Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues

BMC Genetics

Volumn 9, Issue , 2008, Pages

  Zetoune, Almoutassem B ^a   Fontanière, Sandra ^a   Magnin, Delphine ^a   Anczuków, Olga ^a   Buisson, Monique ^a   Zhang, Chang X ^a   Mazoyer, Sylvie ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MEN1 PROTEIN; MESSENGER RNA; NUCLEAR PROTEIN; UNCLASSIFIED DRUG; MEN1 PROTEIN, MOUSE; ONCOPROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; EMBRYO; FIBROBLAST; GENE EXPRESSION; GENETIC DISORDER; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HEART; HETEROZYGOSITY; INTESTINE; LUNG; MOUSE; MUTANT; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; NONSENSE MUTATION; OVARY; RNA DEGRADATION; TESTIS; THYMUS; WILD TYPE; ANIMAL; ANIMAL MODEL; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; RNA STABILITY; STOP CODON;

MAMMALIA; MURINAE; MUS;

ANIMALS; CODON, NONSENSE; GENE EXPRESSION REGULATION; MICE; MODELS, ANIMAL; MODELS, GENETIC; MUTATION; NUCLEAR PROTEINS; ORGAN SPECIFICITY; PROTO-ONCOGENE PROTEINS; RNA STABILITY; RNA, MESSENGER;

EID: 58149093336     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/1471-2156-9-83     Document Type: Article

References (40)

