-
1
-
-
77956663450
-
NMD: RNA biology meets human genetic medicine
-
Bhuvanagiri M., Schlitter A.M., Hentze M.W., Kulozik A.E. NMD: RNA biology meets human genetic medicine. Biochem J 2010, 430:365-377.
-
(2010)
Biochem J
, vol.430
, pp. 365-377
-
-
Bhuvanagiri, M.1
Schlitter, A.M.2
Hentze, M.W.3
Kulozik, A.E.4
-
2
-
-
78649720695
-
Cutting the nonsense: the degradation of PTC-containing mRNAs
-
Nicholson P., Mühlemann O. Cutting the nonsense: the degradation of PTC-containing mRNAs. Biochem Soc Trans 2010, 38:1615-1620.
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 1615-1620
-
-
Nicholson, P.1
Mühlemann, O.2
-
3
-
-
38349125022
-
Translational control of intron splicing in eukaryotes
-
Jaillon O., Bouhouche K., Gout J.F., Aury J.M., Noel B., Saudemont B., Nowacki M., Serrano V., Porcel B.M., Segurens B., et al. Translational control of intron splicing in eukaryotes. Nature 2008, 451:359-362.
-
(2008)
Nature
, vol.451
, pp. 359-362
-
-
Jaillon, O.1
Bouhouche, K.2
Gout, J.F.3
Aury, J.M.4
Noel, B.5
Saudemont, B.6
Nowacki, M.7
Serrano, V.8
Porcel, B.M.9
Segurens, B.10
-
4
-
-
48349096177
-
Widespread impact of nonsense-mediated mRNA decay on the yeast intronome
-
Sayani S., Janis M., Lee C.Y., Toesca I., Chanfreau G.F. Widespread impact of nonsense-mediated mRNA decay on the yeast intronome. Mol Cell 2008, 31:360-370.
-
(2008)
Mol Cell
, vol.31
, pp. 360-370
-
-
Sayani, S.1
Janis, M.2
Lee, C.Y.3
Toesca, I.4
Chanfreau, G.F.5
-
5
-
-
20144369898
-
MRNA surveillance of expressed pseudogenes in C. elegans
-
Mitrovich Q.M., Anderson P. mRNA surveillance of expressed pseudogenes in C. elegans. Curr Biol 2005, 15:963-967.
-
(2005)
Curr Biol
, vol.15
, pp. 963-967
-
-
Mitrovich, Q.M.1
Anderson, P.2
-
6
-
-
37849005006
-
NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity
-
Chamieh H., Ballut L., Bonneau F., Le Hir H. NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity. Nat Struct Mol Biol 2008, 15:85-93.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 85-93
-
-
Chamieh, H.1
Ballut, L.2
Bonneau, F.3
Le Hir, H.4
-
7
-
-
79952686670
-
Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2
-
Chakrabarti S., Jayachandran U., Bonneau F., Fiorini F., Basquin C., Domcke S., Le Hir H., Conti E. Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2. Mol Cell 2011, 41:693-703.
-
(2011)
Mol Cell
, vol.41
, pp. 693-703
-
-
Chakrabarti, S.1
Jayachandran, U.2
Bonneau, F.3
Fiorini, F.4
Basquin, C.5
Domcke, S.6
Le Hir, H.7
Conti, E.8
-
8
-
-
78649949096
-
Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense-mediated mRNA decay
-
Franks T.M., Singh G., Lykke-Andersen J. Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense-mediated mRNA decay. Cell 2010, 143:938-950.
-
(2010)
Cell
, vol.143
, pp. 938-950
-
-
Franks, T.M.1
Singh, G.2
Lykke-Andersen, J.3
-
9
-
-
0034043404
-
Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p
-
Maderazo A.B., He F., Mangus D.A., Jacobson A. Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p. Mol Cell Biol 2000, 20:4591-4603.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4591-4603
-
-
Maderazo, A.B.1
He, F.2
Mangus, D.A.3
Jacobson, A.4
-
10
-
-
67650330563
-
A UPF3-mediated regulatory switch that maintains RNA surveillance
-
Chan W.K., Bhalla A.D., Le Hir H., Nguyen L.S., Huang L., Gecz J., Wilkinson M.F. A UPF3-mediated regulatory switch that maintains RNA surveillance. Nat Struct Mol Biol 2009, 16:747-753.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 747-753
-
-
Chan, W.K.1
Bhalla, A.D.2
Le Hir, H.3
Nguyen, L.S.4
Huang, L.5
Gecz, J.6
Wilkinson, M.F.7
-
11
-
-
25844512736
-
Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements
-
Gehring N.H., Kunz J.B., Neu-Yilik G., Breit S., Viegas M.H., Hentze M.W., Kulozik A.E. Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. Mol Cell 2005, 20:65-75.
