-
1
-
-
0036154857
-
Control of mitochondrial β-oxidation flux
-
Eaton S 2002 Control of mitochondrial β-oxidation flux. Prog Lipid Res 41:197-239
-
(2002)
Prog Lipid Res
, vol.41
, pp. 197-239
-
-
Eaton, S.1
-
2
-
-
0034956080
-
Peroxisomal fatty acid α- and β-oxidation in humans: Enzymology, peroxisomal metabolite transporters and peroxisomal diseases
-
Wanders RJ, Vreken P, Ferdinandusse S, Jansen GA, Waterham HR, van Roermund CW, Van Grunsven EG 2001 Peroxisomal fatty acid α- and β-oxidation in humans: Enzymology, peroxisomal metabolite transporters and peroxisomal diseases. Biochem Soc Trans 29:250-267
-
(2001)
Biochem Soc Trans
, vol.29
, pp. 250-267
-
-
Wanders, R.J.1
Vreken, P.2
Ferdinandusse, S.3
Jansen, G.A.4
Waterham, H.R.5
Van Roermund, C.W.6
Van Grunsven, E.G.7
-
3
-
-
0034939632
-
Peroxisomal β-oxidation and peroxisome proliferator-activated receptor α: An adaptive metabolic system
-
Reddy JK, Hashimoto T 2001 Peroxisomal β-oxidation and peroxisome proliferator-activated receptor α: An adaptive metabolic system. Annu Rev Nutr 21:193-230
-
(2001)
Annu Rev Nutr
, vol.21
, pp. 193-230
-
-
Reddy, J.K.1
Hashimoto, T.2
-
4
-
-
6044233001
-
Role of fibric acid derivatives in the management of risk factors for coronary heart disease
-
Despres JP, Lemieux I, Robins SJ 2004 Role of fibric acid derivatives in the management of risk factors for coronary heart disease. Drugs 64:2177-2198
-
(2004)
Drugs
, vol.64
, pp. 2177-2198
-
-
Despres, J.P.1
Lemieux, I.2
Robins, S.J.3
-
5
-
-
0034669171
-
Role of LXRs in control of lipogenesis
-
Schultz JR, Tu H, Luk A, Repa JJ, Medina JC, Li L, Schwendner S, Wang S, Thoolen M, Mangelsdorf DJ, Lustig KD, Shan B 2000 Role of LXRs in control of lipogenesis. Genes Dev 14:2831-2838
-
(2000)
Genes Dev
, vol.14
, pp. 2831-2838
-
-
Schultz, J.R.1
Tu, H.2
Luk, A.3
Repa, J.J.4
Medina, J.C.5
Li, L.6
Schwendner, S.7
Wang, S.8
Thoolen, M.9
Mangelsdorf, D.J.10
Lustig, K.D.11
Shan, B.12
-
6
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ
-
Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro JM, Shimomura I, Shan B, Brown MS, Goldstein JL, Mangelsdorf DJ 2000 Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ. Genes Dev 14:2819-2830
-
(2000)
Genes Dev
, vol.14
, pp. 2819-2830
-
-
Repa, J.J.1
Liang, G.2
Ou, J.3
Bashmakov, Y.4
Lobaccaro, J.M.5
Shimomura, I.6
Shan, B.7
Brown, M.S.8
Goldstein, J.L.9
Mangelsdorf, D.J.10
-
7
-
-
0035047709
-
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory elementbinding protein 1c gene promoter
-
Yoshikawa T, Shimano H, Amemiya-Kudo M, Yahagi N, Hasty AH, Matsuzaka T, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Kimura S, Ishibashi S, Yamada N 2001 Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory elementbinding protein 1c gene promoter. Mol Cell Biol 21:2991-3000
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2991-3000
-
-
Yoshikawa, T.1
Shimano, H.2
Amemiya-Kudo, M.3
Yahagi, N.4
Hasty, A.H.5
Matsuzaka, T.6
Okazaki, H.7
Tamura, Y.8
Iizuka, Y.9
Ohashi, K.10
Osuga, J.11
Harada, K.12
Gotoda, T.13
Kimura, S.14
Ishibashi, S.15
Yamada, N.16
-
8
-
-
0037192797
-
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors
-
