Drug resistance in schistosomes

Parasitic Flatworms: Molecular Biology, Biochemistry, Immunology and Physiology

Volumn , Issue , 2006, Pages 256-268

  Day, T A ^a   Botros, S ^b  

^a IOWA STATE UNIVERSITY   (United States)

^b THEODOR BILHARZ RESEARCH INSTITUTE   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33646765724     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (67)

1. Anderson, T.J., Blouin, M.S. and Beech, R.N. (1998) Population biology of parasitic nematodes: applications of genetic markers. Advances in Parasitology 41, 219-283.
2. Andrews, P. (1985) Praziquantel: mechanisms of anti-schistosomal activity. Pharmacology and Therapeutics 29, 129-156.
3. Andrews, P., Thomas, H., Pohlke, R. and Seubert, J. (1983) Praziquantel. Medicinal Research Reviews 3, 147-200.
4. Barakat, R., Farghaly, A., El Masry, A.G., El-Sayed, M.K. and Hussein, M.H. (2000) The epidemiology of schistosomiasis in Egypt: patterns of Schistosoma mansoni infection and morbidity in Kafer El-Sheikh. American Journal of Tropical Medicine and Hygiene 62, 21-27.
5. Behbehani, M. and Savioli, L. (1998) Report of the WHO informal consultation on monitoring of drug efficacy in the control of schistosomiasis and intestinal nematodes. World Health Organization, Geneva.
6. Bonesso-Sabadini, P.I.P. and Dias, L.C. (2002) Altered response of strain of Schistosoma mansoni to oxamniquine and praziquantel. Memorias do Instituto Oswaldo Cruz 97, 381-385.
7. Botros, S., Sayed, H., Amer, N., El-Ghannam, M., Bennett, J.L. and Day, T.A. (2005) Current status of sensitivity to praziquantel in a focus of potential drug resistance in Egypt. International Journal for Parasitology 35, 787-791.
8. Bricker, C.S., Depenbusch, J.W., Bennett, J.L. and Thompson, D.P. (1983) The relationship between tegumental disruption and muscle contraction in Schistosoma mansoni exposed to various compounds. Zeitschrift für Parasitenkund 69, 61-71.
9. Brindley, P.J. and Sher, A. (1987) The chemotherapeutic effect of praziquantel against Schistosoma mansoni is dependent on host antibody response. Journal of Immunology 139, 215-220.
10. Brindley, P.J., Strand, M., Norden, A.P. and Sher, A. (1989) Role of host antibody in the chemotherapeutic action of praziquantel against Schistosoma mansoni: identification of target antigens. Molecular and Biochemical Parasitology 34, 99-108.
11. Bruce, J.I., Dias, L.C., Liang, Y.S. and Coles, G.C. (1987) Drug resistance in schistosomiasis: a review. Memorias do Instituto Oswaldo Cruz 82(Suppl. 4), 143-150.
12. Campos, R., Moreira, A.A., Sette, H., Chamone, D.A. and Da Silva, L.C. (1976) Hycanthone resistance in a human strain of Schistosoma mansoni. Transactions of the Royal Society of Tropical Medicine and Hygiene 70, 261-262.
13. Chitsulo, L., Engels, D., Montresor, A. and Savioli, L. (2000) The global status of schistosomiasis and its control. Acta Tropica 77, 41-51.
14. Chitsulo, L., Loverde, P. and Engels, D. (2004) Schistosomiasis. Nature Reviews Microbiology 2, 12-13.
15. Cioli, D. and Pica Mattoccia, L. (1984) Genetic analysis of hycanthone resistance in Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 33, 80-88.
16. Cioli, D., Pica-Mattoccia, L., Rosenberg, S. and Archer, S. (1985) Evidence for the mode of antischistosomal action of hycanthone. Life Sciences 37, 161-167.
17. Cioli, D., Pica-Mattoccia, L. and Moroni, R. (1992) Schistosoma mansoni: hycanthone/oxamniquine resistance is controlled by a single autosomal recessive gene. Experimental Parasitology 75, 425-432.
