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Volumn 137, Issue 4, 1998, Pages 391-400

The role of GABA-A and mitiochondrial diazepam-binding inhibitor receptors on the effects of neurosteroids on food intake in mice

Author keywords

4' Chlordiazepam; Allopregnanolone; Appetite; Dehydroepiandrosterone sulfate; GABA A receptor; Mitochondrial DBI receptor; Neurosteroids; NMDA receptor; Pregnenolone sulfate; Progesterone

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; DIAZEPAM BINDING INHIBITOR; DIZOCILPINE; FLUMAZENIL; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NEUROSTEROID; PRASTERONE SULFATE; PREGNENOLONE SULFATE; TRIAZOLAM; 4 AMINOBUTYRIC ACID A RECEPTOR; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; CELL RECEPTOR; DIAZEPAM BINDING INHIBITOR RECEPTOR; DIAZEPAM-BINDING INHIBITOR RECEPTOR; ELTANOLONE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PREGNENOLONE;

EID: 0031595001     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050635     Document Type: Article
Times cited : (88)

References (58)
  • 1
    • 0027488935 scopus 로고
    • Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indolacetamide and imidazopyridine derivatives
    • Auta J, Romeo E, Kozikowski A, Ma D, Costa E, Guidotti A (1993) Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indolacetamide and imidazopyridine derivatives. J Pharmacol Exp Ther 265: 9649-9656
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 9649-9656
    • Auta, J.1    Romeo, E.2    Kozikowski, A.3    Ma, D.4    Costa, E.5    Guidotti, A.6
  • 2
    • 0024321145 scopus 로고
    • Anticonvulsant profile of the progesterone metabolite 5α-pregnan-3α-ol-20-one
    • Belelli D, Bolger MB, Gee KW (1989) Anticonvulsant profile of the progesterone metabolite 5α-pregnan-3α-ol-20-one. Eur J Pharmacol 166:125-129
    • (1989) Eur J Pharmacol , vol.166 , pp. 125-129
    • Belelli, D.1    Bolger, M.B.2    Gee, K.W.3
  • 3
    • 0030010448 scopus 로고    scopus 로고
    • Potentiation of neuronal NMDA responses induced by dehydroepiandrosterone and its suppression by progesterone: Effects mediated via sigma receptors
    • Bergeron R, De Montigny C, Debonnel G (1996) Potentiation of neuronal NMDA responses induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors. J Neurosci 16:1193-1202
    • (1996) J Neurosci , vol.16 , pp. 1193-1202
    • Bergeron, R.1    De Montigny, C.2    Debonnel, G.3
  • 5
    • 0025918687 scopus 로고
    • Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: Endogenous metabolites of progesterone that are active at the GABA-A receptor
    • Bitran D, Hilvers RJ, Kellogg CK (1991) Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABA-A receptor. Brain Res 561:157-161
    • (1991) Brain Res , vol.561 , pp. 157-161
    • Bitran, D.1    Hilvers, R.J.2    Kellogg, C.K.3
  • 6
    • 0343943881 scopus 로고
    • Blockade of the bioconversion of progesterone to allopregnanolone prevents the anxiolytic effect and potentiation of cortical GABA-A receptor function observed in progesterone-treated overiectomized rats
    • Bitran D, Mcleod D, Shiekh M (1993a) Blockade of the bioconversion of progesterone to allopregnanolone prevents the anxiolytic effect and potentiation of cortical GABA-A receptor function observed in progesterone-treated overiectomized rats. Soc Neurose Abstr 19:373-373
    • (1993) Soc Neurose Abstr , vol.19 , pp. 373-373
    • Bitran, D.1    Mcleod, D.2    Shiekh, M.3
  • 7
    • 0027312304 scopus 로고
    • Anxiolytic effect of progesterone is associated with increases in cortical allopregnanolone and GABA-A receptor function