Joseph SB, Laffitte BA, Patel PH, Watson MA, Matsukuma KE, Walczak R, Collins JL, Osborne TF, Tontonoz P 2002 Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J Biol Chem 277:11019-11025
-
(2002)
J Biol Chem
, vol.277
, pp. 11019-11025
-
-
Joseph, S.B.1
Laffitte, B.A.2
Patel, P.H.3
Watson, M.A.4
Matsukuma, K.E.5
Walczak, R.6
Collins, J.L.7
Osborne, T.F.8
Tontonoz, P.9
-
9
-
-
14444285707
-
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
-
Lehmann JM, Kliewer SA, Moore LB, Smith-Oliver TA, Oliver BB, Su JL, Sundseth SS, Winegar DA, Blanchard DE, Spencer TA, Willson TM 1997 Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. J Biol Chem 272:3137-3140
-
(1997)
J Biol Chem
, vol.272
, pp. 3137-3140
-
-
Lehmann, J.M.1
Kliewer, S.A.2
Moore, L.B.3
Smith-Oliver, T.A.4
Oliver, B.B.5
Su, J.L.6
Sundseth, S.S.7
Winegar, D.A.8
Blanchard, D.E.9
Spencer, T.A.10
Willson, T.M.11
-
10
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα
-
Peet DJ, Turley SD, Ma W, Janowski BA, Lobaccaro JM, Hammer RE, Mangelsdorf DJ 1998 Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα. Cell 93:693-704
-
(1998)
Cell
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.M.5
Hammer, R.E.6
Mangelsdorf, D.J.7
-
11
-
-
0037166261
-
Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors α and β
-
Repa JJ, Berge KE, Pomajzl C, Richardson JA, Hobbs H, Mangelsdorf DJ 2002 Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors α and β. J Biol Chem 277:18793-18800
-
(2002)
J Biol Chem
, vol.277
, pp. 18793-18800
-
-
Repa, J.J.1
Berge, K.E.2
Pomajzl, C.3
Richardson, J.A.4
Hobbs, H.5
Mangelsdorf, D.J.6
-
12
-
-
0034710965
-
Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα
-
USA
-
Venkateswaran A, Laffitte BA, Joseph SB, Mak PA, Wilpitz DC, Edwards PA, Tontonoz P 2000 Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα. Proc Natl Acad Sci USA 97:12097-12102
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 12097-12102
-
-
Venkateswaran, A.1
Laffitte, B.A.2
Joseph, S.B.3
Mak, P.A.4
Wilpitz, D.C.5
Edwards, P.A.6
Tontonoz, P.7
-
13
-
-
0037199994
-
Regulated expression of the ApoE/C-I/C-IV/C-II gene cluster in murine and human macrophages: A critical role for the nuclear receptors LXRα and LXRβ
-
Mak PA, Laffitte BA, Desrumaux C, Joseph SB, Curtiss LK, Mangelsdorf DJ, Tontonoz P, Edwards PA 2002 Regulated expression of the ApoE/C-I/C-IV/C-II gene cluster in murine and human macrophages: A critical role for the nuclear receptors LXRα and LXRβ. J Biol Chem 277:31900-31908
-
(2002)
J Biol Chem
, vol.277
, pp. 31900-31908
-
-
Mak, P.A.1
Laffitte, B.A.2
Desrumaux, C.3
Joseph, S.B.4
Curtiss, L.K.5
Mangelsdorf, D.J.6
Tontonoz, P.7
Edwards, P.A.8
-
14
-
-
0035895202
-
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes
-
USA
-
Laffitte BA, Repa JJ, Joseph SB, Wilpitz DC, Kast HR, Mangelsdorf DJ, Tontonoz P 2001 LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. Proc Natl Acad Sci USA 98:507-512
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 507-512
-
-
Laffitte, B.A.1
Repa, J.J.2
Joseph, S.B.3
Wilpitz, D.C.4
Kast, H.R.5
Mangelsdorf, D.J.6
Tontonoz, P.7
-
15
-
-
0033997752
-
Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element
-
