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Volumn 87, Issue 4, 2010, Pages 407-416

Obesity, inflammation, and cardiovascular risk

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN; INTERLEUKIN 6; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TUMOR NECROSIS FACTOR ALPHA;

EID: 77949874469     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2009.311     Document Type: Review
Times cited : (334)

References (57)
  • 1
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • Després, J.P. & Lemieux, I. Abdominal obesity and metabolic syndrome. Nature 444, 881-887 (2006).
    • (2006) Nature , vol.444 , pp. 881-887
    • Després, J.P.1    Lemieux, I.2
  • 3
    • 33846970555 scopus 로고    scopus 로고
    • Metabolic syndrome: A multiplex cardiovascular risk factor
    • Grundy, S.M. Metabolic syndrome: a multiplex cardiovascular risk factor. J. Clin. Endocrinol. Metab. 92, 399-404 (2007).
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 399-404
    • Grundy, S.M.1
  • 4
    • 70450189795 scopus 로고    scopus 로고
    • Infammation in atherosclerosis: From pathophysiology to practice
    • Libby, P., Ridker, P.M. & Hansson, G.K. Infammation in atherosclerosis: from pathophysiology to practice. J. Am. Coll. Cardiol. 54, 2129-2138 (2009).
    • (2009) J. Am. Coll. Cardiol. , vol.54 , pp. 2129-2138
    • Libby, P.1    Ridker, P.M.2    Hansson, G.K.3
  • 5
    • 33644822875 scopus 로고
    • Visceral obesity: A "civilization syndrome"
    • Björntorp, P. Visceral obesity: a "civilization syndrome". Obes. Res. 1, 206-222 (1993).
    • (1993) Obes. Res. , vol.1 , pp. 206-222
    • Björntorp, P.1
  • 6
    • 14544279805 scopus 로고    scopus 로고
    • Longevity lipotoxicity and leptin: The adipocyte defense against feasting and famine
    • Unger, R.H. Longevity, lipotoxicity and leptin: the adipocyte defense against feasting and famine. Biochimie 87, 57-64 (2005).
    • (2005) Biochimie , vol.87 , pp. 57-64
    • Unger, R.H.1
  • 7
    • 0348141010 scopus 로고    scopus 로고
    • Infammation and cardiovascular disease: Is abdominal obesity the missing link?
    • Després, J.P. Infammation and cardiovascular disease: is abdominal obesity the missing link? Int. J. Obes. Relat. Metab. Disord. 27 (suppl. 3), S22-S24 (2003).
    • (2003) Int. J. Obes. Relat. Metab. Disord. , vol.27 , Issue.SUPPL. 3
    • Després, J.P.1
  • 8
    • 43249100772 scopus 로고    scopus 로고
    • Visceral obesity and plasma glucose-insulin homeostasis: Contributions of interleukin-6 and tumor necrosis factor-alpha in men
    • Cartier, A., Lemieux, I., Alméras, N., Tremblay, A., Bergeron, J. & Després, J.P. Visceral obesity and plasma glucose-insulin homeostasis: contributions of interleukin-6 and tumor necrosis factor-alpha in men. J. Clin. Endocrinol. Metab. 93, 1931-1938 (2008).
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 1931-1938
    • Cartier, A.1    Lemieux, I.2    Alméras, N.3    Tremblay, A.4    Bergeron, J.5    Després, J.P.6
  • 9
    • 33846821855 scopus 로고    scopus 로고
    • Postprandial variations of plasma infammatory markers in abdominally obese men
    • Blackburn, P. et al. Postprandial variations of plasma infammatory markers in abdominally obese men. Obesity 14, 1747-1754 (2006).
    • (2006) Obesity , vol.14 , pp. 1747-1754
    • Blackburn, P.1
  • 10
    • 44849132591 scopus 로고    scopus 로고
    • Dynamics of fat cell turnover in humans
    • Spalding, K.L. et al. Dynamics of fat cell turnover in humans. Nature. 453, 783-787 (2008).
    • (2008) Nature. , vol.453 , pp. 783-787
    • Spalding, K.L.1
  • 12
    • 33646572904 scopus 로고    scopus 로고
    • The metabolic syndrome and adipocytokines
    • Matsuzawa, Y. The metabolic syndrome and adipocytokines. FEBS Lett. 580, 2917-2921 (2006).
