메뉴 건너뛰기




Volumn 21, Issue 4, 2011, Pages 422-430

Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: To die or not to die, that is the question

Author keywords

[No Author keywords available]

Indexed keywords

RNA HELICASE;

EID: 79960902609     PISSN: 0959437X     EISSN: 18790380     Source Type: Journal    
DOI: 10.1016/j.gde.2011.03.008     Document Type: Review
Times cited : (109)

References (82)
  • 2
    • 78649720695 scopus 로고    scopus 로고
    • Cutting the nonsense: the degradation of PTC-containing mRNAs
    • Nicholson P., Mühlemann O. Cutting the nonsense: the degradation of PTC-containing mRNAs. Biochem Soc Trans 2010, 38:1615-1620.
    • (2010) Biochem Soc Trans , vol.38 , pp. 1615-1620
    • Nicholson, P.1    Mühlemann, O.2
  • 4
    • 48349096177 scopus 로고    scopus 로고
    • Widespread impact of nonsense-mediated mRNA decay on the yeast intronome
    • Sayani S., Janis M., Lee C.Y., Toesca I., Chanfreau G.F. Widespread impact of nonsense-mediated mRNA decay on the yeast intronome. Mol Cell 2008, 31:360-370.
    • (2008) Mol Cell , vol.31 , pp. 360-370
    • Sayani, S.1    Janis, M.2    Lee, C.Y.3    Toesca, I.4    Chanfreau, G.F.5
  • 5
    • 20144369898 scopus 로고    scopus 로고
    • MRNA surveillance of expressed pseudogenes in C. elegans
    • Mitrovich Q.M., Anderson P. mRNA surveillance of expressed pseudogenes in C. elegans. Curr Biol 2005, 15:963-967.
    • (2005) Curr Biol , vol.15 , pp. 963-967
    • Mitrovich, Q.M.1    Anderson, P.2
  • 6
    • 37849005006 scopus 로고    scopus 로고
    • NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity
    • Chamieh H., Ballut L., Bonneau F., Le Hir H. NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity. Nat Struct Mol Biol 2008, 15:85-93.
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 85-93
    • Chamieh, H.1    Ballut, L.2    Bonneau, F.3    Le Hir, H.4
  • 8
    • 78649949096 scopus 로고    scopus 로고
    • Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense-mediated mRNA decay
    • Franks T.M., Singh G., Lykke-Andersen J. Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense-mediated mRNA decay. Cell 2010, 143:938-950.
    • (2010) Cell , vol.143 , pp. 938-950
    • Franks, T.M.1    Singh, G.2    Lykke-Andersen, J.3
  • 9
    • 0034043404 scopus 로고    scopus 로고
    • Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p
    • Maderazo A.B., He F., Mangus D.A., Jacobson A. Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p. Mol Cell Biol 2000, 20:4591-4603.
    • (2000) Mol Cell Biol , vol.20 , pp. 4591-4603
    • Maderazo, A.B.1    He, F.2    Mangus, D.A.3    Jacobson, A.4
  • 11
    • 25844512736 scopus 로고    scopus 로고
    • Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements
    • Gehring N.H., Kunz J.B., Neu-Yilik G., Breit S., Viegas M.H., Hentze M.W., Kulozik A.E. Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. Mol Cell 2005, 20:65-75.
    • (2005) Mol Cell , vol.20 , pp. 65-75
    • Gehring, N.H.1    Kunz, J.B.2    Neu-Yilik, G.3    Breit, S.4    Viegas, M.H.5    Hentze, M.W.6    Kulozik, A.E.7
  • 12
    • 58149520665 scopus 로고    scopus 로고
    • SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs
    • Gong C., Kim Y.K., Woeller C.F., Tang Y., Maquat L.E. SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. Genes Dev 2009, 23:54-66.