Luo Y, Tall AR 2000 Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element. J Clin Invest 105:513-520
-
(2000)
J Clin Invest
, vol.105
, pp. 513-520
-
-
Luo, Y.1
Tall, A.R.2
-
16
-
-
0035900749
-
Regulation of lipoprotein lipase by the oxysterol receptors, LXRα and LXRβ
-
Zhang Y, Repa JJ, Gauthier K, Mangelsdorf DJ 2001 Regulation of lipoprotein lipase by the oxysterol receptors, LXRα and LXRβ. J Biol Chem 276:43018-43024
-
(2001)
J Biol Chem
, vol.276
, pp. 43018-43024
-
-
Zhang, Y.1
Repa, J.J.2
Gauthier, K.3
Mangelsdorf, D.J.4
-
17
-
-
0033555551
-
Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression
-
McKay RA, Miraglia LJ, Cummins LL, Owens SR, Sasmor H, Dean NM 1999 Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression. J Biol Chem 274:1715-1722
-
(1999)
J Biol Chem
, vol.274
, pp. 1715-1722
-
-
McKay, R.A.1
Miraglia, L.J.2
Cummins, L.L.3
Owens, S.R.4
Sasmor, H.5
Dean, N.M.6
-
18
-
-
0019742075
-
Assay of peroxisomal β-oxidation of fatty acids
-
Lazarow PB 1981 Assay of peroxisomal β-oxidation of fatty acids. Methods Enzymol 72:315-319
-
(1981)
Methods Enzymol
, vol.72
, pp. 315-319
-
-
Lazarow, P.B.1
-
19
-
-
0034453225
-
Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-α
-
Tobin KA, Steineger HH, Alberti S, Spydevold O, Auwerx J, Gustafsson JA, Nebb HI 2000 Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-α. Mol Endocrinol 14:741-752
-
(2000)
Mol Endocrinol
, vol.14
, pp. 741-752
-
-
Tobin, K.A.1
Steineger, H.H.2
Alberti, S.3
Spydevold, O.4
Auwerx, J.5
Gustafsson, J.A.6
Nebb, H.I.7
-
20
-
-
0035138625
-
PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
-
Chinetti G, Lestavel S, Bocher V, Remaley AT, Neve B, Torra IP, Teissier E, Minnich A, Jaye M, Duverger N, Brewer HB, Fruchart JC, Clavey V, Staels B 2001 PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat Med 7:53-58
-
(2001)
Nat Med
, vol.7
, pp. 53-58
-
-
Chinetti, G.1
Lestavel, S.2
Bocher, V.3
Remaley, A.T.4
Neve, B.5
Torra, I.P.6
Teissier, E.7
Minnich, A.8
Jaye, M.9
Duverger, N.10
Brewer, H.B.11
Fruchart, J.C.12
Clavey, V.13
Staels, B.14
-
21
-
-
17744376173
-
A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
-
Chawla A, Boisvert WA, Lee CH, Laffitte BA, Barak Y, Joseph SB, Liao D, Nagy L, Edwards PA, Curtiss LK, Evans RM, Tontonoz P 2001 A PPARγ-LXR- ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol Cell 7:161-171
-
(2001)
Mol Cell
, vol.7
, pp. 161-171
-
-
Chawla, A.1
Boisvert, W.A.2
Lee, C.H.3
Laffitte, B.A.4
Barak, Y.5
Joseph, S.B.6
Liao, D.7
Nagy, L.8
Edwards, P.A.9
Curtiss, L.K.10
Evans, R.M.11
Tontonoz, P.12
-
22
-
-
0037131347
-
Phospholipid transfer protein is regulated by liver X receptors in vivo
-
Cao G, Beyer TP, Yang XP, Schmidt RJ, Zhang Y, Bensch WR, Kauffman RF, Gao H, Ryan TP, Liang Y, Eacho PI, Jiang XC 2002 Phospholipid transfer protein is regulated by liver X receptors in vivo. J Biol Chem 277:39561-39565
-
(2002)
J Biol Chem
, vol.277
, pp. 39561-39565
-
-
Cao, G.1
Beyer, T.P.2
Yang, X.P.3
Schmidt, R.J.4
Zhang, Y.5
Bensch, W.R.6
Kauffman, R.F.7
Gao, H.8
Ryan, T.P.9
Liang, Y.10
Eacho, P.I.11
Jiang, X.C.12
-
23
-
-
3442895325
-
Liver X receptors (LXRs) regulate apolipoprotein AIV-implications of the antiatherosclerotic effect of LXR agonists