18. Cioli, D., Pica-Mattoccia, L. and Archer, S. (1993) Drug resistance in schistosomes. Parasitology Today 9, 162-166.
19. Cioli, D., Pica-Mattoccia, L. and Archer, S. (1995) Antischistosomal drugs: past, present. and future? Pharmacology and Therapeutics 68, 35-85.
20. Cline, B.L., Richards, F.O., El Alamy, M.A., El Hak, S., Ruiz-Tiben, E., Hughes, J.M. and McNeeley, D.F. (1989) 1983 Nile Delta schistosomiasis survey: 48 years after Scott. American Journal of Tropical Medicine and Hygiene 41, 56-62.
21. Coles, G.C. and Kinoti, G. (1997) Defining resistance in schistosoma. Parasitology Today 13, 157-158.
22. Coles, G.C., Mutahi, W.T., Kinoti, G.K., Bruce, J.I. and Katz, N. (1987) Tolerance of Kenyan Schistosoma mansoni to oxamniquine. Transactions of the Royal Society of Tropical Medicine and Hygiene 81, 782-785.
23. Conder, G.A. and Campbell, W.C. (1995) Chemotherapy of nematode infections of veterinary importance, with special reference to drug resistance. Advances in Parasitology 35, 1-84.
24. Danso-Appiah, A. and De Vlas, S.J. (2002) Interpreting low praziquantel cure rates of Schistosoma mansoni infections in Senegal. Trends in Parasitology 18, 125-129.
25. Day, T.A., Bennett, J.L. and Pax, R.A. (1992) Praziquantel: the enigmatic antiparasitic. Parasitology Today 8, 342-344.
26. De Clercq, D., Vercruysse, J., Picquet, M., Shaw, D.J., Diop, M., Ly, A. and Gryseels, B. (1999) The epidemiology of a recent focus of mixed Schistosoma haematobium and Schistosoma mansoni infections around the 'Lac de Guiers' in the Senegal River Basin, Senegal. Tropical Medicine and International Health 4, 544-550.
27. Degu, G., Mengistu, G. and Jones, J. (2002) Praziquantel efficacy against schistosomiasis mansoni in schoolchildren in north-west Ethiopia. Transactions of the Royal Society of Tropical Medicine and Hygiene 96, 444-445.
28. Dias, L.C., Pedro, R.J., Rigo, E., Goto, M.M. and Mafra, G.L. (1978) A human strain of Schistosoma mansoni resistant to schistosomicides. Revista de Saude Publica 12, 110.
29. Dias, L.C., Pedro, R.J. and Debelardini, E.R. (1982) Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/or hycanthone: resistance of Schistosoma mansoni to schistosomicidal agents. Transactions of the Royal Society of Tropical Medicine and Hygiene 76, 652-659.
30. Drescher, K.M., Rogers, E.J., Bruce, J.I., Katz, N., Dias, L.C. and Coles, G.C. (1993) Response of drug resistant isolates of Schistosoma mansoni to antischistosomal agents. Memorias do Instituto Oswaldo Cruz 88, 89-95.
31. El-Khoby, T., Galal, N. and Fenwick, A. (1998) The USAID/Government of Egypt's Schistosomiasis Research Project (SRP). Parasitology Today 14, 92-96.
32. El-Khoby, T., Galal, N., Fenwick, A., Barakat, R., El-Hawey, A., Nooman, Z., Habib, M., Abdel-Wahab, F., Gabr, N.S., Hammam, H.M., Hussein, M.H., Mikhail, N.N., Cline, B.L. and Strickland, G.T. (2000) The epidemiology of schistosomiasis in Egypt: summary findings in nine governorates. American Journal of Tropical Medicine and Hygiene 62, 88-99.
33. Ernould, J.C., Ba, K. and Sellin, B. (1999) Increase of intestinal schistosomiasis after praziquantel treatment in a Schistosoma haematobium and Schistosoma mansoni mixed focus. Acta Tropica 73, 143-152.
34. Fallon, P.G. and Doenhoff, M.J. (1994) Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific. American Journal of Tropical Medicine and Hygiene 51, 83-88.
35. Fallon, P.G., Sturrock, R.F., Niang, A.C. and Doenhoff, M.J. (1995) Short report: diminished susceptibility to praziquantel in a Senegal isolate of Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 53, 61-62.