1. Behm-Ansmant I Izaurralde E Quality control of gene expression: A stepwise assembly pathway for the surveillance complex that triggers nonsense-mediated mRNA decay Genes Dev 2006, 20(4):391-398. 10.1101/ gad.1407606 16481468
2. Scofield DG Hong X Lynch M Position of the Final Intron in Full-Length Transcripts: Determined By NMD? Mol Biol Evol 2007, 24:896-899. 10.1093/ molbev/msm010 17244600
3. Maquat LE Nonsense-mediated mRNA decay: Splicing, translation and mRNP dynamics Nat Rev Mol Cell Biol 2004, 5(2):89-99. 10.1038/nrm1310 15040442
4. Perrin-Vidoz L Sinilnikova OM Stoppa-Lyonnet D Lenoir GM Mazoyer S The nonsense-mediated mRNA decay pathway triggers degradation of most BRCA1 mRNAs bearing premature termination codons Hum Mol Genet 2002, 11(23):2805-2814. 10.1093/hmg/11.23.2805 12393792
5. Tournier I Raux G Di Fiore F Marechal I Leclerc C Martin C Wang Q Buisine MP Stoppa-Lyonnet D Olschwang S et al. Analysis of the allele-specific expression of the mismatch repair gene MLH1 using a simple DHPLC-Based Method Hum Mutat 2004, 23(4):379-384. 10.1002/ humu.20008 15024732
6. Buisson M Anczukow O Zetoune AB Ware MD Mazoyer S The 185delAG mutation (c.68_69delAG) in the BRCA1 gene triggers translation reinitiation at a downstream AUG codon Hum Mutat 2006, 27(10):1024-1029. 10.1002/ humu.20384 16941470
7. Paulsen M Lund C Akram Z Winther JR Horn N Moller LB Evidence that translation reinitiation leads to a partially functional Menkes protein containing two copper-binding sites Am J Hum Genet 2006, 79(2):214-229. 1559486 16826513 10.1086/505407
8. Puel A Reichenbach J Bustamante J Ku CL Feinberg J Doffinger R Bonnet M Filipe-Santos O Beaucoudrey L Durandy A et al.: The NEMO mutation creating the most-upstream premature stop codon is hypomorphic because of a reinitiation of translation Am J Hum Genet 2006, 78(4):691-701. 1424680 16532398 10.1086/501532
9. Disset A Bourgeois CF Benmalek N Claustres M Stevenin J Tuffery-Giraud S An exon skipping-associated nonsense mutation in the dystrophin gene uncovers a complex interplay between multiple antagonistic splicing elements Hum Mol Genet 2006, 15(6):999-1013. 10.1093/hmg/ddl015 16461336
10. Holbrook JA Neu-Yilik G Hentze MW Kulozik AE Nonsense-mediated decay approaches the clinic Nat Genet 2004, 36(8):801-808. 10.1038/ng1403 15284851
11. Khajavi M Inoue K Lupski JR Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease Eur J Hum Genet 2006, 14(10):1074-1081. 10.1038/sj.ejhg.5201649 16757948
12. Hall GW Thein S Nonsense codon mutations in the terminal exon of the beta-globin gene are not associated with a reduction in beta-mRNA accumulation: A mechanism for the phenotype of dominant beta-thalassemia Blood 1994, 83(8):2031-2037. 8161774
13. Inoue K Khajavi M Ohyama T Hirabayashi S Wilson J Reggin JD Mancias P Butler IJ Wilkinson MF Wegner M et al.: Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations Nat Genet 2004, 36(4):361-369. 10.1038/ng1322 15004559
14. Bateman JF Freddi S Nattrass G Savarirayan R Tissue-specific RNA surveillance? Nonsense-mediated mRNA decay causes collagen X haploinsufficiency in Schmid metaphyseal chondrodysplasia cartilage Hum Mol Genet 2003, 12(3):217-225. 10.1093/hmg/ddg054 12554676
15. Forsberg L Zablewska B Piehl F Weber G Lagercrantz S Gaudray P Hoog C Larsson C Differential expression of multiple alternative spliceforms of the Men1 tumor suppressor gene in mouse Int J Mol Med 2001, 8(6):681-689. 11712086
16. Stewart C Parente F Piehl F Farnebo F Quincey D Silins G Bergman L Carle GF Lemmens I Grimmond S et al.: Characterization of the mouse Men1 gene and its expression during development Oncogene 1998, 17(19):2485-2493. 10.1038/sj.onc.1202164 9824159
17. Bertolino P Tong WM Galendo D Wang ZQ Zhang CX Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1 Mol Endocrinol 2003, 17(9):1880-1892. 10.1210/ me.2003-0154 12819299
18. Bassett JH Rashbass P Harding B Forbes SA Pannett AA Thakker RV Studies of the murine homolog of the multiple endocrine neoplasia type 1 (MEN1) gene, men1 J Bone Miner Res 1999, 14(1):3-10. 10.1359/jbmr.1999.14.1.3 9893060
19. Guru SC Crabtree JS Brown KD Dunn KJ Manickam P Prasad NB Wangsa D Burns AL Spiegel AM Marx SJ et al.: Isolation, genomic organization, and expression analysis of Men1, the murine homolog of the MEN1 gene Mamm Genome 1999, 10(6):592-596. 10.1007/s003359901051 10341092
