Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 9, 2011, Pages 4096-4102

  Akshay, Subramanian ^a   Bertea, Mihai ^a   Hobbie, Sven N ^a,b   Oettinghaus, Björn ^a,c   Shcherbakov, Dimitri ^a   Boẗtger, Erik C ^a   Akbergenov, Rashid ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b SINGAPORE MIT ALLIANCE FOR RESEARCH AND TECHNOLOGY   (Singapore)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL RNA; KETOLIDE; MACROLIDE; PEPTIDYLTRANSFERASE; RIBOSOME RNA; RNA 16S; RNA 23S;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL MUTATION; BINDING SITE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING; GENETIC VARIABILITY; MINIMUM INHIBITORY CONCENTRATION; MUTAGENESIS; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PHENOTYPE; PHYLOGENY; PRIORITY JOURNAL; PROPIONIBACTERIUM; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; PROTEIN SYNTHESIS; PROTEOBACTERIA; RIBOSOME; RNA SEQUENCE; SPECIES DIFFERENCE;

AMINOGLYCOSIDES; BINDING SITES; ERYTHROMYCIN; KETOLIDES; MACROLIDES; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM SMEGMATIS; PHYLOGENY; RNA, RIBOSOMAL; RNA, RIBOSOMAL, 16S; RNA, RIBOSOMAL, 23S;

EID: 80051821485     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01398-10     Document Type: Article

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