-
1
-
-
34247197937
-
The nonsense-mediated decay RNA surveillance pathway
-
Chang, Y.-F., Imam, J.S. & Wilkinson, M.F. The nonsense-mediated decay RNA surveillance pathway. Annu. Rev. Biochem. 76, 51-74 (2007).
-
(2007)
Annu. Rev. Biochem
, vol.76
, pp. 51-74
-
-
Chang, Y.-F.1
Imam, J.S.2
Wilkinson, M.F.3
-
2
-
-
0032837376
-
Nonsense-mediated mRNA decay in health and disease
-
Frischmeyer, P.A. & Dietz, H.C. Nonsense-mediated mRNA decay in health and disease. Hum. Mol. Genet. 8, 1893-1900 (1999).
-
(1999)
Hum. Mol. Genet
, vol.8
, pp. 1893-1900
-
-
Frischmeyer, P.A.1
Dietz, H.C.2
-
3
-
-
3542995089
-
Nonsense-mediated decay approaches the clinic
-
Holbrook, J.A., Neu-Yilik, G., Hentze, M.W. & Kulozik, A.E. Nonsense-mediated decay approaches the clinic. Nat. Genet. 36, 801-808 (2004).
-
(2004)
Nat. Genet
, vol.36
, pp. 801-808
-
-
Holbrook, J.A.1
Neu-Yilik, G.2
Hentze, M.W.3
Kulozik, A.E.4
-
4
-
-
6944256813
-
Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise
-
Mendell, J.T., Sharifi, N.A., Meyers, J.L., Martinez-Murillo, F. & Dietz, H.C. Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise. Nat. Genet. 36, 1073-1078 (2004).
-
(2004)
Nat. Genet
, vol.36
, pp. 1073-1078
-
-
Mendell, J.T.1
Sharifi, N.A.2
Meyers, J.L.3
Martinez-Murillo, F.4
Dietz, H.C.5
-
5
-
-
34247205419
-
An alternative branch of the nonsense-mediated decay pathway
-
Chan, W.K. et al. An alternative branch of the nonsense-mediated decay pathway. EMBO J. 26, 1820-1830 (2007).
-
(2007)
EMBO J
, vol.26
, pp. 1820-1830
-
-
Chan, W.K.1
-
6
-
-
32044454232
-
hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay
-
Wittmann, J., Hol, E.M. & Jack, H.M. hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay. Mol. Cell. Biol. 26, 1272-1287 (2006).
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 1272-1287
-
-
Wittmann, J.1
Hol, E.M.2
Jack, H.M.3
-
7
-
-
44149104364
-
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
-
Weischenfeldt, J. et al. NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements. Genes Dev. 22, 1381-1396 (2008).
-
(2008)
Genes Dev
, vol.22
, pp. 1381-1396
-
-
Weischenfeldt, J.1
-
8
-
-
2642656314
-
The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs
-
Czaplinski, K. et al. The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs. Genes Dev. 12, 1665-1677 (1998).
-
(1998)
Genes Dev
, vol.12
, pp. 1665-1677
-
-
Czaplinski, K.1
-
9
-
-
32044435368
-
Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay
-
Kashima, I. et al. Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. Genes Dev. 20, 355-367 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 355-367
-
-
Kashima, I.1
-
10
-
-
40949148553
-
Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways
-
Ivanov, P.V., Gehring, N.H., Kunz, J.B., Hentze, M.W. & Kulozik, A.E. Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways. EMBO J. 27, 736-747 (2008).
-
(2008)
EMBO J
, vol.27
, pp. 736-747
-
-
Ivanov, P.V.1
Gehring, N.H.2
Kunz, J.B.3
Hentze, M.W.4
Kulozik, A.E.5
-
11
-
-
43249084802
-
A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay
-
Singh, G., Rebbapragada, I. & Lykke-Andersen, J. A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay. PLoS Biol. 6, e111 (2008).
