Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 297, Issue 1, 2009, Pages

  Van Der Toorn, Marco ^a   Rezayat, Delaram ^a   Kauffman, Henk F ^a   Bakker, Stephan J L ^a   Gans, Rijk O B ^a   Koëter, Gerard H ^a   Choi, Augustine M K ^b   Van Oosterhout, Antoon J M ^a   Slebos, Dirk Jan ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Chronic obstructive pulmonary disease; Epithelial cells; Mitochondria; Reactive oxygen species

Indexed keywords

ADENOSINE TRIPHOSPHATE; CIGARETTE SMOKE; CYSTEINE; DICHLOROFLUORESCEIN; HEXANE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; THIOL GROUP;

ARTICLE; BRONCHUS MUCOSA; CELL ACTIVITY; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; LIPOPHILICITY; LUNG ALVEOLUS EPITHELIUM; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL;

CELL LINE; EPITHELIAL CELLS; FILTRATION; GASES; HUMANS; LIPIDS; LUNG; MITOCHONDRIA; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; SMOKE; SOLUBILITY; SOLUTIONS; SULFHYDRYL COMPOUNDS; TOBACCO; WATER;

EID: 67650074827     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.90461.2008     Document Type: Article

References (40)

1. Afri M, Gottlieb HE, Frimer AA. Superoxide organic chemistry within the liposomal bilayer, part II: a correlation between location and chemistry. Free Radic Biol Med 32: 605-618, 2002.
2. Barnes PJ, Shapiro SD, Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J 22: 672-688, 2003.
3. Bonvallot V, Baeza-Squiban A, Baulig A, Brulant S, Boland S, Muzeau F, Barouki R, Marano F. Organic compounds from diesel exhaust particles elicit a proinflammatory response in human airway epithelial cells and induce cytochrome p450 1A1 expression. Am J Respir Cell Mol Biol 25: 515-521, 2001.
4. Bowler RP, Barnes PJ, Crapo JD. The role of oxidative stress in chronic obstructive pulmonary disease. COPD 1: 255-277, 2004.
5. Brunnemann KD, Hoffmann D. Analytical studies on tobacco-specific N-nitrosamines in tobacco and tobacco smoke. Crit Rev Toxicol 21: 235-240, 1991.
6. Brzezinska AK, Lohr N, Chilian WM. Electrophysiological effects of O2*- on the plasma membrane in vascular endothelial cells. Am J Physiol Heart Circ Physiol 289: H2379-H2386, 2005.
7. Calikoglu M, Unlu A, Tamer L, Ercan B, Bugdayci R, Atik U. The levels of serum vitamin C, malonyldialdehyde and erythrocyte reduced glutathione in chronic obstructive pulmonary disease and in healthy smokers. Clin Chem Lab Med 40: 1028-1031, 2002.
8. Chandel NS, Schumacker PT. Cells depleted of mitochondrial DNA (rho0) yield insight into physiological mechanisms. FEBS Lett 454: 173-176, 1999.
9. Chen Y, Millan-Ward E, Kong J, Israels SJ, Gibson SB. Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. J Cell Sci 120: 4155-4166, 2007.
10. Chen Z, Boreham J. Smoking and cardiovascular disease. Semin Vasc Med 2: 243-252, 2002.
11. Gosker HR, Wouters EF, van der Vusse GJ, Schols AM. Skeletal muscle dysfunction in chronic obstructive pulmonary disease and chronic heart failure: underlying mechanisms and therapy perspectives. Am J Clin Nutr 71: 1033-1047, 2000.
12. Gosker HR, Zeegers MP, Wouters EF, Schols AM. Muscle fibre type shifting in the vastus lateralis of patients with COPD is associated with disease severity: a systematic review and meta-analysis. Thorax 62: 944-949, 2007.
13. Hoshino Y, Mio T, Nagai S, Miki H, Ito I, Izumi T. Cytotoxic effects of cigarette smoke extract on an alveolar type II cell-derived cell line. Am J Physiol Lung Cell Mol Physiol 281: L509-L516, 2001.
14. Kelsen SG, Duan X, Ji R, Perez O, Liu C, Merali S. Cigarette smoke induces an unfolded protein response in the human lung: a proteomic approach. Am J Respir Cell Mol Biol 38: 541-550, 2008.
15. 2-.-mediated mitochondrial outgrowth. Am J Physiol Cell Physiol 288: C1440-C1450, 2005.
16. Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environ Health Perspect 111: 455-460, 2003.
17. Liu J, Killilea DW, Ames BN. Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-α-lipoic acid. Proc Natl Acad Sci USA 99: 1876-1881, 2002.
18. Lu X, Cai J, Kong H, Wu M, Hua R, Zhao M, Liu J, Xu G. Analysis of cigarette smoke condensates by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry I acidic fraction. Anal Chem 75: 4441-4451, 2003.
