005) Mol. Biochem. Parasitol. , vol.143 , pp. 58-66
    • Ardelli, B.F.1    Guerriero, S.B.2    Prichard, R.K.3
  • 5
    • 33644868408 scopus 로고    scopus 로고
    • Ivermectin imposes selection pressure on P-glycoprotein from Onchocerca volvulus: linkage disequilibrium and genotype diversity
    • Ardelli B.F., Guerriero S.B., Prichard R.K. Ivermectin imposes selection pressure on P-glycoprotein from Onchocerca volvulus: linkage disequilibrium and genotype diversity. Parasitology 2006, 132:375-386.
    • (2006) Parasitology , vol.132 , pp. 375-386
    • Ardelli, B.F.1    Guerriero, S.B.2    Prichard, R.K.3
  • 6
    • 70349574862 scopus 로고    scopus 로고
    • P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus
    • Bartley D.J., McAllister H., Bartley Y., Dupuy J., Menez C., Alvinerie M., Jackson F., Lespine A. P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus. Parasitology 2009, 136:1081-1088.
    • (2009) Parasitology , vol.136 , pp. 1081-1088
    • Bartley, D.J.1    McAllister, H.2    Bartley, Y.3    Dupuy, J.4    Menez, C.5    Alvinerie, M.6    Jackson, F.7    Lespine, A.8
  • 8
    • 0032531334 scopus 로고    scopus 로고
    • Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus
    • Blackhall W.J., Liu H.Y., Xu M., Prichard R.K., Beech R.N. Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus. Mol. Biochem. Parasitol. 1998, 95:193-201.
    • (1998) Mol. Biochem. Parasitol. , vol.95 , pp. 193-201
    • Blackhall, W.J.1    Liu, H.Y.2    Xu, M.3    Prichard, R.K.4    Beech, R.N.5
  • 9
    • 38749105426 scopus 로고    scopus 로고
    • P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles
    • Blackhall W.J., Prichard R.K., Beech R.N. P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles. Vet. Parasitol. 2008, 152:101-107.
    • (2008) Vet. Parasitol. , vol.152 , pp. 101-107
    • Blackhall, W.J.1    Prichard, R.K.2    Beech, R.N.3
  • 10
    • 0028244986 scopus 로고
    • Two Schistosoma mansoni cDNAs encoding ATP-binding cassette (ABC) family proteins
    • Bosch I.B., Wang Z.X., Tao L.F., Shoemaker C.B. Two Schistosoma mansoni cDNAs encoding ATP-binding cassette (ABC) family proteins. Mol. Biochem. Parasitol. 1994, 65:351-356.
    • (1994) Mol. Biochem. Parasitol. , vol.65 , pp. 351-356
    • Bosch, I.B.1    Wang, Z.X.2    Tao, L.F.3    Shoemaker, C.B.4
  • 11
    • 34548126499 scopus 로고    scopus 로고
    • Chemotherapy of schistosomiasis: present and future
    • Caffrey C.R. Chemotherapy of schistosomiasis: present and future. Curr. Opin. Chem. Biol. 2007, 11:433-439.
    • (2007) Curr. Opin. Chem. Biol. , vol.11 , pp. 433-439
    • Caffrey, C.R.1
  • 12
    • 73949155491 scopus 로고    scopus 로고
    • Overcoming multidrug resistance in cancer: clinical studies of P-glycoprotein inhibitors
    • Coley H.M. Overcoming multidrug resistance in cancer: clinical studies of P-glycoprotein inhibitors. Methods Mol. Biol. 2010, 596:341-358.
    • (2010) Methods Mol. Biol. , vol.596 , pp. 341-358
    • Coley, H.M.1
  • 13
    • 78650511348 scopus 로고    scopus 로고
    • Use of fluorescent probes as a useful tool to identify resistant Schistosoma mansoni isolates to praziquantel
    • Couto F.F., Coelho P.M., Araujo N., Kusel J.R., Katz N., Mattos A.C. Use of fluorescent probes as a useful tool to identify resistant Schistosoma mansoni isolates to praziquantel. Parasitology 2010, 137:1791-1797.
    • (2010) Parasitology , vol.137 , pp. 1791-1797
    • Couto, F.F.1    Coelho, P.M.2    Araujo, N.3    Kusel, J.R.4    Katz, N.5    Mattos, A.C.6
  • 15
    • 0034917716 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • Dean M., Rzhetsky A., Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res. 2001, 11:1156-1166.