    • (2009) Genes Dev , vol.23 , pp. 54-66
    • Gong, C.1    Kim, Y.K.2    Woeller, C.F.3    Tang, Y.4    Maquat, L.E.5
  • 13
    • 46149112362 scopus 로고    scopus 로고
    • Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay
    • Saltzman A.L., Kim Y.K., Pan Q., Fagnani M.M., Maquat L.E., Blencowe B.J. Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay. Mol Cell Biol 2008, 28:4320-4330.
    • (2008) Mol Cell Biol , vol.28 , pp. 4320-4330
    • Saltzman, A.L.1    Kim, Y.K.2    Pan, Q.3    Fagnani, M.M.4    Maquat, L.E.5    Blencowe, B.J.6
  • 14
    • 33646865949 scopus 로고    scopus 로고
    • Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation
    • Kunz J.B., Neu-Yilik G., Hentze M.W., Kulozik A.E., Gehring N.H. Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation. RNA 2006, 12:1015-1022.
    • (2006) RNA , vol.12 , pp. 1015-1022
    • Kunz, J.B.1    Neu-Yilik, G.2    Hentze, M.W.3    Kulozik, A.E.4    Gehring, N.H.5
  • 15
    • 0036645697 scopus 로고    scopus 로고
    • The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling
    • Lejeune F., Ishigaki Y., Li X., Maquat L.E. The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling. EMBO J 2002, 21:3536-3545.
    • (2002) EMBO J , vol.21 , pp. 3536-3545
    • Lejeune, F.1    Ishigaki, Y.2    Li, X.3    Maquat, L.E.4
  • 16
    • 0034751160 scopus 로고    scopus 로고
    • Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)
    • Serin G., Gersappe A., Black J.D., Aronoff R., Maquat L.E. Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4). Mol Cell Biol 2001, 21:209-223.
    • (2001) Mol Cell Biol , vol.21 , pp. 209-223
    • Serin, G.1    Gersappe, A.2    Black, J.D.3    Aronoff, R.4    Maquat, L.E.5
  • 18
    • 77955326776 scopus 로고    scopus 로고
    • The pioneer round of translation: features and functions
    • Maquat L.E., Tarn W.Y., Isken O. The pioneer round of translation: features and functions. Cell 2010, 142:368-374.
    • (2010) Cell , vol.142 , pp. 368-374
    • Maquat, L.E.1    Tarn, W.Y.2    Isken, O.3
  • 19
    • 77949904260 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors
    • Nicholson P., Yepiskoposyan H., Metze S., Zamudio Orozco R., Kleinschmidt N., Mühlemann O. Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors. Cell Mol Life Sci 2010, 67:677-700.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 677-700
    • Nicholson, P.1    Yepiskoposyan, H.2    Metze, S.3    Zamudio Orozco, R.4    Kleinschmidt, N.5    Mühlemann, O.6
  • 20
    • 1842473091 scopus 로고    scopus 로고
    • The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3
    • Kadlec J., Izaurralde E., Cusack S. The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3. Nat Struct Mol Biol 2004, 11:330-337.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 330-337
    • Kadlec, J.1    Izaurralde, E.2    Cusack, S.3
  • 21
    • 0032104190 scopus 로고    scopus 로고
    • A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance
    • Nagy E., Maquat L.E. A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance. Trends Biochem Sci 1998, 23:198-199.
    • (1998) Trends Biochem Sci , vol.23 , pp. 198-199
    • Nagy, E.1    Maquat, L.E.2
  • 23
    • 34948854852 scopus 로고    scopus 로고
    • Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA
    • Matsuda D., Hosoda N., Kim Y.K., Maquat L.E. Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA. Nat Struct Mol Biol 2007, 14:974-979.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 974-979
    • Matsuda, D.1    Hosoda, N.2    Kim, Y.K.3    Maquat, L.E.4
  • 24
    • 43249093760 scopus 로고    scopus 로고
    • Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region
    • Eberle A.B., Stalder L., Mathys H., Orozco R.Z., Mühlemann O. Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region. PLoS Biol 2008, 6:e92.
