Retinoic acid inhibits elastase-induced injury in human lung epithelial cell lines

American Journal of Respiratory Cell and Molecular Biology

Volumn 28, Issue 3, 2003, Pages 296-304

  Nakajoh, Mizue ^b   Fukushima, Takeyasu ^b   Suzuki, Tomoko ^b   Yamaya, Mutsuo ^b   Nakayama, Katsutoshi ^b   Sekizawa, Kiyohisa ^b   Sasaki, Hidetada ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOTIN; CASPASE 3; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; ELASTASE; RETINOIC ACID;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; EMPHYSEMA; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; NICK END LABELING; SPUTUM;

APOPTOSIS; CASPASE 3; CASPASES; CELL LINE, TRANSFORMED; CELL SURVIVAL; CELLS, CULTURED; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; HUMANS; KINETICS; LUNG; PANCREATIC ELASTASE; TRETINOIN;

EID: 0037370763     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.4845     Document Type: Article

References (40)

1. Celli, B. R., G. L. Snider, J. Heffner, B. Tiep, I. Ziment, B. Make, S. Braman, G. Olsen, and Y. Phillips. 1995. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 152:S77-S120.
2. Thom, T. J. 1989. International comparisons in COPD mortality. Am. Rev. Respir. Dis. 140:S27-S34.
3. Janoff, A. 1985. Elastases and emphysema: current assessment of the protease-antiprotease hypothesis. Am. Rev. Respir. Dis. 132:417-433.
4. Snider, G. L. 1992. Emphysema: the first two centuries-and beyond: a historical overview, with suggestions for future research. Part 2. Am. Rev. Respir. Dis. 146:1615-1622.
5. Hoidal, J. R., and D. E. Niewoehner. 1983. Pathogenesis of emphysema. Chest 83:679-685.
6. Garver, R. I., Jr., J.-F. Mornex, T. Nukiwa, M. Brantly, M. Courtney, J.-P. LeCoco, and R. G. Crystal. 1986. Alpha 1-antitrypsin deficiency and emphysema caused by homozygous inheritance of non-expressing alpha 1-antitrypsin genes. N. Engl. J. Med. 314:762-766.
7. Farber, J. L. 1994. Mechanisms of cell injury by activated oxygen species. Environ. Health Perspect. 102:17-24.
8. Ogushi, F., R. C. Hubbard, C. Vogelmeier, G. A. Fells, and R. G. Crystal. 1991. Risk factors for emphysema: cigarette smoking is associated with a reduction in the association rate constant of lung α1-antitrypsin for neutrophil elastase. J. Clin. Invest. 87:1060-1065.
9. Hayes, J. A., A. Korthy, and G. L. Snider. 1975. Pathology of elastase-induced panacinar emphysema in hamsters. J. Pathol. 117:1-14.
10. Kaplan, P. D., C. Kuhn, and J. A. Pierce. 1973. The induction of emphysema with elastase: I. The evolution of the lesion and the influence of serum. J. Lab. Clin. Med. 82:349-356.
11. Christensen, T. G., A. L. Korthy, G. L. Snider, and J. A. Hayes. 1977. Irreversible bronchial goblet cell metaplasia in hamsters with elastase-induced panacinar emphysema. J. Clin. Invest. 59:397-404.
12. Furuno, T., T. Mitsuyama, K. Hidaka, T. Tanaka, and N. Hara. 1997. The role of neutrophil elastase in human pulmonary artery endothelial cell injury. Int. Arch. Allergy Immunol 112:262-269.
13. Venaille, T. J., G. Ryan, and B. W. Robinson. 1998. Epithelial cell damage is induced by neutrophil-derived, not pseudomonas-derived, proteases in cystic fibrosis sputum. Respir. Med. 92:233-240.
14. Kasahara, Y., R. M. Tuder, L. Taraseviciene-Stewart, T. D. Le Cras, S. Abman, P. K. Hirth, J. Waltenberger, and N. F. Voelkel. 2000. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J. Clin. Invest. 106:1311-1319.
15. Massaro, G. D., and D. Massaro. 1997. Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats. Nat. Med. 3:675-677.
16. Grummer, M. A., and R. D. Zachman. 1995. Postnatal rat lung retinoic acid receptor (RAR) mRNA expression and effects of dexamethasone on RAR-β mRNA. Pediatr. Pulmonol. 20:234-240.
17. Jetten, A. M., A. R. Brody, M. A. Deas, G. E. R. Hook, J. I. Rearick, and S. M. Thacher. 1987. Retinoic acid and substratum regulate the differentiation of rabbit tracheal epithelial cells into squamous and secretory phenotype: morphological and biochemical characterization. Lab. Invest. 56:654-664.
18. Lechner, J. F., A. Haugen, I. A. McClendon, and E. W. Pettis. 1982. Clonal growth of normal adult human bronchial epithelial cells in a serum-free medium. In Vitro 18:633-642.