-
(2005)
Mol Cell
, vol.20
, pp. 65-75
-
-
Gehring, N.H.1
Kunz, J.B.2
Neu-Yilik, G.3
Breit, S.4
Viegas, M.H.5
Hentze, M.W.6
Kulozik, A.E.7
-
12
-
-
58149520665
-
SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs
-
Gong C., Kim Y.K., Woeller C.F., Tang Y., Maquat L.E. SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. Genes Dev 2009, 23:54-66.
-
(2009)
Genes Dev
, vol.23
, pp. 54-66
-
-
Gong, C.1
Kim, Y.K.2
Woeller, C.F.3
Tang, Y.4
Maquat, L.E.5
-
13
-
-
46149112362
-
Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay
-
Saltzman A.L., Kim Y.K., Pan Q., Fagnani M.M., Maquat L.E., Blencowe B.J. Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay. Mol Cell Biol 2008, 28:4320-4330.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4320-4330
-
-
Saltzman, A.L.1
Kim, Y.K.2
Pan, Q.3
Fagnani, M.M.4
Maquat, L.E.5
Blencowe, B.J.6
-
14
-
-
33646865949
-
Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation
-
Kunz J.B., Neu-Yilik G., Hentze M.W., Kulozik A.E., Gehring N.H. Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation. RNA 2006, 12:1015-1022.
-
(2006)
RNA
, vol.12
, pp. 1015-1022
-
-
Kunz, J.B.1
Neu-Yilik, G.2
Hentze, M.W.3
Kulozik, A.E.4
Gehring, N.H.5
-
15
-
-
0036645697
-
The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling
-
Lejeune F., Ishigaki Y., Li X., Maquat L.E. The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling. EMBO J 2002, 21:3536-3545.
-
(2002)
EMBO J
, vol.21
, pp. 3536-3545
-
-
Lejeune, F.1
Ishigaki, Y.2
Li, X.3
Maquat, L.E.4
-
16
-
-
0034751160
-
Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)
-
Serin G., Gersappe A., Black J.D., Aronoff R., Maquat L.E. Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4). Mol Cell Biol 2001, 21:209-223.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 209-223
-
-
Serin, G.1
Gersappe, A.2
Black, J.D.3
Aronoff, R.4
Maquat, L.E.5
-
17
-
-
67650096774
-
Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival
-
Wittkopp N., Huntzinger E., Weiler C., Saulière J., Schmidt S., Sonawane M., Izaurralde E. Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival. Mol Cell Biol 2009, 29:3517-3528.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3517-3528
-
-
Wittkopp, N.1
Huntzinger, E.2
Weiler, C.3
Saulière, J.4
Schmidt, S.5
Sonawane, M.6
Izaurralde, E.7
-
18
-
-
77955326776
-
The pioneer round of translation: features and functions
-
Maquat L.E., Tarn W.Y., Isken O. The pioneer round of translation: features and functions. Cell 2010, 142:368-374.
-
(2010)
Cell
, vol.142
, pp. 368-374
-
-
Maquat, L.E.1
Tarn, W.Y.2
Isken, O.3
-
19
-
-
77949904260
-
Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors
-
Nicholson P., Yepiskoposyan H., Metze S., Zamudio Orozco R., Kleinschmidt N., Mühlemann O. Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors. Cell Mol Life Sci 2010, 67:677-700.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 677-700
-
-
Nicholson, P.1
Yepiskoposyan, H.2
Metze, S.3
Zamudio Orozco, R.4
Kleinschmidt, N.5
Mühlemann, O.6
-
20
-
-
1842473091
-
The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3
-
Kadlec J., Izaurralde E., Cusack S. The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3. Nat Struct Mol Biol 2004, 11:330-337.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 330-337
-
-
Kadlec, J.1
Izaurralde, E.2
Cusack, S.3
-
21
-
-
0032104190
-
A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance
-
Nagy E., Maquat L.E. A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance. Trends Biochem Sci 1998, 23:198-199.
-
(1998)
Trends Biochem Sci
, vol.23
, pp. 198-199
-
-
Nagy, E.1
Maquat, L.E.2
-
22
-
-
0036205348
-
Boundary-independent polar nonsense-mediated decay
-
Wang J., Gudikote J.P., Olivas O.R., Wilkinson M.F. Boundary-independent polar nonsense-mediated decay. EMBO Rep 2002, 3:274-279.