    • (2008) PLoS Biol , vol.6
    • Eberle, A.B.1    Stalder, L.2    Mathys, H.3    Orozco, R.Z.4    Mühlemann, O.5
  • 25
    • 43249084802 scopus 로고    scopus 로고
    • A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay
    • Singh G., Rebbapragada I., Lykke-Andersen J. A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay. PLoS Biol 2008, 6:e111.
    • (2008) PLoS Biol , vol.6
    • Singh, G.1    Rebbapragada, I.2    Lykke-Andersen, J.3
  • 26
    • 77951976646 scopus 로고    scopus 로고
    • Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe
    • Wen J., Brogna S. Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe. EMBO J 2010, 29:1537-1551.
    • (2010) EMBO J , vol.29 , pp. 1537-1551
    • Wen, J.1    Brogna, S.2
  • 28
    • 34547413345 scopus 로고    scopus 로고
    • Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components
    • Zhang Z., Krainer A.R. Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components. Proc Natl Acad Sci U S A 2007, 104:11574-11579.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 11574-11579
    • Zhang, Z.1    Krainer, A.R.2
  • 29
    • 0042025014 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways
    • Gatfield D., Unterholzner L., Ciccarelli F.D., Bork P., Izaurralde E. Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways. EMBO J 2003, 22:3960-3970.
    • (2003) EMBO J , vol.22 , pp. 3960-3970
    • Gatfield, D.1    Unterholzner, L.2    Ciccarelli, F.D.3    Bork, P.4    Izaurralde, E.5
  • 30
    • 33846015866 scopus 로고    scopus 로고
    • Functions of the nonsense-mediated mRNA decay pathway in Drosophila development
    • Metzstein M.M., Krasnow M.A. Functions of the nonsense-mediated mRNA decay pathway in Drosophila development. PLoS Genet 2006, 2:e180.
    • (2006) PLoS Genet , vol.2
    • Metzstein, M.M.1    Krasnow, M.A.2
  • 31
    • 1442354190 scopus 로고    scopus 로고
    • An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay
    • Palacios I.M., Gatfield D., St Johnston D., Izaurralde E. An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay. Nature 2004, 427:753-757.
    • (2004) Nature , vol.427 , pp. 753-757
    • Palacios, I.M.1    Gatfield, D.2    St Johnston, D.3    Izaurralde, E.4
  • 32
    • 34247556560 scopus 로고    scopus 로고
    • Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway
    • Longman D., Plasterk R.H., Johnstone I.L., Cáceres J.F. Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway. Genes Dev 2007, 21:1075-1085.
    • (2007) Genes Dev , vol.21 , pp. 1075-1085
    • Longman, D.1    Plasterk, R.H.2    Johnstone, I.L.3    Cáceres, J.F.4
  • 33
    • 33745817833 scopus 로고    scopus 로고
    • UPF1 is required for nonsense-mediated mRNA decay (NMD) and RNAi in Arabidopsis
    • Arciga-Reyes L., Wootton L., Kieffer M., Davies B. UPF1 is required for nonsense-mediated mRNA decay (NMD) and RNAi in Arabidopsis. Plant J 2006, 47:480-489.
    • (2006) Plant J , vol.47 , pp. 480-489
    • Arciga-Reyes, L.1    Wootton, L.2    Kieffer, M.3    Davies, B.4
  • 35
    • 33750292061 scopus 로고    scopus 로고
    • NMD and the evolution of eukaryotic gene structure
    • Landes Bioscience, L.E. Maquat (Ed.)
    • Lynch M., Hong X., Scofield D.G. NMD and the evolution of eukaryotic gene structure. Nonsense-mediated mRNA decay 2006, 197-211. Landes Bioscience. L.E. Maquat (Ed.).
    • (2006) Nonsense-mediated mRNA decay , pp. 197-211
    • Lynch, M.1    Hong, X.2    Scofield, D.G.3
  • 36
    • 27144478105 scopus 로고    scopus 로고
    • CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells
    • Hosoda N., Kim Y.K., Lejeune F., Maquat L.E. CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells. Nat Struct Mol Biol 2005, 12:893-901.