20. Ferraiuolo MA Lee CS Ler LW Hsu JL Costa-Mattioli M Luo MJ Reed R Sonenberg N A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay Proc Natl Acad Sci USA 2004, 101(12):4118-4123. 384704 15024115 10.1073/ pnas.0400933101
21. Mendell JT ap Rhys CM Dietz HC Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts Science 2002, 298(5592):419-422. 10.1126/science.1074428 12228722
22. Gehring NH Kunz JB Neu-Yilik G Breit S Viegas MH Hentze MW Kulozik AE Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements Mol Cell 2005, 20(1):65-75. 10.1016/j.molcel.2005.08.012 16209946
23. Perlick HA Medghalchi SM Spencer FA Kendzior RJ Jr Dietz HC Mammalian orthologues of a yeast regulator of nonsense transcript stability Proc Natl Acad Sci USA 1996, 93(20):10928-10932. 38260 8855285 10.1073/ pnas.93.20.10928
24. Mendell JT Medghalchi SM Lake RG Noensie EN Dietz HC Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes Mol Cell Biol 2000, 20(23):8944-8957. 86549 11073994 10.1128/MCB.20.23.8944-8957.2000
25. Zhao XF Colaizzo-Anas T Nowak NJ Shows TB Elliott RW Aplan PD The mammalian homologue of mago nashi encodes a serum-inducible protein Genomics 1998, 47(2):319-322. 10.1006/geno.1997.5126 9479507
26. Macchi P Kroening S Palacios IM Baldassa S Grunewald B Ambrosino C Goetze B Lupas A St Johnston D Kiebler M Barentsz, a new component of the Staufen-containing ribonucleoprotein particles in mammalian cells, interacts with Staufen in an RNA-dependent manner J Neurosci 2003, 23(13):5778-5788. 12843282
27. Li Q Imataka H Morino S Rogers GW Jr Richter-Cook NJ Merrick WC Sonenberg N Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII Mol Cell Biol 1999, 19(11):7336-7346. 84727 10523622
28. Gudikote JP Imam JS Garcia RF Wilkinson MF RNA splicing promotes translation and RNA surveillance Nat Struct Mol Biol 2005, 12(9):801-809. 10.1038/nsmb980 16116435
29. Viegas MH Gehring NH Breit S Hentze MW Kulozik AE The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway Nucleic Acids Res 2007, 35(13):4542-4551. 1935013 17586820 10.1093/nar/ gkm461
30. Tan JT Kremer F Freddi S Bell KM Baker NL Lamande SR Bateman JF Competency for nonsense-mediated reduction in collagen X mRNA is specified by the 3′ UTR and corresponds to the position of mutations in Schmid metaphyseal chondrodysplasia Am J Hum Genet 2008, 82(3):786-793. 10.1016/j.ajhg.2008.01.006 18304492
31. Linde L Boelz S Nissim-Rafinia M Oren YS Wilschanski M Yaacov Y Virgilis D Neu-Yilik G Kulozik AE Kerem E et al.: Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin J Clin Invest 2007. 1783999 17290305
32. Resta N Susca FC Di Giacomo MC Stella A Bukvic N Bagnulo R Simone C Guanti G A homozygous frameshift mutation in the ESCO2 gene: Evidence of intertissue and interindividual variation in Nmd efficiency J Cell Physiol 2006, 209(1):67-73. 10.1002/jcp.20708 16775838
33. Bahassi el M Penner CG Robbins SB Tichy E Feliciano E Yin M Liang L Deng L Tischfield JA Stambrook PJ The breast cancer susceptibility allele CHEK2*1100delC promotes genomic instability in a knock-in mouse model Mutat Res 2007, 616(1-2):201-209. 17174984
34. Barber RD Harmer DW Coleman RA Clark BJ GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues Physiol Genomics 2005, 21(3):389-395. 10.1152/physiolgenomics.00025.2005 15769908
35. Mendell JT Sharifi NA Meyers JL Martinez-Murillo F Dietz HC Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise Nat Genet 2004, 36(10):1073-1078. 10.1038/ng1429 15448691
36. Linde L Boelz S Neu-Yilik G Kulozik AE Kerem B The efficiency of nonsense-mediated mRNA decay is an inherent character and varies among different cells Eur J Hum Genet 2007, 15(11):1156-1162. 10.1038/ sj.ejhg.5201889 17625509
37. Ware MD DeSilva D Sinilnikova OM Stoppa-Lyonnet D Tavtigian SV Mazoyer S Does nonsense-mediated mRNA decay explain the ovarian cancer cluster region of the BRCA2 gene? Oncogene 2006, 25(2):323-328. 16170354
38. Wang ZQ Auer B Stingl L Berghammer H Haidacher D Schweiger M Wagner EF Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease Genes Dev 1995, 9(5):509-520. 10.1101/ gad.9.5.509 7698643
39. Sullivan LM Dukes KA Losina E Tutorial in biostatistics. An introduction to hierarchical linear modelling Stat Med 1999, 18(7):855-888. 10.1002/ (SICI)1097-0258(19990415)18:7<855::AID-SIM117>3.0.CO;2-7 10327531
40. R: A Language and Environment for Statistical Computing Vienna, Austria 2004