    • Bitran D, Purdy RH, Kellogg CK (1993b) Anxiolytic effect of progesterone is associated with increases in cortical allopregnanolone and GABA-A receptor function. Pharmacol Biochem Behav 45:423-428
    • (1993) Pharmacol Biochem Behav , vol.45 , pp. 423-428
    • Bitran, D.1    Purdy, R.H.2    Kellogg, C.K.3
  • 8
    • 0028916048 scopus 로고
    • Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABA-A receptors
    • Bitran D, Shiekh M, Mcleod M (1995) Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABA-A receptors. J Neuroendocrinol 7:171-177
    • (1995) J Neuroendocrinol , vol.7 , pp. 171-177
    • Bitran, D.1    Shiekh, M.2    Mcleod, M.3
  • 9
    • 0027155274 scopus 로고
    • Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons
    • Bowlby MR (1993) Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons. Mol Pharmacol 43:813-819
    • (1993) Mol Pharmacol , vol.43 , pp. 813-819
    • Bowlby, M.R.1
  • 10
    • 0029020370 scopus 로고
    • Food palatability and hunger modulated effects of CGS 9896 and CGS 8216 on food intake
    • Chen S-W, Davies MF, Loew GH (1995) Food palatability and hunger modulated effects of CGS 9896 and CGS 8216 on food intake. Pharmacol Biochem Behav 51:499-503
    • (1995) Pharmacol Biochem Behav , vol.51 , pp. 499-503
    • Chen, S.-W.1    Davies, M.F.2    Loew, G.H.3
  • 11
  • 12
    • 0024953480 scopus 로고
    • Benzodiazepine receptor-mediated enhancement and inhibition of taste reactivity, food choice, and intake
    • Cooper SJ (1989) Benzodiazepine receptor-mediated enhancement and inhibition of taste reactivity, food choice, and intake. Ann NY Acad Sci USA 575:321-336
    • (1989) Ann NY Acad Sci USA , vol.575 , pp. 321-336
    • Cooper, S.J.1
  • 14
    • 0016602859 scopus 로고
    • Noninhalational anaesthetics
    • Harper NJ, Simonds AB (eds) Academic Press, New York
    • Davies MF (1975) Noninhalational anaesthetics. In: Harper NJ, Simonds AB (eds) Advances in drug research, vol 10. Academic Press, New York, pp 22-20
    • (1975) Advances in Drug Research , vol.10 , pp. 22-120
    • Davies, M.F.1
  • 16
    • 0025941858 scopus 로고
    • Receptor binding and electrophysiological effects of dehyroepiandrosterone sulfate, an antagonist of the GABA-A receptor
    • Demirgoren S, Majewska MD, Spivak CE, London ED (1991) Receptor binding and electrophysiological effects of dehyroepiandrosterone sulfate, an antagonist of the GABA-A receptor. Neuroscience 45:127-135
    • (1991) Neuroscience , vol.45 , pp. 127-135
    • Demirgoren, S.1    Majewska, M.D.2    Spivak, C.E.3    London, E.D.4
  • 17
    • 0029961348 scopus 로고    scopus 로고
    • Baclofen pretreatment attenuates the suppressant effect of intraperitoneal administration of cholecystokinin (CCK) on food intake in rats
    • Ebenezer IS (1996) Baclofen pretreatment attenuates the suppressant effect of intraperitoneal administration of cholecystokinin (CCK) on food intake in rats. Brain Res Bull 41:269-271
    • (1996) Brain Res Bull , vol.41 , pp. 269-271
    • Ebenezer, I.S.1
  • 18
    • 0028213566 scopus 로고
    • Neurosteroids modulate calcium currents in hippocampal Ca 1 neurons via a pertussis toxin-sensitive G-protein-coupled mechanism
    • Ffrench-Mullen JMH, Danks P, Spencer KT (1994) Neurosteroids modulate calcium currents in hippocampal CA 1 neurons via a pertussis toxin-sensitive G-protein-coupled mechanism. J Neurosci 14:1963-1977
    • (1994) J Neurosci , vol.14 , pp. 1963-1977
    • Ffrench-Mullen, J.M.H.1    Danks, P.2    Spencer, K.T.3
  • 19