    • (2005) Nat Struct Mol Biol , vol.12 , pp. 893-901
    • Hosoda, N.1    Kim, Y.K.2    Lejeune, F.3    Maquat, L.E.4
  • 37
    • 77955339642 scopus 로고    scopus 로고
    • UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps
    • Hwang J., Sato H., Tang Y., Matsuda D., Maquat L.E. UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps. Mol Cell 2010, 39:396-409.
    • (2010) Mol Cell , vol.39 , pp. 396-409
    • Hwang, J.1    Sato, H.2    Tang, Y.3    Matsuda, D.4    Maquat, L.E.5
  • 38
    • 32044435368 scopus 로고    scopus 로고
    • Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay
    • Kashima I., Yamashita A., Izumi N., Kataoka N., Morishita R., Hoshino S., Ohno M., Dreyfuss G., Ohno S. Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. Genes Dev 2006, 20:355-367.
    • (2006) Genes Dev , vol.20 , pp. 355-367
    • Kashima, I.1    Yamashita, A.2    Izumi, N.3    Kataoka, N.4    Morishita, R.5    Hoshino, S.6    Ohno, M.7    Dreyfuss, G.8    Ohno, S.9
  • 39
    • 65449178454 scopus 로고    scopus 로고
    • SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay
    • Yamashita A., Izumi N., Kashima I., Ohnishi T., Saari B., Katsuhata Y., Muramatsu R., Morita T., Iwamatsu A., Hachiya T., et al. SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. Genes Dev 2009, 23:1091-1105.
    • (2009) Genes Dev , vol.23 , pp. 1091-1105
    • Yamashita, A.1    Izumi, N.2    Kashima, I.3    Ohnishi, T.4    Saari, B.5    Katsuhata, Y.6    Muramatsu, R.7    Morita, T.8    Iwamatsu, A.9    Hachiya, T.10
  • 40
    • 41949113083 scopus 로고    scopus 로고
    • Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay
    • Isken O., Kim Y.K., Hosoda N., Mayeur G.L., Hershey J.W., Maquat L.E. Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay. Cell 2008, 133:314-327.
    • (2008) Cell , vol.133 , pp. 314-327
    • Isken, O.1    Kim, Y.K.2    Hosoda, N.3    Mayeur, G.L.4    Hershey, J.W.5    Maquat, L.E.6
  • 41
    • 0037415691 scopus 로고    scopus 로고
    • SMG-5, required for C. elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A
    • Anders K.R., Grimson A., Anderson P. SMG-5, required for C. elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A. EMBO J 2003, 22:641-650.
    • (2003) EMBO J , vol.22 , pp. 641-650
    • Anders, K.R.1    Grimson, A.2    Anderson, P.3
  • 43
    • 0032771414 scopus 로고    scopus 로고
    • SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast
    • Page M.F., Carr B., Anders K.R., Grimson A., Anderson P. SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast. Mol Cell Biol 1999, 19:5943-5951.
    • (1999) Mol Cell Biol , vol.19 , pp. 5943-5951
    • Page, M.F.1    Carr, B.2    Anders, K.R.3    Grimson, A.4    Anderson, P.5
  • 44
    • 8544253956 scopus 로고    scopus 로고
    • A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay
    • Amrani N., Ganesan R., Kervestin S., Mangus D.A., Ghosh S., Jacobson A. A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay. Nature 2004, 432:112-118.
    • (2004) Nature , vol.432 , pp. 112-118
    • Amrani, N.1    Ganesan, R.2    Kervestin, S.3    Mangus, D.A.4    Ghosh, S.5    Jacobson, A.6
  • 45
    • 38149035044 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail
    • Meaux S., van Hoof A., Baker K.E. Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail. Mol Cell 2008, 29:134-140.
    • (2008) Mol Cell , vol.29 , pp. 134-140
    • Meaux, S.1    van Hoof, A.2    Baker, K.E.3
  • 46
    • 49949105213 scopus 로고    scopus 로고
    • The multiple lives of NMD factors: balancing roles in gene and genome regulation
    • Isken O., Maquat L.E. The multiple lives of NMD factors: balancing roles in gene and genome regulation. Nat Rev Genet 2008.
