-
1
-
-
78649486408
-
Cardiovascular outcomes in Type 2 diabetes: The impact of preventative therapies
-
Zoungas S, Patel A. Cardiovascular outcomes in Type 2 diabetes: the impact of preventative therapies. Ann. NY Acad. Sci. 1212, 29-40 (2010).
-
(2010)
Ann. NY Acad. Sci.
, vol.1212
, pp. 29-40
-
-
Zoungas, S.1
Patel, A.2
-
2
-
-
34548414111
-
The pathophysiology of cardiovascular disease in diabetes mellitus and the future of therapy
-
Thomas JE, Foody JM. The pathophysiology of cardiovascular disease in diabetes mellitus and the future of therapy. J. Cardiometab. Syndr. 2(2), 108-113 (2007).
-
(2007)
J. Cardiometab. Syndr.
, vol.2
, Issue.2
, pp. 108-113
-
-
Thomas, J.E.1
Foody, J.M.2
-
3
-
-
77950796225
-
Type 2 diabetes: Postprandial hyperglycemia and increased cardiovascular risk
-
Aryangat AV, Gerich JE. Type 2 diabetes: postprandial hyperglycemia and increased cardiovascular risk. Vasc. Health Risk Manag. 6, 145-155 (2010).
-
(2010)
Vasc. Health Risk Manag.
, vol.6
, pp. 145-155
-
-
Aryangat, A.V.1
Gerich, J.E.2
-
4
-
-
77949553029
-
Pre-diabetes and the risk for cardiovascular disease: A systematic review of the evidence
-
Ford ES, Zhao G, Li C. Pre-diabetes and the risk for cardiovascular disease: a systematic review of the evidence. J. Am. Coll. Cardiol. 55(13), 1310-1317 (2010).
-
(2010)
J. Am. Coll. Cardiol.
, vol.55
, Issue.13
, pp. 1310-1317
-
-
Ford, E.S.1
Zhao, G.2
Li, C.3
-
6
-
-
77956069166
-
Hypoglycemia, diabetes and cardiovascular events
-
Desouza CV, Bolli GB, Fonseca V. Hypoglycemia, diabetes and cardiovascular events. Diabetes Care 33(6), 1389-1394 (2010).
-
(2010)
Diabetes Care
, vol.33
, Issue.6
, pp. 1389-1394
-
-
Desouza, C.V.1
Bolli, G.B.2
Fonseca, V.3
-
7
-
-
77449094773
-
The economic consequences of diabetes and cardiovascular disease in the United States
-
Ariza MA, Vimalananda VG, Rosenzweig JL. The economic consequences of diabetes and cardiovascular disease in the United States. Rev. Endocr. Metab. Disord. 11(1), 1-10 (2010).
-
(2010)
Rev. Endocr. Metab. Disord.
, vol.11
, Issue.1
, pp. 1-10
-
-
Ma, A.1
Vimalananda, V.G.2
Rosenzweig, J.L.3
-
9
-
-
78650141628
-
Intensive glucose lowering and cardiovascular disease prevention in diabetes: Reconciling the recent clinical trial data
-
Mazzone T.
-
Mazzone T. Intensive glucose lowering and cardiovascular disease prevention in diabetes: reconciling the recent clinical trial data. Circulation 122(21), 2201-2211 (2010).
-
(2010)
Circulation
, vol.122
, Issue.21
, pp. 2201-2211
-
-
-
10
-
-
79551482877
-
Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial - Clinical implications
-
Ismail-Beigi F. Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial - clinical implications. Clin. Chem. 57(2), 261-263 (2011).
-
(2011)
Clin. Chem.
, vol.57
, Issue.2
, pp. 261-263
-
-
Ismail-Beigi, F.1
-
11
-
-
57649111589
-
Mixed dyslipidemia, metabolic syndrome, diabetes mellitus, and cardiovascular disease: Clinical implications
-
Cannon CP. Mixed dyslipidemia, metabolic syndrome, diabetes mellitus, and cardiovascular disease: clinical implications. Am. J. Cardiol. 102(12A), 5L-9L (2008).
-
(2008)
Am. J. Cardiol.
, vol.102
, Issue.12 A
-
-
Cannon, C.P.1
-
12
-
-
77953272214
-
Lipid disorders in Type 2 diabetes
-
Laakso M. Lipid disorders in Type 2 diabetes. Endocrinol. Nutr. 56(Suppl. 4), 43-45 (2009).
-
(2009)
Endocrinol. Nutr.
, vol.56
, Issue.SUPPL. 4
, pp. 43-45
-
-
Laakso, M.1
-
13
-
-
33748450504
-
Diabetes and dyslipidaemia
-
DOI 10.1111/j.1463-1326.2005.00516.x
-
Schwartz SL. Diabetes and dyslipidaemia. Diabetes Obes. Metab. 8(4), 355-364 (2006). (Pubitemid 44349227)
-
(2006)
Diabetes, Obesity and Metabolism
, vol.8
, Issue.4
, pp. 355-364
-
-
Schwartz, S.L.1
-
14
-
-
42449114912
-
Targeting cardiovascular risk in patients with diabetes: Management of dyslipidemia
-
DOI 10.1097/MED.0b013e3282f5ff98, PII 0126602920080400000007
-
Ali YS, Linton MF, Fazio S. Targeting cardiovascular risk in patients with diabetes: management of dyslipidemia. Curr. Opin. Endocrinol. Diabetes Obes. 15(2), 142-146 (2008). (Pubitemid 351651727)
-
(2008)
Current Opinion in Endocrinology, Diabetes and Obesity
, vol.15
, Issue.2
, pp. 142-146
-
-
Ali, Y.S.1
Linton, M.F.2
Fazio, S.3
-
15
-
-
77953397149
-
Management of dyslipidemia in people with Type 2 diabetes mellitus
-
Dunn FL. Management of dyslipidemia in people with Type 2 diabetes mellitus. Rev. Endocr. Metab. Disord. 11(1), 41-51 (2010).
-
(2010)
Rev. Endocr. Metab. Disord.