    • (2001) Genome Res. , vol.11 , pp. 1156-1166
    • Dean, M.1    Rzhetsky, A.2    Allikmets, R.3
  • 16
    • 57049129327 scopus 로고    scopus 로고
    • Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis
    • Doenhoff M.J., Cioli D., Utzinger J. Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis. Curr. Opin. Infecti. Dis. 2008, 21:659-667.
    • (2008) Curr. Opin. Infecti. Dis. , vol.21 , pp. 659-667
    • Doenhoff, M.J.1    Cioli, D.2    Utzinger, J.3
  • 18
    • 33646165902 scopus 로고    scopus 로고
    • Praziquantel for the treatment of schistosomiasis: its use for control in areas with endemic disease and prospects for drug resistance
    • Doenhoff M.J., Pica-Mattoccia L. Praziquantel for the treatment of schistosomiasis: its use for control in areas with endemic disease and prospects for drug resistance. Expert. Rev. Anti. Infect. Ther. 2006, 4:199-210.
    • (2006) Expert. Rev. Anti. Infect. Ther. , vol.4 , pp. 199-210
    • Doenhoff, M.J.1    Pica-Mattoccia, L.2
  • 19
    • 0142227135 scopus 로고    scopus 로고
    • Drugs for the control of parasitic diseases: current status and development in schistosomiasis
    • Fenwick A., Savioli L., Engels D., Robert Bergquist N., Todd M.H. Drugs for the control of parasitic diseases: current status and development in schistosomiasis. Trends Parasitol. 2003, 19:509-515.
    • (2003) Trends Parasitol. , vol.19 , pp. 509-515
    • Fenwick, A.1    Savioli, L.2    Engels, D.3    Robert Bergquist, N.4    Todd, M.H.5
  • 22
    • 21644469993 scopus 로고    scopus 로고
    • 2+ channels targets of praziquantel action?
    • 2+ channels targets of praziquantel action?. Int. J. Parasitol. 2005, 35:1-9.
    • (2005) Int. J. Parasitol. , vol.35 , pp. 1-9
    • Greenberg, R.M.1
  • 24
    • 33748062666 scopus 로고    scopus 로고
    • The potential inhibitory effect of antiparasitic drugs and natural products on P-glycoprotein mediated efflux
    • Hayeshi R., Masimirembwa C., Mukanganyama S., Ungell A.L. The potential inhibitory effect of antiparasitic drugs and natural products on P-glycoprotein mediated efflux. Eur. J. Pharm. Sci. 2006, 29:70-81.
    • (2006) Eur. J. Pharm. Sci. , vol.29 , pp. 70-81
    • Hayeshi, R.1    Masimirembwa, C.2    Mukanganyama, S.3    Ungell, A.L.4
  • 25
    • 70449504005 scopus 로고    scopus 로고
    • Schistosomiasis in Africa: an emerging tragedy in our new global health decade
    • Hotez P.J., Fenwick A. Schistosomiasis in Africa: an emerging tragedy in our new global health decade. PLoS Neglect. Trop. D 2009, 3:e485.
    • (2009) PLoS Neglect. Trop. D , vol.3
    • Hotez, P.J.1    Fenwick, A.2
  • 26
    • 67649550594 scopus 로고    scopus 로고
    • Drug resistance mechanisms in helminths: is it survival of the fittest?
    • James C.E., Hudson A.L., Davey M.W. Drug resistance mechanisms in helminths: is it survival of the fittest?. Trends Parasitol. 2009, 25:328-335.
    • (2009) Trends Parasitol. , vol.25 , pp. 328-335
    • James, C.E.1    Hudson, A.L.2    Davey, M.W.3
  • 27
    • 70449123539 scopus 로고    scopus 로고
    • An update on P-glycoprotein and drug resistance in Schistosoma mansoni
    • James C.E., Hudson A.L., Davey M.W. An update on P-glycoprotein and drug resistance in Schistosoma mansoni. Trends Parasitol. 2009, 25:538-539.
    • (2009) Trends Parasitol. , vol.25 , pp. 538-539
    • James, C.E.1    Hudson, A.L.2    Davey, M.W.3
  • 28
    • 0033958086 scopus 로고    scopus 로고
    • Multiple physiological functions for multidrug transporter P-glycoprotein?