-
(2002)
EMBO Rep
, vol.3
, pp. 274-279
-
-
Wang, J.1
Gudikote, J.P.2
Olivas, O.R.3
Wilkinson, M.F.4
-
23
-
-
34948854852
-
Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA
-
Matsuda D., Hosoda N., Kim Y.K., Maquat L.E. Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA. Nat Struct Mol Biol 2007, 14:974-979.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 974-979
-
-
Matsuda, D.1
Hosoda, N.2
Kim, Y.K.3
Maquat, L.E.4
-
24
-
-
43249093760
-
Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region
-
Eberle A.B., Stalder L., Mathys H., Orozco R.Z., Mühlemann O. Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region. PLoS Biol 2008, 6:e92.
-
(2008)
PLoS Biol
, vol.6
-
-
Eberle, A.B.1
Stalder, L.2
Mathys, H.3
Orozco, R.Z.4
Mühlemann, O.5
-
25
-
-
43249084802
-
A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay
-
Singh G., Rebbapragada I., Lykke-Andersen J. A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay. PLoS Biol 2008, 6:e111.
-
(2008)
PLoS Biol
, vol.6
-
-
Singh, G.1
Rebbapragada, I.2
Lykke-Andersen, J.3
-
26
-
-
77951976646
-
Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe
-
Wen J., Brogna S. Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe. EMBO J 2010, 29:1537-1551.
-
(2010)
EMBO J
, vol.29
, pp. 1537-1551
-
-
Wen, J.1
Brogna, S.2
-
27
-
-
77957771429
-
The exon junction complex differentially marks spliced junctions
-
Saulière J., Haque N., Harms S., Barbosa I., Blanchette M., Le Hir H. The exon junction complex differentially marks spliced junctions. Nat Struct Mol Biol 2010, 17:1269-1271.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1269-1271
-
-
Saulière, J.1
Haque, N.2
Harms, S.3
Barbosa, I.4
Blanchette, M.5
Le Hir, H.6
-
28
-
-
34547413345
-
Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components
-
Zhang Z., Krainer A.R. Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components. Proc Natl Acad Sci U S A 2007, 104:11574-11579.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11574-11579
-
-
Zhang, Z.1
Krainer, A.R.2
-
29
-
-
0042025014
-
Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways
-
Gatfield D., Unterholzner L., Ciccarelli F.D., Bork P., Izaurralde E. Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways. EMBO J 2003, 22:3960-3970.
-
(2003)
EMBO J
, vol.22
, pp. 3960-3970
-
-
Gatfield, D.1
Unterholzner, L.2
Ciccarelli, F.D.3
Bork, P.4
Izaurralde, E.5
-
30
-
-
33846015866
-
Functions of the nonsense-mediated mRNA decay pathway in Drosophila development
-
Metzstein M.M., Krasnow M.A. Functions of the nonsense-mediated mRNA decay pathway in Drosophila development. PLoS Genet 2006, 2:e180.
-
(2006)
PLoS Genet
, vol.2
-
-
Metzstein, M.M.1
Krasnow, M.A.2
-
31
-
-
1442354190
-
An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay
-
Palacios I.M., Gatfield D., St Johnston D., Izaurralde E. An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay. Nature 2004, 427:753-757.
-
(2004)
Nature
, vol.427
, pp. 753-757
-
-
Palacios, I.M.1
Gatfield, D.2
St Johnston, D.3
Izaurralde, E.4
-
32
-
-
34247556560
-
Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway
-
Longman D., Plasterk R.H., Johnstone I.L., Cáceres J.F. Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway. Genes Dev 2007, 21:1075-1085.
-
(2007)
Genes Dev
, vol.21
, pp. 1075-1085
-
-
Longman, D.1
Plasterk, R.H.2
Johnstone, I.L.3
Cáceres, J.F.4
-
33
-
-
33745817833
-
UPF1 is required for nonsense-mediated mRNA decay (NMD) and RNAi in Arabidopsis
-
Arciga-Reyes L., Wootton L., Kieffer M., Davies B. UPF1 is required for nonsense-mediated mRNA decay (NMD) and RNAi in Arabidopsis. Plant J 2006, 47:480-489.
