PfMDR1: Mechanisms of transport modulation by functional polymorphisms

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Ferreira, Pedro Eduardo ^a,b   Holmgren, Gabrielle ^a   Veiga, Maria Isabel ^a,b   Uhlén, Per ^a   Kaneko, Akira ^a   Gil, José Pedro ^a,b,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF ALGARVE   (Portugal)

^c BINGHAMTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; CHLOROQUINE; DEETHYLAMODIAQUINE; MSBA PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; ANTIMALARIAL AGENT; GLYCOPROTEIN P; PROTOZOAL PROTEIN;

AMINO ACID COMPOSITION; ANTIMALARIAL ACTIVITY; ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; CELL VACUOLE; COMPUTER MODEL; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG BINDING SITE; GENE FUNCTION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; LIPOPHILICITY; MOLECULAR COMPUTER; MOLECULAR DOCKING; NONHUMAN; PLASMODIUM FALCIPARUM; PROCESS DEVELOPMENT; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; DRUG RESISTANCE; GENETICS; HUMAN; METABOLISM; PROTEIN CONFORMATION; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSPORT AT THE CELLULAR LEVEL;

BACTERIA (MICROORGANISMS);

ANTIMALARIALS; BINDING SITES; BIOLOGICAL TRANSPORT; DRUG RESISTANCE; HUMANS; MODELS, MOLECULAR; P-GLYCOPROTEIN; PLASMODIUM FALCIPARUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN CONFORMATION; PROTOZOAN PROTEINS;

EID: 80052362737     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023875     Document Type: Article

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