Statins inhibit matrix metalloproteinase release from human lung fibroblasts

European Respiratory Journal

Volumn 35, Issue 3, 2010, Pages 637-646

  Kamio, K ^a   Liu, X D ^a   Sugiura, H ^b   Togo, S ^a   Kawasaki, S ^a   Wang, X ^a   Ahn, Y ^a   Hogaboam, C ^c   Rennard, S I ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Collagen; Degradation; Fibroblasts; Matrix metalloproteinases; Statins

Indexed keywords

ATORVASTATIN; FARNESYL DIPHOSPHATE; GELATINASE B; GERANYLGERANYL PYROPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYDROXYPROLINE; INTERLEUKIN 1ALPHA; INTERSTITIAL COLLAGENASE; LEUKOCYTE ELASTASE; MATRIX METALLOPROTEINASE; MESSENGER RNA; MEVALONIC ACID; SIMVASTATIN; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; COLLAGEN DEGRADATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; LUNG FIBROBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CELLS, CULTURED; FIBROBLASTS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MATRIX METALLOPROTEINASES; PULMONARY ALVEOLI; RNA, MESSENGER;

EID: 77951152110     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00134707     Document Type: Article

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