, vol.11
, Issue.1
, pp. 41-51
-
-
Dunn, F.L.1
-
16
-
-
77955920038
-
Fish oils for cardiovascular disease: Impact on diabetes
-
Rudkowska I. Fish oils for cardiovascular disease: impact on diabetes. Maturitas 67(1), 25-28 (2010).
-
(2010)
Maturitas
, vol.67
, Issue.1
, pp. 25-28
-
-
Rudkowska, I.1
-
17
-
-
40349093031
-
Combination therapy in the management of mixed dyslipidaemia
-
DOI 10.1111/j.1365-2796.2008.01933.x
-
Cannon CP. Combination therapy in the management of mixed dyslipidaemia. J. Intern. Med. 263(4), 353-365 (2008). (Pubitemid 351342686)
-
(2008)
Journal of Internal Medicine
, vol.263
, Issue.4
, pp. 353-365
-
-
Cannon, C.P.1
-
19
-
-
77949874469
-
Obesity, inflammation, and cardiovascular risk
-
Mathieu P, Lemieux I, Despres JP. Obesity, inflammation, and cardiovascular risk. Clin. Pharmacol. Ther. 87(4), 407-416 (2010).
-
(2010)
Clin. Pharmacol. Ther.
, vol.87
, Issue.4
, pp. 407-416
-
-
Mathieu, P.1
Lemieux, I.2
Despres, J.P.3
-
20
-
-
40149109169
-
Visceral obesity and the heart
-
Mathieu P, Pibarot P, Larose E, Poirier P, Marette A, Despres JP. Visceral obesity and the heart. Int. J. Biochem. Cell. Biol. 40(5), 821-836 (2008).
-
(2008)
Int. J. Biochem. Cell. Biol.
, vol.40
, Issue.5
, pp. 821-836
-
-
Mathieu, P.1
Pibarot, P.2
Larose, E.3
Poirier, P.4
Marette, A.5
Despres, J.P.6
-
21
-
-
19944431203
-
Pericardial and visceral adipose tissues measured volumetrically with computed tomography are highly associated in type 2 diabetic families
-
DOI 10.1097/00004424-200502000-00007
-
Wheeler GL, Shi R, Beck SR et al. Pericardial and visceral adipose tissues measured volumetrically with computed tomography are highly associated in Type 2 diabetic families. Invest. Radiol. 40(2), 97-101 (2005). (Pubitemid 40144415)
-
(2005)
Investigative Radiology
, vol.40
, Issue.2
, pp. 97-101
-
-
Wheeler, G.L.1
Shi, R.2
Beck, S.R.3
Langefeld, C.D.4
Lenchik, L.5
Wagenknecht, L.E.6
Freedman, B.I.7
Rich, S.S.8
Bowden, D.W.9
Chen, M.Y.10
Carr, J.J.11
-
22
-
-
0344442670
-
Echocardiographic Epicardial Adipose Tissue Is Related to Anthropometric and Clinical Parameters of Metabolic Syndrome: A New Indicator of Cardiovascular Risk
-
DOI 10.1210/jc.2003-030698
-
Iacobellis G, Ribaudo MC, Assael F et al. Echocardiographic epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk. J. Clin. Endocrinol. Metab. 88(11), 5163-5168 (2003). (Pubitemid 37452712)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.11
, pp. 5163-5168
-
-
Iacobellis, G.1
Ribaudo, M.C.2
Assael, F.3
Vecci, E.4
Tiberti, C.5
Zappaterreno, A.6
Di Mario, U.7
Leonetti, F.8
-
23
-
-
0344393607
-
Human Epicardial Adipose Tissue Is a Source of Inflammatory Mediators
-
DOI 10.1161/01.CIR.0000099542.57313.C5
-
Mazurek T, Zhang L, Zalewski A et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 108(20), 2460-2466 (2003). (Pubitemid 37444406)
-
(2003)
Circulation
, vol.108
, Issue.20
, pp. 2460-2466
-
-
Mazurek, T.1
Zhang, L.2
Zalewski, A.3
Mannion, J.D.4
Diehl, J.T.5
Arafat, H.6
Sarov-Blat, L.7
O'Brien, S.8
Keiper, E.A.9
Johnson, A.G.10
Martin, J.11
Goldstein, B.J.12
Shi, Y.13
-
24
-
-
34249686103
-
Recipes for creating animal models of diabetic cardiovascular disease
-
DOI 10.1161/01.RES.0000266449.37396.1f, PII 0000301220070525000008
-
Hsueh W, Abel ED, Breslow JL et al. Recipes for creating animal models of diabetic cardiovascular disease. Circ. Res. 100(10), 1415-1427 (2007). (Pubitemid 46834754)
-
(2007)
Circulation Research
, vol.100
, Issue.10
, pp. 1415-1427
-
-
Hsueh, W.1
Abel, E.D.2
Breslow, J.L.3
Maeda, N.4
Davis, R.C.5
Fisher, E.A.6
Dansky, H.7
McClain, D.A.8
McIndoe, R.9
Wassef, M.K.10
Rabadan-Diehl, C.11
Goldberg, I.J.12
-
25
-
-
4944224324
-
Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions
-
DOI 10.1172/JCI200417867
-
Renard CB, Kramer F, Johansson F et al. Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions. J. Clin. Invest. 114(5), 659-668 (2004). (Pubitemid 39578756)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.5
, pp. 659-668
-
-
Renard, C.B.1
Kramer, F.2
Johansson, F.3
Lamharzi, N.4
Tannock, L.R.5
Von Herrath, M.G.6
Chait, A.7
Bornfeldt, K.E.8
-
26
-
-
85047690129
-
Why does diabetes increase atherosclerosis? I don't know!
