The use of trehalose in the preparation of specimens for molecular electron microscopy

Micron

Volumn 42, Issue 8, 2011, Pages 762-772

  Chiu, Po Lin ^a   Kelly, Deborah F ^b   Walz, Thomas ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b VIRGINIA TECH CARILION SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Electron crystallography; Negative staining; Single particle EM; Specimen preparation; Sugar embedding

Indexed keywords

2-D CRYSTALS; BIOLOGICAL SPECIMENS; ELECTRON CRYSTALLOGRAPHY; MACROMOLECULAR COMPLEXES; NATIVE STRUCTURES; NEGATIVE STAINING; PROTEIN CRYSTAL; SINGLE-PARTICLE; SPECIMEN PREPARATION METHOD; STRESS CONDITION; STRUCTURAL STUDIES;

CRYSTALLOGRAPHY; CRYSTALS; ELECTRONS; MINERALOGY; SUGARS;

SPECIMEN PREPARATION;

TREHALOSE;

CRYSTALLOGRAPHY; ELECTRON MICROSCOPY; LABORATORY DIAGNOSIS; METABOLISM; METHODOLOGY; REVIEW;

CRYSTALLOGRAPHY; MICROSCOPY, ELECTRON; SPECIMEN HANDLING; TREHALOSE;

EID: 80051591706     PISSN: 09684328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micron.2011.06.005     Document Type: Review

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