-
(2006)
Plant J
, vol.47
, pp. 480-489
-
-
Arciga-Reyes, L.1
Wootton, L.2
Kieffer, M.3
Davies, B.4
-
34
-
-
44649127573
-
Inter-kingdom conservation of mechanism of nonsense-mediated mRNA decay
-
Kerényi Z., Mérai Z., Hiripi L., Benkovics A., Gyula P., Lacomme C., Barta E., Nagy F., Silhavy D. Inter-kingdom conservation of mechanism of nonsense-mediated mRNA decay. EMBO J 2008, 27:1585-1595.
-
(2008)
EMBO J
, vol.27
, pp. 1585-1595
-
-
Kerényi, Z.1
Mérai, Z.2
Hiripi, L.3
Benkovics, A.4
Gyula, P.5
Lacomme, C.6
Barta, E.7
Nagy, F.8
Silhavy, D.9
-
35
-
-
33750292061
-
NMD and the evolution of eukaryotic gene structure
-
Landes Bioscience, L.E. Maquat (Ed.)
-
Lynch M., Hong X., Scofield D.G. NMD and the evolution of eukaryotic gene structure. Nonsense-mediated mRNA decay 2006, 197-211. Landes Bioscience. L.E. Maquat (Ed.).
-
(2006)
Nonsense-mediated mRNA decay
, pp. 197-211
-
-
Lynch, M.1
Hong, X.2
Scofield, D.G.3
-
36
-
-
27144478105
-
CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells
-
Hosoda N., Kim Y.K., Lejeune F., Maquat L.E. CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells. Nat Struct Mol Biol 2005, 12:893-901.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 893-901
-
-
Hosoda, N.1
Kim, Y.K.2
Lejeune, F.3
Maquat, L.E.4
-
37
-
-
77955339642
-
UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps
-
Hwang J., Sato H., Tang Y., Matsuda D., Maquat L.E. UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps. Mol Cell 2010, 39:396-409.
-
(2010)
Mol Cell
, vol.39
, pp. 396-409
-
-
Hwang, J.1
Sato, H.2
Tang, Y.3
Matsuda, D.4
Maquat, L.E.5
-
38
-
-
32044435368
-
Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay
-
Kashima I., Yamashita A., Izumi N., Kataoka N., Morishita R., Hoshino S., Ohno M., Dreyfuss G., Ohno S. Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. Genes Dev 2006, 20:355-367.
-
(2006)
Genes Dev
, vol.20
, pp. 355-367
-
-
Kashima, I.1
Yamashita, A.2
Izumi, N.3
Kataoka, N.4
Morishita, R.5
Hoshino, S.6
Ohno, M.7
Dreyfuss, G.8
Ohno, S.9
-
39
-
-
65449178454
-
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay
-
Yamashita A., Izumi N., Kashima I., Ohnishi T., Saari B., Katsuhata Y., Muramatsu R., Morita T., Iwamatsu A., Hachiya T., et al. SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. Genes Dev 2009, 23:1091-1105.
-
(2009)
Genes Dev
, vol.23
, pp. 1091-1105
-
-
Yamashita, A.1
Izumi, N.2
Kashima, I.3
Ohnishi, T.4
Saari, B.5
Katsuhata, Y.6
Muramatsu, R.7
Morita, T.8
Iwamatsu, A.9
Hachiya, T.10
-
40
-
-
41949113083
-
Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay
-
Isken O., Kim Y.K., Hosoda N., Mayeur G.L., Hershey J.W., Maquat L.E. Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay. Cell 2008, 133:314-327.
-
(2008)
Cell
, vol.133
, pp. 314-327
-
-
Isken, O.1
Kim, Y.K.2
Hosoda, N.3
Mayeur, G.L.4
Hershey, J.W.5
Maquat, L.E.6
-
41
-
-
0037415691
-
SMG-5, required for C. elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A
-
Anders K.R., Grimson A., Anderson P. SMG-5, required for C. elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A. EMBO J 2003, 22:641-650.
-
(2003)
EMBO J
, vol.22
, pp. 641-650
-
-
Anders, K.R.1
Grimson, A.2
Anderson, P.3
-
42
-
-
13944259434
-
SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway
-
Fukuhara N., Ebert J., Unterholzner L., Lindner D., Izaurralde E., Conti E. SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. Mol Cell 2005, 17:537-547.
-
(2005)
Mol Cell
, vol.17
, pp. 537-547
-
-
Fukuhara, N.1
Ebert, J.2
Unterholzner, L.3
Lindner, D.4
Izaurralde, E.5
Conti, E.6
-
43
-
-
0032771414
-
SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast
-
Page M.F., Carr B., Anders K.R., Grimson A., Anderson P. SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast. Mol Cell Biol 1999, 19:5943-5951.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5943-5951
-
-
Page, M.F.1
Carr, B.2
Anders, K.R.3
Grimson, A.4
Anderson, P.5
-
44
-
-
8544253956
-
A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay
-
Amrani N., Ganesan R., Kervestin S., Mangus D.A., Ghosh S., Jacobson A. A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay. Nature 2004, 432:112-118.