    • (2008) Nat Rev Genet
    • Isken, O.1    Maquat, L.E.2
  • 47
    • 78649741328 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay and development: shoot the messenger to survive?
    • Vicente-Crespo M., Palacios I.M. Nonsense-mediated mRNA decay and development: shoot the messenger to survive?. Biochem Soc Trans 2010, 38:1500-1505.
    • (2010) Biochem Soc Trans , vol.38 , pp. 1500-1505
    • Vicente-Crespo, M.1    Palacios, I.M.2
  • 48
    • 0032940802 scopus 로고    scopus 로고
    • Smg-7 is required for mRNA surveillance in Caenorhabditis elegans
    • Cali B.M., Kuchma S.L., Latham J., Anderson P. smg-7 is required for mRNA surveillance in Caenorhabditis elegans. Genetics 1999, 151:605-616.
    • (1999) Genetics , vol.151 , pp. 605-616
    • Cali, B.M.1    Kuchma, S.L.2    Latham, J.3    Anderson, P.4
  • 49
    • 0024444026 scopus 로고
    • A new kind of informational suppression in the nematode Caenorhabditis elegans
    • Hodgkin J., Papp A., Pulak R., Ambros V., Anderson P. A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics 1989, 123:301-313.
    • (1989) Genetics , vol.123 , pp. 301-313
    • Hodgkin, J.1    Papp, A.2    Pulak, R.3    Ambros, V.4    Anderson, P.5
  • 50
    • 79952651144 scopus 로고    scopus 로고
    • Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner
    • Avery P., Vicente-Crespo M., Francis D., Nashchekina O., Alonso C.R., Palacios I.M. Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner. RNA 2011, 17:624-638.
    • (2011) RNA , vol.17 , pp. 624-638
    • Avery, P.1    Vicente-Crespo, M.2    Francis, D.3    Nashchekina, O.4    Alonso, C.R.5    Palacios, I.M.6
  • 51
    • 25844454826 scopus 로고    scopus 로고
    • Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster
    • Chen Z., Smith K.R., Batterham P., Robin C. Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster. Genetics 2005, 171:403-406.
    • (2005) Genetics , vol.171 , pp. 403-406
    • Chen, Z.1    Smith, K.R.2    Batterham, P.3    Robin, C.4
  • 52
    • 25844435702 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets
    • Rehwinkel J., Letunic I., Raes J., Bork P., Izaurralde E. Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets. RNA 2005, 11:1530-1544.
    • (2005) RNA , vol.11 , pp. 1530-1544
    • Rehwinkel, J.1    Letunic, I.2    Raes, J.3    Bork, P.4    Izaurralde, E.5
  • 53
    • 57049126216 scopus 로고    scopus 로고
    • SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan
    • Huntzinger E., Kashima I., Fauser M., Saulière J., Izaurralde E. SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan. RNA 2008, 14:2609-2617.
    • (2008) RNA , vol.14 , pp. 2609-2617
    • Huntzinger, E.1    Kashima, I.2    Fauser, M.3    Saulière, J.4    Izaurralde, E.5
  • 54
    • 79955954056 scopus 로고    scopus 로고
    • Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish
    • doi:10.1093/nar/gkq1319
    • Anastasaki C, Longman D, Capper A, Patton EE, Cáceres JF: Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish. Nucleic Acids Res 2011, doi:10.1093/nar/gkq1319.
    • (2011) Nucleic Acids Res
    • Anastasaki, C.1    Longman, D.2    Capper, A.3    Patton, E.E.4    Cáceres, J.F.5
  • 55
  • 56
    • 77958509175 scopus 로고    scopus 로고
    • Coordinate regulation of histone mRNA metabolism and DNA replication: cyclin A/cdk1 is involved in inactivation of histone mRNA metabolism and DNA replication at the end of S phase
    • Koseoglu M.M., Dong J., Marzluff W.F. Coordinate regulation of histone mRNA metabolism and DNA replication: cyclin A/cdk1 is involved in inactivation of histone mRNA metabolism and DNA replication at the end of S phase. Cell Cycle 2010, 9:3857-3863.