-
Liang Y, Jiang XC, Liu R, Liang G, Beyer TP, Gao H, Ryan TP, Dan Li S, Eacho PI, Cao G 2004 Liver X receptors (LXRs) regulate apolipoprotein AIV-implications of the antiatherosclerotic effect of LXR agonists. Mol Endocrinol 18:2000-2010
-
(2004)
Mol Endocrinol
, vol.18
, pp. 2000-2010
-
-
Liang, Y.1
Jiang, X.C.2
Liu, R.3
Liang, G.4
Beyer, T.P.5
Gao, H.6
Ryan, T.P.7
Dan Li, S.8
Eacho, P.I.9
Cao, G.10
-
24
-
-
0036896653
-
Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue
-
Stulnig TM, Steffensen KR, Gao H, Reimers M, Dahlman-Wright K, Schuster GU, Gustafsson JA 2002 Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue. Mol Pharmacol 62:1299-1305
-
(2002)
Mol Pharmacol
, vol.62
, pp. 1299-1305
-
-
Stulnig, T.M.1
Steffensen, K.R.2
Gao, H.3
Reimers, M.4
Dahlman-Wright, K.5
Schuster, G.U.6
Gustafsson, J.A.7
-
25
-
-
9444234519
-
Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor α, retinoid X receptor, and liver X receptor in mouse liver
-
Anderson SP, Dunn C, Laughter A, Yoon L, Swanson C, Stulnig TM, Steffensen KR, Chandraratna RA, Gustafsson JA, Corton JC 2004 Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor α, retinoid X receptor, and liver X receptor in mouse liver. Mol Pharmacol 66:1440-1452
-
(2004)
Mol Pharmacol
, vol.66
, pp. 1440-1452
-
-
Anderson, S.P.1
Dunn, C.2
Laughter, A.3
Yoon, L.4
Swanson, C.5
Stulnig, T.M.6
Steffensen, K.R.7
Chandraratna, R.A.8
Gustafsson, J.A.9
Corton, J.C.10
-
26
-
-
0034668147
-
Regulation of the peroxisomal β-oxidation-dependent pathway by peroxisome proliferator-activated receptor α and kinases
-
Latruffe N, Malki MC, Nicolas-Frances V, Clemencet MC, Jannin B, Berlot JP 2000 Regulation of the peroxisomal β-oxidation-dependent pathway by peroxisome proliferator-activated receptor α and kinases. Biochem Pharmacol 60:1027-1032
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1027-1032
-
-
Latruffe, N.1
Malki, M.C.2
Nicolas-Frances, V.3
Clemencet, M.C.4
Jannin, B.5
Berlot, J.P.6
-
27
-
-
0029035278
-
LXR, a nuclear receptor that defines a distinct retinoid response pathway
-
Willy PJ, Umesono K, Ong ES, Evans RM, Heyman RA, Mangelsdorf DJ 1995 LXR, a nuclear receptor that defines a distinct retinoid response pathway. Genes Dev 9:1033-1045
-
(1995)
Genes Dev
, vol.9
, pp. 1033-1045
-
-
Willy, P.J.1
Umesono, K.2
Ong, E.S.3
Evans, R.M.4
Heyman, R.A.5
Mangelsdorf, D.J.6
-
28
-
-
0031042762
-
Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR
-
Willy PJ, Mangelsdorf DJ 1997 Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR. Genes Dev 11:289-298
-
(1997)
Genes Dev
, vol.11
, pp. 289-298
-
-
Willy, P.J.1
Mangelsdorf, D.J.2
-
29
-
-
0035101931
-
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRβ-deficient mice
-
Alberti S, Schuster G, Parini P, Feltkamp D, Diczfalusy U, Rudling M, Angelin B, Bjorkhem I, Pettersson S, Gustafsson JA 2001 Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRβ-deficient mice. J Clin Invest 107:565-573
-
(2001)
J Clin Invest
, vol.107
, pp. 565-573
-
-
Alberti, S.1
Schuster, G.2
Parini, P.3
Feltkamp, D.4
Diczfalusy, U.5
Rudling, M.6
Angelin, B.7
Bjorkhem, I.8
Pettersson, S.9
Gustafsson, J.A.10
|