-
(2004)
Nature
, vol.432
, pp. 112-118
-
-
Amrani, N.1
Ganesan, R.2
Kervestin, S.3
Mangus, D.A.4
Ghosh, S.5
Jacobson, A.6
-
45
-
-
38149035044
-
Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail
-
Meaux S., van Hoof A., Baker K.E. Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail. Mol Cell 2008, 29:134-140.
-
(2008)
Mol Cell
, vol.29
, pp. 134-140
-
-
Meaux, S.1
van Hoof, A.2
Baker, K.E.3
-
46
-
-
49949105213
-
The multiple lives of NMD factors: balancing roles in gene and genome regulation
-
Isken O., Maquat L.E. The multiple lives of NMD factors: balancing roles in gene and genome regulation. Nat Rev Genet 2008.
-
(2008)
Nat Rev Genet
-
-
Isken, O.1
Maquat, L.E.2
-
47
-
-
78649741328
-
Nonsense-mediated mRNA decay and development: shoot the messenger to survive?
-
Vicente-Crespo M., Palacios I.M. Nonsense-mediated mRNA decay and development: shoot the messenger to survive?. Biochem Soc Trans 2010, 38:1500-1505.
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 1500-1505
-
-
Vicente-Crespo, M.1
Palacios, I.M.2
-
48
-
-
0032940802
-
Smg-7 is required for mRNA surveillance in Caenorhabditis elegans
-
Cali B.M., Kuchma S.L., Latham J., Anderson P. smg-7 is required for mRNA surveillance in Caenorhabditis elegans. Genetics 1999, 151:605-616.
-
(1999)
Genetics
, vol.151
, pp. 605-616
-
-
Cali, B.M.1
Kuchma, S.L.2
Latham, J.3
Anderson, P.4
-
49
-
-
0024444026
-
A new kind of informational suppression in the nematode Caenorhabditis elegans
-
Hodgkin J., Papp A., Pulak R., Ambros V., Anderson P. A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics 1989, 123:301-313.
-
(1989)
Genetics
, vol.123
, pp. 301-313
-
-
Hodgkin, J.1
Papp, A.2
Pulak, R.3
Ambros, V.4
Anderson, P.5
-
50
-
-
79952651144
-
Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner
-
Avery P., Vicente-Crespo M., Francis D., Nashchekina O., Alonso C.R., Palacios I.M. Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner. RNA 2011, 17:624-638.
-
(2011)
RNA
, vol.17
, pp. 624-638
-
-
Avery, P.1
Vicente-Crespo, M.2
Francis, D.3
Nashchekina, O.4
Alonso, C.R.5
Palacios, I.M.6
-
51
-
-
25844454826
-
Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster
-
Chen Z., Smith K.R., Batterham P., Robin C. Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster. Genetics 2005, 171:403-406.
-
(2005)
Genetics
, vol.171
, pp. 403-406
-
-
Chen, Z.1
Smith, K.R.2
Batterham, P.3
Robin, C.4
-
52
-
-
25844435702
-
Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets
-
Rehwinkel J., Letunic I., Raes J., Bork P., Izaurralde E. Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets. RNA 2005, 11:1530-1544.
-
(2005)
RNA
, vol.11
, pp. 1530-1544
-
-
Rehwinkel, J.1
Letunic, I.2
Raes, J.3
Bork, P.4
Izaurralde, E.5
-
53
-
-
57049126216
-
SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan
-
Huntzinger E., Kashima I., Fauser M., Saulière J., Izaurralde E. SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan. RNA 2008, 14:2609-2617.
-
(2008)
RNA
, vol.14
, pp. 2609-2617
-
-
Huntzinger, E.1
Kashima, I.2
Fauser, M.3
Saulière, J.4
Izaurralde, E.5
-
54
-
-
79955954056
-
Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish
-
doi:10.1093/nar/gkq1319
-
Anastasaki C, Longman D, Capper A, Patton EE, Cáceres JF: Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish. Nucleic Acids Res 2011, doi:10.1093/nar/gkq1319.