36. Fallon, P.G., Mubarak, J.S., Fookes, R.E., Niang, M., Butterworth, A.E., Sturrock, R.F. and Doenhoff, M.J. (1997) Schistosoma mansoni: maturation rate and drug susceptibility of different geographic isolates. Experimental Parasitology 86, 29-36.
37. Fenwick, A., Savioli, L., Engels, D., Bergquist, R.N. and Todd, M.H. (2003) Drugs for the control of parasitic diseases: current status and development in schistosomiasis. Trends in Parasitology 19, 509-515.
38. Geerts, S. and Gryseels, B. (2000) Drug resistance in human helminths: current situation and lessons from livestock. Clinical Microbiology Reviews 13, 207-222.
39. Gonnert, R. and Andrews, P. (1977) Praziquantel, a new board-spectrum antischistosomal agent. Zeitschrift für Parasitenkund 52, 129-150.
40. Gryseels, B., Nkulikyinka, L. and Coosemans, M.H. (1987) Field trials of praziquantel and oxamniquine for the treatment of schistosomiasis mansoni in Burundi. Transactions of the Royal Society of Tropical Medicine and Hygiene 81, 641-644.
41. Gryseels, B., Stelma, F.F., Talla, I., van Dam, G.J., Polman, K., Sow, S., Diaw, M., Sturrock, R.F., Doehring-Schwerdtfeger, E. and Kardorff, R. (1994) Epidemiology, immunology and chemotherapy of Schistosoma mansoni infections in a recently exposed community in Senegal. Tropical and Geograpical Medicine 46, 209-219.
42. Gryseels, B., Mbaye, A., De Vlas, S.J., Stelma, F.F., Guisse, F., Van Lieshout, L., Faye, D., Diop, M., Ly, A., Tchuem-Tchuente, L.A., Engels, D. and Polman, K. (2001) Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence. Tropical Medicine and International Health 6, 864-873.
43. Guimaraes, R.X., Tchakerian, A., Dias, L.C., de Almeida, F.M., Vilela, M.P., Cabeca, M. and Takeda, A.K. (1979) Resistance to hycanthone and oxamniquine in patients with a clinical hepato-intestinal form of schistosomiasis. AMB; Revista da Associaco Medica Brasileira 25, 48-50.
44. Ismail, M., Metwally, A., Farghaly, A., Bruce, J., Tao, L.F. and Bennett, J.L. (1996) Characterization of isolates of Schistosoma mansoni from Egyptian villagers that tolerate high doses of praziquantel. American Journal of Tropical Medicine and Hygiene 55, 214-218.
45. Ismail, M., Botros, S., Metwally, A., William, S., Farghally, A., Tao, L.F., Day, T.A. and Bennett, J.L. (1999) Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers. American Journal of Tropical Medicine and Hygiene 60, 932-935.
46. Katz, N. (1975) Clinical evaluation of niridazole and hycanthone in schistosomiasis mansoni endemic areas. Journal of Toxicology and Environmental Health 1, 203-209.
47. Katz, N., Zicker, F. and Pereira, J.P. (1977) Field trials with oxamniquine in a schistosomiasis mansoniendemic area. American Journal of Tropical Medicine and Hygiene 26, 234-237.
48. Katz, N., Rocha, R.S. and Chaves, A. (1979) Preliminary trials with praziquantel in human infections due to Schistosoma mansoni. Bulletin of the World Health Organisation 57, 781-785.
49. Kenworthy, J.D., Ye, P., Wu, G.C., Yu, H., Shi, Y.J., Li, H. and Coles, G.C. (2003) Field evaluation of a test for praziquantel resistance in Schistosoma sp. Veterinary Parasitology 113, 83-87.
50. Kinoti, G. (1987) The significance of variation in susceptibility of Schistosoma mansoni to the antischistosomal drug oxamniquine. Memorias do Instituto Oswaldo Cruz 82, 151-156.
51. Liang, Y.S., Coles, G.C., Doenhoff, M.J. and Southgate, V.R. (2001) In vitro responses of praziquantel-resistant and -susceptible Schistosoma mansoni to praziquantel. International Journal for Parasitology 31, 1227-1235.
