Modulation of matrix metalloproteinase production from human lung fibroblasts by type 4 phosphodiesterase inhibitors

Life Sciences

Volumn 75, Issue 7, 2004, Pages 823-840

  Martin Chouly, Corinne A E ^a   Astier, Alexandra ^a   Jacob, Claire ^a,b   Pruniaux, Marie Pierre ^b   Bertrand, Claude ^b   Lagente, Vincent ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

^b PFIZER INC   (United States)

Author keywords

Human lung fibroblasts; Metalloproteinases; PDE4 inhibitors

Indexed keywords

AMIDE; CI 1044; CILOMILAST; DEXAMETHASONE; ESTERASE INHIBITOR; GELATINASE A; MATRIX METALLOPROTEINASE; N (9 AMINO 3,4,6,7 TETRAHYDRO 4 OXO 1 PHENYLPYRROLO[3,2,2 J,K][1,4]BENZODIAZEPIN 3 YL) 3 PYRIDINECARBOXAMIDE; ROLIPRAM; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EVALUATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LUNG FIBROBLAST; PROTEIN SYNTHESIS; ZYMOGRAPHY;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; AZEPINES; BLOTTING, WESTERN; BRONCHODILATOR AGENTS; CARBOXYLIC ACIDS; CELL LINE; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; FIBROBLASTS; HUMANS; ISOENZYMES; LUNG; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 2; METALLOPROTEASES; NIACINAMIDE; NITRILES; PHOSPHODIESTERASE INHIBITORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; ROLIPRAM; TETRADECANOYLPHORBOL ACETATE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 2942618507     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.01.021     Document Type: Article

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