Developmental toxicity of perfluorooctane sulfonate (PFOS) is not dependent on expression of peroxisome proliferator activated receptor-alpha (PPARα) in the mouse

Reproductive Toxicology

Volumn 27, Issue 3-4, 2009, Pages 258-265

  Abbott, Barbara D ^a   Wolf, Cynthia J ^a   Das, Kaberi P ^a   Zehr, Robert D ^a   Schmid, Judith E ^a   Lindstrom, Andrew B ^b   Strynar, Mark J ^b   Lau, Christopher ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Developmental toxicity; Perfluorooctane sulfonate (PFOS); Peroxisome proliferator activated receptor alpha (PPAR )

Indexed keywords

PERFLUOROOCTANESULFONIC ACID; PERFLUOROOCTANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIRTH WEIGHT; BLOOD LEVEL; BODY WEIGHT; EMBRYO; EMBRYOTOXICITY; KNOCKOUT MOUSE; LIVER WEIGHT; MOUSE; NEWBORN; NEWBORN MORTALITY; NONHUMAN; POSTNATAL DEVELOPMENT; PREGNANCY; PRENATAL EXPOSURE; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR UPREGULATION; WEIGHT GAIN;

ALKANESULFONIC ACIDS; ANIMALS; BIRTH WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; EYE; FEMALE; FLUOROCARBONS; LIVER; MALE; MATERNAL EXPOSURE; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; ORGAN SIZE; PPAR ALPHA; SEX FACTORS; SURVIVAL ANALYSIS;

MUS; RATTUS; RODENTIA;

EID: 64949176632     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2008.05.061     Document Type: Article

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