Minor groove to major groove, an unusual DNA sequence-dependent change in bend directionality by a distamycin dimer

Biochemistry

Volumn 50, Issue 35, 2011, Pages 7674-7683

  Wang, Shuo ^a   Munde, Manoj ^a   Wang, Siming ^a   Wilson, W David ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASE PAIRS; BENDING DIRECTIONS; BINDING AFFINITIES; CONFORMATIONAL CHANGE; COOPERATIVITY; DIFFERENT SIZES; DISTAMYCIN; IN-PHASE; MINOR GROOVES; NETROPSIN; POLYACRYLAMIDE GEL ELECTROPHORESIS; SEQUENCE-DEPENDENT; STRUCTURAL EFFECT; THERAPEUTIC EFFECTS;

BINDING ENERGY; BINDING SITES; CONFORMATIONS; DIMERS; DNA; ELECTROPHORESIS; MASS SPECTROMETRY; STOICHIOMETRY; SURFACE PLASMON RESONANCE;

DNA SEQUENCES;

CONGOCIDINE; DIMER; DISTAMYCIN A; MONOMER; SINGLE STRANDED DNA;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; DNA SEQUENCE; DRUG BINDING; ELECTROSPRAY MASS SPECTROMETRY; EQUILIBRIUM CONSTANT; MASS SPECTROMETRY; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STEADY STATE; STOICHIOMETRY; STRUCTURE ANALYSIS; SURFACE PLASMON RESONANCE;

BASE SEQUENCE; DISTAMYCINS; DNA-BINDING PROTEINS; NUCLEIC ACID HETERODUPLEXES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION;

EID: 80052227453     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201010g     Document Type: Article

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