    • (2006) FEBS Lett. , vol.580 , pp. 2917-2921
    • Matsuzawa, Y.1
  • 14
    • 33747806291 scopus 로고    scopus 로고
    • Metabolic syndrome: The danger signal in atherosclerosis
    • Mathieu, P., Pibarot, P. & Després, J.P. Metabolic syndrome: the danger signal in atherosclerosis. Vasc. Health Risk Manag. 2, 285-302 (2006).
    • (2006) Vasc. Health Risk Manag. , vol.2 , pp. 285-302
    • Mathieu, P.1    Pibarot, P.2    Després, J.P.3
  • 15
    • 36849005372 scopus 로고    scopus 로고
    • A subpopulation of macrophages infltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
    • Nguyen, M.T. et al. A subpopulation of macrophages infltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J. Biol. Chem. 282, 35279-35292 (2007).
    • (2007) J. Biol. Chem. , vol.282 , pp. 35279-35292
    • Nguyen, M.T.1
  • 16
    • 0037101934 scopus 로고    scopus 로고
    • Metabolic efects of interleukin-6 in human splanchnic and adipose tissue
    • Lyngsø, D., Simonsen, L. & Bülow, J. Metabolic efects of interleukin-6 in human splanchnic and adipose tissue. J. Physiol. 543 (Pt 1), 379-386 (2002).
    • (2002) J. Physiol. , vol.543 , Issue.PART 1 , pp. 379-386
    • Lyngsø, D.1    Simonsen, L.2    Bülow, J.3
  • 18
    • 54849404394 scopus 로고    scopus 로고
    • The quest for the optimal assessment of global cardiovascular risk: Are traditional risk factors and metabolic syndrome partners in crime?
    • Arsenault, B.J., Pibarot, P. & Després, J.P. The quest for the optimal assessment of global cardiovascular risk: are traditional risk factors and metabolic syndrome partners in crime? Cardiology 113, 35-49 (2009).
    • (2009) Cardiology , vol.113 , pp. 35-49
    • Arsenault, B.J.1    Pibarot, P.2    Després, J.P.3
  • 19
    • 0141835079 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein and cardiovascular risk: Rationale for screening and primary prevention
    • Ridker, P.M. High-sensitivity C-reactive protein and cardiovascular risk: rationale for screening and primary prevention. Am. J. Cardiol. 92, 17K-22K (2003).
    • (2003) Am. J. Cardiol. , vol.92
    • Ridker, P.M.1
  • 20
    • 67649385758 scopus 로고    scopus 로고
    • Body composition, cardiorespiratory ftness, and low-grade infammation in middle-aged men and women
    • Arsenault, B.J. et al. Body composition, cardiorespiratory ftness, and low-grade infammation in middle-aged men and women. Am. J. Cardiol. 104, 240-246 (2009).
    • (2009) Am. J. Cardiol. , vol.104 , pp. 240-246
    • Arsenault, B.J.1
  • 21
    • 33747193034 scopus 로고    scopus 로고
    • Gender and C-reactive protein: Data from the Multiethnic Study of Atherosclerosis (MESA) cohort
    • Lakoski, S.G. et al. Gender and C-reactive protein: data from the Multiethnic Study of Atherosclerosis (MESA) cohort. Am. Heart J. 152, 593-598 (2006).
    • (2006) Am. Heart J. , vol.152 , pp. 593-598
    • Lakoski, S.G.1
  • 22
    • 74249097743 scopus 로고    scopus 로고
    • Rosiglitazone decreases C-reactive protein to a greater extent relative to glyburide and metformin over 4 years despite greater weight gain: Observations from a Diabetes Outcome Progression Trial (ADOPT)
    • Kahn, S.E. et al. Rosiglitazone decreases C-reactive protein to a greater extent relative to glyburide and metformin over 4 years despite greater weight gain: observations from a Diabetes Outcome Progression Trial (ADOPT). Diabetes Care 33, 177-183 (2010).
    • (2010) Diabetes Care , vol.33 , pp. 177-183
    • Kahn, S.E.1
  • 23
    • 9144264915 scopus 로고    scopus 로고
    • C-reactive protein: An activator of innate immunity and a modulator of adaptive immunity
    • Du Clos, T.W. & Mold, C. C-reactive protein: an activator of innate immunity and a modulator of adaptive immunity. Immunol. Res. 30, 261-277 (2004).