-
DOI 10.1172/JCI200422826
-
Goldberg IJ. Why does diabetes increase atherosclerosis? I don't know! J. Clin. Invest. 114(5), 613-615 (2004). (Pubitemid 39578749)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.5
, pp. 613-615
-
-
Goldberg, I.J.1
-
27
-
-
26944446556
-
Models of type 2 diabetes
-
DOI 10.1016/j.ddmod.2005.08.011, PII S1740675705000472
-
Somwar R, Fang X, Sweeney G. Models of Type 2 diabetes. Drug Discovery Today 2(3), 183-189 (2005). (Pubitemid 41472365)
-
(2005)
Drug Discovery Today: Disease Models
, vol.2
, Issue.3
, pp. 183-189
-
-
Somwar, R.1
Fang, X.2
Sweeney, G.3
-
28
-
-
0035287440
-
Mouse models of hyperlipidemia and atherosclerosis
-
Fazio S, Linton MF. Mouse models of hyperlipidemia and atherosclerosis. Front. Biosci. 6, D515-D525 (2001).
-
(2001)
Front. Biosci.
, vol.6
-
-
Fazio, S.1
Linton, M.F.2
-
29
-
-
0035723938
-
-/- mice
-
Veniant MM, Withycombe S, Young SG. Lipoprotein size and atherosclerosis susceptibility in ApoE(-/-) and Ldlr(-/-) mice. Arterioscler. Thromb. Vasc. Biol. 21(10), 1567-1570 (2001). (Pubitemid 34215573)
-
(2001)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.21
, Issue.10
, pp. 1567-1570
-
-
Veniant, M.M.1
Withycombe, S.2
Young, S.G.3
-
30
-
-
0032532670
-
Lipoprotein clearance mechanisms in LDL receptor-deficient 'apo-B48- only' and 'apo-B100-only' mice
-
Veniant MM, Zlot CH, Walzem RL et al. Lipoprotein clearance mechanisms in LDL receptor-deficient Apo-B48-only' and Apo-B100-only' mice. J. Clin. Invest. 102(8), 1559-1568 (1998). (Pubitemid 28492223)
-
(1998)
Journal of Clinical Investigation
, vol.102
, Issue.8
, pp. 1559-1568
-
-
Veniant, M.M.1
Zlot, C.H.2
Walzem, R.L.3
Pierotti, V.4
Driscoll, R.5
Dichek, D.6
Herz, J.7
Young, S.G.8
-
31
-
-
24644458573
-
Gene transfers of vascular endothelial growth factor-A, vascular endothelial growth factor-B, vascular endothelial growth factor-C, and vascular endothelial growth factor-D have no effects on atherosclerosis in hypercholesterolemic low-density lipoprotein-receptor/apolipoprotein B48-deficient mice
-
DOI 10.1161/CIRCULATIONAHA.105.534107
-
Leppanen P, Koota S, Kholova I et al. Gene transfers of vascular endothelial growth factor-A, vascular endothelial growth factor-B, vascular endothelial growth factor-C, and vascular endothelial growth factor-D have no effects on atherosclerosis in hypercholesterolemic low-density lipoprotein-receptor/ apolipoprotein B48-deficient mice. Circulation 112(9), 1347-1352 (2005). (Pubitemid 41266731)
-
(2005)
Circulation
, vol.112
, Issue.9
, pp. 1347-1352
-
-
Leppanen, P.1
Koota, S.2
Kholova, I.3
Koponen, J.4
Fieber, C.5
Eriksson, U.6
Alitalo, K.7
Yla-Herttuala, S.8
-
32
-
-
0036793431
-
Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice
-
DOI 10.1194/jlr.M200108-JLR200
-
Fazio S, Babaev VR, Burleigh ME, Major AS, Hasty AH, Linton MF. Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice. J. Lipid Res. 43(10), 1602-1609 (2002). (Pubitemid 35168274)
-
(2002)
Journal of Lipid Research
, vol.43
, Issue.10
, pp. 1602-1609
-
-
Fazio, S.1
Babaev, V.R.2
Burleigh, M.E.3
Major, A.S.4
Hasty, A.H.5
Linton, M.F.6
-
33
-
-
24644510706
-
Double face of VEGF
-
DOI 10.1161/CIRCULATIONAHA.105.566166
-
Tsutsumi Y, Losordo DW. Double face of VEGF. Circulation 112(9), 1248-1250 (2005). (Pubitemid 41266718)
-
(2005)
Circulation
, vol.112
, Issue.9
, pp. 1248-1250
-
-
Tsutsumi, Y.1
Losordo, D.W.2
-
35
-
-
0037222386
-
Dietary Cod protein restores insulin-induced activation of phosphatidylinositol 3-kinase/Akt and GLUT4 translocation to the T-tubules in skeletal muscle of high-fat-fed obese rats
-
DOI 10.2337/diabetes.52.1.29
-
Tremblay F, Lavigne C, Jacques H, Marette A. Dietary cod protein restores insulin-induced activation of phosphatidylinositol 3-kinase/Akt and GLUT4 translocation to the T-tubules in skeletal muscle of high-fat-fed obese rats. Diabetes 52(1), 29-37 (2003). (Pubitemid 36042104)
-
(2003)
Diabetes
, vol.52
, Issue.1
, pp. 29-37
-
-
Tremblay, F.1
Lavigne, C.2
Jacques, H.3
Marette, A.4
-
36
-
-
14244256097
-
Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: Possible involvement in obesity-linked insulin resistance
-
DOI 10.1210/en.2004-0921
-
Khamzina L, Veilleux A, Bergeron S, Marette A. Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance. Endocrinology 146(3), 1473-1481 (2005). (Pubitemid 40289337)
-
(2005)
Endocrinology
, vol.146
, Issue.3
, pp. 1473-1481
-
-
Khamzina, L.1
Veilleux, A.2
Bergeron, S.3
Marette, A.4
-
37
-
-
33645221822
-
Overexpression of Rad in muscle worsens diet-induced insulin resistance and glucose intolerance and lowers plasma triglyceride level
-
Ilany J, Bilan PJ, Kapur S et al. Overexpression of Rad in muscle worsens diet-induced insulin resistance and glucose intolerance and lowers plasma triglyceride level. Proc. Natl Acad. Sci. USA 103(12), 4481-4486 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.12
, pp. 4481-4486
-
-
Ilany, J.1
Bilan, P.J.2
Kapur, S.3
-
38
-
-
0034770292
-
Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle
-
DOI 10.1038/nm1001-1138
-
Perreault M, Marette A. Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle. Nat. Med. 7(10), 1138-1143 (2001). (Pubitemid 33010023)
-
(2001)
Nature Medicine