    • 0027426171 scopus 로고
    • The influence of estrous cycle on neurosteroid potency at the gamma-aminobutyric acid A receptor complex
    • Finn DA, Gee KW (1993) The influence of estrous cycle on neurosteroid potency at the gamma-aminobutyric acid A receptor complex. J Pharmacol Exp Ther 265:1374-1379
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 1374-1379
    • Finn, D.A.1    Gee, K.W.2
  • 20
    • 0023896577 scopus 로고
    • Dehydroepiandrosterone sulfate improves memory in aging mice
    • Flood JF, Roberts E (1988) Dehydroepiandrosterone sulfate improves memory in aging mice. Brain Res 488:178-181
    • (1988) Brain Res , vol.488 , pp. 178-181
    • Flood, J.F.1    Roberts, E.2
  • 21
    • 0028853687 scopus 로고
    • Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures: The amygdala is by far the most sensitive
    • Flood JF, Morley JE, Roberts E (1995) Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures: the amygdala is by far the most sensitive. Proc Natl Acad Sci USA 92: 10806-10810
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10806-10810
    • Flood, J.F.1    Morley, J.E.2    Roberts, E.3
  • 22
    • 0028801074 scopus 로고
    • A putative receptor for neurosteroids on the GABA-A receptor complex: The pharmacological properties and therapeutic potential of epalons
    • Gee KW, McCauley LD, Lan NC (1995) A putative receptor for neurosteroids on the GABA-A receptor complex: the pharmacological properties and therapeutic potential of epalons. Crit Rev Neurobiol 9:207-227
    • (1995) Crit Rev Neurobiol , vol.9 , pp. 207-227
    • Gee, K.W.1    McCauley, L.D.2    Lan, N.C.3
  • 23
    • 0028981625 scopus 로고
    • 3H]muscimol binding to the GABA-A receptor complex in rat cortex
    • 3H]muscimol binding to the GABA-A receptor complex in rat cortex. Eur J Pharmacol 288:157-162
    • (1995) Eur J Pharmacol , vol.288 , pp. 157-162
    • Goodnough, D.B.1    Hawkinson, J.E.2
  • 24
    • 0023175459 scopus 로고
    • Structure-activity relationships for steroid interaction with the γy-aminobutyric acid receptor complex
    • Harrison NL, Majewska MD, Harrington JW, Barker JL (1987) Structure-activity relationships for steroid interaction with the γy-aminobutyric acid receptor complex. J Pharmacol Exp Ther 241:346-353
    • (1987) J Pharmacol Exp Ther , vol.241 , pp. 346-353
    • Harrison, N.L.1    Majewska, M.D.2    Harrington, J.W.3    Barker, J.L.4
  • 25
    • 0016772374 scopus 로고
    • Physiological variations in the ovarian production of 5α-pregnane derivatives with sedative properties in the rat
    • Holzbauer M (1975) Physiological variations in the ovarian production of 5α-pregnane derivatives with sedative properties in the rat. J Steroid Biochem 6:1307-1310
    • (1975) J Steroid Biochem , vol.6 , pp. 1307-1310
    • Holzbauer, M.1
  • 27
    • 0028149787 scopus 로고
    • Anticonvulsant activity of neurosteroids: Correlation with γ-aminobutyric acid-evoked chloride current potentiation
    • Kokate TG, Svensson BE, Rogawski MA (1994) Anticonvulsant activity of neurosteroids: correlation with γ-aminobutyric acid-evoked chloride current potentiation. J Pharmacol Exp Ther 279:1223-1229
    • (1994) J Pharmacol Exp Ther , vol.279 , pp. 1223-1229
    • Kokate, T.G.1    Svensson, B.E.2    Rogawski, M.A.3
  • 28
    • 0027428732 scopus 로고
    • Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo
    • Korneyev A, Pan BS, Polo A, Romeo E, Guidotti A, Costa E (1993) Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo. J Neurochem 61:1515-1524
    • (1993) J Neurochem , vol.61 , pp. 1515-1524