    • (2004) Immunol. Res. , vol.30 , pp. 261-277
    • Du Clos, T.W.1    Mold, C.2
  • 24
    • 0037469261 scopus 로고    scopus 로고
    • C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: Implications for the metabolic syndrome and atherothrombosis
    • Devaraj, S., Xu, D.Y. & Jialal, I. C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: implications for the metabolic syndrome and atherothrombosis. Circulation 107, 398-404 (2003).
    • (2003) Circulation , vol.107 , pp. 398-404
    • Devaraj, S.1    Xu, D.Y.2    Jialal, I.3
  • 25
    • 0018861450 scopus 로고
    • Cell-mediated immunity in genetically obese C57BL/6J ob/ob) mice
    • Chandra, R.K. Cell-mediated immunity in genetically obese C57BL/6J ob/ob) mice. Am. J. Clin. Nutr. 33, 13-16 (1980).
    • (1980) Am. J. Clin. Nutr. , vol.33 , pp. 13-16
    • Chandra, R.K.1
  • 26
    • 0035909997 scopus 로고    scopus 로고
    • Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS)
    • Wallace, A.M. et al. Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS). Circulation 104, 3052-3056 (2001).
    • (2001) Circulation , vol.104 , pp. 3052-3056
    • Wallace, A.M.1
  • 27
    • 0031735742 scopus 로고    scopus 로고
    • Leptinemia is not a risk factor for ischemic heart disease in men
    • Prospective results from the Quebec Cardiovascular Study
    • Couillard, C. et al. Leptinemia is not a risk factor for ischemic heart disease in men. Prospective results from the Quebec Cardiovascular Study. Diabetes Care 21, 782-786 (1998).
    • (1998) Diabetes Care , vol.21 , pp. 782-786
    • Couillard, C.1
  • 28
    • 0033613545 scopus 로고    scopus 로고
    • Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
    • Ouchi, N. et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 100, 2473-2476 (1999).
    • (1999) Circulation , vol.100 , pp. 2473-2476
    • Ouchi, N.1
  • 29
    • 15944425403 scopus 로고    scopus 로고
    • Adiponectinemia in visceral obesity: Impact on glucose tolerance and plasma lipoprotein and lipid levels in men
    • Côté, M. et al. Adiponectinemia in visceral obesity: impact on glucose tolerance and plasma lipoprotein and lipid levels in men. J. Clin. Endocrinol. Metab. 90, 1434-1439 (2005).
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 1434-1439
    • Côté, M.1
  • 31
    • 44449161687 scopus 로고    scopus 로고
    • Association of adiponectin with adverse outcome in coronary artery disease patients: Results from the AtheroGene study
    • Schnabel, R. et al. Association of adiponectin with adverse outcome in coronary artery disease patients: results from the AtheroGene study. Eur. Heart J. 29, 649-657 (2008).
    • (2008) Eur. Heart J. , vol.29 , pp. 649-657
    • Schnabel, R.1
  • 32
    • 0242641149 scopus 로고    scopus 로고
    • Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists
    • Way, J.M. et al. Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists. J. Biol. Chem. 276, 25651-25653 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 25651-25653
    • Way, J.M.1
  • 33
    • 34247639924 scopus 로고    scopus 로고
    • The contribution of adipose tissue and adipokines to infammation in joint diseases
    • Toussirot, E., Streit, G. & Wendling, D. The contribution of adipose tissue and adipokines to infammation in joint diseases. Curr. Med. Chem. 14, 1095-1100 (2007).
    • (2007) Curr. Med. Chem. , vol.14 , pp. 1095-1100
    • Toussirot, E.1    Streit, G.2    Wendling, D.3
  • 35
    • 77953536146 scopus 로고    scopus 로고
    • Age-related diferences in the pathogenesis of calcifc aortic stenosis: The potential role of resistin
    • e-pub ahead of print 20 January 2009
    • Mohty, D. et al. Age-related diferences in the pathogenesis of calcifc aortic stenosis: the potential role of resistin. Int. J. Cardiol. (2009); e-pub ahead of print 20 January 2009.
    • (2009) Int. J. Cardiol.
    • Mohty, D.1
  • 36
    • 23244451031 scopus 로고    scopus 로고
    • Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-defcient mice
    • Babaev, V.R. et al. Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-defcient mice. Arterioscler. Thromb. Vasc. Biol. 25, 1647-1653 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 1647-1653
    • Babaev, V.R.1
  • 37
    • 0033965557 scopus 로고    scopus 로고
    • Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice
    • Gavrilova, O. et al. Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice. J. Clin. Invest. 105, 271-278 (2000).