    • (2010) Cell Cycle , vol.9 , pp. 3857-3863
    • Koseoglu, M.M.1    Dong, J.2    Marzluff, W.F.3
  • 60
    • 44349168303 scopus 로고    scopus 로고
    • Telomeres: the silence is broken
    • Azzalin C.M., Lingner J. Telomeres: the silence is broken. Cell Cycle 2008, 7:1161-1165.
    • (2008) Cell Cycle , vol.7 , pp. 1161-1165
    • Azzalin, C.M.1    Lingner, J.2
  • 61
    • 33745712580 scopus 로고    scopus 로고
    • Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation
    • Ciaudo C., Bourdet A., Cohen-Tannoudji M., Dietz H.C., Rougeulle C., Avner P. Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation. PLoS Genet 2006, 2:e94.
    • (2006) PLoS Genet , vol.2
    • Ciaudo, C.1    Bourdet, A.2    Cohen-Tannoudji, M.3    Dietz, H.C.4    Rougeulle, C.5    Avner, P.6
  • 64
    • 0037320770 scopus 로고    scopus 로고
    • Tissue-specific RNA surveillance? Nonsense-mediated mRNA decay causes collagen X haploinsufficiency in Schmid metaphyseal chondrodysplasia cartilage
    • Bateman J.F., Freddi S., Nattrass G., Savarirayan R. Tissue-specific RNA surveillance? Nonsense-mediated mRNA decay causes collagen X haploinsufficiency in Schmid metaphyseal chondrodysplasia cartilage. Hum Mol Genet 2003, 12:217-225.
    • (2003) Hum Mol Genet , vol.12 , pp. 217-225
    • Bateman, J.F.1    Freddi, S.2    Nattrass, G.3    Savarirayan, R.4
  • 65
    • 33748276752 scopus 로고    scopus 로고
    • A homozygous frameshift mutation in the ESCO2 gene: evidence of intertissue and interindividual variation in NMD efficiency
    • Resta N., Susca F.C., Di Giacomo M.C., Stella A., Bukvic N., Bagnulo R., Simone C., Guanti G. A homozygous frameshift mutation in the ESCO2 gene: evidence of intertissue and interindividual variation in NMD efficiency. J Cell Physiol 2006, 209:67-73.
    • (2006) J Cell Physiol , vol.209 , pp. 67-73
    • Resta, N.1    Susca, F.C.2    Di Giacomo, M.C.3    Stella, A.4    Bukvic, N.5    Bagnulo, R.6    Simone, C.7    Guanti, G.8
  • 67
    • 34547838641 scopus 로고    scopus 로고
    • The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense mediated decay pathway
    • Viegas M.H., Gehring N.H., Breit S., Hentze M.W., Kulozik A.E. The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense mediated decay pathway. Nucleic Acids Res 2007, 35:4542-4551.
    • (2007) Nucleic Acids Res , vol.35 , pp. 4542-4551
    • Viegas, M.H.1    Gehring, N.H.2    Breit, S.3    Hentze, M.W.4    Kulozik, A.E.5
  • 68
    • 32944458421 scopus 로고    scopus 로고
    • The human RNA surveillance factor UPF1 is required for S phase progression and genome stability
    • Azzalin C.M., Lingner J. The human RNA surveillance factor UPF1 is required for S phase progression and genome stability. Curr Biol 2006, 16:433-439.
    • (2006) Curr Biol , vol.16 , pp. 433-439
    • Azzalin, C.M.1    Lingner, J.2
  • 69
    • 37349043972 scopus 로고    scopus 로고
    • Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends
    • Azzalin C.M., Reichenbach P., Khoriauli L., Giulotto E., Lingner J. Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 2007, 318:798-801.