-
(2008)
PLoS Biol
, vol.6
-
-
Singh, G.1
Rebbapragada, I.2
Lykke-Andersen, J.3
-
12
-
-
0038814325
-
-
Gehring, N.H., Neu-Yilik, G., Schell, T., Hentze, M.W. & Kulozik, A.E. Y14 and hUpf3b form an NMD-activating complex. Mol. Cell 11, 939-949 (2003).
-
Gehring, N.H., Neu-Yilik, G., Schell, T., Hentze, M.W. & Kulozik, A.E. Y14 and hUpf3b form an NMD-activating complex. Mol. Cell 11, 939-949 (2003).
-
-
-
-
13
-
-
0035823150
-
Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex
-
Kim, V.N., Kataoka, N. & Dreyfuss, G. Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex. Science 293, 1832-1836 (2001).
-
(2001)
Science
, vol.293
, pp. 1832-1836
-
-
Kim, V.N.1
Kataoka, N.2
Dreyfuss, G.3
-
14
-
-
0034704201
-
Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon
-
Lykke-Andersen, J., Shu, M.D. & Steitz, J.A. Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon. Cell 103, 1121-1131 (2000).
-
(2000)
Cell
, vol.103
, pp. 1121-1131
-
-
Lykke-Andersen, J.1
Shu, M.D.2
Steitz, J.A.3
-
15
-
-
0034751160
-
Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)
-
Serin, G., Gersappe, A., Black, J.D., Aronoff, R. & Maquat, L.E. Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4). Mol. Cell. Biol. 21, 209-223 (2001).
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 209-223
-
-
Serin, G.1
Gersappe, A.2
Black, J.D.3
Aronoff, R.4
Maquat, L.E.5
-
16
-
-
1342308231
-
X chromosomes, retrogenes and their role in male reproduction
-
Wang, P.J. X chromosomes, retrogenes and their role in male reproduction. Trends Endocrinol. Metab. 15, 79-83 (2004).
-
(2004)
Trends Endocrinol. Metab
, vol.15
, pp. 79-83
-
-
Wang, P.J.1
-
17
-
-
12944327374
-
Mammalian Staufen1 recruits Upf1 to specific mRNA 3′ UTRs so as to elicit mRNA decay
-
Kim, Y.K., Furic, L., Desgroseillers, L. & Maquat, L.E. Mammalian Staufen1 recruits Upf1 to specific mRNA 3′ UTRs so as to elicit mRNA decay. Cell 120, 195-208 (2005).
-
(2005)
Cell
, vol.120
, pp. 195-208
-
-
Kim, Y.K.1
Furic, L.2
Desgroseillers, L.3
Maquat, L.E.4
-
18
-
-
33646865949
-
Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation
-
Kunz, J.B., Neu-Yilik, G., Hentze, M.W., Kulozik, A.E. & Gehring, N.H. Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation. RNA 12, 1015-1022 (2006).
-
(2006)
RNA
, vol.12
, pp. 1015-1022
-
-
Kunz, J.B.1
Neu-Yilik, G.2
Hentze, M.W.3
Kulozik, A.E.4
Gehring, N.H.5
-
19
-
-
33746793855
-
The regulatory utilization of genetic redundancy through responsive backup circuits
-
Kafri, R., Levy, M. & Pilpel, Y. The regulatory utilization of genetic redundancy through responsive backup circuits. Proc. Natl. Acad. Sci. USA 103, 11653-11658 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11653-11658
-
-
Kafri, R.1
Levy, M.2
Pilpel, Y.3
-
20
-
-
34548353924
-
Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation
-
Tarpey, P.S. et al. Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation. Nat. Genet. 39, 1127-1133 (2007).
-
(2007)
Nat. Genet
, vol.39
, pp. 1127-1133
-
-
Tarpey, P.S.1
-
21
-
-
0042068262
-
Complexes between the nonsense-mediated mRNA decay pathway factor human UPF1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells
-
Schell, T. et al. Complexes between the nonsense-mediated mRNA decay pathway factor human UPF1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells. Biochem. J. 373, 775-783 (2003).