, vol.7
, Issue.10
, pp. 1138-1143
-
-
Perreault, M.1
Marette, A.2
-
39
-
-
0035093258
-
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice
-
Collins AR, Meehan WP, Kintscher U et al. Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 21(3), 365-371 (2001). (Pubitemid 32199117)
-
(2001)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.21
, Issue.3
, pp. 365-371
-
-
Collins, A.R.1
Meehan, W.P.2
Kintscher, U.3
Jackson, S.4
Wakino, S.5
Noh, G.6
Palinski, W.7
Hsueh, W.A.8
Law, R.E.9
-
40
-
-
0032515059
-
Diet-induced diabetes activates an osteogenic gene regulatory program in the aortas of low density lipoprotein receptor-deficient mice
-
DOI 10.1074/jbc.273.46.30427
-
Towler DA, Bidder M, Latifi T, Coleman T, Semenkovich CF. Diet-induced diabetes activates an osteogenic gene regulatory program in the aortas of low density lipoprotein receptor-deficient mice. J. Biol. Chem. 273(46), 30427-30434 (1998). (Pubitemid 28545516)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.46
, pp. 30427-30434
-
-
Towler, D.A.1
Bidder, M.2
Latifi, T.3
Coleman, T.4
Semenkovich, C.F.5
-
41
-
-
36048975971
-
Increased atherosclerotic lesion calcification in a novel mouse model combining insulin resistance, hyperglycemia, and hypercholesterolemia
-
DOI 10.1161/CIRCRESAHA.107.154401
-
Heinonen SE, Leppanen P, Kholova I et al. Increased atherosclerotic lesion calcification in a novel mouse model combining insulin resistance, hyperglycemia, and hypercholesterolemia. Circ. Res. 101(10), 1058-1067 (2007). (Pubitemid 350084983)
-
(2007)
Circulation Research
, vol.101
, Issue.10
, pp. 1058-1067
-
-
Heinonen, S.E.1
Leppanen, P.2
Kholova, I.3
Lumivuori, H.4
Hakkinen, S.-K.5
Bosch, F.6
Laakso, M.7
Yla-Herttuala, S.8
-
42
-
-
0034063375
-
Transgenic mice overexpressing insulin-like growth factor-II in β cells develop type 2 diabetes
-
Devedjian JC, George M, Casellas A et al. Transgenic mice overexpressing insulin-like growth factor-II in b cells develop Type 2 diabetes. J. Clin. Invest. 105(6), 731-740 (2000). (Pubitemid 30164111)
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.6
, pp. 731-740
-
-
Devedjian, J.-C.1
George, M.2
Casellas, A.3
Pujol, A.4
Visa, J.5
Pelegrin, M.6
Gros, L.7
Bosch, F.8
-
43
-
-
78651350647
-
PCSK9: An emerging target for treatment of hypercholesterolemia
-
Duff CJ, Hooper NM. PCSK9: an emerging target for treatment of hypercholesterolemia. Expert Opin. Ther. Targets 15(2), 157-168 (2011).
-
(2011)
Expert Opin. Ther. Targets
, vol.15
, Issue.2
, pp. 157-168
-
-
Duff, C.J.1
Hooper, N.M.2
-
44
-
-
9644266673
-
Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver
-
DOI 10.1074/jbc.M410077200
-
Park SW, Moon YA, Horton JD. Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver. J. Biol. Chem. 279(48), 50630-50638 (2004). (Pubitemid 39577880)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.48
, pp. 50630-50638
-
-
Sahng, W.P.1
Moon, Y.-A.2
Horton, J.D.3
-
45
-
-
77951224306
-
A proprotein convertase subtilisin-like/ kexin type 9 (PCSK9) C-terminal domain antibody antigen-binding fragment inhibits PCSK9 internalization and restores low density lipoprotein uptake
-
Ni YG, Condra JH, Orsatti L et al. A proprotein convertase subtilisin-like/ kexin type 9 (PCSK9) C-terminal domain antibody antigen-binding fragment inhibits PCSK9 internalization and restores low density lipoprotein uptake. J. Biol. Chem. 285(17), 12882-12891 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, Issue.17
, pp. 12882-12891
-
-
Ni, Y.G.1
Condra, J.H.2
Orsatti, L.3
-
46
-
-
77956262162
-
The influence of PCSK9 polymorphisms on serum low-density lipoprotein cholesterol and risk of atherosclerosis
-
Davignon J, Dubuc G, Seidah NG. The influence of PCSK9 polymorphisms on serum low-density lipoprotein cholesterol and risk of atherosclerosis. Curr. Atheroscler. Rep. 12(5), 308-315 (2010).
-
(2010)
Curr. Atheroscler. Rep.
, vol.12
, Issue.5
, pp. 308-315
-
-
Davignon, J.1
Dubuc, G.2
Seidah, N.G.3
-
47
-
-
77953535433
-
PCSK9 as a therapeutic target in atherosclerosis
-
Marian AJ. PCSK9 as a therapeutic target in atherosclerosis. Curr. Atheroscler. Rep. 12(3), 151-154 (2010).
-
(2010)
Curr. Atheroscler. Rep.
, vol.12
, Issue.3
, pp. 151-154
-
-
Marian, A.J.1
-
48
-
-
67649834056
-
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates
-
Chan JC, Piper DE, Cao Q et al. A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc. Natl Acad. Sci. USA 106(24), 9820-9825 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.24
, pp. 9820-9825
-
-
Chan, J.C.1
De, P.2
Cao, Q.3
-
49
-
-
78650904300
-
A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol
-
Ni YG, Di Marco S, Condra JH et al. A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo. J. Lipid Res. 52(1), 78-86 (2011).
-
(2011)
Vivo. J. Lipid Res.
, vol.52
, Issue.1
, pp. 78-86
-
-
Ni, Y.G.1
Di Marco, S.2
Condra, J.H.3
-
50
-
-
77956230636
-
Plasma PCSK9 is increased by fenofibrate and atorvastatin in a non-additive fashion in diabetic patients
-
Costet P, Hoffmann MM, Cariou B, Guyomarc'h Delasalle B, Konrad T, Winkler K. Plasma PCSK9 is increased by fenofibrate and atorvastatin in a non-additive fashion in diabetic patients. Atherosclerosis 212(1), 246-251 (2010).