    • (2000) J. Clin. Invest. , vol.105 , pp. 271-278
    • Gavrilova, O.1
  • 38
    • 56449105671 scopus 로고    scopus 로고
    • Before they were fat: Adipocyte progenitors
    • Park, K.W., Halperin, D.S. & Tontonoz, P. Before they were fat: adipocyte progenitors. Cell Metab. 8, 454-457 (2008).
    • (2008) Cell Metab. , vol.8 , pp. 454-457
    • Park, K.W.1    Halperin, D.S.2    Tontonoz, P.3
  • 39
    • 0037883037 scopus 로고    scopus 로고
    • Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients
    • Miyazaki, Y., He, H., Mandarino, L.J. & DeFronzo, R.A. Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients. Diabetes 52, 1943-1950 (2003).
    • (2003) Diabetes , vol.52 , pp. 1943-1950
    • Miyazaki, Y.1    He, H.2    Mandarino, L.J.3    Defronzo, R.A.4
  • 40
    • 34548590934 scopus 로고    scopus 로고
    • Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis of randomized trials
    • Lincof, A.M., Wolski, K., Nicholls, S.J. & Nissen, S.E. Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials. JAMA 298, 1180-1188 (2007).
    • (2007) JAMA , vol.298 , pp. 1180-1188
    • Lincof, A.M.1    Wolski, K.2    Nicholls, S.J.3    Nissen, S.E.4
  • 41
    • 0035842484 scopus 로고    scopus 로고
    • Total cholesterol/HDL cholesterol ratio vs LDL cholesterol/ HDL cholesterol ratio as indices of ischemic heart disease risk in men: The Quebec Cardiovascular Study
    • Lemieux, I. et al. Total cholesterol/HDL cholesterol ratio vs LDL cholesterol/ HDL cholesterol ratio as indices of ischemic heart disease risk in men: the Quebec Cardiovascular Study. Arch. Intern. Med. 161, 2685-2692 (2001).
    • (2001) Arch. Intern. Med. , vol.161 , pp. 2685-2692
    • Lemieux, I.1
  • 42
  • 43
    • 6344267152 scopus 로고    scopus 로고
    • Metabolic syndrome is associated with elevated oxidative stress and dysfunctional dense high-density lipoprotein particles displaying impaired antioxidative activity
    • Hansel, B. et al. Metabolic syndrome is associated with elevated oxidative stress and dysfunctional dense high-density lipoprotein particles displaying impaired antioxidative activity. J. Clin. Endocrinol. Metab. 89, 4963-4971 (2004).
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 4963-4971
    • Hansel, B.1
  • 44
    • 36348975228 scopus 로고    scopus 로고
    • Efects of torcetrapib in patients at high risk for coronary events
    • Barter, P.J. et al. Efects of torcetrapib in patients at high risk for coronary events. N. Engl. J. Med. 357, 2109-2122 (2007).
    • (2007) N. Engl. J. Med. , vol.357 , pp. 2109-2122
    • Barter, P.J.1
  • 45
    • 64849088450 scopus 로고    scopus 로고
    • Visceral obesity: The link among infammation, hypertension, and cardiovascular disease
    • Mathieu, P., Poirier, P., Pibarot, P., Lemieux, I. & Després, J.P. Visceral obesity: the link among infammation, hypertension, and cardiovascular disease. Hypertension 53, 577-584 (2009).
    • (2009) Hypertension , vol.53 , pp. 577-584
    • Mathieu, P.1    Poirier, P.2    Pibarot, P.3    Lemieux, I.4    Després, J.P.5
  • 46
    • 4444344499 scopus 로고    scopus 로고
    • Endogenous angiotensin II induces atherosclerotic plaque vulnerability and elicits a Th1 response in ApoE-/-mice
    • Mazzolai, L. et al. Endogenous angiotensin II induces atherosclerotic plaque vulnerability and elicits a Th1 response in ApoE-/-mice. Hypertension 44, 277-282 (2004).
    • (2004) Hypertension , vol.44 , pp. 277-282
    • Mazzolai, L.1
  • 47
    • 14644427817 scopus 로고    scopus 로고
    • Impact of waist circumference on the relationship between blood pressure and insulin: The Quebec Health Survey
    • Poirier, P. et al. Impact of waist circumference on the relationship between blood pressure and insulin: the Quebec Health Survey. Hypertension 45, 363-367 (2005).