-
(2003)
Biochem. J
, vol.373
, pp. 775-783
-
-
Schell, T.1
-
22
-
-
10744232514
-
Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7
-
Ohnishi, T. et al. Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7. Mol. Cell 12, 1187-1200 (2003).
-
(2003)
Mol. Cell
, vol.12
, pp. 1187-1200
-
-
Ohnishi, T.1
-
23
-
-
12344290346
-
Mechanisms of translational control by the 3′ UTR in development and differentiation
-
de Moor, C.H., Meijer, H. & Lissenden, S. Mechanisms of translational control by the 3′ UTR in development and differentiation. Semin. Cell Dev. Biol. 16, 49-58 (2005).
-
(2005)
Semin. Cell Dev. Biol
, vol.16
, pp. 49-58
-
-
de Moor, C.H.1
Meijer, H.2
Lissenden, S.3
-
24
-
-
1842473091
-
The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3
-
Kadlec, J., Izaurralde, E. & Cusack, S. The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3. Nat. Struct. Mol. Biol. 11, 330-337 (2004).
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 330-337
-
-
Kadlec, J.1
Izaurralde, E.2
Cusack, S.3
-
25
-
-
26244450884
-
Paralogs and mutational robustness linked through transcriptional reprogramming
-
Koonin, E.V. Paralogs and mutational robustness linked through transcriptional reprogramming. Bioessays 27, 865-868 (2005).
-
(2005)
Bioessays
, vol.27
, pp. 865-868
-
-
Koonin, E.V.1
-
26
-
-
34250626425
-
Meiotic sex chromosome inactivation
-
Turner, J.M. Meiotic sex chromosome inactivation. Development 134, 1823-1831 (2007).
-
(2007)
Development
, vol.134
, pp. 1823-1831
-
-
Turner, J.M.1
-
27
-
-
58149093336
-
Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues
-
Zetoune, A.B. et al. Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues. BMC Genet. 9, 83 (2008).
-
(2008)
BMC Genet
, vol.9
, pp. 83
-
-
Zetoune, A.B.1
-
28
-
-
0035983946
-
Concerted action of two dlx paralogs in sensory placode formation
-
Solomon, K.S. & Fritz, A. Concerted action of two dlx paralogs in sensory placode formation. Development 129, 3127-3136 (2002).
-
(2002)
Development
, vol.129
, pp. 3127-3136
-
-
Solomon, K.S.1
Fritz, A.2
-
29
-
-
0026440992
-
Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development
-
Rudnicki, M.A., Braun, T., Hinuma, S. & Jaenisch, R. Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development. Cell 71, 383-390 (1992).
-
(1992)
Cell
, vol.71
, pp. 383-390
-
-
Rudnicki, M.A.1
Braun, T.2
Hinuma, S.3
Jaenisch, R.4
-
30
-
-
0033485459
-
Concerted regulation and molecular evolution of the duplicated SNRPB'/B and SNRPN loci
-
Gray, T.A. et al. Concerted regulation and molecular evolution of the duplicated SNRPB'/B and SNRPN loci. Nucleic Acids Res. 27, 4577-4584 (1999).
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 4577-4584
-
-
Gray, T.A.1
-
31
-
-
0033377614
-
Pax1 and Pax9 synergistically regulate vertebral column development
-
Peters, H. et al. Pax1 and Pax9 synergistically regulate vertebral column development. Development 126, 5399-5408 (1999).
-
(1999)
Development
, vol.126
, pp. 5399-5408
-
-
Peters, H.1
-
32
-
-
0035214550
-
A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice
-
Toresson, H. & Campbell, K. A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice. Development 128, 4769-4780 (2001).
-
(2001)
Development
, vol.128
, pp. 4769-4780
-
-
Toresson, H.1
Campbell, K.2
-
33
-
-
16244414335
-
A nonimprinted Prader-Willi syndrome (PWS)-region gene regulates a different chromosomal domain in trans but the imprinted pws loci do not alter genome-wide mRNA levels
-
Stefan, M., Portis, T., Longnecker, R. & Nicholls, R.D. A nonimprinted Prader-Willi syndrome (PWS)-region gene regulates a different chromosomal domain in trans but the imprinted pws loci do not alter genome-wide mRNA levels. Genomics 85, 630-640 (2005).