-
(2010)
Atherosclerosis
, vol.212
, Issue.1
, pp. 246-251
-
-
Costet, P.1
Hoffmann, M.M.2
Cariou, B.3
Guyomarc'h Delasalle, B.4
Konrad, T.5
Winkler, K.6
-
51
-
-
79953317222
-
Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9
-
Ason B, Tep S, Davis HR Jr. et al. Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9. J. Lipid Res. 52(4), 679-687 (2011).
-
(2011)
J. Lipid Res.
, vol.52
, Issue.4
, pp. 679-687
-
-
Ason, B.1
Tep, S.2
Davis Jr., H.R.3
-
52
-
-
67749115977
-
Update on statin-mediated anti-inflammatory activities in atherosclerosis
-
Montecucco F, Mach F. Update on statin-mediated anti-inflammatory activities in atherosclerosis. Semin. Immunopathol. 31(1), 127-142 (2009).
-
(2009)
Semin. Immunopathol.
, vol.31
, Issue.1
, pp. 127-142
-
-
Montecucco, F.1
MacH, F.2
-
53
-
-
79952259618
-
Adipokines as novel biomarkers and regulators of the metabolic syndrome
-
Deng Y, Scherer PE. Adipokines as novel biomarkers and regulators of the metabolic syndrome. Ann. NY Acad. Sci. 1212, E1-E19 (2010).
-
(2010)
Ann. NY Acad. Sci.
, vol.1212
-
-
Deng, Y.1
Scherer, P.E.2
-
54
-
-
79959239180
-
Cardiovascular benefits of bariatric surgery in morbidly obese patients
-
Athyros VG, Tziomalos K, Karagiannis A, Mikhailidis DP. Cardiovascular benefits of bariatric surgery in morbidly obese patients. Obes. Rev 12(7), 515-524 (2011).
-
(2011)
Obes. Rev
, vol.12
, Issue.7
, pp. 515-524
-
-
Athyros, V.G.1
Tziomalos, K.2
Karagiannis, A.3
Mikhailidis, D.P.4
-
55
-
-
78349237728
-
Vascular actions of adipokines molecular mechanisms and therapeutic implications
-
Xu A, Wang Y, Lam KS, Vanhoutte PM. Vascular actions of adipokines molecular mechanisms and therapeutic implications. Adv. Pharmacol. 60, 229-255 (2010).
-
(2010)
Adv. Pharmacol.
, vol.60
, pp. 229-255
-
-
Xu, A.1
Wang, Y.2
Lam, K.S.3
Vanhoutte, P.M.4
-
56
-
-
58149499174
-
Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases
-
Yamauchi T, Kadowaki T. Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases. Int. J. Obes. 32(Suppl. 7), S13-S18 (2008).
-
(2008)
Int. J. Obes.
, vol.32
, Issue.SUPPL. 7
-
-
Yamauchi, T.1
Kadowaki, T.2
-
57
-
-
79955385479
-
Adiponectin provides cardiovascular protection in metabolic syndrome
-
Okamoto Y. Adiponectin provides cardiovascular protection in metabolic syndrome. Cardiol. Res. Pract. 2011, 313179 (2011).
-
(2011)
Cardiol. Res. Pract.
, vol.2011
, pp. 313179
-
-
Okamoto, Y.1
-
59
-
-
27144457438
-
Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms
-
DOI 10.1038/nm1295, PII N1295
-
Shibata R, Sato K, Pimentel DR et al. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat. Med. 11(10), 1096-1103 (2005). (Pubitemid 41486832)
-
(2005)
Nature Medicine
, vol.11
, Issue.10
, pp. 1096-1103
-
-
Shibata, R.1
Sato, K.2
Pimentel, D.R.3
Takemura, Y.4
Kihara, S.5
Ohashi, K.6
Funahashi, T.7
Ouchi, N.8
Walsh, K.9
-
60
-
-
34249670301
-
Adiponectin protects against the development of systolic dysfunction following myocardial infarction
-
DOI 10.1016/j.yjmcc.2007.03.808, PII S0022282807008772
-
Shibata R, Izumiya Y, Sato K et al. Adiponectin protects against the development of systolic dysfunction following myocardial infarction. J. Mol. Cell. Cardiol. 42(6), 1065-1074 (2007). (Pubitemid 46829193)
-
(2007)
Journal of Molecular and Cellular Cardiology
, vol.42
, Issue.6
, pp. 1065-1074
-
-
Shibata, R.1
Izumiya, Y.2
Sato, K.3
Papanicolaou, K.4
Kihara, S.5
Colucci, W.S.6
Sam, F.7
Ouchi, N.8
Walsh, K.9
-
61
-
-
78651260799
-
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
-
Holland WL, Miller RA, Wang ZV et al. Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. Nat. Med. 17(1), 55-63 (2011).
-
(2011)
Nat. Med.
, vol.17
, Issue.1
, pp. 55-63
-
-
Holland, W.L.1
Miller, R.A.2
Wang, Z.V.3
-
62
-
-
79954493068
-
Intracoronary adiponectin at reperfusion reduces infarct size in a porcine myocardial infarction model
-
Debinski M, Buszman PP, Milewski K et al. Intracoronary adiponectin at reperfusion reduces infarct size in a porcine myocardial infarction model. Int. J. Mol. Med. 27(6), 775-781 (2011).
-
(2011)
Int. J. Mol. Med.