    • Korneyev, A.1    Pan, B.S.2    Polo, A.3    Romeo, E.4    Guidotti, A.5    Costa, E.6
  • 29
    • 0026628082 scopus 로고
    • Mitochondrial benzodiazepine receptors and the regulation of steroid biosynthesis
    • Krueger KE, Papadopoulos V (1992) Mitochondrial benzodiazepine receptors and the regulation of steroid biosynthesis. Annu Rev Pharmacol Toxicol 32:211-237
    • (1992) Annu Rev Pharmacol Toxicol , vol.32 , pp. 211-237
    • Krueger, K.E.1    Papadopoulos, V.2
  • 30
    • 0028865904 scopus 로고
    • Neurosteroids: A new class of neuromodulators
    • Kulkarni SK, Reddy DS (1995) Neurosteroids: a new class of neuromodulators. Drugs Today 31:433-455
    • (1995) Drugs Today , vol.31 , pp. 433-455
    • Kulkarni, S.K.1    Reddy, D.S.2
  • 32
    • 0028578643 scopus 로고
    • Neuroactive steroid actions at the GABA-A receptor
    • Lan NC, Gee KW (1994) Neuroactive steroid actions at the GABA-A receptor. Horm Behav 28:537-544
    • (1994) Horm Behav , vol.28 , pp. 537-544
    • Lan, N.C.1    Gee, K.W.2
  • 33
    • 0025663879 scopus 로고
    • Steroid regulation of the GABA-A receptor: Ligand binding, chloride transport and behavior
    • Majewska MD (1990) Steroid regulation of the GABA-A receptor: ligand binding, chloride transport and behavior. Ciba Found Symp 153:83-97
    • (1990) Ciba Found Symp , vol.153 , pp. 83-97
    • Majewska, M.D.1
  • 34
    • 0026509649 scopus 로고
    • Neurosteroids endogenous bimodal modulators of the GABA-A receptor, mechanism of action and physiological significance
    • Majewska MD (1992) Neurosteroids endogenous bimodal modulators of the GABA-A receptor, mechanism of action and physiological significance. Prog Neurobiol 38:379-395
    • (1992) Prog Neurobiol , vol.38 , pp. 379-395
    • Majewska, M.D.1
  • 35
    • 0023114555 scopus 로고
    • Pregnenolone sulfate: An endogenous antagonist of the gamma-qminobutyric acid receptor complex in brain
    • Majewska MD, Schwartz RD (1987) Pregnenolone sulfate: An endogenous antagonist of the gamma-qminobutyric acid receptor complex in brain. Brain Res 404:355-360
    • (1987) Brain Res , vol.404 , pp. 355-360
    • Majewska, M.D.1    Schwartz, R.D.2
  • 36
    • 0025166305 scopus 로고
    • Characterization of steroid interactions with γ-aminobutyric acid receptor-gated chloride ion channels: Evidence for multiple steroid recognition sites
    • Marrow AL, Pace JR, Purdy RH, Paul SM (1990) Characterization of steroid interactions with γ-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites. Mol Pharmacol 37:263-270
    • (1990) Mol Pharmacol , vol.37 , pp. 263-270
    • Marrow, A.L.1    Pace, J.R.2    Purdy, R.H.3    Paul, S.M.4
  • 38
    • 0024343524 scopus 로고
    • Pregnenolone sulfate antagonizes GABA-A receptor-mediated currents via s reduction of channel opening frequency
    • Mienville JM, Vicini S (1989) Pregnenolone sulfate antagonizes GABA-A receptor-mediated currents via s reduction of channel opening frequency. Brain Res 489:190-194
    • (1989) Brain Res , vol.489 , pp. 190-194
    • Mienville, J.M.1    Vicini, S.2
  • 40
    • 0026649978 scopus 로고
    • Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: Regulation by mitochondrial diazepam binding inhibitor receptor
    • Papadopoulos V, Guarneri P, Krueger KE, Guidotti A, Costa E (1992) Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by mitochondrial diazepam binding inhibitor receptor. Proc Natl Acad Sci USA 89:45113-45117
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 45113-45117
