Biotransformation of N-Ethyl-N-(2-hydroxyethyl)perfluorooctanesulfonamide by rat liver microsomes, cytosol, and slices and by expressed rat and human cytochromes P450

Chemical Research in Toxicology

Volumn 17, Issue 6, 2004, Pages 767-775

  Xu, Lin ^a   Krenitsky, Daria M ^a   Seacat, Andrew M ^b   Butenhoff, John L ^b   Anders, M W ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b 3M COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 BENZYLIMIDAZOLE; ADHESIVE AGENT; AJMALICINE; ALLYL SULFIDE; CIMETIDINE; CLOTRIMAZOLE; CYTOCHROME P450 2C11; CYTOCHROME P450 2C19; CYTOCHROME P450 3A2; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; CYTOCHROME P450 INHIBITOR; CYTOCHROME P450 ISOENZYME; DIPHENHYDRAMINE; DIPHENYLIODONIUM SALT; DISULFIRAM; FURAFYLLINE; N ETHYL N (2 HYDROXYETHYL)PERFLUOROOCTANESULFONAMIDE; N ETHYLPERFLUOROOCTANESULFONAMIDOACETATE; OCTYLAMINE; ORPHENADRINE; PERFLUOROOCTANE; PERFLUOROOCTANESULFONAMIDE; PERFLUOROOCTANESULFONAMIDOACETATE; PERFLUOROOCTANESULFONIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SURFACTANT; TROLEANDOMYCIN; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCURONIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; DEALKYLATION; DEETHYLATION; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIVER CYTOSOL; LIVER MICROSOME; LIVER SLICE; MALE; MASS SPECTROMETRY; NONHUMAN; RAT;

ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; CYTOSOL; FLUOROCARBONS; HUMANS; LIVER; MALE; MASS SPECTROMETRY; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; SUBCELLULAR FRACTIONS; SULFONAMIDES;

ANIMALIA;

EID: 3042727192     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx034222x     Document Type: Article

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