52. Pax, R., Bennett, J.L. and Fetterer, R. (1978) A benzodiazepine derivative and praziquantel: effects on musculature of Schistosoma mansoni and Schistosoma japonicum. Naunyn Schmiedebergs Archives of Pharmacology 304, 309-315.
53. Pica-Mattoccia, L., Archer, S. and Cioli, D. (1992) Hycanthone resistance in schistosomes correlates with the lack of an enzymatic activity which produces the covalent binding of hycanthone to parasite macromolecules. Molecular and Biochemical Parasitology 55, 167-175.
54. Pica-Mattoccia, L., Novi, A. and Cioli, D. (1997) Enzymatic basis for the lack of oxamniquine activity in Schistosoma haematobium infections. Parasitology Research 83, 687-689.
55. Picquet, M., Vercruysse, J., Shaw, D.J., Diop, M. and Ly, A. (1998) Efficacy of praziquantel against Schistosoma mansoni in northern Senegal. Transactions of the Royal Society of Tropical Medicine and Hygiene 92, 90-93.
56. Prichard, R.K., Hall, C.A., Kelly, J.D., Martin, I.C. and Donald, A.D. (1980) The problem of anthelmintic resistance in nematodes. Australian Veterinary Journal 56, 239-251.
57. Rogers, S.H. and Bueding, E. (1971) Hycanthone resistance: development in Schistosoma mansoni. Science 172, 1057-1058.
58. Sabah, A.A., Fletcher, C., Webbe, G. and Doenhoff, M.J. (1985) Schistosoma mansoni: reduced efficacy of chemotherapy in infected T-cell-deprived mice. Experimental Parasitology 60, 348-354.
59. Santos, A.T., Blas, B.L., Nosenas, J.S., Portillo, G.P., Ortega, O.M., Hayashi, M. and Boehme, K. (1979) Preliminary clinical trials with praziquantel in Schistosoma japonicum infections in the Philippines. Bulletin of the World Health Organisation 57, 793-799.
60. Scott, J. (1937) The incidence and distribution of human schistosomiasis in Egypt. American Journal of Hygiene 25, 566-614.
61. Stelma, F.F., Talla, I., Polman, K., Niang, M., Sturrock, R.F., Deelder, A.M. and Gryseels, B. (1993) Epidemiology of Schistosoma mansoni infection in a recently exposed community in northern Senegal. American Journal of Tropical Medicine and Hygiene 49, 701-706.
62. Stelma, F.F., Talla, I., Sow, S., Kongs, A., Niang, M., Polman, K., Deelder, A.M. and Gryseels, B. (1995) Efficacy and side effects of praziquantel in an epidemic focus of Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 53, 167-170.
63. Stelma, F.F., Sall, S., Daff, B., Sow, S., Niang, M. and Gryseels, B. (1997) Oxamniquine cures Schistosoma mansoni infection in a focus in which cure rates with praziquantel are unusually low. Journal of Infectious Disease 176, 304-307.
64. van Lieshout, L., Stelma, F.F., Guisse, F., Falcao Ferreira, S.T., Polman, K., van Dam, G.J., Diakhate, M., Sow, S., Deelder, A. and Gryseels, B. (1999) The contribution of host-related factors to low cure rates of praziquantel for the treatment of Schistosoma mansoni in Senegal. American Journal of Tropical Medicine and Hygiene 61, 760-765.
65. WHO (2000) Report of the WHO informal consultation on schistosomiasis in low transmission areas: control strategies and criteria for elimination. World Health Organization, London.
66. William, S., Botros, S., Ismail, M., Farghally, A., Day, T.A. and Bennett, J.L. (2001a) Praziquantel-induced tegumental damage in vitro is diminished in schistosomes derived from praziquantel-resistant infections. Parasitology 122, 63-66.
67. William, S., Sabra, A., Ramzy, F., Mousa, M., Demerdash, Z., Bennett, J.L., Day, T.A. and Botros, S. (2001b) Stability and reproductive fitness of Schistosoma mansoni isolates with decreased sensitivity to praziquantel. International Journal for Parasitology 31, 1093-1000.