19. Ong, D. E., and F. Chytil. 1976. Changes in levels of cellular retinol- and retinoic acid-binding protein of liver and lung during perinatal development of rat. Proc. Natl. Acad. Sci. USA 73:3976-3978.
20. James, S. Y., M. A. Williams, A. C. Newland, and K. W. Colston. 1999. Leukemia cell differentiation: cellular and molecular interactions of retinoids and vitamin D. Gen. Pharmacol. 32:143-154.
21. Yang, J. J., R. Kettritz, R. J. Falk, J. C. Jennette, and M. L. Gaido. 1996. Apoptosis of endothelial cells induced by the neutrophil serine protease 3 and elastase. Am. J. Pathol. 149:1617-1626.
22. Moreno-Manzano, V., Y. Ishikawa, J. Lucio-Cazana, and M. Kitamura. 1999. Supression of apoptosis by all-trans-retinoic acid: dual intervention in the c-Jun n-terminal kinase-AP-1 pathway. J. Biol. Chem. 274:20251-20258.
23. Yamaya, M., W. E. Finkbeiner, S. Y. Chun, and J. H. Widdicombe. 1992. Differentiated structure and function of cultures from human tracheal epithelium. Am. J. Physiol. 262:L713-L724.
24. Mosmann, T. 1983. Rapid colorimetric assay for cell growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55-63.
25. Fortenberry, J. D., M. L. Owens, and L. A. S. Brown. 1997. S-nitrosoglutathione enhances neutrophil DNA fragmentation and cell death. Am. J. Physiol. 276:L435-L442.
26. Gavrieli, Y., Y. Sherman, and S. A. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific lebeling of nuclear DNA fragmentation. J. Cell Biol. 119:493-501.
27. Fernandes-Alnemri, T., G. Litwack, and E. S. Alnemri. 1994. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-converting enzyme. J. Biol. Chem. 269:30761-30764.
28. Fujimoto, K., M. Ogawa, N. Saito, G. Kosaki, N. Minamura, and T. Yamamoto. 1980. A novel method of isolation and some characteristic properties of human pancreatic elastases. Biochim. Biophys. Acta. 612:262-267.
29. Nicholson, D. W., A. Ali, N. A. Thornberry, J. P. Vallancourt, C. K. Ding, M. Gallant, Y. Gareau, P. R. Griffin, M. Labelle, and Y. A. Lazebnik. 1995. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376:37-43.
30. Karlinsky, J. B., and G. L. Snider. 1978. Animal models of emphysema. Am. Rev. Respir. Dis. 117:1109-1133.
31. Kuhn, C., S. Yu, M. Chraplyvy, H. Linder, and R. M. Senior. 1976. The induction of emphysema with elastase: II. Changes in connective tissue. Lab. Invest. 34:372-380.
32. Nahori, M. A., P. Renesto, B. B. Vargaftig, and M. Chignard. 1992. Activation and damage of cultured airway epithelial cells by human elastase and cathepsin G. Eur. J. Pharmacol. 228:213-218.
33. Bardales, R. H., S. S. Xie, R. F. Schaefer, and S. M. Hsu. 1996. Apoptosis is a major pathway responsible for the resolution of type II pneumocytes in acute lung injury. Am. J. Pathol. 149:845-852.
34. Tewari, M., L. T. Quan, K. O'Rourke, S. Desnoyers, Z. Zeng, D. R. Beidler, G. G. Poirier, G. S. Salvesen, and V. M. Dixit. 1995. Yama/CPP32β, a mammalian homolog of CED-3, is a Crm-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase. Cell 81:801-808.
35. Torriglia, A., C. Negri, E. Chaudun, E. Prosperi, Y. Courtois, M. F. Counis, and A. I. Scovassi. 1999. Differential involvement of Dnases in HeLa cell apoptosis induced by etoposide and long term-culture. Cell Death Differ. 6:234-244.
36. Zakeri, Z. F., and H. S. Ahuja. 1997. Cell death/apoptosis: normal, chemically induced, and teratogenic effect. Mutat. Res. 396:149-161.
37. Kim, H. S., D. B. Hausman, M. M. Compton, R. G. Dean, R. J. Martin, G. J. Hausman, and D. L. Hartzell. 2000. Induction of apoptosis by all-trans-retinoic acid and C2-ceramide treatment in rat stromal-vascular cultures. Biochem. Biophys. Res. Commun. 270:76-80.
38. Taddeo, B., B. J. Nickoloff, and K. E. Foreman. 2000. Caspase inhibitor blocks human immunodeficiency virus 1-induced T-cell death without enhancement of HIV-1 replication and dimethyl sulfoxide increases HIV-1 replication without influencing T-cell survival. Arch. Pathol. Lab. Med. 124:240-245.
39. Sklan, D., P. Rappaport, and M. Vered. 1990. Inhibition of the activity of human leukocyte elastase by lipids particularly oleic acid and retinoic acid. Lung 168:323-332.
40. Trevani, A. S., G. Andonegui, M. Giordano, M. Nociari, P. Fontan, G. Dran, and J. R. Geffner. 1996. Neutrophil apoptosis induced by proteolytic enzymes. Lab. Invest. 74:711-721.