    • Papadopoulos, V.1    Guarneri, P.2    Krueger, K.E.3    Guidotti, A.4    Costa, E.5
  • 41
    • 0026579057 scopus 로고
    • Neuroactive steroids
    • Paul SM, Purdy RH (1992) Neuroactive steroids. FASEB J 6:2311-2322
    • (1992) FASEB J , vol.6 , pp. 2311-2322
    • Paul, S.M.1    Purdy, R.H.2
  • 42
    • 0026578047 scopus 로고
    • Steroid modulation of the strychnine-sensitive glycine receptor
    • Prince RJ, Simmonds MA (1992) Steroid modulation of the strychnine-sensitive glycine receptor. Neuropharmacology 31: 201-205
    • (1992) Neuropharmacology , vol.31 , pp. 201-205
    • Prince, R.J.1    Simmonds, M.A.2
  • 43
    • 0027498253 scopus 로고
    • 3H]flunitrazepam binding suggests more than one class of binbing site for steroids at GABA-A receptors
    • 3H]flunitrazepam binding suggests more than one class of binbing site for steroids at GABA-A receptors. Neuropharmacology 32:59-63
    • (1993) Neuropharmacology , vol.32 , pp. 59-63
    • Prince, R.J.1    Simmonds, M.A.2
  • 44
    • 0025882098 scopus 로고
    • Stress-induced elevations of γ-aminobutyric acid type-A active steroids in rat brain
    • Purdy RH, Morrow AL, Moore PH Jr, Paul SM (1991) Stress-induced elevations of γ-aminobutyric acid type-A active steroids in rat brain. Proc Natl Acad Sci USA 88:4553-4557
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4553-4557
    • Purdy, R.H.1    Morrow, A.L.2    Moore Jr., P.H.3    Paul, S.M.4
  • 45
    • 0029852005 scopus 로고    scopus 로고
    • Role of GABA-A and mitochondrial diazepam binding inhibitor receptors in the antistress activity of neurosteroids in mice
    • Reddy DS, Kulkarni SK (1996) Role of GABA-A and mitochondrial diazepam binding inhibitor receptors in the antistress activity of neurosteroids in mice. Psychopharmacology 128:280-292
    • (1996) Psychopharmacology , vol.128 , pp. 280-292
    • Reddy, D.S.1    Kulkarni, S.K.2
  • 46
    • 0030896347 scopus 로고    scopus 로고
    • Differential anxiolytic effects of neurosteroids in the mirrored chamber behavior test in mice
    • Reddy DS, Kulkarni SK (1997a) Differential anxiolytic effects of neurosteroids in the mirrored chamber behavior test in mice. Brain Res 752:61-71
    • (1997) Brain Res , vol.752 , pp. 61-71
    • Reddy, D.S.1    Kulkarni, S.K.2
  • 47
    • 0030859694 scopus 로고    scopus 로고
    • Chronic neurosteroid treatment prevents development of morphine tolerance and attenuates abstinence behavior in mice
    • Reddy DS, Kulkarni SK (1997b) Chronic neurosteroid treatment prevents development of morphine tolerance and attenuates abstinence behavior in mice. Eur J Pharmacol 337:19-25
    • (1997) Eur J Pharmacol , vol.337 , pp. 19-25
    • Reddy, D.S.1    Kulkarni, S.K.2
  • 48
    • 0030782071 scopus 로고    scopus 로고
    • Neurosteroid coadministration prevents development of tolerance and augments recovery from benzodiazepine withdrawal anxiety and hyperactivity in mice
    • Reddy DS, Kulkarni SK (1997c) Neurosteroid coadministration prevents development of tolerance and augments recovery from benzodiazepine withdrawal anxiety and hyperactivity in mice. Meth Find Exp Clin Pharmacol 19:395-405
    • (1997) Meth Find Exp Clin Pharmacol , vol.19 , pp. 395-405
    • Reddy, D.S.1    Kulkarni, S.K.2
  • 49
    • 0031881890 scopus 로고    scopus 로고
    • Neuroprotective effects of neurosteroids against hypoxic stress-induced neurotoxicity in naive and FG 7142- Treated mice
    • Reddy DS, Kulkarni SK (1998a) Neuroprotective effects of neurosteroids against hypoxic stress-induced neurotoxicity in naive and FG 7142-treated mice. Ind J Pharmacol 30:6-15
