Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes

Toxicology

Volumn 288, Issue 1-3, 2011, Pages 8-17

  Bjork, J A ^a   Butenhoff, J L ^b   Wallace, K B ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b 3M COMPANY   (United States)

Author keywords

CAR; LXR; Metabolic regulation; Perfluoroalkyl acids; PPARA; PXR; Species specificity

Indexed keywords

CARBOHYDRATE; CELL NUCLEUS RECEPTOR; LIPID; PERFLUOROOCTANESULFONIC ACID; PERFLUOROOCTANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRIACYLGLYCEROL;

ARTICLE; BILE ACID SYNTHESIS; BIOLOGICAL ACTIVITY; CARBOHYDRATE METABOLISM; FATTY ACID OXIDATION; GLUCONEOGENESIS; HUMAN; KETOGENESIS; LIPID METABOLISM; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPECIES DIFFERENCE; TRANSACTIVATION; UREA CYCLE;

ALKANESULFONIC ACIDS; ANIMALS; CARBOHYDRATE METABOLISM; ENVIRONMENTAL POLLUTANTS; FATTY ACIDS; FLUOROCARBONS; HEPATOCYTES; HUMANS; OCTANOIC ACIDS; OXIDATION-REDUCTION; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECIES SPECIFICITY; TRIGLYCERIDES;

MUS; RATTUS; RODENTIA;

EID: 79961024699     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.06.012     Document Type: Article

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