-
(2011)
Nucleic Acids Res
-
-
Anastasaki, C.1
Longman, D.2
Capper, A.3
Patton, E.E.4
Cáceres, J.F.5
-
55
-
-
0035862813
-
Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability
-
Medghalchi S.M., Frischmeyer P.A., Mendell J.T., Kelly A.G., Lawler A.M., Dietz H.C. Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability. Hum Mol Genet 2001, 10:99-105.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 99-105
-
-
Medghalchi, S.M.1
Frischmeyer, P.A.2
Mendell, J.T.3
Kelly, A.G.4
Lawler, A.M.5
Dietz, H.C.6
-
56
-
-
77958509175
-
Coordinate regulation of histone mRNA metabolism and DNA replication: cyclin A/cdk1 is involved in inactivation of histone mRNA metabolism and DNA replication at the end of S phase
-
Koseoglu M.M., Dong J., Marzluff W.F. Coordinate regulation of histone mRNA metabolism and DNA replication: cyclin A/cdk1 is involved in inactivation of histone mRNA metabolism and DNA replication at the end of S phase. Cell Cycle 2010, 9:3857-3863.
-
(2010)
Cell Cycle
, vol.9
, pp. 3857-3863
-
-
Koseoglu, M.M.1
Dong, J.2
Marzluff, W.F.3
-
57
-
-
77955448359
-
Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay
-
McIlwain D.R., Pan Q., Reilly P.T., Elia A.J., McCracken S., Wakeham A.C., Itie-Youten A., Blencowe B.J., Mak T.W. Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay. Proc Natl Acad Sci U S A 2010, 107:12186-12191.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 12186-12191
-
-
McIlwain, D.R.1
Pan, Q.2
Reilly, P.T.3
Elia, A.J.4
McCracken, S.5
Wakeham, A.C.6
Itie-Youten, A.7
Blencowe, B.J.8
Mak, T.W.9
-
58
-
-
44149104364
-
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
-
Weischenfeldt J., Damgaard I., Bryder D., Theilgaard-Mönch K., Thoren L.A., Nielsen F.C., Jacobsen S.E., Nerlov C., Porse B.T. NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements. Genes Dev 2008, 22:1381-1396.
-
(2008)
Genes Dev
, vol.22
, pp. 1381-1396
-
-
Weischenfeldt, J.1
Damgaard, I.2
Bryder, D.3
Theilgaard-Mönch, K.4
Thoren, L.A.5
Nielsen, F.C.6
Jacobsen, S.E.7
Nerlov, C.8
Porse, B.T.9
-
59
-
-
77955368630
-
UPF2 is a critical regulator of liver development, function and regeneration
-
Thoren L.A., Nørgaard G.A., Weischenfeldt J., Waage J., Jakobsen J.S., Damgaard I., Bergström F.C., Blom A.M., Borup R., Bisgaard H.C., et al. UPF2 is a critical regulator of liver development, function and regeneration. PLoS ONE 2010, 5:e11650.
-
(2010)
PLoS ONE
, vol.5
-
-
Thoren, L.A.1
Nørgaard, G.A.2
Weischenfeldt, J.3
Waage, J.4
Jakobsen, J.S.5
Damgaard, I.6
Bergström, F.C.7
Blom, A.M.8
Borup, R.9
Bisgaard, H.C.10
-
60
-
-
44349168303
-
Telomeres: the silence is broken
-
Azzalin C.M., Lingner J. Telomeres: the silence is broken. Cell Cycle 2008, 7:1161-1165.
-
(2008)
Cell Cycle
, vol.7
, pp. 1161-1165
-
-
Azzalin, C.M.1
Lingner, J.2
-
61
-
-
33745712580
-
Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation
-
Ciaudo C., Bourdet A., Cohen-Tannoudji M., Dietz H.C., Rougeulle C., Avner P. Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation. PLoS Genet 2006, 2:e94.
-
(2006)
PLoS Genet
, vol.2
-
-
Ciaudo, C.1
Bourdet, A.2
Cohen-Tannoudji, M.3
Dietz, H.C.4
Rougeulle, C.5
Avner, P.6
-
62
-
-
34548353924
-
Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation
-
Tarpey P.S., Raymond F.L., Nguyen L.S., Rodriguez J., Hackett A., Vandeleur L., Smith R., Shoubridge C., Edkins S., Stevens C., et al. Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation. Nat Genet 2007, 39:1127-1133.