    • Johnstone R.W., Ruefli A.A., Smyth M.J. Multiple physiological functions for multidrug transporter P-glycoprotein?. Trends Biochem. Sci. 2000, 25:1-6.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 1-6
    • Johnstone, R.W.1    Ruefli, A.A.2    Smyth, M.J.3
  • 30
    • 17144426125 scopus 로고    scopus 로고
    • Multidrug resistance in parasites: ABC transporters, P-glycoproteins and molecular modelling
    • Jones P.M., George A.M. Multidrug resistance in parasites: ABC transporters, P-glycoproteins and molecular modelling. Int. J. Parasitol. 2005, 35:555-566.
    • (2005) Int. J. Parasitol. , vol.35 , pp. 555-566
    • Jones, P.M.1    George, A.M.2
  • 31
    • 75149198677 scopus 로고    scopus 로고
    • Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel
    • Kasinathan R.S., Goronga T., Messerli S.M., Webb T.R., Greenberg R.M. Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel. FASEB J. 2010, 24:128-135.
    • (2010) FASEB J. , vol.24 , pp. 128-135
    • Kasinathan, R.S.1    Goronga, T.2    Messerli, S.M.3    Webb, T.R.4    Greenberg, R.M.5
  • 32
    • 77953808820 scopus 로고    scopus 로고
    • Schistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantel
    • Kasinathan R.S., Morgan W.M., Greenberg R.M. Schistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantel. Mol. Biochem. Parasitol. 2010, 173:25-31.
    • (2010) Mol. Biochem. Parasitol. , vol.173 , pp. 25-31
    • Kasinathan, R.S.1    Morgan, W.M.2    Greenberg, R.M.3
  • 33
    • 0041331790 scopus 로고    scopus 로고
    • P-glycoprotein in helminths: function and perspectives for anthelmintic treatment and reversal of resistance
    • Kerboeuf D., Blackhall W., Kaminsky R., von Samson-Himmelstjerna G. P-glycoprotein in helminths: function and perspectives for anthelmintic treatment and reversal of resistance. Int. J. Antimicrob. Ag. 2003, 22:332-346.
    • (2003) Int. J. Antimicrob. Ag. , vol.22 , pp. 332-346
    • Kerboeuf, D.1    Blackhall, W.2    Kaminsky, R.3    von Samson-Himmelstjerna, G.4
  • 34
    • 84880079245 scopus 로고    scopus 로고
    • Schistosomiasis: challenges and opportunities
    • Institute of Medicine, Board on Global Health, Forum on Microbial Threats. Institute of Medicine.
    • King, C.H., 2010. Schistosomiasis: challenges and opportunities, Institute of Medicine, Board on Global Health, Forum on Microbial Threats. Institute of Medicine. http://iom.edu.
    • (2010)
    • King, C.H.1
  • 35
    • 53149090539 scopus 로고    scopus 로고
    • Expression of ATP-binding cassette multidrug transporters in the giant liver fluke Fasciola gigantica and their possible involvement in the transport of bile salts and anthelmintics
    • Kumkate S., Chunchob S., Janvilisri T. Expression of ATP-binding cassette multidrug transporters in the giant liver fluke Fasciola gigantica and their possible involvement in the transport of bile salts and anthelmintics. Mol. Cell. Biochem. 2008, 317:77-84.
    • (2008) Mol. Cell. Biochem. , vol.317 , pp. 77-84
    • Kumkate, S.1    Chunchob, S.2    Janvilisri, T.3
  • 37
    • 0141888537 scopus 로고    scopus 로고
    • The role of ABC transporters in clinical practice
    • Leonard G.D., Fojo T., Bates S.E. The role of ABC transporters in clinical practice. The Oncologist 2003, 8:411-424.
    • (2003) The Oncologist , vol.8 , pp. 411-424
    • Leonard, G.D.1    Fojo, T.2    Bates, S.E.3
  • 38
    • 45449101104 scopus 로고    scopus 로고
    • ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics
    • Lespine A., Alvinerie M., Vercruysse J., Prichard R.K., Geldhof P. ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics. Trends Parasitol. 2008, 24:293-298.
    • (2008) Trends Parasitol. , vol.24 , pp. 293-298
    • Lespine, A.1    Alvinerie, M.2    Vercruysse, J.3    Prichard, R.K.4    Geldhof, P.5
  • 39
    • 33747202180 scopus 로고    scopus 로고
    • Multidrug transporters as drug targets
    • Liang X.J., Aszalos A. Multidrug transporters as drug targets. Curr. Drug Targets 2006, 7:911-921.