, vol.27
, Issue.6
, pp. 775-781
-
-
Debinski, M.1
Buszman, P.P.2
Milewski, K.3
-
63
-
-
19944369735
-
Adiponectin-mediated modulation of hypertrophic signals in the heart
-
DOI 10.1038/nm1137
-
Shibata R, Ouchi N, Ito M et al. Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat. Med. 10(12), 1384-1389 (2004). (Pubitemid 40022722)
-
(2004)
Nature Medicine
, vol.10
, Issue.12
, pp. 1384-1389
-
-
Shibata, R.1
Ouchi, N.2
Ito, M.3
Kihara, S.4
Shiojima, I.5
Pimentel, D.R.6
Kumada, M.7
Sato, K.8
Schiekofer, S.9
Ohashi, K.10
Funahashi, T.11
Colucci, W.S.12
Walsh, K.13
-
64
-
-
34249869321
-
Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes
-
DOI 10.1016/j.cardiores.2007.04.011, PII S0008636307001897
-
Palanivel R, Fang X, Park M et al. Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes. Cardiovasc. Res. 75(1), 148-157 (2007). (Pubitemid 46873521)
-
(2007)
Cardiovascular Research
, vol.75
, Issue.1
, pp. 148-157
-
-
Palanivel, R.1
Fang, X.2
Park, M.3
Eguchi, M.4
Pallan, S.5
De Girolamo, S.6
Liu, Y.7
Wang, Y.8
Xu, A.9
Sweeney, G.10
-
65
-
-
78650841146
-
Adiponectin increases LPL activity via RhoA/ROCK-mediated actin remodelling in adult rat cardiomyocytes
-
Ganguly R, Schram K, Fang X et al. Adiponectin increases LPL activity via RhoA/ROCK-mediated actin remodelling in adult rat cardiomyocytes. Endocrinology 152(1), 247-254 (2010).
-
(2010)
Endocrinology
, vol.152
, Issue.1
, pp. 247-254
-
-
Ganguly, R.1
Schram, K.2
Fang, X.3
-
66
-
-
78349254663
-
An APPL1-AMPK signaling axis mediates beneficial metabolic effects of adiponectin in the heart
-
Fang X, Palanivel R, Cresser J et al. An APPL1-AMPK signaling axis mediates beneficial metabolic effects of adiponectin in the heart. Am. J. Physiol. Endocrinol. Metab. 299(5), E721-E729 (2010).
-
(2010)
Am. J. Physiol. Endocrinol. Metab.
, vol.299
, Issue.5
-
-
Fang, X.1
Palanivel, R.2
Cresser, J.3
-
67
-
-
79959360734
-
Adiponectin as a regulator of vascular redox state: Therapeutic implications
-
Antonopoulos AS, Lee R, Margaritis M, Antoniades C. Adiponectin as a regulator of vascular redox state: therapeutic implications. Recent Pat. Cardiovasc. Drug Discov. 6(2), 78-88 (2011).
-
(2011)
Recent Pat. Cardiovasc. Drug Discov.
, vol.6
, Issue.2
, pp. 78-88
-
-
Antonopoulos, A.S.1
Lee, R.2
Margaritis, M.3
Antoniades, C.4
-
68
-
-
79953329339
-
High level of plasma adiponectin in acute stroke patients is associated with stroke mortality
-
Nagasawa H, Yokota C, Toyoda K, Ito A, Minematsu K. High level of plasma adiponectin in acute stroke patients is associated with stroke mortality. J. Neurol. Sci. 304(1-2), 102-106 (2011).
-
(2011)
J. Neurol. Sci.
, vol.304
, Issue.1-2
, pp. 102-106
-
-
Nagasawa, H.1
Yokota, C.2
Toyoda, K.3
Ito, A.4
Minematsu, K.5
-
69
-
-
35948959366
-
Total and high molecular weight but not trimeric or hexameric forms of adiponectin correlate with markers of the metabolic syndrome and liver injury in Thai subjects
-
DOI 10.1210/jc.2007-0890
-
Liu Y, Retnakaran R, Hanley A, Tungtrongchitr R, Shaw C, Sweeney G. Total and high molecular weight but not trimeric or hexameric forms of adiponectin correlate with markers of the metabolic syndrome and liver injury in Thai subjects. J. Clin. Endocrinol. Metab. 92(11), 4313-4318 (2007). (Pubitemid 350074750)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.11
, pp. 4313-4318
-
-
Liu, Y.1
Retnakaran, R.2
Hanley, A.3
Tungtrongchitr, R.4
Shaw, C.5
Sweeney, G.6
-
70
-
-
65349162789
-
Adiponectin in health and disease: Evaluation of adiponectin-targeted drug development strategies
-
Shetty S, Kusminski CM, Scherer PE. Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies. Trends Pharmacol. Sci. 30(5), 234-239 (2009).
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, Issue.5
, pp. 234-239
-
-
Shetty, S.1
Kusminski, C.M.2
Scherer, P.E.3
-
71
-
-
11144346107
-
Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome
-
DOI 10.1161/01.CIR.0000150391.38660.9B
-
Salmenniemi U, Ruotsalainen E, Pihlajamaki J et al. Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome. Circulation 110(25), 3842-3848 (2004). (Pubitemid 40023983)
-
(2004)
Circulation
, vol.110
, Issue.25
, pp. 3842-3848
-
-
Salmenniemi, U.1
Ruotsalainen, E.2
Pihlajamaki, J.3
Vauhkonen, I.4
Kainulainen, S.5
Punnonen, K.6
Vanninen, E.7
Laakso, M.8
-
72
-
-
15944425403
-
Adiponectinemia in visceral obesity: Impact on glucose tolerance and plasma lipoprotein and lipid levels in men
-
DOI 10.1210/jc.2004-1711
-
Cote M, Mauriege P, Bergeron J et al. Adiponectinemia in visceral obesity: impact on glucose tolerance and plasma lipoprotein and lipid levels in men. J. Clin. Endocrinol. Metab. 90(3), 1434-1439 (2005). (Pubitemid 40464000)
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, Issue.3
, pp. 1434-1439
-
-
Cote, M.1
Mauriege, P.2
Bergeron, J.3
Almeras, N.4
Tremblay, A.5
Lemieux, I.6
Despres, J.-P.7
-
73
-
-
0030935652
-
Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The da Qing IGT and Diabetes Study
-
Pan XR, Li GW, Hu YH et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care 20(4), 537-544 (1997).