-
(2007)
Nat Genet
, vol.39
, pp. 1127-1133
-
-
Tarpey, P.S.1
Raymond, F.L.2
Nguyen, L.S.3
Rodriguez, J.4
Hackett, A.5
Vandeleur, L.6
Smith, R.7
Shoubridge, C.8
Edkins, S.9
Stevens, C.10
-
63
-
-
70350547778
-
Human UPF1 participates in small RNA-induced mRNA downregulation
-
Jin H., Suh M.R., Han J., Yeom K.H., Lee Y., Heo I., Ha M., Hyun S., Kim V.N. Human UPF1 participates in small RNA-induced mRNA downregulation. Mol Cell Biol 2009, 29:5789-5799.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5789-5799
-
-
Jin, H.1
Suh, M.R.2
Han, J.3
Yeom, K.H.4
Lee, Y.5
Heo, I.6
Ha, M.7
Hyun, S.8
Kim, V.N.9
-
64
-
-
0037320770
-
Tissue-specific RNA surveillance? Nonsense-mediated mRNA decay causes collagen X haploinsufficiency in Schmid metaphyseal chondrodysplasia cartilage
-
Bateman J.F., Freddi S., Nattrass G., Savarirayan R. Tissue-specific RNA surveillance? Nonsense-mediated mRNA decay causes collagen X haploinsufficiency in Schmid metaphyseal chondrodysplasia cartilage. Hum Mol Genet 2003, 12:217-225.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 217-225
-
-
Bateman, J.F.1
Freddi, S.2
Nattrass, G.3
Savarirayan, R.4
-
65
-
-
33748276752
-
A homozygous frameshift mutation in the ESCO2 gene: evidence of intertissue and interindividual variation in NMD efficiency
-
Resta N., Susca F.C., Di Giacomo M.C., Stella A., Bukvic N., Bagnulo R., Simone C., Guanti G. A homozygous frameshift mutation in the ESCO2 gene: evidence of intertissue and interindividual variation in NMD efficiency. J Cell Physiol 2006, 209:67-73.
-
(2006)
J Cell Physiol
, vol.209
, pp. 67-73
-
-
Resta, N.1
Susca, F.C.2
Di Giacomo, M.C.3
Stella, A.4
Bukvic, N.5
Bagnulo, R.6
Simone, C.7
Guanti, G.8
-
66
-
-
58149093336
-
Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues
-
Zetoune A.B., Fontanière S., Magnin D., Anczuków O., Buisson M., Zhang C.X., Mazoyer S. Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues. BMC Genet 2008, 9:83.
-
(2008)
BMC Genet
, vol.9
, pp. 83
-
-
Zetoune, A.B.1
Fontanière, S.2
Magnin, D.3
Anczuków, O.4
Buisson, M.5
Zhang, C.X.6
Mazoyer, S.7
-
67
-
-
34547838641
-
The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense mediated decay pathway
-
Viegas M.H., Gehring N.H., Breit S., Hentze M.W., Kulozik A.E. The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense mediated decay pathway. Nucleic Acids Res 2007, 35:4542-4551.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 4542-4551
-
-
Viegas, M.H.1
Gehring, N.H.2
Breit, S.3
Hentze, M.W.4
Kulozik, A.E.5
-
68
-
-
32944458421
-
The human RNA surveillance factor UPF1 is required for S phase progression and genome stability
-
Azzalin C.M., Lingner J. The human RNA surveillance factor UPF1 is required for S phase progression and genome stability. Curr Biol 2006, 16:433-439.
-
(2006)
Curr Biol
, vol.16
, pp. 433-439
-
-
Azzalin, C.M.1
Lingner, J.2
-
69
-
-
37349043972
-
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends
-
Azzalin C.M., Reichenbach P., Khoriauli L., Giulotto E., Lingner J. Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 2007, 318:798-801.
-
(2007)
Science
, vol.318
, pp. 798-801
-
-
Azzalin, C.M.1
Reichenbach, P.2
Khoriauli, L.3
Giulotto, E.4
Lingner, J.5
-
70
-
-
23344452109
-
Translation termination is involved in histone mRNA degradation when DNA replication is inhibited
-
Kaygun H., Marzluff W.F. Translation termination is involved in histone mRNA degradation when DNA replication is inhibited. Mol Cell Biol 2005, 25:6879-6888.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 6879-6888
-
-
Kaygun, H.1
Marzluff, W.F.2
-
71
-
-
12944327374
-
Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay
-
Kim Y.K., Furic L., DesGroseillers L., Maquat L.E. Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay. Cell 2005, 120:195-208.
