Differential hepatic effects of perfluorobutyrate mediated by mouse and human PPAR-α

Toxicological Sciences

Volumn 110, Issue 1, 2009, Pages 204-211

  Foreman, Jennifer E ^a   Chang, Shu Ching ^b   Ehresman, David J ^b   Butenhoff, John L ^b   Anderson, Cherie R ^a   Palkar, Prajakta S ^a   Kang, Boo Hyon ^c   Gonzalez, Frank J ^d   Peters, Jeffrey M ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b 3M COMPANY   (United States)

^c Non Clinical Pathology Research Center   (South Korea)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Liver; PFBA; PPAR ; Receptor

Indexed keywords

CYCLIN D1; CYTOCHROME P450 2B; CYTOCHROME P450 2B10; CYTOCHROME P450 3A11; MYC PROTEIN; PERFLUORO COMPOUND; PERFLUOROBUTRYATE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL INFILTRATION; CELL VACUOLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HEPATOMEGALY; INFLAMMATORY CELL; LIPID METABOLISM; LIVER CELL; LIVER HYPERTROPHY; LIVER NECROSIS; LIVER TOXICITY; LIVER WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; UPREGULATION;

ALANINE TRANSAMINASE; ANIMALS; BODY WEIGHT; FLUOROCARBONS; HEPATITIS, TOXIC; HUMANS; LIVER; MALE; MICE; MICE, TRANSGENIC; ORGAN SIZE; PPAR ALPHA; PYRIMIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

MUS;

EID: 67649236155     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp077     Document Type: Article

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