    • (2007) Science , vol.318 , pp. 798-801
    • Azzalin, C.M.1    Reichenbach, P.2    Khoriauli, L.3    Giulotto, E.4    Lingner, J.5
  • 70
    • 23344452109 scopus 로고    scopus 로고
    • Translation termination is involved in histone mRNA degradation when DNA replication is inhibited
    • Kaygun H., Marzluff W.F. Translation termination is involved in histone mRNA degradation when DNA replication is inhibited. Mol Cell Biol 2005, 25:6879-6888.
    • (2005) Mol Cell Biol , vol.25 , pp. 6879-6888
    • Kaygun, H.1    Marzluff, W.F.2
  • 71
    • 12944327374 scopus 로고    scopus 로고
    • Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay
    • Kim Y.K., Furic L., DesGroseillers L., Maquat L.E. Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay. Cell 2005, 120:195-208.
    • (2005) Cell , vol.120 , pp. 195-208
    • Kim, Y.K.1    Furic, L.2    DesGroseillers, L.3    Maquat, L.E.4
  • 74
    • 68249113593 scopus 로고    scopus 로고
    • Common mechanisms of PIKK regulation
    • Lovejoy C.A., Cortez D. Common mechanisms of PIKK regulation. DNA Repair (Amst) 2009, 8:1004-1008.
    • (2009) DNA Repair (Amst) , vol.8 , pp. 1004-1008
    • Lovejoy, C.A.1    Cortez, D.2
  • 75
    • 33749134437 scopus 로고    scopus 로고
    • DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation
    • Fuller-Pace F.V. DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation. Nucleic Acids Res 2006, 34:4206-4215.
    • (2006) Nucleic Acids Res , vol.34 , pp. 4206-4215
    • Fuller-Pace, F.V.1
  • 76
    • 0037279012 scopus 로고    scopus 로고
    • Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1
    • Chiu S.Y., Serin G., Ohara O., Maquat L.E. Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1. RNA 2003, 9:77-87.
    • (2003) RNA , vol.9 , pp. 77-87
    • Chiu, S.Y.1    Serin, G.2    Ohara, O.3    Maquat, L.E.4
  • 77
    • 78049447110 scopus 로고    scopus 로고
    • SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay
    • Kashima I., Jonas S., Jayachandran U., Buchwald G., Conti E., Lupas A.N., Izaurralde E. SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. Genes Dev 2010, 24:2440-2450.
    • (2010) Genes Dev , vol.24 , pp. 2440-2450
    • Kashima, I.1    Jonas, S.2    Jayachandran, U.3    Buchwald, G.4    Conti, E.5    Lupas, A.N.6    Izaurralde, E.7
  • 79
    • 8844245615 scopus 로고    scopus 로고
    • SMG7 acts as a molecular link between mRNA surveillance and mRNA decay
    • Unterholzner L., Izaurralde E. SMG7 acts as a molecular link between mRNA surveillance and mRNA decay. Mol Cell 2004, 16:587-596.
    • (2004) Mol Cell , vol.16 , pp. 587-596
    • Unterholzner, L.1    Izaurralde, E.2
  • 80
    • 56849103665 scopus 로고    scopus 로고
    • The control of mRNA decapping and P-body formation
    • Franks T.M., Lykke-Andersen J. The control of mRNA decapping and P-body formation. Mol Cell 2008, 32:605-615.
    • (2008) Mol Cell , vol.32 , pp. 605-615
    • Franks, T.M.1    Lykke-Andersen, J.2
  • 81
    • 0742288008 scopus 로고    scopus 로고
    • The enzymes and control of eukaryotic mRNA turnover
    • Parker R., Song H. The enzymes and control of eukaryotic mRNA turnover. Nat Struct Mol Biol 2004, 11:121-127.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 121-127
    • Parker, R.1    Song, H.2
  • 82
    • 52949089292 scopus 로고    scopus 로고
    • The exosome: a multipurpose RNA-decay machine
    • Schmid M., Jensen T.H. The exosome: a multipurpose RNA-decay machine. Trends Biochem Sci 2008, 33:501-510.
    • (2008) Trends Biochem Sci , vol.33 , pp. 501-510
    • Schmid, M.1    Jensen, T.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.