In vitro metabolism of 8-2 fluorotelomer alcohol: Interspecies comparisons and metabolic pathway refinement

Toxicological Sciences

Volumn 100, Issue 2, 2007, Pages 333-344

  Nabb, Diane L ^a   Szostek, Bogdan ^a   Himmelstein, Matthew W ^a   Mawn, Michael P ^a   Gargas, Michael I ^b   Sweeney, Lisa M ^b   Stadler, Judith C ^a   Buck, Robert C ^a   Fasano, William J ^a  

^a DUPONT COMPANY   (United States)

^b Sapphire Group   (United States)

Author keywords

8 2 fluorotelomer alcohol; Fluorotelomer aldehydes; Glutathione conjugates; Hepatic clearance; Hepatocytes; Microsomes; Perfluorinated carboxylic acids; Perfluorononanoic acid; Perfluorooctanoate; Taurine conjugates

Indexed keywords

FLUOROTELOMER ALCOHOL; INDUSTRIAL CHEMICAL; PERFLUORO COMPOUND; PERFLUOROOCTANOIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENVIRONMENTAL EXPOSURE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER MICROSOME; MALE; MOUSE; NONHUMAN; RAT; SPECIES COMPARISON; SPECIES DIFFERENTIATION; SPRAGUE DAWLEY RAT; STRUCTURE ANALYSIS; TOXICOKINETICS; TROUT;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CYTOSOL; ENVIRONMENTAL POLLUTANTS; FATTY ALCOHOLS; FLUOROCARBONS; HEPATOCYTES; HUMANS; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED STRAINS; MICROSOMES, LIVER; OCTANOIC ACIDS; ONCORHYNCHUS MYKISS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY;

MUS; RATTUS; SALMONIDAE;

EID: 36248985670     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm230     Document Type: Article

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