Ro 15-4513 antagonizes alcohol-induced sedation in mice through αβγ2-type GABA A receptors

Frontiers in Neuroscience

Volumn , Issue 1 JAN, 2011, Pages

  Linden, Anni Maija ^a   Schmitt, Ulrich ^b   Leppä, Elli ^a   Wulff, Peer ^c   Wisden, William ^d   Lüddens, Hartmut ^b   Korpi, Esa R ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Alcohol antagonist; Ethanol; GABA a receptor; Inverse agonist; Ro 15 4513

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA; 4 AMINOBUTYRIC ACID A RECEPTOR BETA; 4 AMINOBUTYRIC ACID A RECEPTOR DELTA; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; 8 AZIDO 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO[1,5 A][1,4]BENZODIAZEPINE 3 CARBOXYLIC ACID ETHYL ESTER; ALCOHOL; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BRAIN REGION; CAUDATE NUCLEUS; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; DRUG RECEPTOR BINDING; FEMALE; KNOCKOUT MOUSE; MALE; MAZE TEST; MOUSE; MOUSE STRAIN; NONHUMAN; OPEN FIELD BEHAVIOR; PUTAMEN; SEDATION; SEPTUM PELLUCIDUM; TRANQUILIZING ACTIVITY; WILD TYPE;

EID: 79961168706     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2011.00003     Document Type: Article

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