What can in vitro models of COPD tell us?

Pulmonary Pharmacology and Therapeutics

Volumn 24, Issue 5, 2011, Pages 471-477

  Krimmer, D I ^a,b   Oliver, B G G ^a,b,c  

^a WOOLCOCK INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c CRC for Asthma and Airways   (Australia)

Author keywords

Airway remodelling; Airway smooth muscle; Chronic obstructive pulmonary disease; Cigarette smoke extract; Emphysema; Epithelial cell; Exacerbation; Fibroblast; Inflammation; Pharmacotheraoy

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLCYSTEINE; ATORVASTATIN; BAICALIN; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CARBOCISTEINE; CIGARETTE SMOKE; CORTICOSTEROID; DEXAMETHASONE; FLUINDOSTATIN; FLUTICASONE PROPIONATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ILOPROST; INTERLEUKIN 10; MATRIX METALLOPROTEINASE; MUSCARINIC RECEPTOR BLOCKING AGENT; NIFLUMIC ACID; PHOSPHODIESTERASE IV INHIBITOR; RESVERATROL; ROFLUMILAST; SALMETEROL; SIMVASTATIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TIOTROPIUM BROMIDE; TRANSFORMING GROWTH FACTOR BETA1;

AIRWAY REMODELING; APOPTOSIS; ARTICLE; BIOMASS; BREATHING MUSCLE; CELL CULTURE; CELL IMMORTALIZATION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CHRONIC BRONCHITIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPETITIVE INHIBITION; CORTICOSTEROID THERAPY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE EXACERBATION; DISEASE PREDISPOSITION; DRUG EFFICACY; DRUG INDICATION; DRUG MECHANISM; EPITHELIUM CELL; EX VIVO STUDY; EXPERIMENTAL MODEL; EXTRACELLULAR MATRIX; HUMAN; IN VITRO STUDY; LUNG ALVEOLUS CELL; LUNG EMPHYSEMA; LUNG PARENCHYMA; LUNG SEQUESTRATION; MACROPHAGE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; TISSUE CULTURE; UPREGULATION;

AIRWAY REMODELING; ANIMALS; CELLS, CULTURED; HUMANS; LUNG; MODELS, BIOLOGICAL; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING;

EID: 80052402572     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2010.12.002     Document Type: Article

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