-
(1997)
Diabetes Care
, vol.20
, Issue.4
, pp. 537-544
-
-
Pan, X.R.1
Li, G.W.2
Hu, Y.H.3
-
74
-
-
0035799806
-
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
-
DOI 10.1056/NEJM200105033441801
-
Tuomilehto J, Lindstrom J, Eriksson JG et al. Prevention of Type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N. Engl. J. Med. 344(18), 1343-1350 (2001). (Pubitemid 32378388)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.18
, pp. 1343-1350
-
-
Tuomilehto, J.1
Lindstrom, J.2
Eriksson, J.G.3
Valle, T.T.4
Hamalainen, H.5
Ianne-Parikka, P.6
Keinanen-Kiukaanniemi, S.7
Laakso, M.8
Louheranta, A.9
Rastas, M.10
Salminen, V.11
Uusitupa, M.12
-
75
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
DOI 10.1056/NEJMoa012512
-
Knowler WC, Barrett-Connor E, Fowler SE et al. Reduction in the incidence of Type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 346(6), 393-403 (2002). (Pubitemid 34437694)
-
(2002)
New England Journal of Medicine
, vol.346
, Issue.6
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
Hamman, R.F.4
Lachin, J.M.5
Walker, E.A.6
Nathan, D.M.7
-
76
-
-
15944424370
-
Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes prevention program
-
DOI 10.2337/diacare.28.4.888
-
Ratner R, Goldberg R, Haffner S et al. Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes prevention program. Diabetes Care 28(4), 888-894 (2005). (Pubitemid 40434491)
-
(2005)
Diabetes Care
, vol.28
, Issue.4
, pp. 888-894
-
-
Ratner, R.1
Goldberg, R.2
Haffner, S.3
Marcovina, S.4
Orchard, T.5
Fowler, S.6
Temprosa, M.7
-
77
-
-
58149471799
-
Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: Associations with changes in metabolic risk factors
-
Di Marzo V, Cote M, Matias I et al. Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors. Diabetologia 52(2), 213-217 (2009).
-
(2009)
Diabetologia
, vol.52
, Issue.2
, pp. 213-217
-
-
Di Marzo, V.1
Cote, M.2
Matias, I.3
-
78
-
-
61949365497
-
Prevention of insulin resistance by n-3 polyunsaturated fatty acids
-
Fedor D, Kelley DS. Prevention of insulin resistance by n-3 polyunsaturated fatty acids. Curr. Opin. Clin. Nutr. Metab. Care 12(2), 138-146 (2009).
-
(2009)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.12
, Issue.2
, pp. 138-146
-
-
Fedor, D.1
Kelley, D.S.2
-
79
-
-
61949464059
-
Omega-6 fatty acids and risk for cardiovascular disease: A science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; And Council on Epidemiology and Prevention
-
Harris WS, Mozaffarian D, Rimm E et al. Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Circulation 119(6), 902-907 (2009).
-
(2009)
Circulation
, vol.119
, Issue.6
, pp. 902-907
-
-
Harris, W.S.1
Mozaffarian, D.2
Rimm, E.3
-
80
-
-
78650012956
-
N-6 fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: A meta-analysis of randomised controlled trials
-
Ramsden CE, Hibbeln JR, Majchrzak SF, Davis JM. n-6 fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: a meta-analysis of randomised controlled trials. Br. J. Nutr. 104(11), 1586-1600 (2010).
-
(2010)
Br. J. Nutr.
, vol.104
, Issue.11
, pp. 1586-1600
-
-
Ramsden, C.E.1
Hibbeln, J.R.2
Majchrzak, S.F.3
Davis, J.M.4
-
81
-
-
77956471187
-
Therapies for Type 2 diabetes: Lowering HbA1c and associated cardiovascular risk factors
-
Kurukulasuriya LR, Sowers JR. Therapies for Type 2 diabetes: lowering HbA1c and associated cardiovascular risk factors. Cardiovasc. Diabetol. 9, 45 (2010).
-
(2010)
Cardiovasc. Diabetol.
, vol.9
, pp. 45
-
-
Kurukulasuriya, L.R.1
Sowers, J.R.2
-
82
-
-
34147136507
-
Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice
-
DOI 10.1194/jlr.C600025-JLR200
-
Graham MJ, Lemonidis KM, Whipple CP et al. Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice. J. Lipid Res. 48(4), 763-767 (2007). (Pubitemid 46557881)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.4
, pp. 763-767
-
-
Graham, M.J.1
Lemonidis, K.M.2
Whipple, C.P.3
Subramaniam, A.4
Monia, B.P.5
Crooke, S.T.6
Crooke, R.M.7
-
83
-
-
50149101511
-
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
-
Frank-Kamenetsky M, Grefhorst A, Anderson NN et al. Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. Proc. Natl Acad. Sci. USA 105(33), 11915-11920 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.33
, pp. 11915-11920
-
-
Frank-Kamenetsky, M.1
Grefhorst, A.2
Anderson, N.N.3
-
84
-
-
58149200174
-
Molecule of the month. TREDAPTIVE (nicotinic acid/ laropiprant): A new lipid-modifying therapy for the treatment of LDL-C, HDL-C and triglycerides
-
Felts AS. Molecule of the month. TREDAPTIVE (nicotinic acid/ laropiprant): a new lipid-modifying therapy for the treatment of LDL-C, HDL-C and triglycerides. Curr. Top. Med. Chem. 8(14), 1310 (2008).
-
(2008)
Curr. Top. Med. Chem.
, vol.8
, Issue.14
, pp. 1310
-
-
Felts, A.S.1
-
85
-
-
78651345748
-
New anticoagulant agents in acute coronary syndromes
-
Hochtl T, Farhan S, Wojta J, Huber K. New anticoagulant agents in acute coronary syndromes. Heart 97(3), 244-252 (2011).
-
(2011)
Heart
, vol.97
, Issue.3
, pp. 244-252
-
-
Hochtl, T.1
Farhan, S.2
Wojta, J.3
Huber, K.4
-
86
-
-
58149312852
-
Prasugrel: A new antiplatelet drug for the prevention and treatment of cardiovascular disease
-
Koo MH, Nawarskas JJ, Frishman WH. Prasugrel: a new antiplatelet drug for the prevention and treatment of cardiovascular disease. Cardiol. Rev. 16(6), 314-318 (2008).
-
(2008)
Cardiol. Rev.
