Sequence and level of endogenous expression of calcium channel β subunits in Schistosoma mansoni displaying different susceptibilities to praziquantel

Molecular and Biochemical Parasitology

Volumn 130, Issue 2, 2003, Pages 111-115

  Valle, Cristiana ^a   Troiani, Anna Rita ^a   Festucci, Alfredo ^a   Pica Mattoccia, Livia ^a   Liberti, Piero ^a   Wolstenholme, Adrian ^b   Francklow, Katherine ^c   Doenhoff, Michael J ^c   Cioli, Donato ^a  

^a CNR   (Italy)

^b University of Bath   (United Kingdom)

^c BANGOR UNIVERSITY   (United Kingdom)

Author keywords

Calcium channels; Drug resistance; Praziquantel; Schistosoma mansoni

Indexed keywords

CALCIUM; CALCIUM CHANNEL; COMPLEMENTARY DNA; PRAZIQUANTEL; PROTEIN SUBUNIT;

ARTICLE; BETA CHAIN; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DNA SEQUENCE; DRUG MECHANISM; DRUG RESISTANCE; DRUG SENSITIVITY; IMMATURITY; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PARASITE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SCHISTOSOMA MANSONI; WORM;

SCHISTOSOMA; SCHISTOSOMA MANSONI;

EID: 0142043482     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(03)00171-3     Document Type: Article

References (17)

1. WHO Expert Committee. Prevention and control of schistosomiasis and soil-transmitted helminthiasis. Geneva; 2002.
2. Gryseels B., Mbaye A., De Vlas S.et al. Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence. Trop Med. Intl. Hlth. 6:2002;864-873.
3. Gonnert R., Andrews P. Praziquantel, a new broad spectrum antischistosomal agent. Z Parasitenk. 52:1977;129-150.
4. Sabah A.A., Fletcher C., Webbe G., Doenhoff M.J. Schistosoma mansoni - chemotherapy of infections of different ages. Exp. Parasitol. 61:1986;294-303.
5. Piquet M., Vercruysse J., Shaw D.J., Diop M., Ly A. Efficacy of praziquantel against Schistosoma mansoni in northern Senegal. Trans. R. Soc. Trop. Med. Hyg. 92:1998;90-93.
6. Ismail M., Metwally A., Farghaly A., Bruce J., Tao L.-F., Bennett J.L. Characterization of isolates of Schistosoma mansoni from Egyptian villagers that tolerate high doses of praziquantel. Am. J. Trop. Med. Hyg. 55:1996;214-218.
7. Ismail M., Botros S., Metwally A.et al. Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers. Am. J. Trop. Med. Hyg. 60:1999;932-935.
8. Fallon P.G., Sturrock R.F., Niang C.M., Doenhoff M.J. Diminished susceptibility to praziquantel in a Senegal isolate of Schistosoma mansoni. Am. J. Trop. Med. Hyg. 53:1995;61-62.
9. Liang Y.-S., Coles G.C., Dai J.-R., Zhu Y.-C., Doenhoff M.J. Biological characteristics of praziquantel-resistant and -susceptible isolates of Schistosoma mansoni. Ann. Trop. Med. Parasitol. 95:2001;715-723.
10. William S., Sabra A., Ramzy F.et al. Stability and reproductive fitness of Schistosoma mansoni isolates with decreased sensitivity to praziquantel. Intl. J. Parasitol. 31:2001;1093-1100.
11. Fallon P.G., Doenhoff M.J. Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug-specific. Am. J. Trop. Med. Hyg. 51:1994;83-88.
12. Kohn A.B., Anderson P.A.V., Roberts-Misterly J.M., Greenberg R.M. Schistosome calcium channel β subunits: unusual modulatory effects and potential role in the action of the antischistosomal drug praziquantel. J. Biol. Chem. 276:2001;36873-36876.
13. Pax R., Bennett J.L., Fetterer R. A benzodiazepine derivative and praziquantel: effects on musculature of Schistosoma mansoni and Schistosoma japonicum. Naunyn-Schiedberg's Arch. Pharmacol. 304:1978;309-315.
14. Su S., Bird R.C. Cell cycle differentiation and tissue-independent expression of ribosomal protein L37. Eur. J. Biochem. 232:1995;789-797.
15. 2+ on the bilayer-isotropic-hexagonal transition of model membranes. Mol. Biochem. Parasitol. 29:1988;55-60.
16. Schepers H., Brasseur R., Goormaghtigh E., Duquenoy P., Ruysschaert J.M. Mode of insertion of praziquantel and derivatives into lipid membranes. Biochem. Pharmacol. 37:1988;1615-1623.
17. McTigue M.A., Williams D.R., Tainer J.A. Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel. J. Mol. Biol. 246:1995;21-27.