    • (2005) Hypertension , vol.45 , pp. 363-367
    • Poirier, P.1
  • 48
    • 67649863789 scopus 로고    scopus 로고
    • Low cardiorespiratory ftness levels and elevated blood pressure: What is the contribution of visceral adiposity?
    • Rhéaume, C. et al. Low cardiorespiratory ftness levels and elevated blood pressure: what is the contribution of visceral adiposity? Hypertension 54, 91-97 (2009).
    • (2009) Hypertension , vol.54 , pp. 91-97
    • Rhéaume, C.1
  • 49
    • 14644395574 scopus 로고    scopus 로고
    • Weight loss and the renin-angiotensin-aldosterone system
    • Engeli, S. et al. Weight loss and the renin-angiotensin-aldosterone system. Hypertension 45, 356-362 (2005).
    • (2005) Hypertension , vol.45 , pp. 356-362
    • Engeli, S.1
  • 50
    • 78651193167 scopus 로고
    • Sexual diferentiation, a factor afecting the forms of obesity
    • Vague, J. Sexual diferentiation, a factor afecting the forms of obesity. Presse. Med. 55, 339 (1947).
    • (1947) Presse. Med. , vol.55 , pp. 339
    • Vague, J.1
  • 51
    • 37349066531 scopus 로고    scopus 로고
    • International Day for the Evaluation of Abdominal Obesity (IDEA): A study of waist circumference, cardiovascular disease, and diabetes mellitus in 168,000 primary care patients in 63 countries
    • Balkau, B. et al. International Day for the Evaluation of Abdominal Obesity (IDEA): a study of waist circumference, cardiovascular disease, and diabetes mellitus in 168,000 primary care patients in 63 countries. Circulation 116, 1942-1951 (2007).
    • (2007) Circulation , vol.116 , pp. 1942-1951
    • Balkau, B.1
  • 52
    • 0034079725 scopus 로고    scopus 로고
    • Visceral adiposity and risk of type 2 diabetes: A prospective study among Japanese Americans
    • Boyko, E.J., Fujimoto, W.Y., Leonetti, D.L. & Newell-Morris, L. Visceral adiposity and risk of type 2 diabetes: a prospective study among Japanese Americans. Diabetes Care 23, 465-471 (2000).
    • (2000) Diabetes Care , vol.23 , pp. 465-471
    • Boyko, E.J.1    Fujimoto, W.Y.2    Leonetti, D.L.3    Newell-Morris, L.4
  • 53
    • 69949093803 scopus 로고    scopus 로고
    • Cytokine and cytokine-like infammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications
    • Goldberg, R.B. Cytokine and cytokine-like infammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications. J. Clin. Endocrinol. Metab. 94, 3171-3182 (2009).
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 3171-3182
    • Goldberg, R.B.1
  • 54
    • 70349484669 scopus 로고    scopus 로고
    • Mechanisms of obesity and related pathology: Linking immune responses to metabolic stress
    • Karalis, K.P., Giannogonas, P., Kodela, E., Koutmani, Y., Zoumakis, M. & Teli, T. Mechanisms of obesity and related pathology: linking immune responses to metabolic stress. FEBS J. 276, 5747-5754 (2009).
    • (2009) FEBS J. , vol.276 , pp. 5747-5754
    • Karalis, K.P.1    Giannogonas, P.2    Kodela, E.3    Koutmani, Y.4    Zoumakis, M.5    Teli, T.6
  • 55
    • 69349102944 scopus 로고    scopus 로고
    • Antiatherosclerotic and anti-insulin resistance efects of adiponectin: Basic and clinical studies
    • Han, S.H., Sakuma, I., Shin, E.K. & Koh, K.K. Antiatherosclerotic and anti-insulin resistance efects of adiponectin: basic and clinical studies. Prog. Cardiovasc. Dis. 52, 126-140 (2009).
    • (2009) Prog. Cardiovasc. Dis. , vol.52 , pp. 126-140
    • Han, S.H.1    Sakuma, I.2    Shin, E.K.3    Koh, K.K.4
  • 57
    • 63649095045 scopus 로고    scopus 로고
    • Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: A prospective study of the JUPITER trial
    • Ridker, P.M. et al. Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet 373, 1175-1182 (2009).
    • (2009) Lancet , vol.373 , pp. 1175-1182
    • Ridker, P.M.1


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