, vol.16
, Issue.6
, pp. 314-318
-
-
Koo, M.H.1
Nawarskas, J.J.2
Frishman, W.H.3
-
87
-
-
70149101223
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
-
Wallentin L, Becker RC, Budaj A et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N. Engl. J. Med. 361(11), 1045-1057 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, Issue.11
, pp. 1045-1057
-
-
Wallentin, L.1
Becker, R.C.2
Budaj, A.3
-
88
-
-
62949141274
-
Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) trial
-
James S, Akerblom A, Cannon CP et al. Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) trial. Am. Heart J. 157(4), 599-605 (2009).
-
(2009)
Am. Heart J.
, vol.157
, Issue.4
, pp. 599-605
-
-
James, S.1
Akerblom, A.2
Cannon, C.P.3
-
89
-
-
77956817833
-
Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi
-
Gu J, Noe A, Chandra P et al. Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi). J. Clin. Pharmacol. 50(4), 401-414 (2010).
-
(2010)
J. Clin. Pharmacol.
, vol.50
, Issue.4
, pp. 401-414
-
-
Gu, J.1
Noe, A.2
Chandra, P.3
-
90
-
-
77950628157
-
Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: A randomised, double-blind, placebo-controlled, active comparator study
-
Ruilope LM, Dukat A, Bohm M, Lacourciere Y, Gong J, Lefkowitz MP. Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study. Lancet 375(9722), 1255-1266 (2010).
-
(2010)
Lancet
, vol.375
, Issue.9722
, pp. 1255-1266
-
-
Ruilope, L.M.1
Dukat, A.2
Bohm, M.3
Lacourciere, Y.4
Gong, J.5
Lefkowitz, M.P.6
-
91
-
-
77957064963
-
Mipomersen as a potential adjunctive therapy for hypercholesterolemia
-
Patel N, Hegele RA. Mipomersen as a potential adjunctive therapy for hypercholesterolemia. Expert. Opin. Pharmacother. 11(15), 2569-2572 (2010).
-
(2010)
Expert. Opin. Pharmacother.
, vol.11
, Issue.15
, pp. 2569-2572
-
-
Patel, N.1
Hegele, R.A.2
-
92
-
-
77954738952
-
Impact of GLP-1 and GLP-1 receptor agonists on cardiovascular risk factors in Type 2 diabetes
-
Verge D, Lopez X. Impact of GLP-1 and GLP-1 receptor agonists on cardiovascular risk factors in Type 2 diabetes. Curr. Diabetes Rev. 6(4), 191-200 (2010).
-
(2010)
Curr. Diabetes Rev.
, vol.6
, Issue.4
, pp. 191-200
-
-
Verge, D.1
Lopez, X.2
-
93
-
-
78650733949
-
Cardiovascular comorbidities of Type 2 diabetes mellitus: Defining the potential of glucagonlike peptide-1-based therapies
-
Chilton R, Wyatt J, Nandish S, Oliveros R, Lujan M. Cardiovascular comorbidities of Type 2 diabetes mellitus: defining the potential of glucagonlike peptide-1-based therapies. Am. J. Med. 124(1 Suppl.), S35-S53 (2011).
-
(2011)
Am. J. Med.
, vol.124
, Issue.1 SUPPL.
-
-
Chilton, R.1
Wyatt, J.2
Nandish, S.3
Oliveros, R.4
Lujan, M.5
-
94
-
-
84988043834
-
Coronary heart disease: New hope for CETP inhibitors
-
King A. Coronary heart disease: new hope for CETP inhibitors. Nat. Rev. Cardiol. 8(1), 5 (2011).
-
(2011)
Nat. Rev. Cardiol.
, vol.8
, Issue.1
, pp. 5
-
-
King, A.1
-
95
-
-
77957873829
-
Update on inhibition
-
Davidson MH. Update on inhibition. J. Clin. Lipidol. 4(5), 394-398 (2010).
-
(2010)
J. Clin. Lipidol.
, vol.4
, Issue.5
, pp. 394-398
-
-
Davidson, M.H.1
-
96
-
-
70350560562
-
Metabolomics applied to diabetes research: Moving from information to knowledge
-
Bain JR, Stevens RD, Wenner BR, Ilkayeva O, Muoio DM, Newgard CB. Metabolomics applied to diabetes research: moving from information to knowledge. Diabetes 58(11), 2429-2443 (2009).
-
(2009)
Diabetes
, vol.58
, Issue.11
, pp. 2429-2443
-
-
Bain, J.R.1
Stevens, R.D.2
Wenner, B.R.3
Ilkayeva, O.4
Muoio, D.M.5
Newgard, C.B.6
-
97
-
-
45849145091
-
Application of Metabolomics to Cardiovascular Biomarker and Pathway Discovery
-
DOI 10.1016/j.jacc.2008.03.043, PII S073510970801440X
-
Lewis GD, Asnani A, Gerszten RE. Application of metabolomics to cardiovascular biomarker and pathway discovery. J. Am. Coll. Cardiol. 52(2), 117-123 (2008). (Pubitemid 351885452)
-
(2008)
Journal of the American College of Cardiology
, vol.52
, Issue.2
, pp. 117-123
-
-
Lewis, G.D.1
Asnani, A.2
Gerszten, R.E.3
-
98
-
-
54849439476
-
New insights into cardiovascular and lipid metabolomics
-
Giovane A, Balestrieri A, Napoli C. New insights into cardiovascular and lipid metabolomics. J. Cell. Biochem. 105(3), 648-654 (2008).
-
(2008)
J. Cell. Biochem.
, vol.105
, Issue.3
, pp. 648-654
-
-
Giovane, A.1
Balestrieri, A.2
Napoli, C.3
-
99
-
-
77955013277
-
Disease prevention - Should we target obesity or sedentary lifestyle?
-
Charansonney OL, Despres JP. Disease prevention - should we target obesity or sedentary lifestyle? Nat. Rev. Cardiol. 7(8), 468-472 (2010).
-
(2010)
Nat. Rev. Cardiol.
, vol.7
, Issue.8
, pp. 468-472
-
-
Charansonney, O.L.1
Despres, J.P.2
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