19. Mao GD, Poznansky MJ. Electron spin resonance study on the permeability of superoxide radicals in lipid bilayers and biological membranes. FEBS Lett 305: 233-236, 1992.
20. Miro O, Alonso JR, Jarreta D, Casademont J, Urbano-Marquez A, Cardellach F. Smoking disturbs mitochondrial respiratory chain function and enhances lipid peroxidation on human circulating lymphocytes. Carcinogenesis 20: 1331-1336, 1999.
21. Nohl H, Gille L, Kozlov A, Staniek K. Are mitochondria a spontaneous and permanent source of reactive oxygen species? Redox Rep 8: 135-141, 2003.
22. Orth SR, Ritz E, Schrier RW. The renal risks of smoking. Kidney Int 51: 1669-1677, 1997.
23. Oudijk EJ, Lammers JW, Koenderman L. Systemic inflammation in chronic obstructive pulmonary disease. Eur Respir J, Suppl 46: 5s-13s, 2003.
24. Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med 163: 1256-1276, 2001.
25. Pieczenik SR, Neustadt J. Mitochondrial dysfunction and molecular pathways of disease. Exp Mol Pathol 83: 84-92, 2007.
26. Prokopczyk B, Hoffmann D, Bologna M, Cunningham AJ, Trushin N, Akerkar S, Boyiri T, Amin S, Desai D, Colosimo S, Pittman B, Leder G, Ramadani M, Henne-Bruns D, Beger HG, El-Bayoumy K. Identification of tobacco-derived compounds in human pancreatic juice. Chem Res Toxicol 15: 677-685, 2002.
27. Rabinovich RA, Bastos R, Ardite E, Llinas L, Orozco-Levi M, Gea J, Vilaro J, Barbera JA, Rodriguez-Roisin R, Fernandez-Checa JC, Roca J. Mitochondrial dysfunction in COPD patients with low body mass index. Eur Respir J 29: 643-650, 2007.
28. Rahman I. The role of oxidative stress in the pathogenesis of COPD: implications for therapy. Treat Respir Med 4: 175-200, 2005.
29. Rahman I, MacNee W. Role of oxidants/antioxidants in smoking-induced lung diseases. Free Radic Biol Med 21: 669-681, 1996.
30. Remels AH, Gosker HR, van der Velden J, Langen RC, Schols AM. Systemic inflammation and skeletal muscle dysfunction in chronic obstructive pulmonary disease: state of the art and novel insights in regulation of muscle plasticity. Clin Chest Med 28: 537-552, vi, 2007.
31. Rustemeier K, Stabbert R, Haussmann HJ, Roemer E, Carmines EL. Evaluation of the potential effects of ingredients added to cigarettes. Part 2: chemical composition of mainstream smoke. Food Chem Toxicol 40: 93-104, 2002.
32. Slebos DJ, Ryter SW, van der Toorn M, Liu F, Guo F, Baty CJ, Karlsson JM, Watkins SC, Kim HP, Wang X, Lee JS, Postma DS, Kauffman HF, Choi AM. Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death. Am J Respir Cell Mol Biol 36: 409-417, 2007.
33. 2 challenge. Eur Respir J 29: 633-642, 2007.
34. Smith CJ, Fischer TH. Particulate and vapor phase constituents of cigarette mainstream smoke and risk of myocardial infarction. Atherosclerosis 158: 257-267, 2001.
35. Tkacova R, Kluchova Z, Joppa P, Petrasova D, Molcanyiova A. Systemic inflammation and systemic oxidative stress in patients with acute exacerbations of COPD. Respir Med 101: 1670-1676, 2007.
36. Tsuchiya M, Asada A, Kasahara E, Sato EF, Shindo M, Inoue M. Smoking a single cigarette rapidly reduces combined concentrations of nitrate and nitrite and concentrations of antioxidants in plasma. Circulation 105: 1155-1157, 2002.
37. van der Toorn M, Slebos DJ, de Bruin HG, Leuvenink HG, Bakker SJ, Gans RO, Koeter GH, van Oosterhout AJ, Kauffman HF. Cigarette smoke induced blockade of the mitochondrial respiratory chain switches lung epithelial cell apoptosis into necrosis. Am J Physiol Lung Cell Mol Physiol 292: L1211-L1218, 2007.
38. van der Toorn M, Smit-de Vries MP, Slebos DJ, de Bruin HG, Abello N, van Oosterhout AJ, Bischoff R, Kauffman HF. Cigarette smoke irreversibly modifies glutathione in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 293: L1156-L1162, 2007.
39. van Klaveren RJ, Roelant C, Boogaerts M, Demedts M, Nemery B. Involvement of an NAD(P)H oxidase-like enzyme in superoxide anion and hydrogen peroxide generation by rat type II cells. Thorax 52: 465-471, 1997.
40. Wright DT, Cohn LA, Li H, Fischer B, Li CM, Adler KB. Interactions of oxygen radicals with airway epithelium. Environ Health Perspect 102, Suppl 10: 85-90, 1994.