Removal of GABA a receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Leppä, Elli ^a   Linden, Anni Maija ^a   Vekovischeva, Olga Y ^a   Swinny, Jerome D ^b,c   Rantanen, Ville ^d   Toppila, Esko ^e   Höger, Harald ^f   Sieghart, Werner ^f   Wulff, Peer ^g,h   Wisden, William ^g,i   Korpi, Esa R ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

^c UNIVERSITY OF PORTSMOUTH   (United Kingdom)

^d UNIVERSITY OF HELSINKI   (Finland)

^e FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^f MEDICAL UNIVERSITY OF VIENNA   (Austria)

^g UNIVERSITY OF HEIDELBERG   (Germany)

^h UNIVERSITY OF ABERDEEN   (United Kingdom)

ⁱ IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; CRE RECOMBINASE; PARVALBUMIN; TERT BUTYLBICYCLOPHOSPHOROTHIOATE S 35; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 ETHYL 6,7 DIMETHOXY BETA CARBOLINE 3 CARBOXYLIC ACID METHYL ESTER; ANALGESIC AGENT; CARBOLINE DERIVATIVE; METHYL 6,7-DIMETHOXY-4-ETHYL-BETA-CARBOLINE-3-CARBOXYLATE; PYRIDINE DERIVATIVE; ZOLPIDEM;

4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2 SUBUNIT GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; AUTORADIOGRAPHY; BEHAVIOR DISORDER; BINDING SITE; BRAIN REGION; CONTROLLED STUDY; DISEASE SEVERITY; EMOTIONALITY; FEMALE; GABAERGIC TRANSMISSION; GENE DELETION; GENE FUNCTION; LEARNING DISORDER; LOXP SITE; MALE; MOTOR COORDINATION; MOTOR PERFORMANCE; MOUSE; NOCICEPTION; NONHUMAN; PHENOTYPE; PREPULSE INHIBITION; RECEPTOR BINDING; RECEPTOR GENE; SENSORIMOTOR INTEGRATION; STARTLE REFLEX; SYNAPTIC INHIBITION; TRANSGENICS; TREMOR; WEIGHT REDUCTION; WILD TYPE; ANIMAL; ANIMAL BEHAVIOR; BEHAVIOR; BRAIN; CYTOLOGY; DRUG EFFECT; GENE SILENCING; GENETICS; LEARNING; METABOLISM; MOTOR ACTIVITY; NERVE CELL; PHYSIOLOGY; SPECIES DIFFERENCE; TEMPERATURE;

MUS;

ANALGESICS; ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BINDING SITES; BRAIN; CARBOLINES; FEMALE; GAMMA-AMINOBUTYRIC ACID; GENE SILENCING; LEARNING; MALE; MICE; MOTOR ACTIVITY; NEURONS; NOCICEPTION; PARVALBUMINS; PHENOTYPE; PYRIDINES; RECEPTORS, GABA-A; SPATIAL BEHAVIOR; SPECIES SPECIFICITY; TEMPERATURE;

EID: 80052405855     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024159     Document Type: Article

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