    • (1998) Ind J Pharmacol , vol.30 , pp. 6-15
    • Reddy, D.S.1    Kulkarni, S.K.2
  • 50
    • 0345129948 scopus 로고    scopus 로고
    • Reversal of benzodiazepine inverse agonist FG 7142-induced anxiety syndrome by neurosteroids in mice
    • in press
    • Reddy DS, Kulkarni SK (1998b) Reversal of benzodiazepine inverse agonist FG 7142-induced anxiety syndrome by neurosteroids in mice. Meth Find Exp Clin Pharmacol 20 (in press)
    • (1998) Meth Find Exp Clin Pharmacol , vol.20
    • Reddy, D.S.1    Kulkarni, S.K.2
  • 52
    • 0026806389 scopus 로고
    • 2-Aryl-3-indoleacetamides (FGIN-1): A new class of potent and specific ligands for the mitochondrial DBI receptor (MDR)
    • Romeo E, Auta J, Kozikowski A, Ma D, Papadopoulos V, Puia G, Guidotti A (1992) 2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR). J Pharmacol Exp Ther 262:971-978
    • (1992) J Pharmacol Exp Ther , vol.262 , pp. 971-978
    • Romeo, E.1    Auta, J.2    Kozikowski, A.3    Ma, D.4    Papadopoulos, V.5    Puia, G.6    Guidotti, A.7
  • 53
    • 0030036766 scopus 로고    scopus 로고
    • Development and regeneration of the nervous system: A role for neurosteroids
    • Schumacher M, Robel P, Baulieu E-E (1996) Development and regeneration of the nervous system: a role for neurosteroids. Dev Neurosci 18:16-21
    • (1996) Dev Neurosci , vol.18 , pp. 16-21
    • Schumacher, M.1    Robel, P.2    Baulieu, E.-E.3
  • 54
    • 0023271933 scopus 로고
    • Progesterone alters GABa and glutamate responsiveness: A possible mechanism for its anxiolytic action
    • Smith SS, Waterhouse BD, Chapin JK, Woodward DJ (1987) Progesterone alters GABA and glutamate responsiveness: a possible mechanism for its anxiolytic action. Brain Res 400:759-766
    • (1987) Brain Res , vol.400 , pp. 759-766
    • Smith, S.S.1    Waterhouse, B.D.2    Chapin, J.K.3    Woodward, D.J.4
  • 55
    • 0025999108 scopus 로고
    • Neurosteroids pregnenolone and pregenolone-sulfate but not progesterone, block calcium currents in acutely isolated hippocampal CA1 neurons
    • Spencer KT, Plata-Salaman CR, Ffrench-Mullen JMH (1991) Neurosteroids pregnenolone and pregenolone-sulfate but not progesterone, block calcium currents in acutely isolated hippocampal CA1 neurons. Life Sci 49:235-239
    • (1991) Life Sci , vol.49 , pp. 235-239
    • Spencer, K.T.1    Plata-Salaman, C.R.2    Ffrench-Mullen, J.M.H.3
  • 56
    • 0025987983 scopus 로고
    • Auxiolytic activity of the progesterone metabolite 52-hydroxy-pregnan-32-01-20-one
    • Wieland S, Lan NC, Mirasedegi S, Gee KW (1991) Auxiolytic activity of the progesterone metabolite 52-hydroxy-pregnan-32-01-20-one. Brain Res 565:263-268
    • (1991) Brain Res , vol.565 , pp. 263-268
    • Wieland, S.1    Lan, N.C.2    Mirasedegi, S.3    Gee, K.W.4
  • 57
    • 0025329137 scopus 로고
    • Inverse modulation of γ-aminobutyric acid and glycine-induced currents by progesterone
    • Wu FS, Gibbs TT, Farb DH (1990) Inverse modulation of γ-aminobutyric acid and glycine-induced currents by progesterone. Mol Pharmacol 37:597-602
    • (1990) Mol Pharmacol , vol.37 , pp. 597-602
    • Wu, F.S.1    Gibbs, T.T.2    Farb, D.H.3
  • 58
    • 0025995802 scopus 로고
    • Pregnenolone sulfate: A positive allosteric modulator at the N-methyl-D-aspartate receptor
    • Wu FS, Gibbs TT, Farb DH (1991) Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor. Mol Pharmacol 40:333-336
    • (1991) Mol Pharmacol , vol.40 , pp. 333-336
    • Wu, F.S.1    Gibbs, T.T.2    Farb, D.H.3


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