-
(2005)
Cell
, vol.120
, pp. 195-208
-
-
Kim, Y.K.1
Furic, L.2
DesGroseillers, L.3
Maquat, L.E.4
-
72
-
-
0037447232
-
Functional conservation of the telomerase protein Est1p in humans
-
Snow B.E., Erdmann N., Cruickshank J., Goldman H., Gill R.M., Robinson M.O., Harrington L. Functional conservation of the telomerase protein Est1p in humans. Curr Biol 2003, 13:698-704.
-
(2003)
Curr Biol
, vol.13
, pp. 698-704
-
-
Snow, B.E.1
Erdmann, N.2
Cruickshank, J.3
Goldman, H.4
Gill, R.M.5
Robinson, M.O.6
Harrington, L.7
-
73
-
-
2942572923
-
The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells
-
Brumbaugh K.M., Otterness D.M., Geisen C., Oliveira V., Brognard J., Li X., Lejeune F., Tibbetts R.S., Maquat L.E., Abraham R.T. The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells. Mol Cell 2004, 14:585-598.
-
(2004)
Mol Cell
, vol.14
, pp. 585-598
-
-
Brumbaugh, K.M.1
Otterness, D.M.2
Geisen, C.3
Oliveira, V.4
Brognard, J.5
Li, X.6
Lejeune, F.7
Tibbetts, R.S.8
Maquat, L.E.9
Abraham, R.T.10
-
74
-
-
68249113593
-
Common mechanisms of PIKK regulation
-
Lovejoy C.A., Cortez D. Common mechanisms of PIKK regulation. DNA Repair (Amst) 2009, 8:1004-1008.
-
(2009)
DNA Repair (Amst)
, vol.8
, pp. 1004-1008
-
-
Lovejoy, C.A.1
Cortez, D.2
-
75
-
-
33749134437
-
DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation
-
Fuller-Pace F.V. DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation. Nucleic Acids Res 2006, 34:4206-4215.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 4206-4215
-
-
Fuller-Pace, F.V.1
-
76
-
-
0037279012
-
Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1
-
Chiu S.Y., Serin G., Ohara O., Maquat L.E. Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1. RNA 2003, 9:77-87.
-
(2003)
RNA
, vol.9
, pp. 77-87
-
-
Chiu, S.Y.1
Serin, G.2
Ohara, O.3
Maquat, L.E.4
-
77
-
-
78049447110
-
SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay
-
Kashima I., Jonas S., Jayachandran U., Buchwald G., Conti E., Lupas A.N., Izaurralde E. SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. Genes Dev 2010, 24:2440-2450.
-
(2010)
Genes Dev
, vol.24
, pp. 2440-2450
-
-
Kashima, I.1
Jonas, S.2
Jayachandran, U.3
Buchwald, G.4
Conti, E.5
Lupas, A.N.6
Izaurralde, E.7
-
78
-
-
10744232514
-
Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7
-
Ohnishi T., Yamashita A., Kashima I., Schell T., Anders K.R., Grimson A., Hachiya T., Hentze M.W., Anderson P., Ohno S. Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7. Mol Cell 2003, 12:1187-1200.
-
(2003)
Mol Cell
, vol.12
, pp. 1187-1200
-
-
Ohnishi, T.1
Yamashita, A.2
Kashima, I.3
Schell, T.4
Anders, K.R.5
Grimson, A.6
Hachiya, T.7
Hentze, M.W.8
Anderson, P.9
Ohno, S.10
-
79
-
-
8844245615
-
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay
-
Unterholzner L., Izaurralde E. SMG7 acts as a molecular link between mRNA surveillance and mRNA decay. Mol Cell 2004, 16:587-596.
-
(2004)
Mol Cell
, vol.16
, pp. 587-596
-
-
Unterholzner, L.1
Izaurralde, E.2
-
80
-
-
56849103665
-
The control of mRNA decapping and P-body formation
-
Franks T.M., Lykke-Andersen J. The control of mRNA decapping and P-body formation. Mol Cell 2008, 32:605-615.
-
(2008)
Mol Cell
, vol.32
, pp. 605-615
-
-
Franks, T.M.1
Lykke-Andersen, J.2
-
81
-
-
0742288008
-
The enzymes and control of eukaryotic mRNA turnover
-
Parker R., Song H. The enzymes and control of eukaryotic mRNA turnover. Nat Struct Mol Biol 2004, 11:121-127.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 121-127
-
-
Parker, R.1
Song, H.2
-
82
-
-
52949089292
-
The exosome: a multipurpose RNA-decay machine
-
Schmid M., Jensen T.H. The exosome: a multipurpose RNA-decay machine. Trends Biochem Sci 2008, 33:501-510.
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 501-510
-
-
Schmid, M.1
Jensen, T.H.2
|