    • (2006) Curr. Drug Targets , vol.7 , pp. 911-921
    • Liang, X.J.1    Aszalos, A.2
  • 41
    • 67650373884 scopus 로고    scopus 로고
    • Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility
    • Messerli S.M., Kasinathan R.S., Morgan W., Spranger S., Greenberg R.M. Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility. Mol. Biochem. Parasitol. 2009, 167:54-59.
    • (2009) Mol. Biochem. Parasitol. , vol.167 , pp. 54-59
    • Messerli, S.M.1    Kasinathan, R.S.2    Morgan, W.3    Spranger, S.4    Greenberg, R.M.5
  • 43
    • 33644850898 scopus 로고    scopus 로고
    • Responses of the surface membrane and excretory system of Schistosoma mansoni to damage and to treatment with praziquantel and other biomolecules
    • Oliveira F.A., Kusel J.R., Ribeiro F., Coelho P.M. Responses of the surface membrane and excretory system of Schistosoma mansoni to damage and to treatment with praziquantel and other biomolecules. Parasitology 2006, 132:321-330.
    • (2006) Parasitology , vol.132 , pp. 321-330
    • Oliveira, F.A.1    Kusel, J.R.2    Ribeiro, F.3    Coelho, P.M.4
  • 44
    • 1542358686 scopus 로고    scopus 로고
    • Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment
    • Pica-Mattoccia L., Cioli D. Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment. Int. J. Parasitol. 2004, 34:527-533.
    • (2004) Int. J. Parasitol. , vol.34 , pp. 527-533
    • Pica-Mattoccia, L.1    Cioli, D.2
  • 46
    • 0022454720 scopus 로고
    • Schistosoma mansoni: chemotherapy of infections of different ages
    • Sabah A.A., Fletcher C., Webbe G., Doenhoff M.J. Schistosoma mansoni: chemotherapy of infections of different ages. Exp. Parasitol. 1986, 61:294-303.
    • (1986) Exp. Parasitol. , vol.61 , pp. 294-303
    • Sabah, A.A.1    Fletcher, C.2    Webbe, G.3    Doenhoff, M.J.4
  • 47
    • 0032789210 scopus 로고    scopus 로고
    • Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins
    • Sangster N.C., Bannan S.C., Weiss A.S., Nulf S.C., Klein R.D., Geary T.G. Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins. Exp. Parasitol. 1999, 91:250-257.
    • (1999) Exp. Parasitol. , vol.91 , pp. 250-257
    • Sangster, N.C.1    Bannan, S.C.2    Weiss, A.S.3    Nulf, S.C.4    Klein, R.D.5    Geary, T.G.6
  • 48
    • 0036971105 scopus 로고    scopus 로고
    • Functional visualization of the excretory system of adult Schistosoma mansoni by the fluorescent marker resorufin
    • Sato H., Kusel J.R., Thornhill J. Functional visualization of the excretory system of adult Schistosoma mansoni by the fluorescent marker resorufin. Parasitology 2002, 125:527-535.
    • (2002) Parasitology , vol.125 , pp. 527-535
    • Sato, H.1    Kusel, J.R.2    Thornhill, J.3
  • 49
    • 0842265672 scopus 로고    scopus 로고
    • Excretion of fluorescent substrates of mammalian multidrug resistance-associated protein (MRP) in the Schistosoma mansoni excretory system
    • Sato H., Kusel J.R., Thornhill J. Excretion of fluorescent substrates of mammalian multidrug resistance-associated protein (MRP) in the Schistosoma mansoni excretory system. Parasitology 2004, 128:43-52.
    • (2004) Parasitology , vol.128 , pp. 43-52
    • Sato, H.1    Kusel, J.R.2    Thornhill, J.3
  • 50
    • 39749084704 scopus 로고    scopus 로고
    • Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges
    • Shukla S., Wu C.P., Ambudkar S.V. Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges. Expert. Opin. Drug Metab. Toxicol. 2008, 4:205-223.
    • (2008) Expert. Opin. Drug Metab. Toxicol. , vol.4 , pp. 205-223
    • Shukla, S.1    Wu, C.P.2    Ambudkar, S.V.3
  • 55
    • 0021858516 scopus 로고
    • Effects of praziquantel on different developmental stages of Schistosoma mansoni in vitro and in vivo
    • Xiao S.H., Catto B.A., Webster L.T. Effects of praziquantel on different developmental stages of Schistosoma mansoni in vitro and in vivo. J. Infect. Dis. 1985, 151:1130-1137.
    • (1985) J. Infect. Dis. , vol.151 , pp. 1130-1137
    • Xiao, S.H.1    Catto, B.A.2    Webster, L.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.