-
(2005)
Genomics
, vol.85
, pp. 630-640
-
-
Stefan, M.1
Portis, T.2
Longnecker, R.3
Nicholls, R.D.4
-
34
-
-
58149097010
-
Posttranscriptional crossregulation between Drosha and DGCR8
-
Han, J. et al. Posttranscriptional crossregulation between Drosha and DGCR8. Cell 136, 75-84 (2009).
-
(2009)
Cell
, vol.136
, pp. 75-84
-
-
Han, J.1
-
35
-
-
25844512736
-
Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements
-
Gehring, N.H. et al. Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. Mol. Cell 20, 65-75 (2005).
-
(2005)
Mol. Cell
, vol.20
, pp. 65-75
-
-
Gehring, N.H.1
-
36
-
-
33744994837
-
EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3′ UTR length
-
Bühler, M., Steiner, S., Mohn, F., Paillusson, A. & Muhlemann, O. EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3′ UTR length. Nat. Struct. Mol. Biol. 13, 462-464 (2006).
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 462-464
-
-
Bühler, M.1
Steiner, S.2
Mohn, F.3
Paillusson, A.4
Muhlemann, O.5
-
37
-
-
0035862813
-
Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability
-
Medghalchi, S.M. et al. Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability. Hum. Mol. Genet. 10, 99-105 (2001).
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 99-105
-
-
Medghalchi, S.M.1
-
38
-
-
0037080771
-
T-cell receptor sequences that elicit strong downregulation of premature termination codon-bearing transcripts
-
Gudikote, J.P. & Wilkinson, M.F. T-cell receptor sequences that elicit strong downregulation of premature termination codon-bearing transcripts. EMBO J. 21, 125-134 (2002).
-
(2002)
EMBO J
, vol.21
, pp. 125-134
-
-
Gudikote, J.P.1
Wilkinson, M.F.2
-
39
-
-
0035254681
-
Splicing and 3′ end formation in the definition of nonsense-mediated decay-competent human β-globin mRNPs
-
Neu-Yilik, G. et al. Splicing and 3′ end formation in the definition of nonsense-mediated decay-competent human β-globin mRNPs. EMBO J. 20, 532-540 (2001).
-
(2001)
EMBO J
, vol.20
, pp. 532-540
-
-
Neu-Yilik, G.1
-
40
-
-
0037064145
-
Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts
-
Mendell, J.T., ap Rhys, C.M. & Dietz, H.C. Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts. Science 298, 419-422 (2002).
-
(2002)
Science
, vol.298
, pp. 419-422
-
-
Mendell, J.T.1
ap Rhys, C.M.2
Dietz, H.C.3
-
41
-
-
1442354190
-
An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay
-
Palacios, I.M., Gatfield, D., St. Johnston, D. & Izaurralde, E. An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay. Nature 427, 753-757 (2004).
-
(2004)
Nature
, vol.427
, pp. 753-757
-
-
Palacios, I.M.1
Gatfield, D.2
St. Johnston, D.3
Izaurralde, E.4
-
42
-
-
0942268832
-
Splicing enhances translation in mammalian cells: An additional function of the exon junction complex
-
Nott, A., Le Hir, H. & Moore, M.J. Splicing enhances translation in mammalian cells: an additional function of the exon junction complex. Genes Dev. 18, 210-222 (2004).
-
(2004)
Genes Dev
, vol.18
, pp. 210-222
-
-
Nott, A.1
Le Hir, H.2
Moore, M.J.3
-
43
-
-
37849005006
-
NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity
-
Chamieh, H., Ballut, L., Bonneau, F. & Le Hir, H. NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity. Nat. Struct. Mol. Biol. 15, 85-93 (2008).
-
(2008)
Nat. Struct. Mol. Biol
, vol.15
, pp. 85-93
-
-
Chamieh, H.1
Ballut, L.2
Bonneau, F.3
Le Hir, H.4
|